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Minimum Diameter (minimum + diameter)
Selected AbstractsA quantitative study of the optic nerve in diabetic mutant, Otsuka Long-Evans Tokushima Fatty (OLETF) ratsCONGENITAL ANOMALIES, Issue 4 2001Kazuhiko Sawada ABSTRACT, Optic nerves of the Otsuka Long-Evans Tokushima Fatty (OLETF) rat, an animal model of non-insulin dependent diabetes mellitus, were examined using quantitative stereological procedures. At 67 weeks of age, OLETF rats showed a mild hyperglycemia: their blood glucose level was 196 ± 93 mg/dl, significantly higher than that of non-diabetic control Long-Evans Tokushima Otsuka (LETO) rats (110 ± 24 mg/dl). However, there were no differences in the cross sectional area of optic nerves (the mean minimum diameter), the total number and mean diameter of both myelinated and non-myelinated fibers, or the thickness of the myelin sheath between OLETF and LETO rats. The results suggested that a mild hyperglycemia in OLETF rats could not cause any morphological changes in the optic nerve. [source] Sentinel node in head and neck cancer: Use of size criterion to upstage the no neck in head and neck squamous cell carcinoma,HEAD & NECK: JOURNAL FOR THE SCIENCES & SPECIALTIES OF THE HEAD AND NECK, Issue 2 2007Lee W. T. Alkureishi MBChB Abstract Background. Anatomical imaging tools demonstrate poor sensitivity in head and neck squamous cell carcinoma (HNSCC) patients with clinically node-negative necks (cN0). This study evaluates nodal size as a staging criterion for detection of cervical metastases, utilizing sentinel node biopsy (SNB) and additional pathology (step-serial sectioning, SSS; and immunohistochemistry, IHC). Methods. Sixty-five patients with clinically N0 disease underwent SNB, with a mean of 2.4 nodes excised per patient. Nodes were fixed in formalin, bisected, and measured in 3 axes before hematoxylin-eosin staining. Negative nodes were subjected to SSS and IHC. SNB-positive patients underwent modified radical neck dissection. Results. Maximum diameter was larger in levels II and III (13.1 and 13.2 mm) when compared with level I (10.5 mm; p = .004, p = .018), while minimum diameter was constant. Positive nodes were larger than negative nodes (p = .007), but nodes found positive by SSS/IHC were not significantly larger than negative nodes for either measurement (p = .433). Sensitivity and specificity were poor for all measurements. Conclusions. Nodal size is an inaccurate predictor of nodal metastases and should not be regarded as an accurate means of staging the clinically N0 neck. © 2006 Wiley Periodicals, Inc. Head Neck, 2006 [source] On the construction of maximum residual energy resource broadcast trees with minimum diameter in static ad hoc wireless networksINTERNATIONAL JOURNAL OF COMMUNICATION SYSTEMS, Issue 1 2006Chor Ping Low Abstract Each node in a wireless ad hoc network runs on a local energy source that has a limited energy life span. Thus, energy conservation is a critical issue in such networks. In addition, it is in general desirable to construct routes with low hop counts as a route with a high hop count is more likely to be unstable (because the probability that intermediate nodes will move away is higher). In this paper, we address these two issues concurrently with energy conservation as the primary objective and low hop count as the secondary objective. One way of addressing the energy conservation issue is to construct routes that maximize the minimum residual battery capacity available among all nodes in each route. A broadcast tree with all routes satisfying this condition is referred to as a maximum residual energy resource broadcast tree. A maximum residual energy resource broadcast tree with the least diameter is referred to as a minimum diameter maximum residual energy resource broadcast tree and the problem of constructing such a tree is referred to as the minimum diameter maximum residual energy resource broadcast routing problem (MDMRERBRP). We propose an algorithm for MDMRERBRP and prove that MDMRERBRP is optimally solvable in polynomial time using the proposed algorithm. Copyright © 2005 John Wiley & Sons, Ltd. [source] Ages of rampart craters in equatorial regions on Mars: Implications for the past and present distribution of ground iceMETEORITICS & PLANETARY SCIENCE, Issue 10 2006D. Reiss We measured crater size frequencies on the layered ejecta of rampart craters in three equatorial regions to derive absolute model ages and to constrain the regional volatile history. Nearly all rampart craters in the Xanthe Terra region are ,3.8 Gyr old. This corresponds to the Noachian fluvial activity that region. Rampart crater formation declines in the Hesperian, whereas onset diameters (minimum diameter) increase. No new rampart craters formed after the end of the Hesperian (,3 Gyr). This indicates a lowering of the ground ice table with time in the Xanthe Terra region. Most rampart craters in the Valles Marineris region are around 3.6 Gyr old. Only one large, probably Amazonian-aged (,2.5 Gyr), rampart crater exists. These ages indicate a volatile-rich period in the Early Hesperian and a lowering of the ground ice table with time in the Valles