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P Ligand (p + ligand)
Selected AbstractsMixtures of Chiral Phosphorous Acid Diesters and Achiral P Ligands in the Enantio- and Diastereoselective Hydrogenation of Ketimines.CHEMINFORM, Issue 40 2007Manfred T. Reetz Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Preparation and Coordination Chemistry of n -AllylaminophosphaneEUROPEAN JOURNAL OF INORGANIC CHEMISTRY, Issue 4 2005Alexandra M. Z. Slawin Abstract Reaction of allylamine with 1 equiv. of Ph2PCl in the presence of NEt3, proceeds in THF to give (allylamino)phosphane 1. 1 has been coordinated as a monodentate P ligand with Au, Pd, Pt, Ru, Rh, Ir and as a bidentate P,allyl ligand to Pt. Reaction of KOtBu with [PtCl2{Ph2PNH(C3H5)}2] in methanol gives [Pt{Ph2PNH(C3H8O)}2]. The X-ray structures of 1.Se and four demonstrative monodentate complexes all reveal intramolecular N,H···Cl hydrogen bonding. The structure of [Pt{Ph2PNH(C3H8O)}2] consists of an N,H···O hydrogen-bonded dimer in the solid state. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005) [source] SELPLG Gene Polymorphisms in Relation to Plasma SELPLG Levels and Coronary Artery DiseaseANNALS OF HUMAN GENETICS, Issue 6 2003D. A. Tregouet Summary P-selectin and P-selectin glycoprotein ligand (SELPLG, selectin P ligand) constitute a receptor/ligand complex that is likely to be involved in the development of atherosclerosis and its complications. While the genetic variability of P-selectin has already been investigated in depth, that of the SELPLG gene has not yet been extensively explored. The coding and regulatory sequences of the SELPLG were screened and nine polymorphisms were identified. The identified polymorphisms were genotyped in the AtheroGene study, a case-control study of coronary artery disease (CAD). Haplotype analysis revealed that two polymorphisms of SELPLG, the M62I and the VNTR, independently influenced plasma SELPLG levels. Conversely, haplotypes of SELPLG were not associated with CAD risk. [source] Copper Complexes with (2,7-Di- tert -butylfluoren-9-ylidene)methanedithiolate: Oxidatively Promoted Dithioate Condensation,EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, Issue 1 2006José Vicente Abstract The reaction of [Cu(NCMe)4]PF6 with piperidinium 2,7-di- tert -butyl-9H -fluorene-9-carbodithioate (pipH)[S2C(tBu-Hfy)] (1; tBu-Hfy = 2,7-di- tert -butylfluoren-9-yl), affords [Cun{S2C(tBu-Hfy)}n] (2), which reacts with various P ligands to give [Cu{S2C(tBu-Hfy)}L2] [L = PPh3 (3a), PCy3 (3b), PiPr3 (3d); L2 = 1,1,-bis(diphenylphosphanyl)ferrocene (dppf, 3c), bis(diphenylphosphanyl)methane (dppm, 3e)]. Compounds 3a,c react with atmospheric oxygen and moisture in the presence of NEt3 to give the dinuclear complexes [Cu2{[SC=(tBu-fy)]2S}L2] [tBu-fy = 2,7-di- tert -butylfluoren-9-ylidene; L = PPh3 (4a), PCy3 (4b); L2 = dppf (4c)], which contain a new dithiolato ligand formally resulting from the condensation of two dithioato ligands with loss of a sulfide ion and two protons. Neutral CuI dithiolate complexes of the type [Cu4{S2C=(tBu-fy)}2L4] [S2C=(tBu-fy) = [2,7-di- tert -butylfluoren-9-ylidene)methanedithiolate; L = PPh3 (5a), P(C6H4OMe- p)3 (5b), PiPr3 (5d) or L2 = dppf (5c)] were obtained by treating 1 with [Cu(NCMe)4]PF6, the corresponding phosphane, and piperidine in a 1:2:2:1 molar ratio. The reaction of 1 with Cu(ClO4)2·6H2O and (Pr4N)OH in a 2:1:2 molar ratio gives the CuII complex (Pr4N)2[Cu{S2C=(tBu-fy)}2] [(Pr4N)26], which readily oxidizes to the CuIII complex Pr4N[Cu{S2C=(tBu-fy)}2] (Pr4N7) in the presence of atmospheric oxygen and moisture. The salt PPN7 [PPN+ =(Ph3P)2N+] was obtained from 1, CuCl2·2H2O, PPNCl, and piperidine in a 2:1:1:2 molar ratio under aerobic conditions. The crystal structures of 3a, 3c·CH2Cl2, 4a·4Me2CO, and 4c·CH2Cl2 have been determined by X-ray diffraction studies. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006) [source] Preparation of Chiral Homoannularly Bridged N,P-Ferrocenyl Ligands by Intramolecular Coupling of 1,5-Dilithioferrocenes and Their Application in Asymmetric Allylic Substitution Reactions,EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 33 2007Shin-ichi Fukuzawa Abstract Homoannularly bridged ferrocene 6b was prepared by intramolecular coupling of 1,5-dilithioferrocene 5b mediated by Fe(acac)3. Dilithioferrocene 5b was prepared by lithium,halogen exchange of the corresponding diiodide, which was prepared by 1,5-dilithiation of the o -TMS-blocked ferrocene and followed by trapping with iodine and removal of the TMS group. Alternatively, 5b could be readily prepared by the reaction of o -bromophenylferrocene 8 with nBuLi (>2 equiv.). The benzene ring of 6b underwent ortho lithiation with tBuLi, and the resulting lithiated species was trapped with Ph2PCl to produce corresponding aminophosphane 7d. Aminophosphane 13, which has the phosphanyl group on the cyclopentadienyl ring, was prepared by intramolecular coupling of 1,5-dilithiated PhPPFA 11 mediated by Fe(acac)3. New N,P ligands 7d and 13 were used in the palladium-catalyzed allylic alkylation and amination of 1,3-diphenyl-2-propenyl acetate (14), and ligand 7d was found to give good yields with enantioselectivities as high as 96,% ee. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007) [source] 1,1,-P/O-Ferrocenyl Ligands in Palladium-Catalyzed Suzuki Coupling of Aryl Chlorides.CHEMINFORM, Issue 25 2006Shihui Teo Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] | ||||||||||