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Old Female (old + female)
Terms modified by Old Female Selected AbstractsAn unusual cause of dizziness in bulimia nervosa: A case reportINTERNATIONAL JOURNAL OF EATING DISORDERS, Issue 4 2005Randy A. Sansone MD Abstract Objective The current article describes the case of a 23<->year<->old female with purging<->type bulimia nervosa who was evaluated by her primary care physician for dizziness and lightheadedness. Methods After laboratory studies were performed by her primary care physician, the patient was admitted to the hospital because of severe anemia. The patient had been taking nonsteroidal antiinflammatory drugs <(>NSAIDS<)> at prescribed doses for shin splints that were secondary to jogging and developed gastric erosion. Results Endoscopic examination showed that she had diffuse gastritis with linear, streaky ulcerations throughout the body of the stomach. Discussion Lightheadedness is a common clinical symptom among individuals with eating disorders, but is typically related to dehydration, malnutrition, hypometabolism, andor combinations of these factors. Clinicians need to consider NSAID use, which may cause erosive gastritis, blood loss, and lightheadedness. © 2005 by Wiley Periodicals, Inc. [source] Cutaneous Congenital Plexiform Cellular Schwannoma: A Simulant of Malignant Peripheral Nerve Sheath Tumor of Childhood , A Case Report and Literature ReviewJOURNAL OF CUTANEOUS PATHOLOGY, Issue 1 2005M. Matthews Cutaneous plexiform schwannoma is a rare multilobulated variant of benign schwannoma. When presenting as the cellular subtype with significantly increased proliferative rate, diagnostic consideration of a malignant peripheral nerve sheath tumor is prompted. However, follow up demonstrates a benign natural history with propensity for local recurrence and typical lack of association with neurocutaneous syndromes. These lesions most commonly occur as cutaneous and subcutaneous masses of the extremities in the first four decades. Only 9 cases of congenital tumors are reported. A case of congenital plexiform cellular schwannoma, presenting as a cutaneous mass measuring 3.5 × 2.5 × 2.0 cm, excised from the left upper arm of a 16 month old female is discussed. Regions of increased cellularity and proliferation co-localized and were unassociated with nuclear anaplasia. Mitotic figures numbered 7 per 10 400x fields. The tumor cells were strongly immunoreactive for S-100 protein. The MIB-1index was multifocally 25% and p53 protein over expression was present in 50% of nuclei. Following excision with free margins the tumor locally recurred after 16 months. The recurrence was morphologically identical to the original lesion. Recognition of the clinical and morphological characteristics of this rarely encountered benign neoplasm will facilitate in diagnosing this entity. [source] Successful treatment of early detected trilateral retinoblastoma using standard infant brain tumor therapy,PEDIATRIC BLOOD & CANCER, Issue 3 2010Karen D. Wright MD Abstract Trilateral retinoblastoma is characterized by the presence of retinoblastoma with an intracranial tumor. The incidence is low and prognosis poor. Due to the paucity of information regarding successful treatment, we report the case of a 6 month old female referred for leukocoria and found to have an associated suprasellar tumor and pineal enhancement. The patient, treated with standard infant brain tumor therapy, remains alive without signs of active disease 35 months after diagnosis; no surgery or irradiation was used. Early diagnosis of trilateral retinoblastoma may facilitate the use of less intensive therapeutic approaches and result in excellent outcomes in these patients. Pediatr Blood Cancer. 2010;55:570,572. © 2010 Wiley-Liss, Inc. [source] Parental mosaic trisomy 21 detected following maternal cell contamination of an amniotic fluid specimen from a normal male pregnancyPRENATAL DIAGNOSIS, Issue 9 2007Melissa L. Street Abstract We report a case of maternal mosaic trisomy 21 ascertained at prenatal diagnosis as a result of maternal cell contamination of an amniotic fluid sample. A 34 year old female was referred for karyotyping because of a previous trisomy 21 pregnancy. Chromosome analysis of primary in situ cultures showed a karyotype of 47,XX, + 21[6]/46,XY[32]/46,XX[2]. Molecular testing demonstrated maternal cell contamination of the amniotic fluid sample and G-banded karyotyping of maternal blood showed that 3/200 cells had trisomy 21, consistent with the mother being a Down syndrome mosaic. A normal male baby with a 46,XY chromosome complement was delivered at 30 weeks. This case emphasises the need for close collaboration between cytogenetic and molecular genetics laboratories in resolving unusual cases of mosaicism. Copyright © 2007 John Wiley & Sons, Ltd. [source] Metachronous bilateral primary low-grade mucosa-associated lymphoid tissue non-Hodgkins lymphoma of the breastASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, Issue 3 2009M Helene YILMAZ Abstract We report the rare occurrence of bilateral low-grade MALT lymphoma of the breast in a 73 year old female. The clinical, pathological and treatment details are discussed, with a review of the literature. [source] Bilateral acute angle closure glaucoma in a 50 year old female after oral administration of flavoxateBRITISH JOURNAL OF CLINICAL PHARMACOLOGY, Issue 5 2008Zakir Shaik Mohammed No abstract is available for this article. [source] 4367: Intravitreal injection of anti-VEGF and diagnosis of primary intraocular-central nervous system lymphomaACTA OPHTHALMOLOGICA, Issue 2010J GAMBRELLE Purpose We report the case of the diagnosis of primary intraocular- central nervous system (CNS) lymphoma in a patient treated by anti-VEGF. Methods An 88-year old female, with a medical history of bilateral ARMD treated by intravitreal injections of ranibizumab for 1 year, was referred to our department for bilateral vitritis diagnosed 10 days after the last anti-VEGF injection. A complete vitritis work-up including aqueous humour analysis, magnetic resonance imaging of the