Marineris study region. Rampart craters in southern Chryse Planitia, which are partly eroded by fluvial activity, show ages around 3.9 Gyr. Rampart craters superposed on channels have ages between ,1.5 and ,0.6 Gyr. The onset diameter (3 km at ,1.5 Gyr) in this region may indicate a relatively shallow ground ice table. Loss of volatiles due to diffusion and sublimation might have lowered the ground ice table even in the southern Chryse Planitia region afterwards. In general, our study implies a formation of the smallest rampart craters within and/or shortly after periods of fluvial activity and a subsequent lowering of the ground ice table indicated by increasing onset diameter to the present. These results question the method to derive present equatorial ground ice depths from the onset diameter of rampart craters without information about their formation time. [source] Catheter closure of moderate to large sized patent ductus arteriosus using the simultaneous double or triple coil techniquePEDIATRICS INTERNATIONAL, Issue 5 2001Teiji Akagi AbstractBackground: Although the clinical experience with transcatheter closure of the patent ductus arteriosus using the coils has grown rapidly, one important complication of this procedure using the conventional Gianturco coil was the migration of coils into peripheral vessels. This is especially for patients with a relatively larger size ductus and the risk for such complications could be increased. In this situation, the detachable coil may have some technical benefits to perform coil occlusion and reduce the incidence of complications. Methods: We describe the clinical efficacy of a simultaneous double or triple coil occlusion technique using the Cook detachable coil or bioptome delivered 0.052 inch Gianturco coil to close the ductus arteriosus. This was performed in patients whose ductus diameter was greater than 3.0 mm. Results: From February 1995 to December 2000, 118 patients with patent ductus arteriosus were treated by coil occlusion using Cook detachable coils, of whom 58 patients whose minimum diameter of ductus , 3.0 mm were reviewed. All patients had successful placement of coils. According to the evaluation by color flow mapping, a trivial shunt was observed in 17 patients (29%) within 24 h after the procedure. In 11 out of 17 patients, a residual shunt was not detected 1 month after the procedure. At 6 months after the procedure, the residual shunt was detected only in three patients. Conclusions: Although this study did not calculate the statistical significance between detachable and non-detachable coils in term of occlusion rate, our institutional experience suggests that the simultaneous double or triple coil technique using the detachable or 0.052 inch Gianturco coils can reduce the prevalence of coil migration or complications. [source] Aspects of achondroplasia in the skulls of dwarf transgenic mice: A cephalometric studyTHE ANATOMICAL RECORD : ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY, Issue 3 2006Melissa Wadler Bloom Abstract Achondroplasia, the most common short-limbed dwarfism in humans, results from a single nucleotide substitution in the gene for fibroblast growth factor receptor 3 (FGFR3). FGFR3 regulates bone growth in part via the mitogen-activated protein kinase pathway (MAPK). To examine the role of this pathway in chondrocyte differentiation, a transgenic mouse was generated that expresses a constitutively active mutant of MEK1 in chondrocytes and exhibits dwarfing characteristics typical of human achondroplasia, i.e., shortened axial and appendicular skeletons, mid-facial hypoplasia, and dome-shaped cranium. In this study, cephalometrics of the MEK1 mutant skulls were assessed to determine if the MEK1 mice are a good model of achondroplasia. Skull length, arc of the cranial vault, and area, maximum and minimum diameters of the brain case were measured on digitized radiographs of skulls of MEK1 and control mice. Cranial base and nasal bone length and foramen magnum diameter were measured on midsagittal micro-CT sections. Data were normalized by dividing by the cube root of each animal's weight. Transgenic mice exhibited a domed skull, deficient midface, and (relatively) prognathic mandible and had a shorter cranial base and nasal bone than the wild-type. Skull length was significantly less in transgenic mice, but cranial arc was significantly greater. The brain case was larger and more circular and minimum diameter of the brain case was significantly greater in transgenic mice. The foramen magnum was displaced anteriorly but not narrowed. MEK1 mouse cephalometrics confirm these mice as a model for achondroplasia, demonstrating that the MAP kinase signaling pathway is involved in FGF signaling in skeletal development. © 2006 Wiley-Liss, Inc. [source] The Mechanism of Hearing Loss in Paget's Disease of Bone,THE LARYNGOSCOPE, Issue 4 2004Edwin M. Monsell MD Abstract Objectives/Hypothesis The mechanism of hearing loss (HL) in Paget's disease of bone was investigated. The present study was a systematic, prospective, controlled set of clinical investigations to test the hypothesis that there is a general underlying mechanism of HL in Paget's disease of bone