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Other Complexes (other + complex)
Selected AbstractsSynthesis of Polysubstituted 3-Iodopyrans by Electrophilic CyclizationEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 14 2009Yong-Xin Xie Abstract A variety of polysubstituted 3-iodopyrans were readily prepared in good to excellent yield under mild reaction conditions by the reaction of alkynyl carboxamides with ICl, I2, and NIS. The products obtained from this process are versatile materials that can be used to construct other complex functionalized pyran structures of importance. The occurrence of the pyranyl group in both natural products and pharmaceuticals confers important value to this study. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009) [source] Pro-inflammatory biomarkers during experimental gingivitis in patients with type 1 diabetes mellitus: a proof-of-concept studyJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 1 2010Giovanni E. Salvi Abstract Aim: To compare gingival crevicular fluid (GCF) biomarker levels and microbial distribution in plaque biofilm (SP) samples for subjects with type 1 diabetes (T1DM) versus healthy subjects without diabetes during experimental gingivitis (EG). Materials and Methods: A total of nine T1DM patients and nine healthy controls of age and gender similar to the T1DM patients were monitored for 35 days during EG. Hygiene practices were stopped for 3 weeks, and GCF, SP, plaque index (PI) and gingival index were determined. IL-1,, IL-8, MMP-8 and MMP-9 were quantified by enzyme-linked immunosorbent assay, and SP samples were assessed by DNA,DNA hybridization for a panel of 40 subgingival microbial species. Results: IL-1, levels in T1DM patients were elevated compared with healthy individuals, and showed differences between groups at 7,21 days while healthy patients showed IL-1, increases from baseline to 14,21 days (p<0.05). Differences were observed in MMP-9 levels between patients with and without T1DM at 7,14 days (p<0.05). Orange complex species and PI measurements displayed a superior correlation with biomarker levels when compared with other complexes or clinical measurements during EG. Conclusions: The mean GCF biomarker levels for IL-1, and MMP-8 were most significantly elevated in T1DM subjects compared with healthy individuals during EG, not resulting from differences in the mean PI or microbial composition. [source] Transient complexes of redox proteins: structural and dynamic details from NMR studiesJOURNAL OF MOLECULAR RECOGNITION, Issue 6 2004Miguel Prudêncio Abstract Redox proteins participate in many metabolic routes, in particular those related to energy conversion. Protein,protein complexes of redox proteins are characterized by a weak affinity and a short lifetime. Two-dimensional NMR spectroscopy has been applied to many redox protein complexes, providing a wealth of information about the process of complex formation, the nature of the interface and the dynamic properties of the complex. These studies have shown that some complexes are non-specific and exist as a dynamic ensemble of orientations while in other complexes the proteins assume a single orientation. The binding interface in these complexes consists of a small hydrophobic patch for specificity, surrounded by polar, uncharged residues that may enhance dissociation, and, in most complexes, a ring or patch of charged residues that enhances the association by electrostatic interactions. The entry and exit port of the electrons is located within the hydrophobic interaction site, ensuring rapid electron transfer from one redox centre to the next. Copyright © 2004 John Wiley & Sons, Ltd. [source] [Pt(topy)(Htopy)(ONO2)] complex (Htopy = 2- p -tolylpyridine) and its analogs: 195Pt NMR spectra and fabrication of light-emitting devicesAPPLIED ORGANOMETALLIC CHEMISTRY, Issue 4 2009Hiroto Fukuda Abstract We report fast, high-yield syntheses of a series of [Pt(C,N)(HC,N)X] complexes, where HC,N is 2-phenylpyridine (Hppy) or 2- p -tolylpyridine (Htopy) and X, is Cl,, Br,, I,, ONO2,, NO2, or SCN,. The structure of [Pt(topy)(Htopy)(ONO2)] was analyzed by single-crystal X-ray diffraction. Substitution of Cl, with Br, or I, in our complexes shifted the 195Pt NMR peaks upfield in the order Cl, < Br, < I,, but the magnitudes of their shifts were one-tenth those observed for non-cyclometalated platinum(II) complexes. As the two nitrato complexes showed strong emissions in acetonitrile solution,three to six times those of other complexes,they were used to fabricate OLEDs. Although their emissions were not particularly strong, devices fabricated with platinum(II) complexes containing bulky ligands emitted green light with a short lifetime (,). Copyright © 2009 John Wiley & Sons, Ltd. [source] Intermolecular interactions and molecular geometry in molecular complexes of N,N -dimethylaniline: the 1:1 complex with 1,2,4,5-tetracyanobenzeneACTA CRYSTALLOGRAPHICA SECTION C, Issue 6 2000Tor Dahl The partner molecules of N,N -dimethylaniline,1,2,4,5-tetracyanobenzene (1/1), C8H11N·C10H2N4, are stacked alternately in infinite columns. The N atom of the N,N -dimethylaniline molecule has a partially tetrahedral character and the distance between neighbouring molecules in the stack is relatively short on the side where the lone-pair electrons of this atom are located. Molecular-packing analysis of this and three other complexes of N,N -dimethylaniline shows that there is a close relationship between the strength of the intermolecular interaction on this side and the tetrahedral character of the N atom. [source] Factors affecting human supragingival biofilm composition.JOURNAL OF PERIODONTAL RESEARCH, Issue 4 2009Background and Objective:, Little is known about the factors that affect the microbial composition of supragingival biofilms. This study was designed to examine the relationship between total DNA probe counts of supragingival biofilm samples, clinical parameters and supragingival biofilm composition. Material and Methods:, Supragingival plaque samples were taken from 187 systemically healthy adult subjects (n = 4745 samples). All samples were individually analyzed for their content of 40 bacterial species using checkerboard DNA,DNA hybridization. The relationship between total DNA probe counts and microbial composition was examined by subsetting the data into 10 groups based on 10 percentile increments of the total DNA probe counts. Differences among groups in terms of species counts and proportions were sought, as well as relationships of total plaque DNA probe count and clinical parameters. Results:, There was a wide distribution in mean total DNA probe counts among the 187 subjects. With increasing total plaque levels there was a change in the proportions of individual species and microbial complexes. ,Small plaques' were characterized by high proportions of species in the yellow, orange, purple and ,other' complexes; plaques of moderate mass were characterized by high proportions of Actinomyces and purple complex species, while ,large plaques' exhibited increased proportions of green and orange complex species. Measures of gingival inflammation, pocket depth and recession were significantly positively associated with total DNA probe counts. Increased plaque numbers were related to increased pocket depth irrespective of presence or absence of gingival inflammation. Conclusion:, The proportions of individual species and microbial complexes in supragingival biofilms are influenced by the total numbers of organisms in the biofilm. [source] |