Old

Distribution by Scientific Domains
Distribution within Medical Sciences

Kinds of Old

  • d old
  • day old
  • days old
  • h old
  • hour old
  • month old
  • oldest old
  • very old
  • week old
  • y old
  • year old

  • Terms modified by Old

  • old adult
  • old age
  • old age groups
  • old age psychiatry
  • old animals
  • old argument
  • old bone
  • old boy
  • old cell
  • old child
  • old disease
  • old dog new trick
  • old drug
  • old female
  • old female patient
  • old field
  • old forest
  • old friend
  • old girl
  • old group
  • old groups
  • old growth
  • old idea
  • old individual
  • old infant
  • old leaf
  • old male
  • old man
  • old molecule
  • old mouse
  • old myocardial infarction
  • old ones
  • old patient
  • old people
  • old plant
  • old pole
  • old population
  • old presenting
  • old problem
  • old question
  • old rat
  • old red sandstone
  • old site
  • old stand
  • old story
  • old subject
  • old testament
  • old way
  • old wine
  • old woman
  • old world
  • old world cutaneous leishmaniasis
  • old world monkey
  • old world primate
  • old yellow enzyme

  • Selected Abstracts


    FETAL ALCOHOL SYNDROME: SAME OLD, SAME OLD

    ADDICTION, Issue 8 2009
    ERNEST L. ABEL
    No abstract is available for this article. [source]


    LINEAGES WITH LONG DURATIONS ARE OLD AND MORPHOLOGICALLY AVERAGE: AN ANALYSIS USING MULTIPLE DATASETS

    EVOLUTION, Issue 4 2007
    Lee Hsiang Liow
    Lineage persistence is as central to biology as evolutionary change. Important questions regarding persistence include: why do some lineages outlive their relatives, neither becoming extinct nor evolving into separate lineages? Do these long-duration lineages have distinctive ecological or morphological traits that correlate with their geologic durations and potentially aid their survival? In this paper, I test the hypothesis that lineages (species and higher taxa) with longer geologic durations have morphologies that are more average than expected by chance alone. I evaluate this hypothesis for both individual lineages with longer durations and groups of lineages with longer durations, using more than 60 published datasets of animals with adequate fossil records. Analyses presented here show that groups of lineages with longer durations fall empirically into one of three theoretically possible scenarios, namely: (1) the morphology of groups of longer duration lineages is closer to the grand average of their inclusive group, that is, their relative morphological distance is smaller than expected by chance alone, when compared with rarified samples of their shorter duration relatives (a negative group morpho-duration distribution); (2) the relative morphological distance of groups of longer duration lineages is no different from rarified samples of their shorter duration relatives (a null group morpho-duration distribution); and (3) the relative morphological distance of groups of longer duration lineages is greater than expected when compared with rarified samples of their shorter duration relatives (a positive group morpho-duration distribution). Datasets exhibiting negative group morpho-duration distributions predominate. However, lineages with higher ranks in the Linnean hierarchy demonstrate positive morpho-duration distributions more frequently. The relative morphological distance of individual longer duration lineages is no different from that of rarified samples of their shorter duration relatives (a null individual morpho-duration distribution) for the majority of datasets studied. Contrary to the common idea that very persistent lineages are special or unique in some significant way, both the results from analyses of long-duration lineages as groups and individuals show that they are morphologically average. Persistent lineages often arise early in a group's history, even though there is no prior expectation for this tendency in datasets of extinct groups. The implications of these results for diversification histories and niche preemption are discussed. [source]


    THE CHANGING STRUCTURE OF THE CENTRAL PLACE SYSTEM IN TRØNDELAG, NORWAY, OVER THE PAST 40 YEARS , VIEWED IN THE LIGHT OF OLD AND RECENT THEORIES AND TRENDS

    GEOGRAFISKA ANNALER SERIES B: HUMAN GEOGRAPHY, Issue 2007
    Britt Dale
    ABSTRACT. The IGU Symposium on Urban Geography in Lund in 1960 was a path-breaking event towards new nomothetic thinking within the discipline. In nearly half of the papers, the state of the art in central place research was presented and debated. The symposium was the main source of inspiration for a study of the central place system in Midt-Norge in the 1960s, a research project that has been followed up in stages over a 40-year period. The result is a unique collection of data, covering all central places in the region and the location of approximately 200 service functions of different categories in the 1960s, 1980s and c. 2000. Despite the profound changes that have taken place on the part of the consumer, as well as the supplier, the main structure of the central place hierarchy has been surprisingly stable. However, when looking at the growth and decline of each of the different service functions, considerable dynamics have been found. There are tendencies of centralization/concentration as well as decentralization/dispersion. Furthermore, the functional division of labour by vertical steps and tiers in the 1960s has been supplemented by horizontal specialization between places, and also in the lower levels of the central place hierarchy. In this paper, we present and discuss some of the main changes that have taken place in the system in the light of older and newer theories and trends. [source]