brain and vitreous biopsy enabled us to confirm the diagnosis of primary intraocular-CNS lymphoma. Results To the best of our knowledge, this is the first report of the diagnosis of primary intraocular-CNS lymphoma in a patient treated by anti-VEGF for ARMD. In our opinion, the occurrence of lymphoma in this case was coincidental and not due to the anti-VEGF injections. The differential diagnosis of vitritis in elderly patients is relatively large. Endophthalmitis or uveitis has been described after anti-VEGF injections. In such a situation, there is actually a risk of overlooking a diagnosis of intraocular lymphoma in the mistaken belief that the observed vitritis may be a reaction to administred anti-VEGFs. If no direct time-relationship with the anti-VEGF injections can be found, a classic vitritis work-up should be performed. Anti-VEGF treatment did not impede cytological diagnosis in our patient. Conclusion Although in some none-CNS non-Hodgkin lymphomas (NHL) systemic anti-VEGF therapy is added to chemotherapy schedules, the use of anti-VEGF did not halt the spread of the lesion within the eye in this case. It can, therefore, be presumed that local anti-VEGF therapy has no adjuvant effect in primary intraocular lymphoma. [source] Age-dependent effect of prenatal stress on hippocampal cell proliferation in female ratsEUROPEAN JOURNAL OF NEUROSCIENCE, Issue 3 2009Muriel Koehl Abstract Stressors occurring during pregnancy can alter the developmental trajectory of offspring and lead to, among other deleterious effects, cognitive deficits and hyperactivity of the hypothalamo-pituitary-adrenal axis. A recent feature of the prenatal stress (PS) model is its reported influence on structural plasticity in hippocampal formation, which sustains both cognitive functions and stress responsiveness. Indeed, we and others have previously reported that males exposed to stress in utero are characterized by a decrease in hippocampal cell proliferation, and consequently neurogenesis, from adolescence to senescence. Recent studies in females submitted to PS have reported conflicting results, ranging from no effect to a decrease in cell proliferation. We hypothesized that changes in cell proliferation in PS female rats are age dependent. To address this issue, we examined the impact of PS on hippocampal cell proliferation in juvenile, young, middle-aged and old females. As hypothesized, we found an age-dependent effect of PS in female rats as cell proliferation was significantly decreased only when animals reached senescence, a time when adrenal gland weight also increased. These data suggest that the deleterious effects of PS on hippocampal cell proliferation in females are either specific to senescence or masked during adulthood by protective factors. [source] Generation of pluripotent stem cells from eggs of aging miceAGING CELL, Issue 2 2010Junjiu Huang Summary Oocytes can reprogram genomes to form embryonic stem (ES) cells. Although ES cells largely escape senescence, oocytes themselves do senesce in the ovaries of most mammals. It remains to be determined whether ES cells can be established using eggs from old females, which exhibit reproductive senescence. We attempted to produce pluripotent stem cell lines from artificial activation of eggs (also called pES) from reproductive aged mice, to determine whether maternal aging affects pES cell production and pluripotency. We show that pES cell lines were generated with high efficiency from reproductive aged (old) mice, although parthenogenetic embryos from these mice produced fewer ES clones by initial two passages. Further, pES cell lines generated from old mice showed telomere length, expression of pluripotency molecular markers (Oct4, Nanog, SSEA1), alkaline phosphatase activity, teratoma formation and chimera production similar to young mice. Notably, DNA damage was reduced in pES cells from old mice compared to their progenitor parthenogenetic blastocysts, and did not differ from that of pES cells from young mice. Also, global gene expression differed only minimally between pES cells from young and old mice, in contrast to marked differences in gene expression in eggs from young and old mice. These data demonstrate that eggs from old mice can generate pluripotent stem cells, and suggest that the isolation and in vitro culture of ES cells must select cells with high levels of DNA and telomere integrity, and/or with capacity to repair DNA and telomeres. [source] Lifetime sexual dimorphism in Juniperus communis var. communisPLANT SPECIES BIOLOGY, Issue 1 2007LENA K. WARD Abstract The sexes of dioecious Juniperus communis were differentially affected over their lifetime in response to ecological and physiological stress in populations of different ages studied over 23 years in southern England. In a young population, the female survival rate was less than the male rate, with more females dying during a severe attack by rabbits and later with fungus disease in the roots. The sex ratio (female : male) in marked individuals was predicted by age, changing from 1:1.13 in 1983 to 1:1.32 in 2005. In an old senescing population, where two-thirds of the individuals died, the sex ratio varied, but overall became more male biased (1:1.51,1:2.10). Males had a greater resistance to terminal disease, and were slightly older than females at death (110 years compared to 106). Young females grew less than males, presumably because of greater trade-offs with reproductive effort: the mean annual shoot growth was 6.7 cm compared to 8.1 cm in males. By approximately 30 years of age, heights of the sexes were significantly different. The annual growth of old females (4.8 cm) was greater than that in males (4.3 cm), possibly because males survived longer in poor health. Sexual differences in height in the old population were progressively lost. Cone abundance in females was less than that in males and cone production had greater periodicity; the young population outperformed the old. There were slightly longer time lags in inverse correlations between growth and reproductive indices in females. [source] | |||||||||||||