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Microwave Irradiation Conditions (microwave + irradiation_condition)
Selected Abstracts4- exo - dig Cyclocarbopalladation: A Straightforward Synthesis of Cyclobutanediols from Acyclic ,-Bromopropargylic Diols under Microwave Irradiation Conditions,EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 6 2006Christophe Bour Abstract Treatment of acyclic ,-bromopropargylic diols with tributylstannylated alkynes under palladium catalysis and microwave irradiation conditions gives high yields of the bis(alkylidene)cyclobutanediol derivatives and cyclobutenediols through an efficient 4- exo - dig cyclocarbopalladation. The cyclization is general with a wide variety of alkyne derivatives and gives access to new cyclobutane ring systems bearing one exocyclic double bond and one eneyne substituent as well as bicyclic dienes sharing a common double bond that may be of interest for further elaborations of complex molecules. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006) [source] ChemInform Abstract: An Efficient and Greener Approach to the Synthesis of 3,5-Dicyanopyridin-2(1H)-one Derivatives in Aqueous Media under Microwave Irradiation Conditions.CHEMINFORM, Issue 4 2008Runhong Jia Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] A Simple and Efficient Method for the Synthesis of Novel Trifluoromethyl Benzimidazoles under Microwave Irradiation Conditions.CHEMINFORM, Issue 47 2002G. Venkat Reddy Abstract For Abstract see ChemInform Abstract in Full Text. [source] The Synthesis of 1-Arylseleno-3-alkoxy-2-propanols under Microwave Irradiation Conditions.CHEMINFORM, Issue 44 2002Jin-Xian Wang No abstract is available for this article. [source] ChemInform Abstract: Copper-Catalyzed Cross-Coupling Reaction under Microwave Irradiation Conditions.CHEMINFORM, Issue 17 2001Jin-Xian Wang Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] 4- exo - dig Cyclocarbopalladation: A Straightforward Synthesis of Cyclobutanediols from Acyclic ,-Bromopropargylic Diols under Microwave Irradiation Conditions,EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 6 2006Christophe Bour Abstract Treatment of acyclic ,-bromopropargylic diols with tributylstannylated alkynes under palladium catalysis and microwave irradiation conditions gives high yields of the bis(alkylidene)cyclobutanediol derivatives and cyclobutenediols through an efficient 4- exo - dig cyclocarbopalladation. The cyclization is general with a wide variety of alkyne derivatives and gives access to new cyclobutane ring systems bearing one exocyclic double bond and one eneyne substituent as well as bicyclic dienes sharing a common double bond that may be of interest for further elaborations of complex molecules. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006) [source] Microwave-Assisted Dimroth Rearrangement of Thiazines to Dihydropyrimidinethiones: Synthetic and Mechanistic AspectsMOLECULAR INFORMATICS, Issue 5-6 2006Abstract The Dimroth rearrangement of a set of substituted 2-amino-6H -1,3-thiazines into 3,4-dihydropyrimidine-2-thiones was investigated. The rearrangements were carried out under microwave irradiation conditions in batch or continuous flow format, employing either toluene or 1-methyl-2-pyrrolidone as solvent. Thiazines bearing an ester group at the C5 position rearranged at a considerably higher temperature than derivatives without substituents at this position into the corresponding pyrimidinethiones. This strictly thermal rearrangement was studied in detail using differential scanning calorimetry and density functional theory computational methods. The reaction pathway involves a zwitterionic intermediate. [source] Synthesis and In-Vitro Cytotoxicity Evaluation of Novel Naphtindolizinedione Derivatives, Part II: Improved Activity for Aza-AnaloguesARCHIV DER PHARMAZIE, Issue 2 2009Andrea Defant Abstract Our previous investigation on potential antitumor agents now got enriched by the evaluation of in-vitro activity against a full panel of NCI cancer cell lines for five new compounds. The concurrent presence in the molecular structure of a nitrogen atom in the aromatic system and a N,N -dimethylaminoethyl amide chain play a decisive role to enhance cytotoxicity. The N,N -anti compound 14 shows a higher activity than its N,N -syn isomer, exhibiting the best selective inhibition against the melanoma MALME-3M cell line, with a GI50 -value (= 30 nM) corresponding to a 330-fold increase in activity compared to the corresponding deaza-analogue. Compound 14 is efficiently synthesized by aminolysis of the ester obtained as a single regio-isomer by an one-pot three-component procedure involving metal-assisted cyclization under microwave irradiation conditions. [source] ChemInform Abstract: Metal-Catalyzed Reactions Between 2-Azabicyclo[2.2.1]hept-5-en-3-ones and Arylboronic Acids.CHEMINFORM, Issue 42 2010Takumi Abe Abstract Under microwave irradiation conditions, catalytic amounts of Cu(II) are sufficient to catalyze the N-arylation of bicycle (I) and analogues, whereas in the presence of a rhodium catalyst C-arylation occurs. [source] ChemInform Abstract: PEG-400 Catalyzed Reaction of the Synthesis of 2,4,6-Triarylpyridines and Crystal Structure of 2,4,6-Tris(4,-chlorophenyl)pyridine.CHEMINFORM, Issue 34 2010Qingpeng He Abstract A new and operationally simple procedure for the one-pot synthesis of triarylpyridines (III) mediated by PEG-400 under solvent-free and microwave irradiation conditions is described. [source] Screening of a Modular Sugar-Based Phosphite,Oxazoline Ligand Library in Asymmetric Pd-Catalyzed Heck ReactionsCHEMISTRY - A EUROPEAN JOURNAL, Issue 12 2007Yvette Mata Abstract We have synthesised a library of phosphite,oxazoline ligands derived from readily available D -glucosamine. These ligands have been successfully screened in the palladium-catalysed Heck reaction of several substrates with high regio- (up to 99,%) and enantioselectivities (ee's up to 99,%) as well as with improved activities under standard thermal conditions. The results indicate that the catalytic performance is highly affected by the oxazoline and biarylphosphite substituents and the axial chirality of the biaryl moiety of the ligand. The Heck reactions were also performed under microwave irradiation conditions, allowing a considerably shorter reaction time (full conversion in minutes) maintaining the excellent regio- and enantioselectivities. [source] | ||||||||||