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Many Regions (many + regions)
Selected AbstractsA PERSPECTIVE ON PHOTOSYNTHESIS IN THE OLIGOTROPHIC OCEANS: HYPOTHESES CONCERNING ALTERNATE ROUTES OF ELECTRON FLOW,JOURNAL OF PHYCOLOGY, Issue 4 2010Arthur R. Grossman Many regions of the open, oligotrophic oceans are depleted of nutrients, especially nitrogen and iron. The biogenesis and the functioning of the photosynthetic apparatus may be specialized and tailored to the various marine habitats. In this minireview, we discuss some new findings with respect to photosynthetic processes in the oceans. We focus on findings that suggest that some cyanobacteria may route electrons derived from the splitting of H2O to the reduction of O2 and H+ in a water-to-water cycle, and that other cyanobacteria that fix nitrogen during the day are likely missing PSII and enzymes involved in the fixation of inorganic carbon. Both of these proposed "variant" forms of photosynthetic electron flow provide new insights into ways in which marine phytoplankton satisfy their energetic and nutritive requirements. [source] ETHICS BEYOND BORDERS: HOW HEALTH PROFESSIONALS EXPERIENCE ETHICS IN HUMANITARIAN ASSISTANCE AND DEVELOPMENT WORKDEVELOPING WORLD BIOETHICS, Issue 2 2008MATTHEW R. HUNT ABSTRACT Health professionals are involved in humanitarian assistance and development work in many regions of the world. They participate in primary health care, immunization campaigns, clinic- and hospital-based care, rehabilitation and feeding programs. In the course of this work, clinicians are frequently exposed to complex ethical issues. This paper examines how health workers experience ethics in the course of humanitarian assistance and development work. A qualitative study was conducted to consider this question. Five core themes emerged from the data, including: tension between respecting local customs and imposing values; obstacles to providing adequate care; differing understandings of health and illness; questions of identity for health workers; and issues of trust and distrust. Recommendations are made for organizational strategies that could help aid agencies support and equip their staff as they respond to ethical issues. [source] Evidence for neural stem cells in the medaka optic tectum proliferation zones,DEVELOPMENTAL NEUROBIOLOGY, Issue 10 2010Alessandro Alunni Abstract Few adult neural stem cells have been characterized in vertebrates. Although teleosts continually generate new neurons in many regions of the brain after embryogenesis, only two types of neural stem cells (NSCs) have been reported in zebrafish: glial cells in the forebrain resembling mammalian NSCs, and neuroepithelial cells in the cerebellum. Here, following our previous studies on dividing progenitors (Nguyen et al. [1999]: J Comp Neurol 413:385,404.), we further evidenced NSCs in the optic tectum (OT) of juvenile and adult in the medaka, Oryzias latipes. To detect very slowly cycling progenitors, we did not use the commonly used BrdU/PCNA protocol, in which PCNA may not be present during a transiently quiescent state. Instead, we report the optimizations of several protocols involving long subsequent incubations with two thymidine analogs (IdU and CldU) interspaced with long chase times between incubations. These protocols allowed us to discriminate and localize fast and slow cycling cells in OT of juvenile and adult in the medaka. Furthermore, we showed that adult OT progenitors are not glia, as they express neither brain lipid-binding protein (BLBP) nor glial fibrillary acidic protein (GFAP). We also showed that expression of pluripotency-associated markers (Sox2, Musashi1 and Bmi1) colocalized with OT progenitors. Finally, we described the spatio-temporally ordered population of NSCs and progenitors in the medaka OT. Hence, the medaka appears as an invaluable model for studying neural progenitors that will open the way to further exciting comparative studies of neural stem cells in vertebrates. © 2010 Wiley Periodicals, Inc. Develop Neurobiol 70: 693,713, 2010 [source] The migratory behavior of immature enteric neuronsDEVELOPMENTAL NEUROBIOLOGY, Issue 1 2009M.M. Hao Abstract While they are migrating caudally along the developing gut, around 10%,20% of enteric neural crest-derived cells start to express pan-neuronal markers and tyrosine hydroxylase (TH). We used explants of gut from embryonic TH-green fluorescence protein (GFP) mice and time-lapse microscopy to examine whether these immature enteric neurons migrate and their mode of migration. In the gut of E10.5 and E11.5 TH-GFP mice, around 50% of immature enteric neurons (GFP+ cells) migrated, with an average speed of around 15 ,m/h. This is slower than the speed at which the population of enteric neural crest-derived cells advances along the developing gut, and hence neuronal differentiation seems to slow, but not necessarily halt, the caudal migration of enteric neural crest cells. Most migrating immature enteric neurons migrated caudally by extending a long-leading process followed by translocation of the cell body. This mode of migration is different from that of non-neuronal enteric neural crest-derived cells and neural crest cells in other locations, but resembles that of migrating neurons in many regions of the developing central nervous system (CNS). In migrating immature enteric neurons, a swelling often preceded the movement of the nucleus in the direction of the leading process. However, the centrosomal marker, pericentrin, was not localized to either the leading process or swelling. This seems to be the first detailed report of neuronal migration in the developing mammalian peripheral nervous system. © 2008 Wiley Periodicals, Inc. Develop Neurobiol, 2009. [source] Association of British Clinical Diabetologists (ABCD) and Diabetes-UK survey of specialist diabetes services in the UK, 2006.DIABETIC MEDICINE, Issue 6 2008Abstract Aims To identify the views and working practices of consultant diabetologists in the UK in 2006,2007, the current provision of specialist services, and to examine changes since 2000. Methods All 592 UK consultant diabetologists were invited to participate in an on-line survey. Quantitative and qualitative analyses of responses were undertaken. A composite ,well-resourced service score' was calculated. In addition to an analysis of all respondents, a sub-analysis was undertaken, comparing localities represented both in 2006/2007 and in 2000. Results In 2006/2007, a 49% response rate was achieved, representing 50% of acute National Health Service Trusts. Staffing levels had improved, but remained below recommendations made in 2000. Ten percent of specialist services were still provided by single-handed consultants, especially in Northern Ireland (in 50% of