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One Representative (one + representative)

Distribution by Scientific Domains
Life Sciences50%
Humanities and Social Sciences50%

Selected Abstracts

Plasmodium falciparum myosins: Transcription and translation during asexual parasite development,

CYTOSKELETON, Issue 4 2005
Jacqueline Chaparro-Olaya
Abstract Six myosins genes are now annotated in the Plasmodium falciparum Genome Project. Malaria myosins have been named alphabetically; accordingly, we refer to the two latest additions as Pfmyo-E and Pfmyo-F. Both new myosins contain regions characteristic of the functional motor domain of "true" myosins and, unusually for P. falciparum myosins, Pfmyo-F encodes two consensus IQ light chain-binding motifs. Phylogenetic analysis of the 17 currently known apicomplexan myosins together with one representative of each myosin class clusters all but one of the apicomplexan sequences together in Class XIV. This refines the earlier definition of the Class XIV Subclasses XIVa and XIVb. RT-PCR on blood stage parasite mRNA amplifies a specific product for all six myosins and each shows developmentally regulated transcription. Thus: Pfmyo-A and Pfmyo-B genes are transcribed throughout development; Pfmyo-C is predominant in trophozoites; Pfmyo-D occurs in trophozoites and schizonts; Pfmyo-E though barely present in earlier stages is abundant in schizonts; Pfmyo-F increases steadily throughout development and maturation. It is known that Pfmyo-A and Pfmyo-B are synthesised during late schizogony and we now show that Pfmyo-D expression is also temporally regulated to late trophozoites and schizonts where it distributes close to segregating nuclei. Thus, in asexual stages myosin synthesis does not always parallel transcript accumulation, showing that translation is also regulated. The implication is that the mRNAs are either subjected to turnover, synthesised and degraded, or that they are sequestered in an inactivate form until required for protein synthesis. Cell Motil. Cytoskeleton 60:200,213, 2005. © 2005 Wiley-Liss, Inc. [source]

Text and image in celtiberia: the adoption and adaptation of written language into indigenous visual vocabulary

OXFORD JOURNAL OF ARCHAEOLOGY, Issue 2 2003
FIONA A. ROSE
SummaryThis study is concerned with the relationships between text and image in central Spain during the period second century BC,second century AD. Three discrete relationships are isolated, each one representative of a unique strategy for communicating with both written and figured language. The paper argues that the Celtiberian populi adopted Roman epigraphic practice into a pre-existing visual vocabulary, reconfiguring written communication into an indigenous framework that met local predilections. [source]

"Perpetual Peace": A Project by Europeans for Europeans?

PEACE & CHANGE, Issue 3 2008
ref Aksu
Immanuel Kant's classic essay Perpetual Peace has famously informed much of the neoliberal "democratic peace" scholarship in International Relations over the past few decades. It has also influenced contemporary notions of cosmopolitanism and global governance. We need to realize, however, that Kant's essay is only one representative of the eighteenth-century European thought on perpetual peace. Several other writers have produced their own versions of the perpetual peace ideal. This article surveys some notable eighteenth-century perpetual peace proposals from a specific perspective: it seeks to find out the attitude of these various proposals toward non-European peoples. It asks, in other words, whether and to what extent non-Europeans were "included" in the eighteenth-century European visions of a perpetual peace. [source]

A new member of the Arabidopsis WRKY transcription factor family, AtWRKY6, is associated with both senescence- and defence-related processes

THE PLANT JOURNAL, Issue 2 2001
Silke Robatzek
Summary WRKY proteins constitute a large family of plant-specific transcription factors whose precise functions have yet to be elucidated. Here we show that expression of one representative in Arabidopsis, AtWRKY6, is influenced by several external and internal signals often involved in triggering senescence processes and plant defence responses. Progressive 5, deletions of the AtWRKY6 promoter allowed separation of defined regions responsible for the expression in distinct organs or upon pathogen challenge. Nuclear localization of AtWRKY6 was demonstrated; protein truncations and gain-of-function studies enabled delineation of a region harbouring a novel type of functional nuclear localization signal (NLS). [source]