    OPEN MESH-PLUG INGUINAL HERNIA REPAIR IN THE OLDEST OLD

    JOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 8 2009
    Theodoros E. Pavlidis MD
    No abstract is available for this article. [source]


    THE OLDEST OLD WITH HYPERTENSION: TREAT OR NOT TREAT?

    JOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 1 2007
    Huai Yong Cheng MD
    No abstract is available for this article. [source]


    ANGST IN SHANGRI-LA: JAPANESE FEAR OF GROWING OLD

    JOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 9 2005
    Yumiko Arai MD
    No abstract is available for this article. [source]


    INTRODUCTION: REHEARSING THE OLD AND ANTICIPATING THE NEW

    JOURNAL OF CHINESE PHILOSOPHY, Issue 2009
    ON-CHO NG
    [source]


    Pulmonary function in long-term survivors of pediatric hematopoietic cell transplantation

    PEDIATRIC BLOOD & CANCER, Issue 5 2006
    Paul A. Hoffmeister MPH
    Abstract Background The purpose of this study was to determine the prevalence of pulmonary dysfunction in pediatric hematopoietic cell transplant (HCT) survivors and to identify associated risk factors. Procedure In a cross-sectional study, patients surviving at least 5 years after pediatric HCT were requested to undergo pulmonary function testing (PFT). Risk factors for restrictive lung disease (RLD) and obstructive lung disease (OLD) were analyzed using multivariate analysis. Results Among 472 patients contacted, 260 (55%) participated and 215 were selected for analysis. These patients were transplanted at a median age of 8.3 (0.3,18.0) years; 175 for hematologic malignancies and 40 for non-malignant diseases. The preparative regimens for 133 patients included fractionated TBI (FTBI), 29 single-fraction TBI (SFTBI), and 53 non-TBI regimens. PFT was performed at a median of 10 (5.0,27.5) years after HCT. Forty percent of patients had either RLD or OLD (28% RLD, 9% OLD, 3% mixed RLD/OLD) and at least 15% had an isolated low-DLCO. Moderate-to-severe impairment was present in 45% of patients with RLD or OLD. In multivariate analysis, risk factors associated with RLD included transplant regimen, transplant diagnosis, scleroderma/contracture, and donor relation. Patients treated with SFTBI had the highest risk of RLD. Risk factors for OLD included chronic graft-versus-host disease, transplant regimen, and time after HCT. Patients surviving 20 or more years after HCT had the highest risk of OLD. Conclusions Fifty-five percent of long-term pediatric HCT survivors had pulmonary dysfunction. These findings stress the need for long-term follow-up to detect pulmonary dysfunction. Pediatr Blood Cancer 2006; 47:594,606. © 2005 Wiley-Liss, Inc. [source]


    Classic and false memory designs: An electrophysiological comparison

    PSYCHOPHYSIOLOGY, Issue 5 2004
    Doreen Nessler
    Abstract In false memory tasks new items either overlap with the semantic concepts of studied items (LURE) or do not (NEW). ERP differences between OLD and NEW items in false memory tasks have been interpreted as similar to episodic memory effects observed in classic recognition studies. However, NEW items in a false memory task can be rejected on the basis of semantic information alone, a strategy useless in classic tasks. Here a medial frontal (400 to 500 ms) episodic memory effect was revealed in both classic and false memory tasks, whereas a parietal (500 to 700 ms) episodic memory effect was found only in the classic task. In the false memory task a large, parietally focused positivity was evident for NEW items, assumed to reflect a targetlike response to new semantic information. The brain activity underlying false memory effects, therefore, cannot be interpreted as a straightforward example of that arising during a standard recognition task. [source]


    Association between respiratory symptom score and 30-year cause-specific mortality and lung cancer incidence

