Major Disruption (major + disruption)

Distribution by Scientific Domains


Selected Abstracts


Rain forest invasion of eucalypt-dominated woodland savanna, Iron Range, north-eastern Australia: II.

JOURNAL OF BIOGEOGRAPHY, Issue 8 2004
Rates of landscape change
Abstract Aim, To explore rates of rain forest expansion and associated ecological correlates in Eucalyptus -dominated woodland savanna vegetation in north-eastern Australia, over the period 1943,91. Location, Iron Range National Park and environs, north-east Queensland, Australia. This remote region supports probably the largest extent of lowland (< 300 m) rain forest extant in Australia. Rainfall (c. 1700 mm p.a.) occurs mostly between November and June, with some rain typically occurring even in the driest months July,October. Methods, Interpretation of change in lowland rain forest vegetation cover was undertaken for a 140 km2 area comprising complex vegetation, geology and physiography using available air photos (1943, 1970 and 1991). A GIS database was assembled comprising rain forest extent for the three time periods, geology, elevation, slope, aspect, proximity to streams and roads. Using standard GIS procedures, a sample of 6996 10 × 10 m cells (0.5% of study area) was selected randomly and attributed for vegetation structure (rain forest and non-rain forest), and landscape features. Associations of rain forest expansion with landscape features were examined with logistic regression using the subset of cells that had changed from other vegetation types to rain forest, and remained rain forest over the assessment period, and comparing them with cells that showed no change from their original, non-rain forest condition. Results, Rain forest in the air photo study area increased from 45 km2 in 1943 to 78.1 km2 by 1970, and to 82.6 km2 by 1991. Rainfall (and atmospheric CO2 concentration) was markedly lower in the first assessment period (1943,70). Modelled rates of rain forest invasion differed predominantly with respect to substrate type, occurring faster on substrates possessing better moisture retention properties, and across all elevation classes. Greatest expansion, at least in the first assessment period, occurred on the most inherently infertile substrates. Expansion was little constrained by slope, aspect and proximity to streams and roads. On schist substrates, probability of invasion remained high (> 60%) over distances up to 1500 m from mature rain forest margins; on less favourable substrates (diorite, granites), probability of expansion was negligible at sites more than 400 m from mature margins. Main conclusions, (i) Rain forest expansion was associated primarily with release from burning pressure from c. the 1920s, following major disruption of customary Aboriginal lifestyles including hunting and burning practices. (ii) Decadal-scale expansion of rain forest at Iron Range supports extensive observations from the palaeoecological literature concerning rapid rain forest invasion under conducive environmental conditions. (iii) The generality of these substrate-mediated observations requires further testing, especially given that landscape-scale rain forest invasion of sclerophyll-dominated communities is reported from other regions of north-eastern Australia. [source]


Idiopathic Hyperphosphatasia and TNFRSF11B Mutations: Relationships Between Phenotype and Genotype,

JOURNAL OF BONE AND MINERAL RESEARCH, Issue 12 2003
Belinda Chong
Abstract Homozygous mutations in TNFRSF11B, the gene encoding osteoprotegerin, were found in affected members from six of nine families with idiopathic hyperphosphatasia. The severity of the phenotype was related to the predicted effects of the mutations on osteoprotegerin function. Introduction: Idiopathic hyperphosphatasia (IH) is a rare high bone turnover congenital bone disease in which affected children are normal at birth but develop progressive long bone deformities, fractures, vertebral collapse, skull enlargement, and deafness. There is, however, considerable phenotypic variation from presentation in infancy with severe progressive deformity through to presentation in late childhood with minimal deformity. Two recent reports have linked idiopathic hyperphosphatasia with deletion of, or mutation in, the TNFRSF11B gene that encodes osteoprotegerin (OPG), an important paracrine modulator of RANKL-mediated bone resorption. Materials and Methods: We studied subjects with a clinical diagnosis of IH and unaffected family members from nine unrelated families. Clinical, biochemical, and radiographic data were collected, and genomic DNA examined for mutations in TNFRSF11B. The relationship between the mutations, their predicted effects on OPG function, and the phenotype were then examined. Results: Of the nine families studied, affected subjects from six were homozygous for novel mutations in TNFRSF11B. Their parents were heterozygous, consistent with autosomal recessive inheritance. Four of the six mutations occurred in the cysteine-rich ligand-binding domain and are predicted to disrupt binding of OPG to RANKL. Missense mutations in the cysteine residues, predicted to cause major disruption to the ligand-binding region, were associated with a severe phenotype (deformity developing before 18 months age and severe disability), as was a large deletion mutation. Non-cysteine missense mutations in the ligand-binding domain were associated with an intermediate phenotype (deformity recognized around the age of 5 years and an increased rate of long bone fracture). An insertion/deletion mutation at the C-terminal end of the protein was associated with the mildest phenotype. Conclusion: Mutations in TNFRSF11B account for the majority of, but not all, cases of IH, and there are distinct genotype-phenotype relationships. [source]


