Only Dependent (only + dependent)

Distribution by Scientific Domains


Selected Abstracts


Incontinence in the aged: contact dermatitis and other cutaneous consequences

CONTACT DERMATITIS, Issue 4 2007
Miranda A. Farage
Urinary and faecal incontinence affects a significant portion of the elderly population. The increase in the incidence of incontinence is not only dependent on age but also on the onset of concomitant ageing issues such as infection, polypharmacy, and decreased cognitive function. If incontinence is left untreated, a host of dermatological complications can occur, including incontinence dermatitis, dermatological infections, intertrigo, vulvar folliculitis, and pruritus ani. The presence of chronic incontinence can produce a vicious cycle of skin damage and inflammation because of the loss of cutaneous integrity. Minimizing skin damage caused by incontinence is dependent on successful control of excess hydration, maintenance of proper pH, minimization of interaction between urine and faeces, and prevention of secondary infection. Even though incontinence is common in the aged, it is not an inevitable consequence of ageing but a disorder that can and should be treated. Appropriate clinical management of incontinence can help seniors continue to lead vital active lives as well as avoid the cutaneous sequelae of incontinence. [source]


Dendritic cell activation by danger and antigen-specific T-cell signalling

EXPERIMENTAL DERMATOLOGY, Issue 5 2000
A. D. McLellan
Abstract: Recent transplantation, animal and in vitro studies suggest a dependence of some immune reactions on tissue damage. Although many factors involved in enhancing immune responses through tissue damage have yet to be identified, recent data suggests that one of the targets of these cellular stress factors is the bone marrow derived dendritic cell ( DC). DC are potent initiators of primary immune responses and hold the key to immune reactions through their ability to sense changes in their local environment and respond appropriately to induce T-cell immunity, or possibly tolerance. In the lymph node, DC are also influenced by antigen-specific signalling from T cells, which may extend and amplify DC antigen presenting capabilities, especially for the stimulation of cytotoxic responses. It now appears that both tissue damage and antigen-specific T-cell derived signals act together on the DC to promote the appropriate immune reaction to antigen. Thus DC antigen presenting behaviour is not only dependent on the context of antigen encounter in the periphery, but also on the availability of antigen-specific T cells and their T-cell receptor specificities. [source]


Second-law analysis and optimization of microchannel flows subjected to different thermal boundary conditions

INTERNATIONAL JOURNAL OF ENERGY RESEARCH, Issue 3 2005
Kuan Chen
Abstract Entropy generation and transfer in microchannel flows were calculated and analyzed for different thermal boundary conditions. Due to the small flow cross-sectional area, fluid temperature variation in the lateral direction was neglected and a laterally lumped model was developed and used in the first- and second-law analyses. Since the Peclet numbers of microchannel flows are typically low, heat conduction in the flow direction was taken into consideration. Computed fluid temperature and entropy generation rate were cast into dimensionless forms, thus can be applied to different fluids and channels of different sizes and configurations. Local entropy generation rate was found to be only dependent upon the temperature gradient in the flow direction. The optimization results of microchannel flows exchanging heat with their surroundings indicate the optimal fluid temperature distribution is a linear one. Copyright © 2004 John Wiley & Sons, Ltd. [source]


Solubility, salivary sorption and degree of conversion of dimethacrylate-based polymeric matrixes

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, Issue 2 2008
Luana Gonçalves
Abstract This study investigated the relationship between the solubility, salivary sorption, and degree of conversion of dimethacrylate-based polymeric matrixes. Six polymeric matrixes produced by mixing bis-GMA, TEGDMA and UDMA dimethacrylate monomers were studied. Photoactivation was induced by camphoroquinone/ethyl N,N-dimethyl-4-aminobenzoate. The specimens were light-cured using an irradiance of 850 mW/cm2 for 20 s. The solubility and sorption (,g/mm3) were measured after immersion in artificial saliva (neutral pH) for 7 days. The degree of conversion (%) was obtained by using a FT-IR spectrometer equipped with an attenuated total reflectance crystal (ATR). The degree of conversion varied from 39.15 ± 6.30 to 65.57± 4.80, and was influenced by the viscosity of the monomers present in the polymeric matrixes. The solubility of polymeric matrixes varied between 13.64 ± 0.39 and 25.08 ± 0.83, and was strongly influenced by the degree of conversion (Pearson, r = ,0.9587, p < 0.01). No correlation was found between salivary sorption and the degree of conversion (p = 0.3918). Salivary sorption was only dependent on the chemical and physical structures of the monomers presented in the polymeric matrixes. © 2007 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2008 [source]