    THE CLINICAL RESPIRATORY JOURNAL, Issue 2008
    A. Frostad
    Abstract Introduction:, Respiratory symptoms are among the main reasons why patients make contact with healthcare professionals and they are associated with several diseases. Objective:, The aim of this study was to investigate the relationship between respiratory symptoms reported at one time and 30 years cause-specific mortality and incidence of lung cancer in an urban Norwegian population. Materials and Methods:, A total of 19 998 men and women, aged 15,70 years, were in 1972 selected from the general population of Oslo. They received a postal respiratory questionnaire (response rate 89%). All were followed for 30 years for end-point mortality and for lung cancer. The association between respiratory symptoms, given as a symptom load, and end point of interest were investigated separately for men and women by multivariable analyses, with adjustment for age, occupational exposure to air pollution and smoking habits. Results:, A total of 6710 individuals died during follow-up. Obstructive lung diseases (OLDs) and pneumonia accounted for 250 and 293 of the total deaths, respectively. Ischaemic heart disease (IHD) accounted for 1572; stroke accounted for 653 of all deaths. Lung cancer developed in 352 persons during follow-up. The adjusted hazard ratio for mortality from OLD and pneumonia, IHD and stroke increased in a dose,response manner with symptom score, more strongly for OLD and IHD than for pneumonia and stroke. Conclusions:, Respiratory symptoms were positively associated with mortality from OLD, pneumonia, IHD and stroke, and incidence of lung cancer. This association was significant for mortality from OLD and IHD. Please cite this paper as: Frostad A. Association between respiratory symptom score and 30-year cause-specific mortality and lung cancer incidence. The Clinical Respiratory Journal 2008; 2: 53,58. [source]


    THE COSTUMES OF OLD AND MIDDLE COMEDY

    BULLETIN OF THE INSTITUTE OF CLASSICAL STUDIES, Issue 1 2006
    ALAN HUGHES
    First page of article [source]


    Ambulatory Phlebectomy Turned 2400 Years Old

    DERMATOLOGIC SURGERY, Issue 5 2004
    Jose Antonio Olivencia MD
    First page of article [source]


    Old enough for a beer?

    ADDICTION, Issue 9 2008
    Compliance with minimum legal age for alcohol purchases in monopoly, Norway, other off-premise outlets in Finland
    ABSTRACT Aim To assess whether government monopoly outlets comply better with minimum legal age for purchase of alcohol compared to other off-premise outlets for alcohol sales. Methods Under-age-appearing 18-year-olds attempted to purchase alcohol in off-premise outlets applying identical procedures in Finland (n = 290) and Norway (n = 170). Outcomes were measured as whether or not the buyers were asked to present an identity (ID) card and whether or not they succeeded in purchasing alcohol. Results The buyers were asked to present an ID card in slightly more than half the attempts, and they succeeded in purchasing alcohol in 48% of the cases. The buyers were more likely to be requested to present an ID card and less likely to succeed in purchasing alcohol in monopoly outlets compared to other types of outlets, and also when other outcome predictors, such as age and gender of salesperson and crowdedness in the outlet, were taken into account. Conclusion Monopoly outlets may facilitate compliance with minimum legal age for purchase of alcohol. [source]


    Meaningful Voices, Old and New

    FAMILY PROCESS, Issue 4 2004
    Evan Imber-Black
    No abstract is available for this article. [source]


    University Strategy in an Age of Uncertainty: The Effect of Higher Education Funding on Old and New Universities

    HIGHER EDUCATION QUARTERLY, Issue 1 2003
    Heather RolfeArticle first published online: 27 OCT 200
    This paper explores the effects of changes in funding arrangements, and particularly in tuition fees, on universities and their strategic responses to these changes. Using data from interviews with senior managers in four universities, it finds the most prestigious, pre-1992, university largely unaffected by tuition fees and the others responding to changes in application patterns and intake. However, the effects of tuition fees on university strategy are not easily separated from other changes in the funding of Higher Education, and universities' strategies were strongly influenced by the need to reduce costs and to generate income. A second major concern of all four universities was quality, both of inputs such as students and staff and of outputs, in degree results and ratings in employability, research, teaching and other activities. Marketing was assuming a position of increasing importance, with universities striving to develop a ,brand' to attract students, staff and funding. [source]


    The Immigrant Threat: The Integration of Old and New Migrants in Western Europe since 1850 By Leo Lucassen