and to gain additional insights into the auditory and otologic dynamics of this disease. Specific questions were 1) whether the mechanism is cochlear or retrocochlear and 2) whether the bone mineral density of the cochlear capsule is related to hearing levels. Study Design Several double-blinded, cross-sectional, prospective, correlational studies were conducted in a population of elderly human subjects with skull involvement with Paget's disease versus a control population of elderly subjects free of Paget's disease. Demographic and clinical data were recorded. Longitudinal observations were made in subjects under treatment. Methods Subjects were recruited from a Paget's disease clinic. Pure-tone auditory thresholds, word recognition, and auditory brainstem responses (ABRs) were recorded. The dimensions of the internal auditory canals were measured using computed tomographic (CT) images and digital image analysis. The precision, accuracy, and temporal stability of methods to measure the bone mineral density of the cochlear capsule and an adjacent area of nonotic capsule bone were validated and applied. Correlations were sought between hearing levels and cochlear capsule bone mineral density. Results ABRs were recorded in 64 ears with radiographically confirmed Paget's disease involving the skull. Responses were absent in eight ears, all of which had elevated high pure-tone thresholds. ABRs were interpreted as normal in 56 ears; none were abnormal. The mid-length diameter and minimum diameter of the internal auditory canal of 68 temporal bones from subjects with Paget's disease were found to have no statistically significant relationship to hearing thresholds. The Pearson product-moment correlation coefficients (age- and sex-adjusted) in the group with Paget's disease involving the temporal bone were ,0.63 for left ears and ,0.73 for right ears for high-frequency air conduction pure-tone thresholds (mean of 1, 2, and 4 kHz) versus cochlear capsule density. Correlation coefficients (age- and sex-adjusted) between cochlear capsule density and air-bone gap (mean at 0.5 and 1 kHz) for the affected group were ,0.67 for left ears and ,0.63 for right ears. All correlations between hearing thresholds and cochlear capsule density in pagetic subjects were significant at P < .001. The regressions were consistent throughout the ranges of hearing level. There were no significant correlations between cochlear capsule mean density and hearing level in the volunteer subjects. Conclusions The evidence supports the existence of a general, underlying, cochlear mechanism of pagetic HL that is closely related to loss of bone mineral density in the cochlear capsule. This mechanism accounts well for both the high-frequency sensorineural HL and the air-bone gap. Early identification, radiographic diagnosis of temporal bone involvement, and vigorous treatment with third-generation bisphosponates are important to limit the development and progression of pagetic HL. [source] Beyond Reaping the First Harvest: Management Objectives for Timber Production in the Brazilian AmazonCONSERVATION BIOLOGY, Issue 4 2007DANIEL J. ZARIN manejo de bosques; producción sostenida; sustentabilidad; tala de impacto reducido Abstract:,Millions of hectares of future timber concessions are slated to be implemented within large public forests under the forest law passed in 2006 by the Brazilian Congress. Additional millions of hectares of large, privately owned forests and smaller areas of community forests are certified as well managed by the Forest Stewardship Council, based on certification standards that will be reviewed in 2007. Forest size and ownership are two key factors that influence management objectives and the capacity of forest managers to achieve them. Current best ecological practices for timber production from Brazil's native Amazon forests are limited to reduced-impact logging (RIL) systems that minimize the environmental impacts of harvest operations and that obey legal restrictions regarding minimum diameters, rare species, retention of seed trees, maximum logging intensity, preservation of riparian buffers, fire protection, and wildlife conservation. Compared with conventional, predatory harvesting that constitutes >90% of the region's timber production, RIL dramatically reduces logging damage and helps maintain forest cover and the presence of rare tree species, but current RIL guidelines do not assure that the volume of timber removed can be sustained in future harvests. We believe it is counterproductive to expect smallholders to subscribe to additional harvest limitations beyond RIL, that larger private forested landholdings managed for timber production should be sustainable with respect to the total volume of timber harvested per unit area per cutting cycle, and that large public forests should sustain volume production of individual harvested species. These additional requirements would improve the ecological sustainability of forest management and help create a stable forest-based sector of the region's economy, but would involve costs associated with lengthened cutting cycles, reduced harvest intensities, and/or postharvest silviculture to promote adequate