responses, P = 0.001 vs. other nations). Antenatal, joint adult,paediatric and ophthalmology sub-specialist diabetes services and availability of biochemical tests had improved since 2000, but access to psychology services had declined. Almost 90% of consultants had no clinical engagement in providing community diabetes services. The ,well-resourced service score' had not improved since 2000. There was continued evidence of disparity in resources between the nations (lowest in Wales and Northern Ireland, P = 0.007), between regions in England (lowest in the East Midlands and the Eastern regions, P = 0.028), and in centres with a single-handed consultant service (P = 0.001). Job satisfaction correlated with well-resourced service score (P = 0.001). The main concerns and threats to specialist services were deficiencies in psychology access, inadequate staffing, lack of progress in commissioning, and the detrimental impact of central policy on specialist services. Conclusions There are continued disparities in specialist service provision. Without effective commissioning and adequate specialist team staffing, integrated diabetes care will remain unattainable in many regions, regardless of reconfigurations and alternative service models. [source] Pigs, presses and pastoralism: farming in the fifth to sixth centuries ADEARLY MEDIEVAL EUROPE, Issue 1 2009Tamara Lewit The fifth to sixth centuries were a time of significant change in rural settlement, land use, production levels and productive technology in many regions. Archaeological and related discoveries suggest that in western Europe, specialized market- and state-oriented production gave way to mixed animal husbandry and diversified farming more suited to local terrains. This was accompanied by a widespread transformation of rural settlement. In contrast, the eastern Mediterranean experienced rural settlement expansion, intensification of land use, increased market-oriented agricultural production, and a significant change in oil and wine press technology. These changes seem to reflect the socio-political context in both east and west during this pivotal period. [source] Regional Income Inequality and International TradeECONOMIC GEOGRAPHY, Issue 3 2004Julie A. Silva Abstract: This study investigates the effects of trade on income inequality across regions in the United States. Using both structural and price-based measures of regional trade involvement, we evaluate the effects of trade on inequality within and across states, the metropolitan and nonmetropolitan portions of the states, and the major census regions. Across all states and metropolitan and nonmetropolitan areas, we found that trade affects inequality primarily via import and export prices. In contrast to our expectations, however, a weaker dollar,more expensive imports and cheaper exports,is associated with the worsening of a state's position relative to other states and greater inequality within the state. Across the census regions, both our price and orientation measures had significant effects, but the direction of these effects varied by region. Whereas many regions benefited from cheaper imports, states in regions that are traditionally home to low-wage sectors, including the Southeast and South Central regions, were made relatively worse off by lower import prices and by greater orientation toward import-competing goods. Our findings reinforce notions about the uneven impacts of globalization and suggest that policy measures are needed to ensure that both the benefits and costs of involvement in international trade are shared across regions. [source] Mercury-induced reproductive impairment in fish,,ENVIRONMENTAL TOXICOLOGY & CHEMISTRY, Issue 5 2009Kate L. Crump Abstract Mercury is a potent neurotoxin, and increasing levels have led to concern for human and wildlife health in many regions of the world. During the past three decades, studies in fish have examined the effects of sublethal mercury exposure on a range of endpoints within the reproductive axis. Mercury studies have varied from highly concentrated aqueous exposures to ecologically relevant dietary exposures using levels comparable to those currently found in the environment. This review summarizes data from both laboratory and field studies supporting the hypothesis that mercury in the aquatic environment impacts the reproductive health of fish. The evidence presented suggests that the inhibitory effects of mercury on reproduction occur at multiple sites within the reproductive axis, including the hypothalamus, pituitary, and gonads. Accumulation of mercury in the fish brain has resulted in reduced neurosecretory material, hypothalamic neuron degeneration, and alterations in parameters of monoaminergic neurotransmission. At the level of the pituitary, mercury exposure has reduced and/or inactivated gonadotropin-secreting cells. Finally, studies have examined the effects of mercury on the reproductive organs and demonstrated a range of effects, including reductions in gonad size, circulating reproductive steroids, gamete production, and spawning success. Despite some variation between studies, there appears to be sufficient evidence from laboratory studies to link exposure to mercury with reproductive impairment in many fish species. Currently, the mechanisms underlying these effects are unknown; however, several physiological and cellular mechanisms are proposed within this review. [source] Agricultural pesticides and selected degradation products in five tidal regions and the main stem of Chesapeake Bay, USAENVIRONMENTAL TOXICOLOGY & CHEMISTRY, Issue 12 2007Laura L. McConnell Abstract Nutrients, sediment, and toxics from water sources and the surrounding airshed are major problems contributing to poor water quality in many regions of the Chesapeake Bay, an important estuary located in the mid-Atlantic region of the United States. During the early spring of 2000, surface water samples were collected for pesticide analysis from 18 stations spanning the Chesapeake Bay. In a separate effort from July to September of 2004, 61 stations within several tidal regions were characterized with respect to 21 pesticides and 11 of their degradation products. Three regions were located on the agricultural Delmarva Peninsula: The Chester, Nanticoke, and Pocomoke Rivers. Two regions were located on the more urban western shore: The Rhode and South Rivers and the Lower Mobjack Bay, including the Back and Poquoson Rivers. In both studies, herbicides and their degradation products were the most frequently detected chemicals. In 2000, atrazine and metolachlor were found at all 18 stations. In 2004, the highest parent herbicide concentrations were found in the upstream region of Chester River. The highest concentration for any analyte in these