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Paediatric Oncology (paediatric + oncology)

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Selected Abstracts

UICC-2002 TNM classification is not suitable for differentiated thyroid cancer in children and adolescents

PEDIATRIC BLOOD & CANCER, Issue 6 2008
Prasad T. Oommen MD
Abstract Background Recently the UICC-TNM classification for differentiated thyroid cancer (DTC) was changed neglecting the special circumstances for children affected by the disease. While the 1997 TNM classification grouped tumours ,1 cm as T1, the 2002 system changed this to a margin of ,2 cm. The consequences of this change were evaluated by analysing patients enrolled in the multicentre interdisciplinary therapy study of the German Society of Paediatric Oncology and Haematology (GPOH) on malignant endocrine tumours in children and adolescents, GPOH-MET 97. Procedure Between 1998 and 2005, 82 patients with histologically proven DTC entered the study. Patients classified according to UICC-TNM classification 1997 were reclassified according to the new classification (2002/2003) and vice versa by cross checking with original pathologist's reports. Results Twenty males and 62 females at a mean age of 12.5 years were evaluated. We observed a definite shift from patients formerly classified as T2 (1,4 cm) to category T1 (,2 cm) according to the 2002 TNM classification. Among these patients a threefold increase of lymph node involvement and/or distant metastases could be demonstrated. Conclusions The 2002 UICC-classification may have a disadvantage for children with tumours measuring between 1 and 2 cm, as those are now classified as T1. A high rate of lymph node involvement in this group reflects the risk of under-diagnosis and -treatment of this group. The current TNM classification for DTC in children should be changed taking the physiological and anatomical differences between children and adults into consideration. Pediatr Blood Cancer 2008;50:1159,1162. © 2007 Wiley-Liss, Inc. [source]

International Society of Paediatric Oncology, SIOP XXXVIII Congress Meeting: Contents and Abstracts

PEDIATRIC BLOOD & CANCER, Issue 4 2006
Article first published online: 24 AUG 200
First page of article [source]

International Society of Paediatric Oncology, SIOP XXXVII Annual Congress Meeting: Contents

PEDIATRIC BLOOD & CANCER, Issue 4 2005
Article first published online: 26 AUG 200
No abstract is available for this article. [source]

International Society of Paediatric Oncology, SIOP XXXVII Annual Congress Meeting: Abstracts

PEDIATRIC BLOOD & CANCER, Issue 4 2005
Article first published online: 26 AUG 200
First page of article [source]

International Society of Paediatric Oncology, SIOP XXXVI Congress Meeting: Abstracts

PEDIATRIC BLOOD & CANCER, Issue 4 2004
Article first published online: 17 JUL 200
First page of article [source]

Lessons for neurology from paediatric oncology

DEVELOPMENTAL MEDICINE & CHILD NEUROLOGY, Issue 1 2007
Michael Pike
[source]

Burnout, psychiatric morbidity, and work-related sources of stress in paediatric oncology staff: a review of the literature

PSYCHO-ONCOLOGY, Issue 10 2009
Suzanne Mukherjee
Abstract Objective: A growing body of research suggests that staff working in adult oncology services are at risk of burnout and psychiatric morbidity, but whether or not these findings can be generalised to staff working in paediatric oncology is questionable. This paper reports the findings of a comprehensive review of the literature on burnout, psychiatric morbidity, and sources of work-related stress in paediatric oncology staff. Methods: Electronic searches of MEDLINE and PSYCHINFO. This was followed by a screening process, during which papers where checked against inclusion and exclusion criteria, and the quality of study reporting was assessed. Information about the study design and methods was then extracted from each paper so that the methodological quality could be critiqued. Results: Ten studies meeting the review inclusion criteria were identified. No studies were identified which compared paediatric and adult oncology staff. Research on paediatric oncology staff has failed to use the well-established standardised measures of burnout and psychiatric morbidity employed in studies of adult oncology staff. There is some qualitative evidence to suggest paediatric oncology nurses experience a unique, additional set of stressors not encountered by colleagues in adult oncology services. Conclusion: The evidence on stress and burnout in paediatric oncology staff is extremely limited. In order to devise appropriate and effective interventions to support staff, we need to have a much better understanding of the level of burnout and psychiatric morbidity experienced by all members of the paediatric oncology multi-disciplinary team, as well as the factors that contribute to these experiences. Copyright © 2009 John Wiley & Sons, Ltd. [source]

Evidence-based paediatric oncology, 2nd edition

ACTA PAEDIATRICA, Issue 12 2009
Thomas Wiebe
No abstract is available for this article. [source]