Overweight People (overweight + people)

Distribution by Scientific Domains


Selected Abstracts


Body mass index, chronic atrophic gastritis and heartburn: a population-based study among 8936 older adults from Germany

ALIMENTARY PHARMACOLOGY & THERAPEUTICS, Issue 2 2010
L. Gao
Aliment Pharmacol Ther 2010; 32: 296,302 Summary Background, Obesity and overweight have been positively related to gastro-oesophageal reflux disease (GERD). It has been suggested that this relationship is as a consequence of an increased gastric acid reflux, which is caused by an enhanced intra-abdominal pressure. Aim, To assess potential interaction of the association between body mass index (BMI) and GERD by chronic atrophic gastritis, which goes along with decreased acid production. Methods, In the baseline examination of ESTHER, a study conducted in 9953 older adults in Saarland, information on frequency of heartburn, potential risk factors and medical history was obtained by self-administered standardized questionnaire. Serological measurements of pepsinogen I and II were taken for definition of chronic atrophic gastritis. Results, In total, 2565 (28.7%) of the included subjects experienced heartburn within the previous 4 weeks. A pronounced dose-response relationship was observed between BMI and heartburn occurrence (P < 0.001) among people without chronic atrophic gastritis, but not among people with chronic atrophic gastritis (P -value for interaction = 0.018). Obese/overweight people with chronic atrophic gastritis had a much lower risk of heartburn compared with obese/overweight people without chronic atrophic gastritis (OR = 0.31, 95% CI = 0.24,0.40). Conclusion, Our results are consistent with the hypothesis that BMI is related positively to GERD symptoms by its impact on acid reflux. [source]


The Effect of Weight Loss on Perceptions of Weight Controllability: Implications for Prejudice Against Overweight People

JOURNAL OF APPLIED BIOBEHAVIORAL RESEARCH, Issue 1 2002
Bruce E. Blaine
The influence of weight and recent weight loss on perceptions of weight controllability and prejudice against overweight people was investigated. Participants (N= 64) examined bogus health, diet, and fitness information about a female target. The target's weight (121 vs. 161 lb, or 55 vs. 73 kg) and recent weight loss (0 vs. 40 lb, or 0 vs. 18 kg) were manipulated. Perceptions of the controllability of weight, trait ratings of the target, and dislike of overweight people were measured. The results showed that weight loss increases perceptions of the controllability of weight equally in normal and overweight targets. Moreover, overweight targets were disliked more and judged more unattractive than were targets with more healthy weights, and this was particularly true for overweight targets who had recently lost weight. The implications of the results for prejudice against overweight people and the stigma of obesity are discussed. [source]


Body mass index, chronic atrophic gastritis and heartburn: a population-based study among 8936 older adults from Germany

ALIMENTARY PHARMACOLOGY & THERAPEUTICS, Issue 2 2010
L. Gao
Aliment Pharmacol Ther 2010; 32: 296,302 Summary Background, Obesity and overweight have been positively related to gastro-oesophageal reflux disease (GERD). It has been suggested that this relationship is as a consequence of an increased gastric acid reflux, which is caused by an enhanced intra-abdominal pressure. Aim, To assess potential interaction of the association between body mass index (BMI) and GERD by chronic atrophic gastritis, which goes along with decreased acid production. Methods, In the baseline examination of ESTHER, a study conducted in 9953 older adults in Saarland, information on frequency of heartburn, potential risk factors and medical history was obtained by self-administered standardized questionnaire. Serological measurements of pepsinogen I and II were taken for definition of chronic atrophic gastritis. Results, In total, 2565 (28.7%) of the included subjects experienced heartburn within the previous 4 weeks. A pronounced dose-response relationship was observed between BMI and heartburn occurrence (P < 0.001) among people without chronic atrophic gastritis, but not among people with chronic atrophic gastritis (P -value for interaction = 0.018). Obese/overweight people with chronic atrophic gastritis had a much lower risk of heartburn compared with obese/overweight people without chronic atrophic gastritis (OR = 0.31, 95% CI = 0.24,0.40). Conclusion, Our results are consistent with the hypothesis that BMI is related positively to GERD symptoms by its impact on acid reflux. [source]