Challenges and trends in bioseparations

JOURNAL OF CHEMICAL TECHNOLOGY & BIOTECHNOLOGY, Issue 2 2008
Juan A Asenjo
Abstract In this paper the issues and challenges presented 15 years ago for performing efficient separation processes for recombinant proteins are revised and discussed. Competitive advantage in production was seen as not only dependent on innovations in molecular biology and other areas of basic biological sciences but also on innovation of separations and downstream processes. The trend to develop techniques that exploit fundamental physicochemical principles more efficiently was emphasized, including analysis of the physicochemical properties of proteins and its relation to efficiency in bioseparation. 15 years ago the main thrust was also focused on the development of novel techniques. Clearly the challenges faced today, where highly optimized and efficient production processes exist, are dramatically different. The use of mathematical models for optimizing chromatographic separations and simplifying validation of such operations is extremely advantageous. Their use constitutes an example of how the challenges that bioseparations are facing and will be facing within the next few years can be met. Such models should be extended to a larger number of proteins, chromatographic procedures and experimental conditions. Copyright © 2008 Society of Chemical Industry [source]


Ultrathin polymeric interpenetration network with separation performance approaching ceramic membranes for biofuel

AICHE JOURNAL, Issue 1 2009
Lan Ying Jiang
Abstract Biofuel has emerged as one of the most strategically important sustainable fuel sources. The success of biofuel development is not only dependent on the advances in genetic transformation of biomass into biofuel, but also on the breakthroughs in separation of biofuel from biomass. The "separation" alone currently accounts for 60,80% of the biofuel production cost. Ceramic membranes made of sophisticated processes have shown separation performance far superior to polymeric membranes, but suffers fragility and high fabrication cost. We report the discovery of novel molecular engineering and membrane fabrication that can synergistically produce polymeric membranes exhibiting separation performance approaching ceramic membranes. The newly discovered Polysulfone/Matrimid composite membranes are fabricated by dual-layer coextrusion technology in just one step through phase inversion. An ultrathin dense-selective layer made of an interpenetration network of the two materials with a targeted and stable interstitial space is formed at the interface of two layers for biofuel separation. The combined molecular engineering and membrane fabrication approach may revolutionize future membrane research and development for purification and separation in energy, environment, and pharmaceuticals. © 2008 American Institute of Chemical Engineers AIChE J, 2009 [source]


The foaming of mixtures of albumin and hordein protein hydrolysates in model systems

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, Issue 9 2004
CW Bamforth
Abstract Although hydrolysed albumin and hydrolysed hordein derived from barley are independently capable of stabilising foams in model beer solutions, when both are present together, the net foam stability is less than anticipated. In particular, it seems that hordein, even in an unhydrolysed state, interferes with the ability of albumin-derived polypeptides to stabilise foam. It appears, therefore, that the observed foam stability of a product such as beer is not only dependent on the absolute level of individual foam-stabilising polypeptides but also on the relative proportions of polypeptides derived from the albumin and hordein protein subsets. Copyright © 2004 Society of Chemical Industry [source]


A linear cavity Brillouin fiber laser with multiple wavelengths output

LASER PHYSICS LETTERS, Issue 5 2008
M.R. Shirazi
Abstract A linear cavity Brillouin fiber laser (BFL) is proposed and demonstrated for multi-wavelength operation. The BFL uses a single mode fiber (SMF) as a non-linear gain medium and an optical circulator to generate a linear cavity resonator. Two couplers are used to inject the Brillouin Pump (BP) and tap the BFL output respectively. The effect of the coupler ratio on the BFL performance is studied by keeping constant the ratio of the first coupler and varying the ratio of the second coupler. 11 simultaneous lines with a line spacing of 0.8 nm are obtained at a BP of 11.7 dBm and a coupler ratio of 95:5. The laser output is stable at room temperature with 5 lines obtained at above , 30 dBm, and has the largest signal to noise ratio observed at the remaining lines. The proposed BFL has the advantage of being able to operate at any wavelength and is only dependent on the available BP wavelength. (© 2008 by Astro Ltd., Published exclusively by WILEY-VCH Verlag GmbH & Co. KGaA) [source]


Regularizability Of Linear Descriptor Systems Via Output Plus Partial State Derivative Feedback

ASIAN JOURNAL OF CONTROL, Issue 3 2003
Guang-Ren Duan
ABSTRACT Regularizability of a linear descriptor system via output plus partial state derivative feedback is studied. Necessary and sufficient conditions are obtained, which are only dependent upon the open-loop coefficient matrices. It is also shown that under these necessary and sufficient conditions, "almost all" output plus partial state derivative feedback controllers can regularize a regularizable linear descriptor system. The proposed conditions generalize many existing results. The presented example demonstrates the proposed results. [source]