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Aryl Radical Cyclization (aryl + radical_cyclization)

Distribution by Scientific Domains
Chemistry100%

Selected Abstracts

The First Samarium(II)-Mediated Aryl Radical Cyclization onto an Aromatic Ring.

CHEMINFORM, Issue 10 2005
Hiroaki Ohno
Abstract For Abstract see ChemInform Abstract in Full Text. [source]

Regioselective Aryl Radical Cyclization: Access to Pyrimidine-Anellated Spiro Heterocycles Through 5-exo Ring Closure.

CHEMINFORM, Issue 1 2005
K. C. Majumdar
Abstract For Abstract see ChemInform Abstract in Full Text. [source]

Synthesis of Benzomacrolactam by 12-endo Selective Aryl Radical Cyclization of N-(4-Allyloxybutyl)-2-iodobenzamide.

CHEMINFORM, Issue 27 2003
Andre Augusto Gomes Faraco
Abstract For Abstract see ChemInform Abstract in Full Text. [source]

ChemInform Abstract: Aryl Radical Cyclization onto Pyrroles.

CHEMINFORM, Issue 29 2002
Carmen Escolano
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

Controlling the regiochemistry of radical cyclizations

THE CHEMICAL RECORD, Issue 1 2006
Hiroyuki Ishibashi
Abstract This review describes the results of our recent studies on the control of the regiochemistry of radical cyclizations. N-vinylic ,-chloroacetamides generally cyclized in a 5- endo-trig manner to give five-membered lactams, whereas 4- exo-trig cyclization occurred when the cyclized radical intermediates were highly stabilized by an adjacent phenyl or phenylthio group to afford ,-lactams. The 5- exo or 6- exo cyclization of aryl radicals onto the alkenic bond of enamides could be shifted to the corresponding 6- endo or 7- endo mode of cyclization by a positional change of the carbonyl group of enamides. The 6- endo - and 7- endo -selective aryl radical cyclizations were applied to radical cascades for the synthesis of alkaloids such as phenanthroindolizidine, cephalotaxine skeleton, and lennoxamine. The 5- exo-trig cyclization of an alkyl radical onto the alkenyl bond of enamides could also be shifted to the 6- endo mode by a positional change of the carbonyl group of enamides. The 6- endo - selective cyclization was applied to the radical cascade to afford a cylindricine skeleton. Other examples of controlling the regiochemistry of radical cyclizations and their applications to the synthesis of natural products are also discussed. © 2006 The Japan Chemical Journal Forum and Wiley Periodicals, Inc. Chem Rec 6: 23,31; 2006: Published online in Wiley InterScience (www.interscience.wiley.com) DOI 10.1002/tcr.20069 [source]