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Aryl Bromides (aryl + bromide)
Selected AbstractsEfficient Microwave-Assisted Cyanation of Aryl Bromide.CHEMINFORM, Issue 32 2004Liangzhen Cai Abstract For Abstract see ChemInform Abstract in Full Text. [source] Palladium-Catalyzed C2 or C5 Direct Arylation of 3-Formylthiophene Derivatives with Aryl BromidesEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 4 2010Jia Jia Dong Abstract The system Pd(OAc)2/dppb was found to be an efficient catalyst precursor for the direct arylation of 3-formylthiophene derivatives. When using 3-formylthiophene, the 2-arylated thiophenes were obtained with regioselectivities of 76,86,%, whereas the arylation of 3-formylthiophene diethyl acetal gave the 5-arylated thiophenes with regioselectivities of 64,88,%. These reactions were performed by using only 0.1 mol-% of the catalyst. Moreover, this procedure has been found to be tolerant to a variety of functional groups on the aryl bromide such as formyl, propionyl, benzoyl, nitrile, or nitro. [source] Selective Palladium-Catalysed ipso Arylation of ,,,-Disubstituted Benzo[b]thien-2-ylmethanols with Aryl Bromides using PCy3 as LigandEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 8 2007A. Beatrix Bíró Abstract ,,,-Diphenylbenzo[b]thien-2-ylmethanol was treated with a series of aryl bromides in the presence of palladium(II) acetate and tricyclohexylphosphane to give the appropriate 2-aryl-benzo[b]thiophenes in good to excellent yield with concomitant formation of benzophenone. The reaction wassuccessfully extended to ,,,-diphenylbenzo[b]thien-3-ylmethanol, although in certain cases the transformation was biased by concurrent ortho arylation. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007) [source] One-Pot Synthesis of 5-Substituted 1H -Tetrazoles from Aryl Bromides with Potassium Hexakis(cyano- ,C)ferrate(4,) (K4[Fe(CN)6]) as Cyanide SourceHELVETICA CHIMICA ACTA, Issue 1 2009Yizhong Zhu Abstract A one-pot procedure for the synthesis of 5-substituted 1H -tetrazoles through the three-component reaction between an aryl bromide, potassium hexakis(cyano- ,C)ferrate(4,) (K4[Fe(CN)6]) and NaN3 catalyzed by [Pd(OAc)2] and ZnBr2 in the presence of 1,4-diazabicyclo[2.2.2]octane (dabco) was developed. Furthermore, the reaction occurred under nonacidic conditions and involved a nontoxic cyanide source, making this method a quite attractive one. [source] Palladium-Catalysed Direct Arylation of Heteroaromatics Bearing Unprotected Hydroxyalkyl Functions using Aryl BromidesADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 4 2010Julien Roger Abstract Heteroaromatics bearing unprotected hydroxyalkyl functions can be arylated using aryl or heteroaryl bromides, via palladium-catalysed carbon-hydrogen bond activation/arylation. Good yields were generally obtained using 0.01,0.5,mol% of the air-stable palladium acetate complex as the catalyst. The nature of the base was found to be crucial for the selectivity of this reaction. Potassium acetate led to the direct arylation products whereas caesium carbonate led to the formation of the ether. This procedure is certainly more atom-economic than other methods for the preparation of such compounds, as no protection/deprotection sequence of the hydroxyalkyl function and no preparation of an organometallic derivative is required. [source] Aminations of Aryl Bromides in Water at Room TemperatureADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 11-12 2009Bruce Abstract Unsymmetrical di- and triarylamines can be formed under green chemistry conditions, taking advantage of micellar catalysis leading to palladium-catalyzed aminations at ambient temperatures in water as the only medium. [source] Regioselective C-2 or C-5 Direct Arylation of Pyrroles with Aryl Bromides using a Ligand-Free Palladium CatalystADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 11-12 2009Julien Roger Abstract A simple and atom-economical procedure for the regioselective C-2 or C-5 arylation of pyrroles via a CH bond activation is reported. Only 0.5,0.01 