studies was for the ethane sulfonic acid of metolachlor (MESA) at 2,900 ng/L in the Nanticoke River. The degradation product MESA also had the greatest concentration of any analyte in the Pocomoke River (2,100 ng/L) and in the Chester River (1,200 ng/L). In the agricultural tributaries, herbicide degradation product concentrations were more strongly correlated with salinity than the parent herbicides. In the two nonagricultural watersheds on the western shore, no gradient in herbicide concentrations was observed, indicating the pesticide source to these areas was water from the Bay main stem. [source] Six Ages towards a Learning Region , A RetrospectiveEUROPEAN JOURNAL OF EDUCATION, Issue 3 2010NORMAN LONGWORTH Learning Cities and Learning Regions are terms now in common use as a result of the growing importance of lifelong learning concepts to the economic, social and environmental future of people and places. Why ,learning' regions? Why not intelligent, creative, clever, smart or knowledge regions? In truth, all of these can, and some do, also exist, but we argue that this is not a semantic debate. The basis of intelligence, smartness, cleverness, creativity and knowledge is effective learning and its intelligent application in creating a better future. We can, we believe, only learn our way into the future and the same is true, in developmental terms, of cities, towns, regions and communities. What therefore is a learning region? Definitions tend to differ according to perception, situation, occupation and objective. Where the focus is on technology a learning region will emphasise the advantages of hi-tech for the development of a physical infrastructure that will assist regeneration and be useful for more efficient behaviour and learning by people and organisations. Hence the growth of ,smart cities,' mainly in North America. Where it is on employment, employability, organisational management and training for industry, the development of human and social capital for economic gain and competitive edge tends to predominate. Most regions concentrate on this aspect. Where the motivation is based on the use of valuable resources, it will concentrate on volunteering, active citizenship and the building of social capital. Such an approach is not well developed in many regions and the optimum balance between economic, community and personal growth is poorly understood. Where the goal is the competent use of organisational potential a learning region will mobilise all its stakeholder institutions as partners in the service of the region as a whole. Here, very little is understood or implemented. This article argues that all of these approaches and others in the fields of environment, personal and cultural growth, innovation, diversity and communication are a holistic part and parcel of learning region development. Its meaning and its characteristics will become clear as it charts the development of ideas about learning regions, particularly those that have occurred during the past 20 years. It suggests the existence of a paradigm shift at work , the age of education and training, which has served us well in the late 20th century in satisfying the needs of a growing, upwardly mobile proportion of the population, has now given way to the era of lifelong learning, in which the means, the tools and techniques are employed to target and motivate everyone in a city, town or region. Those regions that achieve this nirvana will be the winners in the apparent paradox that intelligent local action leads to success in a globalised world, a version of the concept of ,glocalisation' coined by Robertson (1995). [source] Evidence for the involvement of purinergic P2X7 receptors in outer retinal processingEUROPEAN JOURNAL OF NEUROSCIENCE, Issue 1 2006Theresa Puthussery Abstract Extracellular ATP mediates fast excitatory neurotransmission in many regions of the central nervous system through activation of P2X receptors. Although several P2X receptor subunits have been identified in the mammalian retina, little is known about the functional role of these receptors in retinal signalling. The purpose of the present study was to investigate whether purinergic P2X7 receptors are involved in outer retinal processing by assessing receptor localization, degradation of extracellular ATP and the effect of functional activation of P2X7 receptors on the electroretinogram (ERG). Using light and electron microscopy, we demonstrated that P2X7 receptors are expressed postsynaptically on horizontal cell processes as well as presynaptically on photoreceptor synaptic terminals in both the rat and marmoset retina. Using an enzyme cytochemical method, we showed that ecto-ATPases are active in the outer plexiform layer of the rat retina, providing a mechanism by which purinergic synaptic transmission can be rapidly terminated. Finally, we evaluated the role of P2X7 receptors in retinal function by assessing changes to the ERG response of rats after intravitreal delivery of the P2X7 receptor agonist benzoyl benzoyl ATP (BzATP). Intravitreal injection of BzATP resulted in a sustained increase (up to 58%) in the amplitude of the photoreceptor-derived a-wave of the ERG. In contrast, BzATP caused a transient reduction in the rod- and cone-derived postreceptoral responses. These results provide three lines of evidence for the involvement of extracellular purines in outer retinal processing. [source] Cloning, distribution and functional analysis of the type III sodium channel from human brainEUROPEAN JOURNAL OF NEUROSCIENCE, Issue 12 2000Yu Hua Chen Abstract The type III voltage-gated sodium channel was cloned from human brain. The full-length cDNA has 89% identity with rat type III, and the predicted protein (1951 amino acids) has 55 differences. The expression pattern of human type III mRNA was determined in adult brain tissue and, in contrast to rat, was detected in many regions, including caudate nucleus, cerebellum, hippocampus and frontal lobe. The human type III channel was stably expressed in Chinese hamster ovary (CHO) cells and its biophysical properties compared to the human type II channel using identical conditions. The voltage dependence and kinetics of activation were found to be similar to that of type II. The kinetics of inactivation of the two human subtypes were also similar. However, type III channels inactivated at more hyperpolarized potentials and were slower to recover from inactivation than type II. When expressed in human embryonic kidney (HEK293T) cells, type III channels produced currents with a prominent persistent component, which were similar to those reported for rat type II [Ma et al. (1997) Neuron, 19, 443,452]. However, unlike type II, this was prominent even in the absence of coexpressed G-proteins, suggesting