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Aryl Ketones (aryl + ketone)
Selected AbstractsA Ruthenium Catalyst that Does not Require an N,H Ligand to Achieve High Enantioselectivity for Hydrogenation of an Alkyl Aryl Ketone.CHEMINFORM, Issue 27 2003Carolyn G. Leong Abstract For Abstract see ChemInform Abstract in Full Text. [source] ChemInform Abstract: Asymmetric Synthesis of 2-Azido-1-arylethanols from Azido Aryl Ketone-,-cyclodextrin Complexes and Sodium Borohydride in Water.CHEMINFORM, Issue 6 2002M. Arjun Reddy Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Synthesis of Biaryls and Aryl Ketones via Microwave-Assisted Decarboxylative Cross-CouplingsADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 16 2009Lukas Abstract A protocol for the microwave-assisted decarboxylative cross-couplings of carboxylic acid salts with aryl halides has been developed that allows the synthesis of various biaryls and aryl ketones in high yields. After careful adaptation of the bimetallic catalyst system and reaction conditions, these mechanistically complex transformations can now be performed within only five minutes in concentrated solution in a sealed vessel. This greatly simplified reaction protocol is ideally suited for applications in parallel synthesis and drug discovery. [source] ChemInform Abstract: Copper Catalyzed Arylation/C,C Bond Activation: An Approach Toward ,-Aryl Ketones.CHEMINFORM, Issue 41 2010Chuan He Abstract A wide range of ,-aryl ketones is prepared from the aryl iodides or bromides with ,-diketones. [source] ChemInform Abstract: Efficient Synthesis of Alkyl Aryl Ketones and Ketals via Palladium-Catalyzed Regioselective Arylation of Vinyl Ethers.CHEMINFORM, Issue 38 2010Mingcui Liu Abstract Excellent regioselectivity is achieved in the Pd,dppp-catalyzed arylation of vinyl ethers with various aryl bromides in ethylene glycol. [source] ChemInform Abstract: ,-Arylation of Aryl Ketones: Expanding the Scope of the Truce,Smiles Rearrangement.CHEMINFORM, Issue 9 2009Timothy J. Snape Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Zinc-Mediated Reductive Cyclodimerization of ,,,-Unsaturated Aryl Ketones under Aqueous Conditions.CHEMINFORM, Issue 1 2008Anil Kumar Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Cationic Rh(I)/Modified-BINAP-Catalyzed Reactions of Carbonyl Compounds with 1,6-Diynes Leading to Dienones and ortho-Functionalized Aryl Ketones.CHEMINFORM, Issue 39 2007Ken Tanaka Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] A Convenient and Environmentally Benign Method of Reducing Aryl Ketones or Aldehydes by Zinc Powder in an Aqueous Alkaline Solution.CHEMINFORM, Issue 37 2007Chao-Zhi Zhang Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Efficient ,-Chlorination of Aryl Ketones Using Aluminum Chloride/Urea,Hydrogen Peroxide in Ionic Liquid.CHEMINFORM, Issue 35 2006Jong Chan Lee Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Synthesis of ,-Aryl Ketones by Tetraphosphine/Palladium Catalyzed Heck Reactions of 2- or 3-Substituted Allylic Alcohols with Aryl Bromides.CHEMINFORM, Issue 34 2006Florian Berthiol Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Selective Oxidation of Aryl Ketones to ,-Diketones with 4-Aminoperoxybenzoic Acid Supported on Silica Gel in the Presence of Air.CHEMINFORM, Issue 11 2005Dadkhoda Ghazanfari Abstract For Abstract see ChemInform Abstract in Full Text. [source] A Convenient and Environmentally Benign Method of Reducing Aryl Ketones or Aldehydes by Zinc Powder in an Aqueous Alkaline SolutionCHINESE JOURNAL OF CHEMISTRY, Issue 5 2007Chao-Zhi Zhang Abstract A convenient and environmentally benign method for reducing the carbonyl group in hydroxy- and amino- 9,10-anthracenediones, ortho (or para) acyl phenols and acyl anilines to a methylene group by zinc powder in an aqueous sodium hydroxide solution was reported. Based on theoretical calculations using the density functional