growth and regeneration. Resumen:,Bajo la nueva ley forestal aprobada en 2006 por el Congreso Brasileño, millones de hectáreas de bosques públicos están destinadas a constituir futuras concesiones madereras. Millones de hectáreas adicionales de extensos bosques privados y áreas reducidas de bosques comunitarios están certificadas por el Forest Stewardship Council por su buen manejo, con base en estándares de certificación que serán revisados en 2007. La extensión y tenencia del bosque son dos factores clave que influyen en los objetivos de manejo y en la capacidad de los manejadores para alcanzarlos. Las mejores prácticas ecológicas actuales para la producción de madera en los bosques de la Amazonía Brasileña están limitadas a sistemas de tala de impacto reducido (TIR) que minimizan los impactos ambientales de las operaciones de cosecha y que obedecen restricciones legales en relación con los diámetros mínimos, las especies raras, la retención de árboles semilla, la máxima intensidad de tala, la preservación de amortiguamientos ribereños, la protección del fuego y la conservación de vida silvestre. En comparación con la cosecha convencional, depredadora, mediante la cual se obtiene >90% de la producción de madera en la región, la TIR dramáticamente reduce el daño y ayuda a mantener la cobertura del bosque y la presencia de especies de árboles raras, pero los actuales lineamientos de TIR no aseguran que el volumen de madera removida pueda ser sostenido en futuras cosechas. Consideramos que es contraproducente esperar que los pequeños propietarios suscriban límites a la cosecha más allá de la TIR; que los bosques privados manejados para la producción de madera debieran ser sustentables respecto al volumen total de madera cosechada por unidad de área por ciclo de corte; y que los bosques públicos deberían sustentar el volumen de producción de especies individuales. Estos requerimientos adicionales mejorarían la sustentabilidad ecológica del manejo de bosques y ayudaría a crear un sector forestal estable en la economía regional, pero implicarían costos asociados con la prolongación de los ciclos de corte, la reducción de las intensidades de cosecha y/o la silvicultura postcosecha para promover el crecimiento adecuado y la regeneración. [source] Aspects of achondroplasia in the skulls of dwarf transgenic mice: A cephalometric studyTHE ANATOMICAL RECORD : ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY, Issue 3 2006Melissa Wadler Bloom Abstract Achondroplasia, the most common short-limbed dwarfism in humans, results from a single nucleotide substitution in the gene for fibroblast growth factor receptor 3 (FGFR3). FGFR3 regulates bone growth in part via the mitogen-activated protein kinase pathway (MAPK). To examine the role of this pathway in chondrocyte differentiation, a transgenic mouse was generated that expresses a constitutively active mutant of MEK1 in chondrocytes and exhibits dwarfing characteristics typical of human achondroplasia, i.e., shortened axial and appendicular skeletons, mid-facial hypoplasia, and dome-shaped cranium. In this study, cephalometrics of the MEK1 mutant skulls were assessed to determine if the MEK1 mice are a good model of achondroplasia. Skull length, arc of the cranial vault, and area, maximum and minimum diameters of the brain case were measured on digitized radiographs of skulls of MEK1 and control mice. Cranial base and nasal bone length and foramen magnum diameter were measured on midsagittal micro-CT sections. Data were normalized by dividing by the cube root of each animal's weight. Transgenic mice exhibited a domed skull, deficient midface, and (relatively) prognathic mandible and had a shorter cranial base and nasal bone than the wild-type. Skull length was significantly less in transgenic mice, but cranial arc was significantly greater. The brain case was larger and more circular and minimum diameter of the brain case was significantly greater in transgenic mice. The foramen magnum was displaced anteriorly but not narrowed. MEK1 mouse cephalometrics confirm these mice as a model for achondroplasia, demonstrating that the MAP kinase signaling pathway is involved in FGF signaling in skeletal development. © 2006 Wiley-Liss, Inc. [source] Canine Spinal Cord Neuron and Axon Myelin Sheath MorphometryANATOMIA, HISTOLOGIA, EMBRYOLOGIA, Issue 5 2006A. C. De Francischini Carvalho Summary This inedited morphometric study has been developed from healthy canine spinal cord neuron cytoplasm and nucleus, and white matter axonal myelin sheath, from cervical, thoracic and lumbar regions. For the morphometric study, the parameters were area, perimeter, maximum and minimum diameters and roundness for neurons and myelin thickness for axon. For each parameter, 300 neurons were analysed. The results revealed that lumbar neurons had the highest mean values for the analysed parameters, indicating the presence of large neurons in this region, with large axons as a result of myelin thickness, which is proportional to axon calibre. We conclude that these morphometric results can contribute for the establishment of normal patterns, for canine spinal cord cervical, thoracic and lumbar segments. [source] | |||||||||||||