Effect of conditioning electrical stimuli on temporalis electromyographic activity during sleep

JOURNAL OF ORAL REHABILITATION, Issue 3 2008
F. JADIDI
Summary, Inhibitory reflexes during voluntary contractions are well described; however, few studies have attempted to use such reflex-mechanisms to modulate electromyographic (EMG) activity in jaw-closing muscles during sleep. The aim was to apply a new intelligent biofeedback device (Grindcare®) using electrical pulses to inhibit EMG activity in the temporalis muscle during sleep. Fourteen volunteers participated who were aware of jaw-clenching activity as indicated by complaints from sleep partner, soreness or pain in the jaw-muscle upon awakening and tooth wear facets. The EMG activity was recorded from the temporalis muscle, online analysed and the frequency content determined using a signal recognition algorithm. Based on specific individual parameters for pattern recognition, an electrical square-wave pulse train, which was adjusted to a clear, but non-painful intensity (range 1,7 mA) was applied through the EMG electrodes, if jaw-clenching activity was detected. All volunteers had baseline EMG recordings for five to seven consecutive nights, followed by 3-weeks EMG recordings with the feedback turned on, 2 weeks without the feedback and finally 3 weeks with the biofeedback on. There were no session effects on the average duration of sleep hours (P = 0·626). The number of EMG episodes/hour sleep was significantly reduced during the two sessions with biofeedback (54 ± 14%; 55 ± 17%, P < 0·001) compared with baseline EMG activity and the session without biofeedback. The present study suggests that biofeedback with electrical pulses does not cause major disruption in sleep and is associated with pronounced reduction in temporalis EMG activity during sleep. [source]


The impact of prolonged fasting during aestivation on the structure of the small intestine in the green-striped burrowing frog, Cyclorana alboguttata

ACTA ZOOLOGICA, Issue 1 2005
Rebecca L. Cramp
Abstract The effects of short-term fasting and prolonged fasting during aestivation on the morphology of the proximal small intestine and associated organs were investigated in the green-striped burrowing frog, Cyclorana alboguttata (Anura: Hylidae). Animals were fasted for 1 week while active or for 3,9 months during aestivation. Short-duration fasting (1 week) had little effect on the morphology of the small intestine, whilst prolonged fasting during aestivation induced marked enteropathy including reductions in intestinal mass, length and diameter, longitudinal fold height and tunica muscularis thickness. Enterocyte morphology was also affected markedly by prolonged fasting: enterocyte cross-sectional area and microvillous height were reduced during aestivation, intercellular spaces were visibly reduced and the prevalence of lymphocytes amongst enterocytes was increased. Mitochondria and nuclei were also affected by 9 months of aestivation with major disruptions to mitochondrial cristae and increased clumping of nuclear material and increased infolding of the nuclear envelope. The present study demonstrates that the intestine of an aestivating frog responds to prolonged food deprivation during aestivation by reducing in size, presumably to reduce the energy expenditure of the organ. [source]


Calculation of Elapsed Decimal Time for Tracing Studies

GROUND WATER, Issue 1 2008
Malcolm S. Field
Calculation of time of travel from tracing studies in hydrologic systems is critical to establishing pollutant arrival times from points of inflow to points outflow, calculating subsurface flow velocities, and determining other important transport parameters such as longitudinal dispersion. In addition, breakthrough curve modeling demands accurate time of travel calculations if model results are to have any realistic meaning. However, accurate time of travel calculations are very difficult for long tracer tests in which sampling schedules are not consistent, or when there are major disruptions such as may occur when adverse weather conditions cause automatic sampling equipment to fail. Long and inconsistent sampling times may be accurately converted to decimal times of travel by converting the conventionally recorded Coordinated Universal Time for sampling date and time event to a baseline time standard. By converting to a baseline time standard, all recorded dates and times are linked to the established baseline standard so that each succeeding sampling date and time are correctly determined relative to the previous sampling date and time and to the injection date and time. [source]