    HISTORY, Issue 305 2007
    BEN BRABER
    No abstract is available for this article. [source]


    Protecting the Old in a Young Economy: Old Age Insurance in the West Bank and Gaza Strip

    INTERNATIONAL SOCIAL SECURITY REVIEW, Issue 3 2000
    Markus Loewe
    Taking the West Bank and Gaza Strip as a reference point, this paper looks at social protection in developing economies, which are beset by economic stagnation, widespread poverty and unemployment. If the main breadwinner dies, is unable to work or is an older person, these factors are prime causes of absolute poverty. This is hardly surprising, since private and public systems of social security are totally inadequate in this area in particular. Current thinking on social security suggests that what is needed is the rapid introduction of a comprehensive system of retirement provision, comprising a mandatory capital-funded insurance component, with defined contributions, administered on a decentralized basis; and a state-administered pay-as-you-go basic insurance component with lump-sum transfers to safeguard the poorest. A system of this kind works to prevent poverty in old age by redistributing funds from some individuals to others and ensuring an income for life, and it represents a compromise between a fair return on what people have contributed and a fair distribution over society as a whole. It is thus a major force for stability in society. [source]


    Regionalism: Old and New

    INTERNATIONAL STUDIES REVIEW, Issue 1 2003
    Raimo Väyrynen
    This review of recent literature on political, economic, and cultural regionalism shows that this area of inquiry has become increasingly fragmented not only as a result of debates between the protagonists of methodological approaches but also because of underlying changes in international relations. Traditional views concerning the state-centric regional system are being challenged by the concentration of political and military power at the top as well as by transnational networks built around economic ties and cultural identities. Early post-Cold War expectations that regions and regional concerts would form the foundation for a new international order have proven untenable. Instead, regions appear to arise either through the dissemination of various transactions and externalities or as protection against the hegemony of capitalist globalization and great-power politics. Older conceptions of regionalism need to be redefined and reintegrated into current international relations theories. [source]


    Shared Memory: John Hampden, New World and Old

    JOURNAL FOR EIGHTEENTH-CENTURY STUDIES, Issue 2 2009
    MAIJA JANSSON
    [source]


    Cardiovascular Disease Is Associated with Greater Incident Dehydroepiandrosterone Sulfate Decline in the Oldest Old: The Cardiovascular Health Study All Stars Study

    JOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 3 2010
    Jason L. Sanders BA
    OBJECTIVES: To describe cross-sectional and longitudinal associations with dehydroepiandrosterone sulfate (DHEAS) and change in DHEAS with age. DESIGN: Longitudinal cohort study. SETTING: Pittsburgh, Pennsylvania. PARTICIPANTS: Cardiovascular Health Study All Stars study participants assessed in 2005/06 (N=989, mean age 85.2, 63.5% women, 16.5% African American). MEASUREMENTS: Health characteristics were assessed in 2005/06 according to DHEAS level, mean DHEAS and DHEAS change across age categories were tested, and linear and logistic regression was used to identify factors present in 1996/97 associated with continuous and categorical DHEAS change. RESULTS: Mean ± standard deviation DHEAS was 0.555 ± 0.414 ,g/mL in 1996/97 and 0.482 ± 0.449 ,g/mL in 2005/06 for women and 0.845 ± 0.520 ,g/mL in 1996/97 and 0.658 ± 0.516 ,g/mL in 2005/06 for men. In 2005/06, DHEAS was lower in women and subjects with cardiovascular disease (CVD) and chronic pulmonary disease and higher for African Americans and subjects with hypertension and high cholesterol. Mean DHEAS change was greater in men (,0.200 ,g/mL) than in women (,0.078 ,g/mL) (P<.001). Each 1-year increase in age attenuated the effect of male sex by 0.01 ,g/mL (P=.009), abolishing the sex difference in DHEAS change by age 79. Presence of CVD before the study period was associated with greater absolute DHEAS change (,=,0.04 ,g/mL, P=.04) and with the fourth quartile of DHEAS change versus the first to third quartiles (odds ratio=1.46, 95% confidence interval=1.03,2.05). CONCLUSION: DHEAS change continues into very old age, is not homogenous, is affected by sex, and is associated with prevalent CVD. Future studies should investigate factors that might accelerate DHEAS decline. [source]


    The Tumor Necrosis Factor Alpha ,308G>A Polymorphism Is Associated with Dementia in the Oldest Old

    JOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 8 2004
    Helle Bruunsgaard MD
    Objectives: To test the hypothesis that the tumor necrosis factor (TNF) ,308 G>A promoter gene polymorphism is a risk factor in age-related dementia and longevity. Design: A cross-sectional and a longitudinal study. Setting: A population-based sample of Danish centenarians. Participants: One hundred-year-old Danes (n=122) from "The Longitudinal Study of Danish Centenarians." Octogenarians (n=174) and healthy volunteers aged 18 to 30 (n=47) served as reference groups. Methods: Whether the distribution of TNF ,308 GG/GA/AA genotypes were different in centenarians than in younger age groups was investigated (Fischer exact test). Furthermore, whether the TNF ,308 G>A polymorphism was associated with the prevalence of dementia (logistic regression analysis), the plasma level of TNF-, (analysis of variance), and mortality in the following 5 years (Cox regression analysis) within the cohort of centenarians was tested. Results: The distribution of TNF ,308 genotypes was not different across the three different age groups, but the GA genotype was associated with decreased prevalence of dementia in centenarians. The few centenarians with AA carrier status had higher mortality risk and tended to show higher plasma levels of TNF-,, but the significance was questionable due to a low number of subjects with this genotype. Conclusion: It is possible that the TNF ,308 A allele is maintained during aging because subjects who are heterozygous for this polymorphism possess the optimal inflammatory response with regard to protection against age-related neurodegeneration. [source]


    Muscle Strength After Resistance Training Is Inversely Correlated with Baseline Levels of Soluble Tumor Necrosis Factor Receptors in the Oldest Old

    JOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 2 2004
    Helle Bruunsgaard MD
    Objectives:, To test the hypothesis that physical exercise induces an antiinflammatory response that is associated with reduced chronic activation of the tumor necrosis factor (TNF)-alpha system in frail elders and that the increase in muscle strength after resistance training is limited by systemic low-grade inflammation. Design:, A 12-week controlled resistance-training study. Setting:, Nursing homes in Copenhagen, Denmark. Participants:, Twenty-one frail nursing home residents aged 86 to 95 completed the study. Intervention:, Ten participants were randomized to a program of resistance training of knee extensors and flexors three times a week for 12 weeks; the remaining 11 participants served as a control group who joined social activities supervised by an occupation therapist. Measurements:, Muscle strength, plasma levels of TNF-,, soluble TNF receptor (sTNFR)-1, and interleukin (IL)-6 were measured before and at the end of the intervention period. Results:, The training program improved muscle strength but did not affect plasma levels of TNF-, and sTNFR-I or IL-6. However, plasma levels of sTNFR-I at baseline were inversely correlated with the increase in muscle strength. Conclusion:, Low-grade activation of the TNF system could limit the increase in muscle strength after resistance training in the oldest old. Furthermore, data suggest that theantiinflammatory response induced by 12 weeks of resistance training is not sufficient to reduce chronic activation of the TNF system, but the small sample size limited this interpretation. [source]


    Exercise in the Oldest Old: Some New Insights and Unanswered Questions

    JOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 12 2002
    FRACP, Maria A. Fiatarone Singh MD
    No abstract is available for this article. [source]


    Struggling To Be Happy , Even When I'm Old

    JOURNAL OF APPLIED PHILOSOPHY, Issue 1 2002
    Margaret Gullan-Whur
    My thesis seeks to reduce what may be a natural human antipathy to ageing and/or the elderly by working with one distinctive and consistently approved feature of some older people. This feature is a bold and cheerful struggle within a self-chosen project. The argument opens by distinguishing short-term gratification from lasting, fulfilling happiness, and showing the link between gratification and dependence. Three kinds of struggle (non-voluntary, part-voluntary and positive) are then outlined and exemplified. Gerontological and anthropological research suggest that attitudes to struggle are fixed early in life, and while in the past they mitigated for or against successful survival, they now influence happiness and coping in later life. I argue that the negative effects of the first two kinds of struggle - which are often misguided, grudging or ,no-win' struggles - are responsible for the rigidity, narcissism and resentment disliked in some older people. Self-respect, contrasted with self-righteousness, is shown to accrue only from the positive (voluntary and congenial) struggle that seems at any age to deflect or compensate for depression, disappointment, loneliness and illness. [source]


    Inter-ocean dispersal is an important mechanism in the zoogeography of hakes (Pisces: Merluccius spp.)

