Home  About us  Contact
 

Palladium-Catalyzed Coupling Reactions (Palladium-Catalyze + coupling_reaction)

Distribution by Scientific Domains
Chemistry100%

Selected Abstracts

ChemInform Abstract: Microwave-Assisted Intramolecular Cyclization of Electron-Rich Heterocycle Derivatives by a Palladium-Catalyzed Coupling Reaction.

CHEMINFORM, Issue 22 2008
Egle M. Beccalli
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

ChemInform Abstract: Synthesis of Unsymmetrical Biaryls via Palladium-Catalyzed Coupling Reaction of Aryl Halides.

CHEMINFORM, Issue 9 2001
Jwanro Hassan
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

Recent Applications of Palladium-Catalyzed Coupling Reactions in the Pharmaceutical, Agrochemical, and Fine Chemical Industries

ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 18 2009
Christian Torborg
Abstract Palladium-catalyzed coupling reactions have become a central tool for the synthesis of biologically active compounds both in academia and industry. Most of these transformations make use of easily available substrates and allow for a shorter and more selective preparation of substituted arenes and heteroarenes compared to non-catalytic pathways. Notably, molecular-defined palladium catalysts offer high chemoselectivity and broad functional group tolerance. Considering these advantages, it is not surprising that several palladium-catalyzed coupling reactions have been implemented in the last decade into the industrial manufacture of pharmaceuticals and fine chemicals. In this review different examples from 2001,2008 are highlighted, which have been performed at least on a kilogram scale in the chemical and pharmaceutical industries. [source]

Microwave-Enhanced Palladium-Catalyzed Coupling Reactions: A Diversity-Oriented Synthesis Approach to Functionalized Flavones.

CHEMINFORM, Issue 13 2007
Richard J. Fitzmaurice
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]

A Convenient Diversification of Pyrrolo[2,3-b]quinolines by Iodonation and Palladium-Catalyzed Coupling Reactions.

CHEMINFORM, Issue 19 2004
Won Jung Lee
Abstract For Abstract see ChemInform Abstract in Full Text. [source]

ChemInform Abstract: Studies of Palladium-Catalyzed Coupling Reactions for Preparation of Hindered 3-Arylpyrroles Relevant to (-)-Rhazinilam and Its Analogues.

CHEMINFORM, Issue 26 2002
Leon Ghosez
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

ChemInform Abstract: Palladium-Catalyzed Coupling Reactions of Biphenylene with Olefins, Arylboronic Acids, and Ketones Involving C,C Bond Cleavage.

CHEMINFORM, Issue 41 2001
Tetsuya Satoh
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

ChemInform Abstract: Syntheses of Acetylquinolines and Acetylisoquinolines via Palladium-Catalyzed Coupling Reactions.

CHEMINFORM, Issue 32 2001
Jean-Yves Legros
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

Efficient Preparation of Photoswitchable Dithienylethene-Linker-Conjugates by Palladium-Catalyzed Coupling Reactions of Terminal Alkynes with Thienyl Chlorides and Other Aryl Halides

CHEMISTRY - AN ASIAN JOURNAL, Issue 5 2010
Marc Zastrow
Abstract Three photochromic dithienylethene-linker-conjugates with an adamantane core containing different spacer lengths and footprint areas with carboxylic anchoring groups are synthesized. The synthetic routes start either from the ethynylene-linker 5 or the iodo-substituted linker 8. Reaction conditions for the final Sonogashira coupling step between ethynylene-linker 5 with the chloro-substituted dithienylethene 4 in the presence of [PdCl2(CH3CN)2]/X-Phos and Cs2CO3 or K3PO4 are optimized using 2-chloro-5-methylthiophene (9) and triethylsilylacetylene or triisopropylsilylacetylene (10,a,b) as model compounds. Experimental conditions are found to suppress the activation of the C(sp)Si bond in TIPS-acetylene 10,b, a reaction leading to a subsequent cross-coupling reaction to form by-product 12. Furthermore, activation of the C(sp)Si bond in the presence of the fluorinated backbone of the chloro-substituted dithienylethene 4 can also be prevented. The photochromic properties of the conjugate 3 and its precursor dithienylethene 7,b are also investigated. Beschrieben wird die Synthese von drei photochromen Dithienylethen-Linker-Konjugaten, bestehend aus einer zentralen Adamantaneinheit, Carbonsäure-Ankergruppen, sowie variierenden "Spacerlängen" und unterschiedlichen Fußabdrücken. Die synthetischen Routen zu diesen Verbindungen beginnen entweder ausgehend von dem Ethinylen-Linker 5 oder von dem Iod-substituierten Linker 8. Für die finale Sonogashira-Kupplung wurden dabei Reaktionsbedingungen zwischen dem Ethinylen-Linker 5 und dem Chlor-substituierten Dithienylethen 4 in Gegenwart von [PdCl2(CH3CN)2]/X-Phos und Cs2CO3 oder K3PO4 verwendet, die anhand von Modellstudien mit 2-Chlor-5-methylthiophen (9) und Triethylsilylacetylen oder Triisopropylsilylacetylen (10,a,b) optimiert wurden. Dabei wurden experimentelle Bedingungen gefunden, um die Aktivierung der C(sp)-Si-Bindung von TIPS-Acetylen 10,b zu unterdrücken, welche ansonsten zu dem Nebenprodukt 12 führte. Darüber hinaus konnte die Aktivierung der C(sp)-Si-Bindung in Anwesenheit des fluorierten Rückgrats des chlor-substituierten Dithienylethen 4 verhindert werden. Schließlich wurden die photochromen Eigenschaften des Konjugates 3 und der Vorläuferverbindung 7,b untersucht. [source]