The addition of metformin in type 1 diabetes improves insulin sensitivity, diabetic control, body composition and patient well-being

DIABETES OBESITY & METABOLISM, Issue 1 2007
R. J. Moon
Aim:, As many overweight people with T1DM are insulin resistant, adjuvant therapy with insulin sensitising agents, such as metformin, may be beneficial. This study evaluated the effect of adjuvant metformin in T1DM on insulin sensitivity, diabetic control, body composition, quality of life (QOL) and treatment satisfaction. Materials and Methods:, A 3-month prospective open-labelled pilot study of 16 patients aged 18-40 with T1DM and body mass index (BMI) >25 kg/m2 was performed. The patients received 500-850 mg metformin twice daily. Insulin sensitivity, assessed by a frequently sampled intravenous glucose tolerance test [n=5], body composition, HbA1c and quality of life (QOL) were measured before and after treatment. A retrospective review of 30 patients with T1DM treated with metformin for at least 4 months was also performed. BMI, HbA1c and insulin requirements during metformin treatment was compared to pre-metformin data, and to patients treated with insulin only. Results:, In the pilot study, insulin sensitivity increased significantly from 0.86 0.33 10,4/min/(U/ml) to 1.17 0.48 10,4/min/(U/ml) after 3 months adjuvant therapy (p = 0.043). This was associated with a decreased insulin requirement and mean daily blood glucose. There were no significant changes in HbA1c or body composition. QOL significantly improved (p < 0.002). The retrospective review revealed an initial reduction in HbA1c (0.8 1.4%, p = 0.001). This effect diminished with prolonged treatment. BMI decreased in patients remaining on metformin for a 2-year period (0.5 0.5kg/m2, p = 0.042). Conclusion:, Adjuvant metformin can improve QOL, insulin sensitivity and glycaemic control in overweight adults with T1DM. [source]


The Effect of Weight Loss on Perceptions of Weight Controllability: Implications for Prejudice Against Overweight People

JOURNAL OF APPLIED BIOBEHAVIORAL RESEARCH, Issue 1 2002
Bruce E. Blaine
The influence of weight and recent weight loss on perceptions of weight controllability and prejudice against overweight people was investigated. Participants (N= 64) examined bogus health, diet, and fitness information about a female target. The target's weight (121 vs. 161 lb, or 55 vs. 73 kg) and recent weight loss (0 vs. 40 lb, or 0 vs. 18 kg) were manipulated. Perceptions of the controllability of weight, trait ratings of the target, and dislike of overweight people were measured. The results showed that weight loss increases perceptions of the controllability of weight equally in normal and overweight targets. Moreover, overweight targets were disliked more and judged more unattractive than were targets with more healthy weights, and this was particularly true for overweight targets who had recently lost weight. The implications of the results for prejudice against overweight people and the stigma of obesity are discussed. [source]


Prevalence of gallstone disease in Iran

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, Issue 5 2001
Sadegh Massarrat
Abstract Background: Prevalence of gallstone disease is different depending on the geographic region involved. Few studies, in Asia but not from Iran, about the frequency of gallstone disease have been published. The aim of this study is to examine the prevalence of gallstone disease in Iran. Methods: Four hundred and seventy-seven nomads from southern Iran, 513 industrial laborers older than 34 years, and 421 laborers from a pharmaceutical company above 30 years of age, and 471 elderly persons from three nursing homes near Tehran underwent abdominal sonography. Results: There were 1373 men and 509 women. Eighty-nine subjects had gallstone disease and 10.1% of them were cholecystectomized. While the prevalence in the men and women in the age group 31,40 years was very low (0.3% in men and 1.8% in women), it increases sharply in men older than 60 years and women older than 50 years to more than 10-fold (12.5 and 24.6% in male and female with an age 71,80 years, respectively). Conclusion: In Iran, gallstone disease is very uncommon in middle-aged people, but increases sharply in older people. However, this does not reach the high prevalence seen in Western countries. The intake of a high fiber-containing diet, a low number of overweight people, smoking habit and hyperlipidemia are probably the cause for this low prevalence. [source]