    JOURNAL OF BIOGEOGRAPHY, Issue 6 2001
    W. Stewart Grant
    Aim To present new genetic data and to review available published genetic data that bear on the phylogeny of hakes in the genus Merluccius. To construct a zoogeographical model from a summary phylogenetic tree with dated nodes. To search for an explanation of antitropical distributions in hakes. To assess peripheral isolate, centrifugal and vicariance models of speciation in view of the molecular phylogeny and zoogeography of hakes. Locations Northern and southern Atlantic Ocean, eastern Pacific Ocean, South Pacific Ocean. Methods Electrophoretic analysis of 20 allozyme loci in 10 species of hakes. Phylogenetic tree construction with parsimony and bootstrap methods. Reanalysis of previous genetic data. Analysis of zoogeographical patterns with geographical distributions of molecular genetic markers. Results Phylogenetic analyses of new and previous allozyme data and previous mitochondrial DNA data indicate a deep genetic partition between Old- and New-World hakes with genetic distances corresponding to 10,15 Myr of separation. This time marks a widening rift between Europe and North America and a rapid drop in ocean temperatures that subdivided an ancestral population of North Atlantic hake. Two Old-World clades spanning the equator include pairs of sister taxa separated by tropical waters. Divergence times between these pairs of sister-taxa variously date to the early Pliocene and late Pleistocene. Amongst New-World hakes, pairs of sister taxa are separated by equatorial waters, by the Southern Ocean, and by the Panama Isthmus. These genetic separations reflect isolation by the rise of the Isthmus 3,4 Ma and by Pliocene and Pleistocene dispersals. Pairs of species occurring in sympatry or parapatry in six regions do not reflect sister-species relationships, but appear to reflect allopatric divergence and back dispersals of descendent species. Some geographically isolated regional populations originating within the last few hundreds of thousands of years merit subspecies designations. Conclusions Vicariance from tectonic movement of continental plates or ridge formation cannot account for the disjunct distributions of most hake sister taxa. Molecular genetic divergences place the origin of most hake species diversity in the last 2,3 Myr, a period of negligible tectonic activity. Distributions of many hake species appear to have resulted from dispersals and back dispersals across both warm equatorial waters and cool waters in the Southern Ocean, driven by oscillations in climate and ocean temperatures. Genetic and ecological divergence prevents hybridization and competitive exclusion between sympatric species pairs in six regions. Sister-taxa relationships and estimates of divergence are consistent with the modified peripheral isolate model of speciation in which vicariances, range expansions and contractions, dispersals and founder events lead to isolated populations that subsequently diverge to form new species. [source]


    Old is Gold: Tip Electrograms to Diagnose Pacemaker Lead Perforation

    JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, Issue 10 2002
    KIRAN CHANDAN M.D.
    [source]


    Barley yellow dwarf viruses (BYDVs) preserved in herbarium specimens illuminate historical disease ecology of invasive and native grasses

    JOURNAL OF ECOLOGY, Issue 6 2007
    CAROLYN M. MALMSTROM
    Summary 1In plant invasion ecology, viruses and other pathogens are often considered in terms of the enemy release hypothesis, which predicts that plants become invasive in new ranges if they escape pathogens from their home range. However, pathogens may sometimes facilitate host spread rather than hinder it. 2Previously, we hypothesized that apparent competition mediated by barley and cereal yellow dwarf viruses (Luteoviridae: BYDVs, CYDVs) may have facilitated historical grassland invasion in California, USA, where Eurasian grasses displaced native grasses in the 18th and 19th centuries (the disease facilitation hypotheses). However, this could have happened only if the viruses were present during the invasion, which is unknown. 3To investigate the historical ecology of BYDVs in California grasses, we analysed preserved virus infections in herbarium specimens and used the historical virus sequences to determine rough time estimates of relevant phylogenetic events. 4The historical viral RNA sequences we identified in invasive and native grasses date from 1917 and are among the oldest recovered from plants thus far and the oldest from North America. 5Herbarium evidence and phylogenetic analysis suggest that BYDVs were likely to have been present in wild grasses during the California grassland invasion and to have shared some functional characteristics with present-day isolates, supporting the disease facilitation hypothesis. 6We found evidence of virus spread from California to Australia (or, less likely, from Australia to California) in the late 19th century, when much horticultural exchange occurred, as well as potential correspondence in the timing of virus diversification events and the beginning of extensive human exchange between the Old and New Worlds. 7Synthesis. Increasing evidence indicates that viruses are important in the ecology of grasslands and may, in some cases, mediate apparent competition among species. Historical data provide essential insight into plant virus ecology and suggest the need to examine human influence on plant virus diversification and spread within natural ecosystems. [source]