type III may adopt this gating mode more readily. The distinct properties of the channel, together with its wide distribution in adult brain, suggest that in humans, type III may have important physiological roles under normal, and perhaps also pathological conditions. [source] Organic matter quality of a forest soil subjected to repeated drying and different re-wetting intensitiesEUROPEAN JOURNAL OF SOIL SCIENCE, Issue 2 2010A. Schmitt Extended drought periods followed by heavy rainfall may increase in many regions of the Earth, but the consequences for the quality of soil organic matter and soil microbial communities are poorly understood. Here, we investigated the effect of repeated drying and re-wetting on microbial communities and the quality of particulate and dissolved organic matter in a Haplic Podzol from a Norway spruce stand. After air-drying, undisturbed soil columns were re-wetted at different intensities (8, 20 and 50 mm per day) and time intervals, so that all treatments received the same amount of water per cycle (100 mm). After the third cycle, SOM pools of the treatments were compared with those of non-dried control columns. Lignin phenols were not systematically affected in the O horizons by the treatments whereas fewer lignin phenols were found in the A horizon of the 20- and 50-mm treatments. Microbial biomass and the ratio of fungi to bacteria were generally not altered, suggesting that most soil microorganisms were well adapted to drying and re-wetting in this soil. However, gram-positive bacteria and actinomycetes were reduced whereas gram-negative bacteria and protozoa were stimulated by the treatments. The increase in the (cy 17: 0 + cy 19: 0)/(16:1,7c + 18:1,7c) ratio indicates physiological or nutritional stress for the bacterial communities in the O, A and B horizons with increasing re-wetting intensity. Drying and re-wetting reduced the amount of hydrolysable plant and microbial sugars in all soil horizons. However, CO2 and dissolved organic carbon fluxes could not explain these losses. We postulate that drying and re-wetting triggered chemical alterations of hydrolysable sugar molecules in organic and mineral soil horizons. [source] An Approximation for the Rank Adjacency Statistic for Spatial Clustering with Sparse DataGEOGRAPHICAL ANALYSIS, Issue 1 2001John Paul Ekwaru The rank adjacency statistic D provides a simple method to assess regional clustering. It is defined as the weighted average absolute difference in ranks of the data, taken over all possible pairs of adjacent regions. In this paper the usual normal approximation to the D statistic is found to give inaccurate results if the data are sparse and some regions have tied ranks. Adjusted formulae for the moments of D that allow for the existence of ties are derived. An example of analyses of sparse mortality data (with many regions having no deaths, and hence tied ranks) showed satisfactory agreement between the adjusted formulae and the empirical distribution of the D statistic. We conclude that the D statistic, when used with adjusted moments, provides a valid approximate method to evaluate spatial clustering, even in sparse data situations. [source] Pan Evaporation Trends and the Terrestrial Water Balance.GEOGRAPHY COMPASS (ELECTRONIC), Issue 2 2009Pan evaporation is just that , it is the evaporation rate of water from a small dish located at the ground-surface. Pan evaporation is a measure of the evaporative demand over terrestrial surfaces. Declines in pan evaporation have now been reported in many regions of the world. The trends vary from one pan to the next, but when averaged over many pans, they are typically in the range of ,1 to ,4 mm a,2 (mm per annum per annum). In energetic terms, a trend of ,2 mm a,2 is equivalent to ,0.16 W m,2 a,1 and over 30 years this is a change of ,4.8 W m,2. For comparison, the top-of-atmosphere forcing due to doubled CO2 is estimated by the Intergovernmental Panel on Climate Change (IPCC) to be ~3.7 W m,2. Hence, the magnitude of the pan evaporation trend is large. What is of even greater interest is the direction , a decline , given the well-established warming of the last 30,50 years. In this article, the first in a two part series, we describe the underlying principles in using and interpreting pan evaporation data and then summarise the reported observations from different countries. In the second article, we describe the interpretation of the trends in terms of changes in the terrestrial water balance. [source] Spring phenology in boreal Eurasia over a nearly century time scaleGLOBAL CHANGE BIOLOGY, Issue 3 2008NICOLAS DELBART Abstract It has been widely reported that tree leaves have tended to appear earlier in many regions of the northern hemisphere in the last few decades, reflecting climate warming. Satellite observations revealed an 8-day advance in leaf appearance date between 1982 and 1991 in northern latitudes. In situ observations show that leaf appearance dates in Europe have advanced by an average of 6.3 days from 1959 to 1996. Modelling of leaf appearance on the basis of temperature also shows a marked advance in temperate and boreal regions from 1955 to 2002. However, before 1955, reported studies of phenological variations are restricted to local scale. Modelling, ground observations and satellite observations are here combined to analyse phenological variations in Eurasian taiga over nearly a century. The trend observed by remote sensing consists mainly in a shift at the end of the 1980s, reflecting a shift in winter and spring temperature. In western boreal Eurasia, a trend to earlier leaf appearance is evident since the mid-1930s, although it is discontinuous. In contrast, the strong advance in leaf appearance detected over Central Siberia using satellite data in 1982,1991 is strengthened by late springs in 1983,1984; moreover, in this region the green-up timing has displayed successive trends with opposite signs since 1920. Thus, such strong trend is not unusual if considered locally. However, the recent advance is unique in simultaneously affecting most of the Eurasian taiga, the leaf appearance dates after 1990 being the earliest in nearly a century in most of the area. [source] A regional frequency analysis of United Kingdom extreme rainfall from 1961 to 2000INTERNATIONAL JOURNAL OF CLIMATOLOGY, Issue 11 2003H. J. Fowler Abstract Multi-day rainfall events are an important cause of recent severe flooding in the UK, and any change in the magnitude of such events may have severe impacts upon urban structures such as dams, urban drainage systems and flood defences and cause failures to occur. Regional pooling of 1-, 2-, 5- and 10-day annual maxima for 1961 to 2000 from 204 sites across the UK is used in a standard regional frequency