mol% of commercially available and air-stable ligand-free palladium(II) acetate [Pd(OAc)2] was employed as the catalyst. The presence of electron-withdrawing substituents such as formyl, acetyl or ester at the C-2 position of the pyrrole is tolerated. This environmentally attractive procedure has also been found to be tolerant to a very wide variety of functional groups on the aryl bromides such as formyl, acetyl, propionyl, ester, nitrile, nitro, fluoro, methoxy, amino or trifluoromethyl. [source] Atom-Efficient, Palladium-Catalyzed Stille Coupling Reactions of Tetraphenylstannane with Aryl Iodides or Aryl Bromides in Polyethylene Glycol 400 (PEG-400)ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 9 2009Wen-Jun Zhou Abstract The Stille coupling of tetraphenylstannane with aryl iodides or aryl bromides using the bis(triphenylphosphine)palladium dichloride/sodium acetate/polyethylene glycol 400 [PdCl2(PPh3)2/NaOAc/PEG-400] catalytic system at 100,°C has been developed. The reactions were carried out in an atom-efficient way, as 4 equivalents of aryl iodides or aryl bromides coupled effectively with 1 equivalent of tetraphenylstannane to furnish 4 equivalents of the corresponding functionalized biaryls in high yields. [source] Direct B -Alkyl Suzuki,Miyaura Cross-Coupling of Trialkyl- boranes with Aryl Bromides in the Presence of Unmasked Acidic or Basic Functions and Base-Labile Protections under Mild Non-Aqueous ConditionsADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 3 2009Bing Wang Abstract An efficient and chemoselective palladium-catalyzed direct B -alkyl Suzuki,Miyaura cross-coupling of trialkylboranes with diversely functionalized aryl bromides is described. A wide variety of unmasked acidic or basic functions are tolerated. The mild non-aqueous conditions are compatible with aldehydes, ketones, nitriles, chloro substitution as well as base-labile phenolic Piv and TBS protecting groups. The anhydrous conditions were found to be advantageous for aryl bromide substrates. A potent CEPT inhibitor was efficiently synthesised using this protocol. [source] Palladium-Catalyzed Direct C-4 Arylation of 2,5-Disubstituted Furans with Aryl BromidesADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 14-15 2008Aditya Abstract A simple and atom-economic procedure for the selective C-4 arylation of 2,5-disubstituted furans via CH bond activation using electron-deficient aryl bromides is reported. Only 0.5 mol% of the commercially available dimeric (allene)palladium chloride, [Pd(C3H5)Cl]2, was employed as catalyst. This environmentally attractive procedure has been found to be tolerant to a variety of functional groups on the aryl bromide such as carbonyl, nitrile, nitro, fluoro, ester or trifluoromethyl. [source] Nickel(0)/Imidazolium Carbene Catalyst System for Efficient Cross-Coupling of Aryl Bromides and Chlorides with Organomanganese ReagentsADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 9 2006Anne Leleu Abstract N,N, -Bis(2,6-diisopropylphenyl)imidazolium chloride associated with nickel(II) acetylacetonate (3,5 mol,%) was used as catalyst to efficiently cross-couple functionalized aryl bromides with organomanganese reagents. The reactions were performed between 0,°C and room temperature, giving unsymmetrical biaryls in 0.25 to 24,h with 52 to 100,% yields for isolated materials. Aryl chlorides showed slightly diminished reactivity in Ni/2 IPr-catalyzed cross-couplings and good yields could only be attained with activated or neutral substrates. [source] A Convenient High Activity Catalyst for the Sonogashira Coupling of Aryl BromidesADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 9 2005Axel Köllhofer Abstract A mixture of Na2PdCl4, CuI and (t -Bu)3PH+BF4, (molar ratio 4,:,3,:,8) dispersed in H2N(i -Pr)2+Br, can be used as a "single source" precatalyst for the Sonogashira coupling of aryl bromides with various aryl- and alkylacetylenes in HN(i -Pr)2 solvent. Arylacetylenes require just 0.005,mol,% of Pd catalyst at 80,°C, with TOFs ranging between 3,200 and 10,000,h,1. [source] ChemInform