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Multidimensional Assessment (multidimensional + assessment)

Distribution by Scientific Domains

Medical Sciences	80%

Selected Abstracts

Multidimensional assessment of female tracheoesophageal prosthetic speech

CLINICAL OTOLARYNGOLOGY, Issue 6 2006
R. Kazi
Objective:, The objective of this study was to undertake a multidimensional assessment of female tracheoesophageal prosthetic speech. Study Design:, A cross-sectional cohort study. Setting:, Head and Neck Unit in a tertiary oncology referral centre. Patients:, Ten female and 10 male total laryngectomy patients with no signs of recurrence and using voice prosthesis were compared to 10 normal female speakers. Intervention(s):, Electroglottographic and acoustic analysis of voice parameters for both sustained vowel /i/ and connected speech, perceptual evaluation using GRBAS (with 2 experienced raters) and questionnaire assessment using the University of Washington Quality of Life and the Voice Handicap Index. Statistical analysis was done using the Statistical Package for Social Sciences, (v. 14, SPSS Inc., Chicago III). Results:, Median age of the female larygectomy patiemts was 65 years (range: 41-81), that of male laryngectomees was 66.5 years (range: 40-79) and that of the normal female subjects was 47.5 years (range: 35-72). All electroglottographic, acoustic parameters and GRBAS ratings of the female laryngectomy patients were significantly worse as compared with the normal female subjects. The median fundamental frequency (111.8 Hz) was comparable to male tracheoesophageal speakers (115.8 Hz). Mean composite University of Washington Quality of Life score and overall Voice Handicap Index score was 79.3(12.5) and 47.5(27.6) for the female laryngectomy patients and for the males was 81.2 (9.6) and 39.4(18.7). Conclusions:, Gender frequency differences as seen in normal subjects are lost following a laryngectomy operation as evidenced by electroglottographic and perceptual data. Although the quality of life scores are comparable to the male tracheoesophageal speakers, they exhibit a greater voice handicap as compared to their male counterparts. [source]

Behavioral economic analysis of cue-elicited craving for alcohol

ADDICTION, Issue 9 2010
James MacKillop
ABSTRACT Aims Craving as a motivational determinant of drug use remains controversial because of ambiguous empirical findings. A behavioral economic approach may clarify the nature of craving, theorizing that subjective craving functionally reflects an acute increase in a drug's value. The current study tested this hypothesis via a multidimensional assessment of alcohol demand over the course of an alcohol cue reactivity procedure. Design One-way within-subjects design. Setting Human laboratory environment. Participants Heavy drinkers (n = 92) underwent exposures to neutral (water) cues followed by personalized alcohol cues. Assessments Participants were assessed for craving, alcohol demand, affect, and salivation following each exposure. Findings Alcohol versus neutral cues significantly increased craving and multiple behavioral economic measures of the relative value of alcohol, including alcohol consumption under conditions of zero cost (intensity), maximum expenditure on alcohol (Omax), persistence in drinking to higher prices (breakpoint) and proportionate price insensitivity (normalized Pmax). Craving was significantly correlated with demand measures at levels ranging from 0.21,0.43. Conclusions These findings support the potential utility of a behavioral economic approach to understanding the role of environmental stimuli in alcohol-related decision making. Specifically, they suggest that the behavioral economic indices of demand may provide complementary motivational information that is related to though not entirely redundant with measures of subjective craving. [source]

Efficacy of Eletriptan in Migraine-Related Functional Impairment: Functional and Work Productivity Outcomes

HEADACHE, Issue 5 2007
Stephen D. Silberstein MD
Objective.,To provide a multidimensional assessment of the extent of functional impairment during an acute migraine attack, and of the improvement in functioning in response to treatment, using 4 concurrently administered scales: the 7-item work productivity questionnaire (PQ-7), the functional assessment in migraine (FAIM) activities and participation (FAIM-A&P) subscale, the FAIM-impact of migraine on mental functioning (FAIM-IMMF) subscale, and the traditional 4-point global functional impairment scale (FIS). Methods.,Outpatients with an International Classification of Headache Disorders diagnosis of migraine were randomized to double-blind treatment of a single attack with either oral eletriptan 20 mg (n = 192) once-daily, eletriptan 40 mg (N = 213) once-daily, or placebo (n = 208). Patients were encouraged to take study medication as soon as they were sure they were experiencing a typical migraine headache, after the aura phase (if present) had ended. Patients with moderate-to-severe functional impairment were identified on each of the 4 disability scales, and 2-hour functional response was compared between treatments. Results.,At baseline, the PQ-7 and FAIM-IMMF items that assessed ability to perform tasks requiring concentration, sustained work or attention, and ability to think quickly or spontaneously, were especially sensitive to the effects of mild headache pain, with 27% to 48% of patients (n = 92-112) reporting moderate-to-severe impairment. Only 11.3% of patients (n = 112) reported this level of impairment due to mild pain on the FIS. Functional response at 2 hours was significantly higher on eletriptan 40 mg versus placebo on the FAIM-A&P (63% vs 36%; n = 218; P < .0001); on the PQ-7 (56% vs 34%; n = 116; P= .0052); and on the FAIM-IMMF (50% vs 34%; n = 215; P= .017). These rates were all lower than the functional response rates on the FIS for eletriptan 40 mg (75%) and eletriptan 20 mg (70%) versus placebo (45%; P < .001). Conclusions.,In this exploratory analysis, use of multidimensional scales was found to provide a sensitive measure of headache-related functional impairment, especially for detecting clinically meaningful cognitive effects, and for detecting drug versus placebo differences. [source]

Measurement of physical work capacity during arm and shoulder lifting at various shoulder flexion and ad/abduction angles

HUMAN FACTORS AND ERGONOMICS IN MANUFACTURING & SERVICE INDUSTRIES, Issue 2 2003
Jung-Yong Kim
The purpose of this study was to provide information on physical work capacity during arm and shoulder lifting at various shoulder flexion and ad/abduction angles. We measured the maximum voluntary contractions (MVCs) in 20 male participants during controlled one-arm lifting. The lifting involved upward motion of the scapula at various shoulder angles. Simultaneously, the electromyographic (EMG) activity of 3 shoulder muscles and psychophysical workload were also recorded. The various measurements were compared to provide a multidimensional assessment of the physical work capacity of the shoulder at various working angles. In particular, 90 and 120 degrees of flexion, 30 degrees of adduction, and 90 degrees of abduction were found to be the most vulnerable angles based on the measured MVCs. The average root mean square value of the EMG increased most significantly at 90 to 150 degrees of flexion and at 30 and 60 degrees of abduction. Slightly different measurements were compared to validate the results. In addition, a 3-D static biomechanical model was used to show whether the estimated shoulder workload matched the measured physical capacity of the shoulder. In conclusion, these results may help ergonomists to identify shoulder angles associated with a relatively high risk of injury, and to match the workload with the physical capacity of the shoulder. Task-specific information on shoulder work capacity is needed in the manufacturing and shipbuilding industries to protect workers from acute injuries and cumulative trauma disorders of the shoulder. Experimental results provide various data on shoulder work capacity during realistic multijoint arm and shoulder lifting, and should help lead to improvements in workplace ergonomic design. © 2003 Wiley Periodicals, Inc. Hum Factors Man 13: 153,163, 2003. [source]