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Obtained Compounds (obtained + compound)
Selected AbstractsSynthesis, NMR, and Conformational Studies of Cyclic Oligo-(1,6)-,- D -Glucosamines,EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 13 2010Marina L. Gening Abstract The first synthesis of a series of homologous cyclic oligo-(1,6)-,- D -glucosamines consisting of two to seven residues and representing a new type of functionalized cyclic oligosaccharides is reported. Remarkably high yields of the studied macrocyclization reaction irrespective of the length of the acyclic precursors were observed. In the case of compounds constituted of four to seven glucosamine units ,-stereoisomers formed as side products despite the presence of a strongly participating 2- N -phthaloyl group to control ,-glycosylation. Both phenomena may be accounted for by conformational features of the linear bifunctional precursors. According to computer modeling and NMR conformational studies, the described linear (1,6)-,-linked oligoglucosamines exist in a right-handed helix-like conformation, in which the glycosyl donor and acceptor moieties are prearranged in a way that facilitates intramolecular glycosylation from the ,-side. Prepared cyclo-oligoglucosamines differ in their conformational flexibilities, as illustrated by their spectral characteristics and calculated asphericity distributions. Moreover, the obtained compounds do not possess a distinct hydrophobic cavity, which is in contrast to the well-known cyclodextrins. All these characteristics provide an excellent basis for the use of these novel cyclic oligosaccharides as scaffolds for the construction of biomolecular conjugates. [source] Classical Benzotriazole-Mediated , -Aminoalkylations of Alkynes: Synthesis and Characterization of Alk-2-yn-1-amines as Amphiphilic MaterialsHELVETICA CHIMICA ACTA, Issue 9 2007Krzysztof Abstract Reactions of readily available and stable benzotriazolemethanamines 1a,l, obtained from aldehydes and secondary amines (Scheme,2), gave the expected alk-2-yn-1-amines 3a,t (Scheme,3). The amphiphilic character of the synthesized products was responsible for physicochemical measurements. Specific aggregation properties of the obtained compounds make them useful as electroactive materials in the Langmuir,Blodgett technique. [source] Synthesis of the new adducts of imines and enamines with PH acids and their derivatives,HETEROATOM CHEMISTRY, Issue 2 2009Andrey A. Prishchenko Nucleophilic or radical addition of esters of trivalent organophosphorus acids with PH fragments to various imines and enamines is proposed as convenient methods for the synthesis of new substituted aminomethyl organophosphorus compounds with three-, four-, and five-coordinated phosphorus. Also the new functionalized derivatives of these compounds with acyl and methanesulfonyl moieties are synthesized, and some properties of the obtained compounds are presented. © 2009 Wiley Periodicals, Inc. Heteroatom Chem 20:70,80, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20513 [source] Reaction of ,-carbonyl substituted 1,3,3-trimethyl-2-methyleneindolines with phosphorus(III) halidesHETEROATOM CHEMISTRY, Issue 1 2003Alexej A. Chekotylo The phosphorylation of N -benzoyl-2-(1,3,3-trimethyl-2-methyleneindoline)acetamide (2) and ,-(3-dimethylamino)benzoyl-1,3,3-trimethyl-2-methyleneindoline (6) with phosphorus(III) halides resulted in the formation of 2,3-dihydro-4H -1,5,2-oxazaphosphinin-4-one and 1,2-dihydro-3H -phosphindol-3-one systems, respectively. The properties of the obtained compounds were studied. Further cyclization of 1,2-dihydro-3H -phosphindol-3-one into dihydrophosphindolo[3,2- c]pyrazole was carried out. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:23,28, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10060 [source] | ||||||||||