analysis to produce generalized extreme value growth curves for long return-period rainfall events for each of nine defined climatological regions. Temporal changes in 1-, 2-, 5- and 10-day annual maxima are examined with L-moments using both a 10 year moving window and the fixed decades of 1961,70, 1971,80, 1981,90 and 1991,2000. A bootstrap technique is then used to assess uncertainty in the fitted decadal growth curves and to identify significant trends in both distribution parameters and quantile estimates. There has been a two-part change in extreme rainfall event occurrence across the UK from 1961 to 2000. Little change is observed at 1 and 2 days duration, but significant decadal-level changes are seen in 5- and 10-day events in many regions. In the south of the UK, growth curves have flattened and 5- and 10-day annual maxima have decreased during the 1990s. However, in the north, the 10-day growth curve has steepened and annual maxima have risen during the 1990s. This is particularly evident in Scotland. The 50 year event in Scotland during 1961,90 has become an 8-year, 11-year and 25-year event in the East, South and North Scotland pooling regions respectively during the 1990s. In northern England the average recurrence interval has also halved. This may have severe implications for design and planning practices in flood control. Copyright © 2003 Royal Meteorological Society [source] Effects of the North Atlantic oscillation on the probability for climatic categories of local monthly rainfall in southern SpainINTERNATIONAL JOURNAL OF CLIMATOLOGY, Issue 4 2003D. Muñoz-Díaz Abstract In many regions of the world, planning agricultural and water management activities is usually done based on probabilities for seasonal or monthly rainfall, for specified intervals of values. These intervals of rainfall amounts are commonly grouped into three categories: drought, normal rainfall, and abundant rainfall. Changes in the probabilities of occurrence of rainfall amounts within these climatic rainfall categories will influence the decisions that farmers and water managers will take. This research explores the changes produced by the North Atlantic oscillation (NAO) on the probability that local monthly rainfall takes in the southern Iberian Peninsula. The evolution of the NAO was divided into three phases: negative NAO, ,normal' NAO, and positive NAO, and local rainfall series were divided into three groups, corresponding to each NAO phase. The resulting empirical distribution functions were analysed and modelled by Gamma distributions. The results allow one to estimate the change in the probabilities of wet and dry months when a change in NAO phase is produced. The main result of this work is that changes in the probability of occurrence of climate categories of rainfall are more complex than only an increase of rainfall amount during the negative NAO phase and a decrease during the positive NAO phase. In fact, a certain asymmetry is detected in January, with more extremes linked to the negative NAO phase. Copyright © 2003 Royal Meteorological Society [source] The epidemiological aspects of irritable bowel syndrome in Southeastern Anatolia: a stratified randomised community-based studyINTERNATIONAL JOURNAL OF CLINICAL PRACTICE, Issue 3 2005erif Yilmaz Summary Even though studies on the epidemiology of the irritable bowel syndrome (IBS) are increasing day by day, epidemiological data are still unknown in many regions. Our objective was to determine the IBS prevalence, factors associated with this prevalence and probable risk groups in Southeastern Anatolia. The total population in the target region is approximately 6 million. A total of 3000 people (1521 females and 1479 males) randomly selected by stratified cluster sampling were interviewed face-to-face by using a questionnaire comprising demographic features and the Rome II criteria which also included probable risk factors and questions related with Bristol scale stool form. The statistical analysis was performed by using a package program called epi info 2000. IBS prevalence was 10.2% according to the Rome II criteria in our region. Six hundred and twenty-five of 3000 subjects had gastrointestinal symptoms in the last 3 months. IBS rate was higher in women (12.4%) than in men (8.0%), and married subjects had higher IBS rates (11.6%) than singles (6.7%). Those differences were statistically significant (p = 0.000 for both). It was most common in the 35,54-year age group. No difference was observed in terms of settlement (rural/urban), age group, education and occupation. History of abortion in women increased the IBS risk by 1.8 times (p = 0.000 Crude odds ratios = 1.8 (1.3,2.6) 95% confidence intervals). Of the IBS patients, 48.1% had characteristics of diarrhoea-predominance, 38.9% constipation-predominance while 13.0% had none. There was a significant relation between dominant stool form and Bristol scale stool form. IBS prevalence is 10.2% in the first community-based study carried out in this specific subject in Southeastern Anatolia. The dominance of middle age and females remained significant. [source] Measuring the social impacts of local authority events: a pilot study for a civic pride scaleINTERNATIONAL JOURNAL OF NONPROFIT & VOLUNTARY SECTOR MARKETING, Issue 3 2006Emma H. Wood The provision of events and festivals by local government has become an expected, if non-mandatory, service. In many regions these events are organised in order to provide mainly social, rather than economic, benefits to the community and, as a consequence, the providing organisation may have difficulty in demonstrating a return on the budget invested. This paper suggests the use of multi-item attitude scales to quantify the intangible effects of the festival or event programme on the local community. The findings of a pilot study of one such scale are presented showing that reliable and valid methods can be developed, that they can be relatively low cost and simple to apply and that the data generated can be of great value in enhancing the evaluation of local authority service provision. Copyright © 2006 John Wiley & Sons, Ltd. [source] Current status and prospects of agricultural drainage in China,IRRIGATION AND DRAINAGE, Issue S1 2007Wang Shaoli engorgement; salinisé alcalinisé; drainage agricole; environnement de l'eau Abstract Waterlogged and saline,alkali-affected soils are the main restrictions for agricultural production in many regions in China. Great efforts have been expended to conduct research on how to reclaim waterlogged and saline, alkali-affected soils for sustained agricultural productivity. Long-term practices have proved that agricultural drainage can be used to reduce the incidence of waterlogging and saline,alkali soil problems, as well as