Abstract: An Inexpensive Cyclodiphosphazane as an Efficient Ligand for the Palladium-Catalyzed Amination of Aryl Bromides and Chlorides.CHEMINFORM, Issue 7 2010R. Rama Suresh Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Direct Palladium-Catalyzed Arylations of Aryl Bromides with 2/9-Substituted Pyrimido[5,4-b]indolizines.CHEMINFORM, Issue 5 2010Min Jiang Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Ligand-Free-Palladium-Catalyzed Direct 4-Arylation of Isoxazoles Using Aryl Bromides.CHEMINFORM, Issue 2 2010Yacoub Fall Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Sol,Gel Immobilized and Reusable Copper-Catalyst for Arylation of Phenols from Aryl Bromides.CHEMINFORM, Issue 52 2009Sofia Benyahya Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Efficient, Regioselective Palladium-Catalyzed Tandem Heck-Isomerization Reaction of Aryl Bromides and Non-Allylic Benzyl Alcohols.CHEMINFORM, Issue 30 2009Matthew L. Crawley Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Direct Synthesis of Primary Arylamines via C,N Cross-Coupling of Aryl Bromides and Triflates with Amides.CHEMINFORM, Issue 27 2009M. Romero Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Selective Heck Reaction of Aryl Bromides with Cyclopent-2-en-1-one or Cyclohex-2-en-1-one.CHEMINFORM, Issue 21 2009Yacoub Fall Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Per-6-amino-,-cyclodextrin as an Efficient Supramolecular Ligand and Host for Cu(I)-Catalyzed N-Arylation of Imidazole with Aryl Bromides.CHEMINFORM, Issue 15 2009Palaniswamy Suresh Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Regioselective Synthesis of 4,5-Diaryl-1-methyl-1H-imidazoles Including Highly Cytotoxic Derivatives by Pd-Catalyzed Direct C-5 Arylation of 1-Methyl-1H-imidazole with Aryl Bromides.CHEMINFORM, Issue 11 2009Fabio Bellina Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Direct Palladium-Catalyzed C-3 Arylation of Free (NH)-Indoles with Aryl Bromides under Ligandless Conditions.CHEMINFORM, Issue 49 2008Fabio Bellina Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Sterically Demanding, Zwitterionic Trialkylphosphonium Sulfonates as Air-Stable Ligand Precursors for Efficient Palladium-Catalyzed Cross-Couplings of Aryl Bromides and Chlorides.CHEMINFORM, Issue 43 2008William S. Brown Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Synthesis of N-Substituted Indole-3-carboxylic Acid Derivatives via Cu(I)-Catalyzed Intramolecular Amination of Aryl Bromides.CHEMINFORM, Issue 42 2008Ferdinand S. Melkonyan Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Design and Synthesis of Thioether-Imidazolium Chlorides as Efficient Ligands for Palladium-Catalyzed Suzuki,Miyaura Coupling of Aryl Bromides with Arylboronic Acids.CHEMINFORM, Issue 51 2007Masami Kuriyama Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Palladium-Catalyzed Atom-Efficient Cross-Coupling Reactions of Triarylbismuths with Aryl Bromides.CHEMINFORM, Issue 30 2007Maddali L. N. Rao Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Cobalt-Catalyzed Cross-Coupling Reactions of Heterocyclic Chlorides with Arylmagnesium Halides and of Polyfunctionalized Arylcopper Reagents with Aryl Bromides, Chlorides, Fluorides and Tosylates.CHEMINFORM, Issue 12 2007Tobias J. Korn Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Cu(OAc)2/Pyrimidines-Catalyzed Cross-Coupling Reactions of Aryl Iodides and Activated Aryl Bromides with Alkynes under Aerobic, Solvent-Free and Palladium-Free Conditions.CHEMINFORM, Issue 5 2007Ye-Xiang Xie Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Synthesis of ,-Aryl Ketones by Tetraphosphine/Palladium Catalyzed Heck Reactions of 2- or 3-Substituted Allylic Alcohols with Aryl Bromides.CHEMINFORM, Issue 34 2006Florian Berthiol Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Heck Reaction of Aryl Bromides with Pent-4-en-2-ol, 2-Phenylpent-4-en-2-ol, or Hept-6-en-3-ol Catalyzed by a Palladium,Tetraphosphine Complex.CHEMINFORM, Issue 20 2006Florian Berthiol Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] | ||||||||||||||||||||||