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One Culture (one + culture)
Selected AbstractsImproved detection of chromosomal abnormalities in chronic lymphocytic leukemia by conventional cytogenetics using CpG oligonucleotide and interleukin-2 stimulation: A Belgian multicentric study,GENES, CHROMOSOMES AND CANCER, Issue 10 2009Natalie Put We performed a multicentric study to assess the impact of two different culture procedures on the detection of chromosomal abnormalities in 217 consecutive unselected cases with chronic lymphocytic leukemia (CLL) referred for routine analysis either at the time of diagnosis (n = 172) or during disease evolution (n = 45). Parallel cultures of peripheral blood or bone marrow were set up with the addition of either the conventional B-cell mitogen 12- O -tetradecanoyl-phorbol-13-acetate (TPA) or a combination of CpG oligonucleotide (CpG) and interleukin-2 (IL-2). Cytogenetic analyses were performed on both cultures. Clonal abnormalities were identified in 116 cases (53%). In 78 cases (36%), the aberrant clone was detected in both cultures. Among these, the percentages of aberrant metaphases were similar in both conditions in 17 cases, higher in the CpG/IL-2 culture in 43 cases, and higher in the TPA culture in 18 cases. Clonal aberrations were detected in only one culture, either in CpG/IL-2 or TPA in 33 (15%) and 5 (2%) cases, respectively. Taken together, abnormal karyotypes were observed in 51% with CpG/IL-2 and 38% with TPA (P < 0.0001). Application of FISH (n = 201) allowed the detection of abnormalities not visible by conventional cytogenetic analysis in 80 cases: del(13q) (n = 71), del(11q) (n = 5), +12 (n = 2), del(14q) (n = 1), and del(17p) (n = 1). In conclusion, our results confirm that CpG/IL-2 stimulation increases the detection rate of chromosomal abnormalities in CLL compared with TPA and that further improvement can be obtained by FISH. However, neither conventional cytogenetics nor FISH detected all aberrations, demonstrating the complementary nature of these techniques. © 2009 Wiley-Liss, Inc. [source] Study abroad as a process of learning intercultural competence in nursingINTERNATIONAL JOURNAL OF NURSING PRACTICE, Issue 3 2004Liisa Koskinen RN PhD The aim of this research was to describe an international student exchange programme as a context of learning intercultural competence in nursing. Twelve Finnish nursing students who had participated in an exchange programme in the United Kingdom participated. The data consisted of group interviews, learning documents, background questionnaires and research diary notes, and the method of inductive content analysis was used. Study abroad as a process of learning intercultural competence consisted of three ethno-categories: transition from one culture to another, adjustment to the difference and gaining intercultural sensitivity. The exchange programme as a context of learning intercultural competence was characterized by a problematic orientation phase, a study abroad phase that involved stressful but rewarding adjustment to the intercultural differences and an inadequate re-entry debriefing phase. In order for the international experience of nursing students to have an impact on their understanding of diversity, they need assistance in each phase of the programme. Particularly, the students need intercultural tutoring and mentoring to venture into encounters with local people, including direct client contacts, during their study abroad. [source] Intervening in Employee Disputes: How and When Will Managers from China, Japan and the USA Act Differently?MANAGEMENT AND ORGANIZATION REVIEW, Issue 2 2007Jeanne M. Brett abstract We investigated how third party managers from China, Japan and the USA intervened in employees' disputes. Consistent with predictions, we found (using non-linear HLM analysis) that managers who were superiors to the disputants behaved autocratically and/or decided on conservative (e.g., contract adhering) outcomes; but managers who were peers (especially in China and the USA), generally involved disputants in decision-making and obtained integrative outcomes that went beyond initial contract related mandates. Our results extend prior research and theorizing using the dispositional and constructivist perspectives on culture by introducing norm complexity as an explanation for variations in third party conflict intervention behaviour within one culture. [source] Does professional and public opinion in child abuse differ?CHILD ABUSE REVIEW, Issue 6 2002An issue of cross-cultural policy implementation Abstract There are cultural variations in childcare and socialisation practices, and actions considered abuse in one culture may be acceptable in others. The extent to which children's rights are regarded as such within their own cultures as well as by governments may vary greatly. Moreover, there is a tendency for the public to make allowances for the intentions and circumstances of child abusers, at least in less severe or obvious cases or where the actions in question are socially sanctioned. However, there are also many professions involved in prevention or remediation of child abuse, or in the implementation of policies on children generally. Medicine, law, education and the social services are especially relevant here. Professionals in these areas could be expected by virtue of their training and experience to bring to their grasp of abuse issues a dimension that transcends cultural variation. Evidence from the literature and from two Singapore studies is used to explore the possibility that many professionals may retain attitudes to child maltreatment that reflect their culture rather than any transcultural agreement on children's rights generally or child abuse specifically. If true, changing professional attitudes should be an important priority. Copyright © 2002 John Wiley & Sons, Ltd. [source] | ||||||||||