reclaim waterlogged and saline,alkali-affected soils, thus enhancing and sustaining agricultural productivity and national economic development. This paper describes the importance of agricultural drainage technology in China, reviews the current status of drainage technology, summarizing existing problems, and making some comparisons of drainage technologies from China and the USA. Future research needs in drainage technology for China are proposed. Copyright © 2007 John Wiley & Sons, Ltd. Les sols engorgés et salinisés ou alcalinisés sont les principaux freins à la production agricole dans de nombreuses régions de Chine. De grands efforts de recherche ont été déployés sur la façon de les récupérer pour améliorer la productivité agricole. Des pratiques de longue date ont montré que le drainage agricole peut être utilisé pour réduire l'incidence des problèmes posés par ces sols et pour les récupérer, favorisant de ce fait la productivité agricole et le développement économique national. Cet article décrit l'importance de la technologie du drainage agricole en Chine et passe en revue son état actuel, récapitulant les problèmes existants et comparant le drainage en Chine et aux Etats-Unis, pour terminer en proposant des efforts de recherche encore plus poussés en Chine. Copyright © 2007 John Wiley & Sons, Ltd. [source] Spontaneous succession in limestone quarries as an effective restoration tool for endangered arthropods and plantsJOURNAL OF APPLIED ECOLOGY, Issue 1 2010Robert Tropek Summary 1. The view of post-mining sites is rapidly changing among ecologists and conservationists, as sensitive restoration using spontaneous succession may turn such sites into biodiversity refuges in human-exploited regions. However, technical reclamation, consisting of covering the sites by topsoil, sowing fast-growing herb mixtures and planting trees, is still commonly adopted. Until now, no multi-taxa study has compared technically reclaimed sites and sites left with spontaneous succession. 2. We sampled communities of vascular plants and 10 arthropod groups in technically reclaimed and spontaneously restored plots in limestone quarries in the Bohemian Karst, Czech Republic. For comparison, we used paired t -tests and multivariate methods, emphasizing red-list status and habitat specialization of individual species. 3. We recorded 692 species of target taxa, with a high proportion of red-listed (10%) and xeric specialist (14%) species, corroborating the great conservation potential of the quarries. 4. Spontaneously restored post-mining sites did not differ in species richness from the technical reclaimed sites but they supported more rare species. The microhabitat cover of leaf litter, herbs and moss, were all directly influenced by the addition of topsoil during reclamation. 5.Synthesis and applications. Our results show that the high conservation potential of limestone quarries could be realized by allowing succession to progress spontaneously with minimal intervention. Given the threat to semi-natural sparsely vegetated habitats in many regions, active restoration measures at post-mining sites should be limited to maintenance of early successional stages, instead of acceleration of succession. [source] Comparative analysis of cost factors in sturgeon fingerling production in Iranian hatcheries (2000,2004)JOURNAL OF APPLIED ICHTHYOLOGY, Issue 5 2009H. Salehi Summary Production cost analysis in aquaculture is an essential exercise to assist farm managers. Economic assessment of a farm operation also provides the basis to formulate governmental aquaculture and enhancement policies in many regions. The present study employed questionnaires and interviewed managers while also using governmental statistics to gain insight into production cost variables in Iranian sturgeon hatcheries. Within a decade, production of sturgeon fingerlings for release and stock enhancement increased in Iran to more than 21 million fingerlings by 2004. Costs and contributions of various production factors were determined using data obtained from a questionnaire involving all hatcheries between 2000 and 2004. A team of experts completed the questionnaire data sets while conducting interviews at all sturgeon centres and other related departments. From 2000 to 2004 the contribution of A. persicus was 79% of the total number of sturgeon fingerlings produced followed by A. nudiventris with 7.5% and Huso huso with 6.6%. Among the various expenditures between 2000 and 2004, the costs for permanent and part-time employees contributed the greatest share of total costs, averaging 44%, with a noticeable declining trend from 51% in 2000 to 36% in 2004. Obtaining and incubating fertilized eggs averaged 22% of total costs, increasing during the same time period from 6 to 35%, respectively. On average, the 2000,2004 production cost for a single sturgeon fingerling was estimated at Rials 1667 (US$ 0.20), increasing from Rials 992 (US$ 0.12) to Rials 2623 (US$ 0.29) over these 4 years. Permanent staff at a hatchery was determined as being the principal cost, followed by costs for obtaining fertilized eggs (including broodstock handling). Over the 5-year study period the results indicated that costs for part-time labour declined yearly and, conversely, the costs of obtaining broodstocks as well as fertilizing and incubating eggs increased. Considering the background of hatchery production and stock enhancement of sturgeon species and the results of fishing data, it is possible to arrive at a first estimate of the potential contribution of Persian sturgeon farming to the total catch in Iranian waters; it is assumed that these increases were most likely through stock enhancement. [source] Phylogeography of the world's tallest angiosperm, Eucalyptus regnans: evidence for multiple isolated Quaternary refugiaJOURNAL OF BIOGEOGRAPHY, Issue 1 2010Paul G. Nevill Abstract Aim, There is a need for more Southern Hemisphere phylogeography studies, particularly in Australia, where, unlike much of Europe and North America, ice sheet cover was not extensive during the Last Glacial Maximum (LGM). This study examines the phylogeography of the south-east Australian montane tree species Eucalyptus regnans. The work aimed to identify any major evolutionary divergences or disjunctions across the species' range and to examine genetic signatures of past range contraction and expansion events. Location, South-eastern mainland Australia and the large island of Tasmania. Methods, We determined the chloroplast DNA haplotypes of 410 E. regnans individuals (41 locations) based on five chloroplast microsatellites. Genetic structure was examined using analysis of molecular variance (AMOVA), and a statistical parsimony tree was constructed showing the number of nucleotide differences