theory (DFT), the mechanism of these reduction reactions was postulated. This mechanism can be applied to help predicting the reduced products of aryl ketones (or aldehydes) in an alkaline solution. [source] Achiral and chiral separations using MEKC, polyelectrolyte multilayer coatings, and mixed mode separation techniques with molecular micellesELECTROPHORESIS, Issue 6 2010Candace A. Luces Abstract Mixed mode (MM) separation using a combination of MEKC and polyelectrolyte multilayer (PEM) coatings is herein reported for the separation of achiral and chiral analytes. Many analytes are difficult to separate by MEKC and PEM coatings alone. Therefore, the implementation of a MM separation provides several advantages for overcoming the limitations of these well-established methods. In this study, it was observed that achiral separations using MEKC and PEM coatings individually resulted in partial resolution of eight very similar aryl ketones when the molecular micelle (sodium poly(N -undecanoyl- L -glycinate)) concentration was varied from 0.25 to 1.00%,w/v and the bilayer number varied from 2 to 4. However, when MM separation was introduced, baseline resolution was achieved for all eight analytes. In the case of chiral separations, temazepam, aminoglutethimide, benzoin, benzoin methyl ether, and coumachlor were separated using the three separation techniques. For chiral separations, the chiral molecular micelle, sodium poly(N -undecanoyl- L -leucylvalinate), was employed at concentrations of 0.25,1.50%,w/v for both MEKC and PEM coatings. Overall, the results revealed partial separation with MEKC and PEM coatings individually. However, MM separation enabled baseline separation of each chiral mixture. The separation of achiral and chiral compounds from different compound classes demonstrates the versatility of this MM approach. [source] Complete Chiral Induction from Enantiopure 1,2-Diamines to Benzophenone-Based Achiral Bisphosphane Ligands in Noyori-Type RuII CatalystsEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 16 2006Qing Jing Abstract We report the design and synthesis of a novel class of RuII catalysts (3) composed of achiral benzophenone-based bisphosphane ligands and enantiopure 1,2-diamines for the asymmetric hydrogenation of aryl ketones. The developed catalysts show excellent enantioselectivities (up to 97,% ee) and activities (up to S/C = 10,000) in the hydrogenation of a variety of aromatic ketones.Complete chiral induction from the enantiopure 1,2-diamine to the achiral bisphosphane ligand was observed. The coordination of the C=O moiety in 3 to the cationic RuII center is considered to be of key importance in providing a higher thermodynamic and kinetic rotation barrier for the flexible bisphosphane ligand, resulting in the preferential formation of only one diastereomer, and thus explaining the high enantioselectivity of the catalyst. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006) [source] A Novel D2 -Symmetrical Chiral Tetraoxazoline Ligand for Highly Enantioselective Hydrosilylation of Aromatic KetonesADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 7 2010Wei Jie Li Abstract A novel D2 -symmetrical chiral tetraoxazoline ligand was synthesized from 1,2,4,5-benzenetetracarboxylic acid and L -valinol via a one-pot reaction, and the asymmetric hydrosilylation of aromatic ketones was carried out in dichloromethane in the presence of 1.0,mol% of a bivalent copper ion catalyst with the tetraoxazoline to give optically active secondary alcohols. The chiral catalyst showed excellent activities and enantioselectivities in the hydrosilylation of aryl ketones with up to 99% ee. [source] A Spirocyclic Chiral Borate for Catalytic Enantioselective Nozaki-Hiyama Allylation of KetonesADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 18 2009Xin-Ren Huang Abstract A new class of chiral spirocyclic borate ligands 5a,d with a rigid