    Co-evolution of plumage characteristics and winter sociality in New and Old World sparrows

    JOURNAL OF EVOLUTIONARY BIOLOGY, Issue 12 2009
    E. A. TIBBETTS
    Abstract Understanding the evolution of phenotypic diversity, including the stunning array of avian plumage characters, is a central goal of evolutionary biology. Here, we applied a comparative analysis to test factors associated with the origin and maintenance of black chest and throat patches, which in some taxa are referred to as ,badges-of-status'. Specifically, we tested whether the evolution of black colour patches in Old and New World sparrows is consistent with a signalling function during the nonbreeding season or breeding season. We found no positive associations between patch evolution and polygyny or summer sociality. Instead, patch evolution is significantly associated with sociality during the nonbreeding season. Additionally, unlike typical plumage characteristics under sexual selection, these patches are visible throughout the nonbreeding season. Further, the pattern of patch dimorphism uncovered in this study does not match expectations for a trait that evolved in a reproductive context. In particular, patch dimorphism is not associated with polygyny or the presence of extra-pair mating although other types of plumage dimorphism are strongly associated with nonmonogamous mating systems. Overall, patterns of patch evolution suggest that they are more strongly associated with social competition during the nonbreeding season than sexual competition during the breeding season. These results clarify why some previous work has uncovered puzzling relationships between black plumage patches and reproductive behaviour. We discuss these findings in the context of signal theory and previous work on badges-of-status. [source]


    Acute Myocardial Infarction Without Disrupted Yellow Plaque in Young Patients Below 50 Years Old

    JOURNAL OF INTERVENTIONAL CARDIOLOGY, Issue 3 2007
    F.A.C.C., F.E.S.C., F.J.C.C., Ph.D., YASUNORI UEDA M.D.
    Objective: Thrombosis caused by disrupted yellow plaque is regarded as a cause of acute myocardial infarction (MI). However, it has not been clarified if young patients have the same pathophysiology as older ones. Therefore, we elucidated clinical and angioscopic characteristics of young patients. Methods: Among a series of patients (n = 893) who received catheterization for acute MI, clinical characteristics were compared between patients <50 years (n = 66) and the rest of patients. Angioscopic appearance of culprit lesions was evaluated in 20 young patients in whom angioscopic examination was successfully performed. It was determined if culprit lesions had disrupted yellow plaque with thrombus (DYP&T). Results: Patients <50 years had higher prevalence of smoking (68% vs. 48%, P = 0.001), obesity (42% vs. 15%, P < 0.0001), and hypercholesterolemia (56% vs. 35%, P = 0.0005) than those ,50 years. DYP&T was detected at culprit lesions in 14 (70%) patients. Prevalence of DYP&T was lower in patients <40 years (44% vs. 91%, P = 0.02) than those between 40 and 50 years. Patients <40 years had a trend for higher prevalence of smoking (88% vs. 62%, P = 0.05) than those between 40 and 50 years. Conclusions: Patients with acute MI < 50 years, especially <40 years, had lower prevalence of DYP&T but higher prevalence of smoking, obesity, and hypercholesterolemia. Smoking may play an important role for thrombotic occlusion at lesions with relatively low thrombogenic potential. [source]


    A Door of Hope Re-opened: The Fifth Monarchy, King Charles and King Jesus

    JOURNAL OF RELIGIOUS HISTORY, Issue 1 2008
    BERNARD CAPP
    A Door of Hope was the manifesto of the Fifth Monarchists' desperate uprising in London in January 1661, a few months after the Restoration of Charles II. While the rising itself is well known, its manifesto has never been examined in detail. Probably based on a sermon to Venner's congregation, it displays a defiant conviction that the Restoration could be understood as part of God's providential plan, the next step towards the imminent kingdom of Christ on earth. But it also reaches out to a much wider constituency, all the supporters of the "Good Old Cause," offering a programme that might appeal to many radicals. And the author draws on secular, republican discourse to buttress his apocalyptic claims, revealing close links between even the most extreme Fifth Monarchists and wider currents of interregnum radicalism. [source]