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Older Sisters (older + sister)
Selected AbstractsCerebral palsy in siblings caused by compound heterozygous mutations in the gene encoding protein CDEVELOPMENTAL MEDICINE & CHILD NEUROLOGY, Issue 5 2010CHOONG YI FONG We report two sisters with extensive bilateral periventricular haemorrhagic infarction (PVHI) causing cerebral palsy (CP). The older sister presented at 20 months with cortical visual blindness, spastic diplegia, and purpura fulminans. The younger sister presented aged 3 days old with apnoeas and multifocal seizures. She subsequently had global developmental delay, cortical visual blindness, spastic quadriplegia, epilepsy, and purpura fulminans at age 2 years. Neuroimaging of both siblings showed bilateral PVHI consistent with bilateral cerebral intramedullary venous thrombosis occurring at under 28 weeks' gestation for the older sister and around time of birth for the younger sister. At latest follow-up, the older sister (13y) has spastic diplegia at Gross Motor Function Classification System (GMFCS) level II, and the younger sister (10y) has spastic quadriplegia at GMFCS level IV. Both sisters showed partial quantitative reduction in plasma protein C antigen and severe qualitative reduction in plasma protein C anticoagulant activity. They were heterozygous for two independent mutations in the protein C gene (PROC). There was no other risk factor for CP. To our knowledge, this is the first family reported with compound heterozygous PROC mutations as the likely genetic cause of familial CP. This report adds to the list of known monogenic causes of CP. [source] Extremely preterm infants tolerate skin-to-skin contact during the first weeks of lifeACTA PAEDIATRICA, Issue 8 2010Ragnhild Maastrup Abstract Aim:, To determine if clinically stable extremely preterm infants can maintain their temperature during skin-to-skin contact and to screen for other negative effects. Methods:, Continuous measurement of 22 stable infants' physical parameters 2 h before, during, and 2 h after skin-to-skin-contact. Mean gestational age at birth was 25 weeks and 4 days, mean post-natal age was 8 days, postmenstrual age was 26 weeks and 6 days, and mean actual weight 702 g. Mean duration of skin-to-skin-contact was 98 min. 16 infants were skin-to-skin with the mother, five with the father and one with an older sister. Results:, There were no significant differences in mean skin temperature, heart rate, respiration rate, or oxygen saturation before, during, and after skin-to-skin contact. While staying within normal range, the mean skin temperature increased 0.1°C during skin-to-skin contact with the mother and decreased 0.3°C during skin-to-skin contact with the father (p = 0.011) (without post-hoc correction). Conclusion:, Clinically stable, extremely preterm infants can keep adequate skin temperature and adequate physical stability during skin-to-skin contact with their parents. [source] Temperament and the Quality of Best Friendships: Effect of Same-Sex Sibling Relationships,FAMILY RELATIONS, Issue 3 2002J. Kelly McCoy The authors examined whether early adolescents' sibling relationships ameliorate the effects of a difficult temperament on best friendships, exploring whether qualities of early adolescents' sibling relationships would moderate the link between temperamental difficulties and best friendship quality. Data were collected at two points. At first collection, parents provided temperament ratings for 73 later-born siblings (M= 7 years). Five years later, adolescents provided information about support and discord present in their best friendships and older siblings provided information about the warmth and conflict in their same-sex sibling dyads. The hypothesized moderating effect of the sibling relationship was found only for early adolescent girls. Support and discord in girls' best friendships was negatively and positively predicted, respectively, by level of temperamental difficulty only when relationships with their older sisters were lower in warmth or higher in conflict. Implications for understanding and improving early adolescents' closest friendships are discussed. [source] Kin influence on the decision to start using modern contraception: A longitudinal study from rural GambiaAMERICAN JOURNAL OF HUMAN BIOLOGY, Issue 4 2009Ruth Mace In earlier work in rural Gambia, we found that kin influence reproductive success: matrilineal kin, especially mothers, maternal grandmothers and unmarried older sisters all helped to promote the survival and nutrition of young children; in contrast patrilineal kin, especially husband's mother, promoted fertility. These differing influences of maternal and paternal lineage are predicted on the basis of kin selection and sexual conflict theory, because the costs of reproduction fall more heavily on the mother than the father. These studies covered the period 1950,1975, when this population was essentially "natural fertility, natural mortality." It is not possible to tell whether these effects were due to kin influencing active reproductive decision-making, or due to indirect effects such as kin improving nutrition by helping. Since 1976, modern contraception has become available in this community. In an analysis of the behavioral ecology of the decision to start using modern contraception, we found that high parity for your age was a key determinant of the decision, as was village and calendar year. Here, we examine whether the presence or absence of kin and also whether the contraceptive status of kin influenced the decision to start using contraception. We find little evidence that kin directly influence contraceptive uptake, either by their presence/absence or as models for social learning. However, death of a first husband (i.e., widowhood) does accelerate contraceptive uptake. We discuss our results from an evolutionary demography perspective, in particular regarding theories of sexual conflict, biased cultural transmission, and social learning. Am. J. Hum. Biol., 2009. © 2009 Wiley-Liss, Inc. [source] Birth order and sibling sex ratio in homosexual transsexual South Korean men: Effects of the male-preference stopping rulePSYCHIATRY AND CLINICAL NEUROSCIENCES, Issue 5 2007KENNETH J. ZUCKER phd Abstract Two biodemographic variables , birth order and sibling sex ratio , have been examined in several Western samples of homosexual transsexual men. The results have consistently shown that homosexual transsexuals have a later birth order and come from sibships with an excess of brothers to sisters; the excess of brothers has been largely driven by the number of older brothers and hence has been termed the fraternal birth order effect. In the present study the birth order and sibling sex ratio were examined in an Asian sample of 43 homosexual transsexual men and 49 heterosexual control men from South Korea. Although the transsexual men had a significantly late birth order, so did the control men. Unlike Western samples, the Korean transsexuals had a significant excess of sisters, not brothers, as did the control men, and this was largely accounted for by older sisters. It is concluded that a male-preference stopping rule governing parental reproductive behavior had a strong impact on these two biodemographic variables. Future studies that examine birth order and sibling sex ratio in non-Western samples of transsexuals need to be vigilant for the influential role of stopping rules, including the one identified in the present study. [source] | ||||||||||