between haplotypes. Geographic structure in population genetic diversity was examined with the calculation of diversity parameters for the mainland and Tasmania, and for 10 regions. Regional analysis was conducted to test hypotheses that some areas within the species' current distribution were refugia during the LGM and that other areas have been recolonized by E. regnans since the LGM. Results, Among the 410 E. regnans individuals analysed, 31 haplotypes were identified. The statistical parsimony tree shows that haplotypes divided into two distinct groups corresponding to mainland Australia and Tasmania. The distribution of haplotypes across the range of E. regnans shows strong geographic patterns, with many populations and even certain regions in which a particular haplotype is fixed. Many locations had unique haplotypes, particularly those in East Gippsland in south-eastern mainland Australia, north-eastern Tasmania and south-eastern Tasmania. Higher haplotype diversity was found in putative refugia, and lower haplotype diversity in areas likely to have been recolonized since the LGM. Main conclusions, The data are consistent with the long-term persistence of E. regnans in many regions and the recent recolonization of other regions, such as the Central Highlands of south-eastern mainland Australia. This suggests that, in spite of the narrow ecological tolerances of the species and the harsh environmental conditions during the LGM, E. regnans was able to persist locally or contracted to many near-coastal refugia, maintaining a diverse genetic structure. [source] Current Issues in the Economics of Groundwater Resource ManagementJOURNAL OF ECONOMIC SURVEYS, Issue 5 2004Phoebe Koundouri Abstract., The issue of groundwater management remains a practical concern in many regions throughout the world, while water managers continue to grapple with the question of how to manage this resource. In this article, we attempt to bring the most advanced and appropriate tools to bear on the issue of resource allocation involving groundwater. Our objective is to demonstrate the state of the art in the literature on ways to think about this complex resource and to deal with the important economic issues emanating from its complexity. We present the conceptual framework within which economists examine the elements interacting in the management of groundwater resources, indicate why the role of the market is limited with respect to the price of this very complex resource, and point to the mechanisms that can pull competitive groundwater price and quality-graded quantity of groundwater in line with their equilibrium levels. In particular, we critically review economic models of groundwater use, examine the potential for groundwater management, discuss the difficulties encountered in the estimation of the relevant control variables of such models, and identify the advantages and limitations of the instruments devised for the efficient use (allocation) of this resource. Finally, we argue that devised regulatory schemes usually ignore the information and knowledge needed for their implementation, and we suggest a core of conditions necessary for successful groundwater management reforms. [source] The Ozone Component of Global Change: Potential Effects on Agricultural and Horticultural Plant Yield, Product Quality and Interactions with Invasive SpeciesJOURNAL OF INTEGRATIVE PLANT BIOLOGY, Issue 4 2009Fitzgerald Booker The productivity, product quality and competitive ability of important agricultural and horticultural plants in many regions of the world may be adversely affected by current and anticipated concentrations of ground-level ozone (O3). Exposure to elevated O3 typically results in suppressed photosynthesis, accelerated senescence, decreased growth and lower yields. Various approaches used to evaluate O3 effects generally concur that current yield losses range from 5% to 15% among sensitive plants. There is, however, considerable genetic variability in plant responses to O3. To illustrate this, we show that ambient O3 concentrations in the eastern United States cause substantially different levels of damage to otherwise similar snap bean cultivars. Largely undesirable effects of O3 can also occur in seed and fruit chemistry as well as in forage nutritive value, with consequences for animal production. Ozone may alter herbicide efficacy and foster establishment of some invasive species. We conclude that current and projected levels of O3 in many regions worldwide are toxic to sensitive plants of agricultural and horticultural significance. Plant breeding that incorporates O3 sensitivity into selection strategies will be increasingly necessary to achieve sustainable production with changing atmospheric composition, while reductions in O3 precursor emissions will likely benefit world food production and reduce atmospheric concentrations of an important greenhouse gas. [source] Drought and salinity: A comparison of their effects on mineral nutrition of plantsJOURNAL OF PLANT NUTRITION AND SOIL SCIENCE, Issue 4 2005Yuncai Hu Abstract The increasing frequency of dry periods in many regions of the world and the problems associated with salinity in irrigated areas frequently result in the consecutive occurrence of drought and salinity on cultivated land. Currently, 50% of all irrigation schemes are affected by salinity. Nutrient disturbances under both drought and salinity reduce plant growth by affecting the availability, transport, and partitioning of nutrients. However, drought and salinity can differentially affect the mineral nutrition of plants. Salinity may cause nutrient deficiencies or imbalances, due to the competition of Na+ and Cl, with nutrients such as K+, Ca2+, and NO. Drought, on the other hand, can affect nutrient uptake and impair acropetal translocation of some nutrients. Despite contradictory reports on the effects of nutrient supply on plant growth under saline or drought conditions, it is generally accepted that an increased nutrient supply will not improve plant growth when the nutrient is already present in sufficient amounts in the soil and when the drought or salt stress is severe. A better understanding of the role of mineral nutrients in plant resistance to drought and salinity will contribute to an improved fertilizer management in arid and semi-arid areas and in regions suffering from temporary drought. This paper reviews the current state of knowledge on plant nutrition under drought and salinity conditions. Specific topics include: (1) the effects of drought and salt stress on nutrient availability, uptake, transport, and accumulation in plants, (2) the interactions between nutrient supply and drought- or salt-stress response, and (3) means to increase nutrient availability under