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Old Friends (old + friend)
Selected AbstractsSpironolactone: An Old Friend RediscoveredJOURNAL OF CLINICAL HYPERTENSION, Issue 7 2006Domenic A. Sica MD No abstract is available for this article. [source] Death Is a Crafty Old FriendJOURNAL OF HOSPITAL MEDICINE, Issue 6 2008Randy J. Ferrance DC [source] The gut, immunoregulation and micro-organisms from man's evolutionary pastNUTRITION BULLETIN, Issue 2 2010G. A. W. Rook Summary Man has moved rapidly from the hunter-gatherer environment to the living conditions of the rich industrialised countries. The hygiene hypothesis suggests that the resulting changed and reduced pattern of exposure to certain critical micro-organisms, mostly derived from mud, animals and faeces, has led to disordered regulation of the immune system and, hence, to increases in chronic inflammatory disorders such as allergies, inflammatory bowel diseases and autoimmunity. Epidemiology, backed up by laboratory models, indicates that the relevant organisms are those that have very long associations with the mammalian immune system, traceable back to the Palaeolithic or earlier. Often, these organisms have been present as commensals (notably in the intestinal microbiota), environmental ,pseudocommensals', sub-clinical infections or asymptomatic carrier states, and the mammalian immune system is in a state of ,evolved dependence' on their continued presence. Several of these ,Old Friends', often operating primarily in the gut, act as modulators of dendritic cells and T cells, leading to the establishment of immunoregulatory circuits. Clinical trials are in progress to test living helminths (Trichuris suis and Necator americanus) in allergies, inflammatory bowel disease and multiple sclerosis. We can anticipate rapid increases in the use of these and other organisms or their components in novel types of therapy with applications in several branches of medicine. Probiotics tested in clinical trials targeting chronic inflammatory disorders have so far given unconvincing results, but if strains for these indications are selected on the basis of their ability to induce immunoregulation, and not merely imposed by companies that have intellectual property rights, we can anticipate rapid progress. [source] Minaret Ban Is a Blow for ToleranceNEW PERSPECTIVES QUARTERLY, Issue 2 2010AYAAN HIRSI ALI To the shock of the world, the mild-mannered Swiss have acted the most radically of any European country out of fear of Muslim immigrants by banning minarets. Was this a blow against tolerance, or for it? Is Islam a European religion, or is Europe a Christian club? Meanwhile, as Turkey becomes more confident in its regional power and Muslim identity it is shaking up some old friends. In this section, two of Europe's most prominent Muslim voices, the foreign minister of Sweden and a top Turkish official try to sort it out. [source] Islam Is a European ReligionNEW PERSPECTIVES QUARTERLY, Issue 2 2010TARIQ RAMADAN To the shock of the world, the mild-mannered Swiss have acted the most radically of any European country out of fear of Muslim immigrants by banning minarets. Was this a blow against tolerance, or for it? Is Islam a European religion, or is Europe a Christian club? Meanwhile, as Turkey becomes more confident in its regional power and Muslim identity it is shaking up some old friends. In this section, two of Europe's most prominent Muslim voices, the foreign minister of Sweden and a top Turkish official try to sort it out. [source] Europe 3.0,Bring Turkey InNEW PERSPECTIVES QUARTERLY, Issue 2 2010CARL BILDT To the shock of the world, the mild-mannered Swiss have acted the most radically of any European country out of fear of Muslim immigrants by banning minarets. Was this a blow against tolerance, or for it? Is Islam a European religion, or is Europe a Christian club? Meanwhile, as Turkey becomes more confident in its regional power and Muslim identity it is shaking up some old friends. In this section, two of Europe's most prominent Muslim voices, the foreign minister of Sweden and a top Turkish official try to sort it out. [source] Social networking: Communication revolution or evolution?BELL LABS TECHNICAL JOURNAL, Issue 2 2008Cheryl L. Coyle Social networks and the need to communicate are universal human conditions. A general assumption is that communication technologies help to increase and strengthen social ties. The Internet provides many social networking opportunities. But how do social networking sites affect individual relationships? Do people use social networking sites to expand their personal networks, to find people who have had similar experiences, to discuss a common hobby, for the potential of offline dating? Or, do people spend time on networking sites to deepen their existing personal networks and stay connected to old friends or distant family? What is the nature of the communications that transpire on social networking sites? Is it personal, emotional, private, and important; or trivial, informal, and public? We examined the literature on social networking sites and conducted our own studies of how students on American college campuses engage in social networking. © 2008 Alcatel-Lucent. [source] | ||||||||||