borocycle has been developed. The catalyst formed from chromium(II)- 5a promotes the highly efficient enantioselective Nozaki,Hiyama allylation of alkyl and aryl ketones using allyl bromide. The scope of the present method is shown to be wide, and it affords an efficient access to chiral tertiary homoallylic alcohols. [source] Synthesis of Biaryls and Aryl Ketones via Microwave-Assisted Decarboxylative Cross-CouplingsADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 16 2009Lukas Abstract A protocol for the microwave-assisted decarboxylative cross-couplings of carboxylic acid salts with aryl halides has been developed that allows the synthesis of various biaryls and aryl ketones in high yields. After careful adaptation of the bimetallic catalyst system and reaction conditions, these mechanistically complex transformations can now be performed within only five minutes in concentrated solution in a sealed vessel. This greatly simplified reaction protocol is ideally suited for applications in parallel synthesis and drug discovery. [source] Microwave-Assisted Oxidation of Side Chain Arenes by MagtrieveTMADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 12 2003Marcin Lukasiewicz Abstract A commercial tetravalent chromium dioxide (MagtrieveTM) as a magnetically retrievable oxidant is shown to be a very useful compound for microwave-assisted and conventional transformation of aromatic and alkyl aromatic molecules into the corresponding aryl ketones, quinones or lactones. [source] ChemInform Abstract: Copper Catalyzed Arylation/C,C Bond Activation: An Approach Toward ,-Aryl Ketones.CHEMINFORM, Issue 41 2010Chuan He Abstract A wide range of ,-aryl ketones is prepared from the aryl iodides or bromides with ,-diketones. [source] RhIII - and IrIII -Catalyzed Asymmetric Transfer Hydrogenation of Ketones in WaterCHEMISTRY - A EUROPEAN JOURNAL, Issue 7 2008Xiaofeng Wu Dr. Abstract Asymmetric transfer hydrogenation (ATH) of ketones by formate in neat water is shown to be viable with Rh-TsDPEN and Ir-TsDPEN catalysts, derived in situ from [Cp*MCl2]2 (M=Rh, Ir) and TsDPEN. A variety of ketones were reduced, including nonfunctionalized aryl ketones, heteroaryl ketones, ketoesters, and unsaturated ketones. In comparison with Ir-TsDPEN and the related RuII catalyst, the RhIII catalyst is most efficient in water, affording enantioselectivities of up to 99,% ee at substrate/catalyst (S/C) ratios of 100,1000 even without working under an inert atmosphere. The aqueous phase reduction is shown to be highly pH-dependent; the optimum pH windows for TOF greater than 50,mol,mol,1,h,1 for Rh- and Ir-TsDPEN are 5.5,10.0 and 6.5,8.5, respectively. Outside the pH window, the reduction becomes slow or stagnant depending on the pH. However, the enantioselectivities erode only under acidic conditions. At a higher S/C ratio, the aqueous ATH by Rh-TsDPEN is shown to be product- as well as byproduct-inhibited; the product inhibition appears to stem at least partly from the reaction being reversible. The aqueous phase reduction is simple, efficient and environmentally benign, thus presenting a viable alternative for asymmetric reduction. [source] A Convenient and Environmentally Benign Method of Reducing Aryl Ketones or Aldehydes by Zinc Powder in an Aqueous Alkaline SolutionCHINESE JOURNAL OF CHEMISTRY, Issue 5 2007Chao-Zhi Zhang Abstract A convenient and environmentally benign method for reducing the carbonyl group in hydroxy- and amino- 9,10-anthracenediones, ortho (or para) acyl phenols and acyl anilines to a methylene group by zinc powder in an aqueous sodium hydroxide solution was reported. Based on theoretical calculations using the density functional theory (DFT), the mechanism of these reduction reactions was postulated. This mechanism can be applied to help predicting the reduced products of aryl ketones (or aldehydes) in an alkaline solution. [source] | ||||||||||||||||||||||