drought and salinity by breeding and molecular approaches. Trockenstress und Salzstress , Vergleich der Auswirkungen auf die mineralische Ernährung von Pflanzen Eine Zunahme von Trockenperioden in vielen Ländern der Welt und assoziierte Probleme der Versalzung in bewässerten Gebieten führen häufig zu gleichzeitigem Auftreten von Trockenheit und Salinität. Gegenwärtig sind weltweit ungefähr 50 % aller Bewässerungsflächen durch Salinität beeinträchtigt. Nährstoffstörungen bei Trocken- und Salzstress beeinträchtigen die Verfügbarkeit, den Transport und die Verteilung von Nährelementen in der Pflanze und reduzieren somit das Pflanzenwachstum. Trocken- und Salzstress können sich jedoch unterschiedlich auf die Nährstoffversorgung der Pflanzen auswirken. Salinität kann aufgrund der Konkurrenz zwischen Na+ bzw. Cl, und Nährelementen wie K+, Ca2+ und NO Nährstoffmängel oder -ungleichgewichte in den Pflanzen verursachen. Trockenstress kann sowohl die Nährstoffaufnahme als auch den akropetalen Transport einiger Elemente beeinträchtigen. Trotz kontroverser Schlussfolgerungen in der Literatur hinsichtlich der Wechselbeziehungen von Nährstoffangebot und Trocken- bzw. Salzstress auf das Pflanzenwachstum ist allgemein akzeptiert, dass Nährstoffzufuhr das Pflanzenwachstum nicht verbessert, wenn ausreichend Nährstoffe im Boden verfügbar sind oder bei stark ausgeprägter Trockenheit oder Salinität. Ein besseres Verständnis der Rolle von Mineralstoffen in der Toleranz von Pflanzen gegenüber Trocken- oder Salzstress dürfte gerade in ariden und semi-ariden Gebieten sowie in Regionen, die unter periodischer Trockenheit leiden, zu verbesserten Düngestrategien beitragen. In der vorliegenden Arbeit wird der gegenwärtige Kenntnisstand der mineralischen Ernährung bei Trockenheit und Salinität diskutiert. Schwerpunkte der Betrachtungen sind (1) die Auswirkungen von Trockenheit und Salzstress auf die Verfügbarkeit, die Aufnahme, den Transport und die Anreicherung von Nährelementen in der Pflanze, (2) Wechselbeziehungen zwischen dem Nährstoffangebot und Trockenheit oder Salinität sowie (3) Maßnahmen zur Verbesserung der Nährstoffverfügbarkeit bei Trockenheit und Salzstress mittels züchterischer und molekularbiologischer Ansätze. [source] Securing water for people, crops, and ecosystems: New mindset and new prioritiesNATURAL RESOURCES FORUM, Issue 2 2003Sandra L Postel A fundamentally new approach to water and human development will be needed during this new century if we are to secure sufficient freshwater to meet the needs of some 9 billion people while at the same time protecting the critical ecosystem services upon which the human economy depends. Signs of unsustainable water use , including falling water tables, shrinking lakes, and the drying up of rivers and streams , are widespread and spreading. In many regions, greater modification and appropriation of freshwater systems for human purposes will yield greater costs than benefits and create the risk of irreversible losses of species and ecosystem services. A new mindset is needed to guide water use and management in this new century, one that views the human water economy as a subset of nature's water economy. Living within nature's limits will require that societies satisfy the basic needs of people and ecosystems before non-essential water demands are met. It will require on the order of a doubling of water productivity. And it will require stronger institutions to encourage equitable sharing of water to alleviate tensions within and between countries. [source] Characterization of inflammatory cells in oral paracoccidioidomycosisORAL DISEASES, Issue 4 2007E Kaminagakura Paracoccidioidomycosis (Pmycosis) is one of the most common deep mycoses in many regions of Latin America, particularly in Brazil. Microscopically, it shows granulomatous inflammatory reaction with giant cells, macrophages, lymphocytes, plasma cells, polymorphonuclear neutrophilic leukocytes, and eosinophils. The purpose of this study was to assess the distribution of inflammatory cells in oral Pmycosis. Fifteen cases of oral Pmycosis were studied by immunohistochemistry for the presence of macrophages, CD4+ and CD8+ lymphocytes, CD20+, CD15+, and S100+ cells. Macrophages were the main cells in well-organized granulomas and non-granulomatous areas. The CD4 phenotype was predominant in well-organized granulomas and a balance between CD4+ and CD8+ cells was observed in non-granulomatous areas. Dendritic, S100+ cells were found mainly in the epithelium, in subepithelial connective tissue, and at the periphery of organized granulomas. CD15+ cells were concentrated mainly in areas of intraepithelial microabscess and ulceration. Macrophages and T cells are the predominant cells in oral Pmycosis. Well-organized granulomas contain fewer yeast particles, indicating a more effective host immune response. Better understanding of the histopathological changes in oral Pmycosis might help determine treatment, severity and systemic involvement of the disease. [source] Antigen presentation and dendritic cell biology in malariaPARASITE IMMUNOLOGY, Issue 1-2 2006M. M. STEVENSON SUMMARY Dendritic cells (DCs) are important both in amplifying the innate immune response and in initiating adaptive immunity and shaping the type of T helper (Th) response. Although the role of DCs in immune responses to many intracellular pathogens has been delineated and research is underway to identify the mechanisms involved, relatively little is known concerning the role of DCs in immunity to malaria. In this review, we provide an overview and summary of previous and current studies aimed to investigate the role of DCs as antigen presenting cells (APCs). In addition, the role of DCs in inducing innate and adaptive immunity to blood-stage malaria is discussed and, where information is available, the mechanisms involved are presented. Data from studies in humans infected with Plasmodium falciparum, the major human parasite responsible for the high morbidity and mortality associated with malaria throughout many regions of the developing world, as well as data from experimental mouse models are presented. Overall, the data from these studies are conflicting. The possible reasons for these differences, including the use of different parasite species and parasite strains in the mouse studies, are discussed. Nevertheless, together the data have important implications for development of an effective malaria vaccine since the selection of appropriate Plasmodium antigens and/or adjuvants, targeting innate immune responses involving DCs, may provide optimal protection against malaria. It is hoped that this review promotes more investigation among malariologists and immunologists alike on DCs and malaria. [source] | |||||||||||||||||||||||||||||||||||||