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Male Sexual Function (male + sexual_function)

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Medical Sciences	100%

Selected Abstracts

Effect of Hyperprolactinemia in Male Patients Consulting for Sexual Dysfunction

THE JOURNAL OF SEXUAL MEDICINE, Issue 5 2007
Giovanni Corona MD
ABSTRACT Introduction., The physiological role of prolactin (PRL) in male sexual function has not been completely clarified. Aim., The aim of this study is the assessment of clinical features and of conditions associated with hyperprolactinemia in male patients consulting for sexual dysfunction. Methods., A consecutive series of 2,146 (mean age 52.2 ± 12.8 years) male patients with sexual dysfunction was studied. Main Outcome Measures., Several hormonal and biochemical parameters were studied along with validated structured interviews (ANDROTEST and the Structured Interview on Erectile Dysfunction [SIEDY]). Mild hyperprolactinemia (MHPRL; PRL levels of 420,735 mU/L or 20,35 ng/mL) and severe hyperprolactinemia (SHPRL, PRL levels >735 mU/L, 35 ng/mL) were considered. Results., MHPRL and SHPRL were found in 69 (3.3%) and in 32 (1.5%) patients, respectively. Mean age and the prevalence of gynecomastia were similar in the two groups and in subjects with normal prolactin values. MHPRL was not confirmed in almost one-half of the patients after repetitive venous sampling. Hyperprolactinemia was associated with the current use of antidepressants, antipsychotic drugs, and benzamides. SHPRL was also associated with hypoactive sexual desire (HSD), elevated thyrotropin (TSH), and hypogonadism. The association between HSD and SHPRL was confirmed after adjustment for testosterone and TSH levels, and use of psychotropic drugs (hazard ratio [HR] = 8.60[3.85,19.23]; P < 0.0001). In a 6-month follow-up of patients with SHPRL, testosterone levels and sexual desire were significantly improved by the treatment. Conclusions., Our data indicate that SHPRL, but not MHPRL, is a relevant determinant of HSD. Gynecomastia does not help in recognizing hyperprolactinemic subjects, while the use of psychotropic medications and HSD are possible markers of disease. In the case of MHPRL, repetitive venous sampling is strongly encouraged. Corona G, Mannucci E, Fisher AD, Lotti F, Ricca V, Balercia G, Petrone L, Forti G, and Maggi M. Effect of hyperprolactinemia in male patients consulting for sexual dysfunction. J Sex Med 2007;4:1485,1493. [source]

ORIGINAL RESEARCH,ERECTILE DYSFUNCTION: Journey into the Realm of Requests for Help Presented to Sexual Medicine Specialists: Introducing Male Sexual Distress

THE JOURNAL OF SEXUAL MEDICINE, Issue 3 2007
Edoardo S. Pescatori MD
ABSTRACT Introduction., The recent availability of noninvasive pharmacological remedies for male sexual function triggered an exponential increase in the number of men requesting help in the sexuality area. Aim., The Italian Society of Andrology explored requests for help, not included in formerly established clinical categories of sexual medicine. Methods., A central board of 67 andrologists identified new areas of requests for help, instrumental for a web-based questionnaire, forwarded to 912 members of the Italian Society of Andrology. Results were submitted to an independent consensus development panel. Main Outcome Measures., A questionnaire response rate of 30.8% was considered acceptable according to standard response rates of medical specialist samples. Results., The Central Board interaction identified two new domains of requests for help: sexual distress and unconventional requests for pro-erectile medications. Web-based questionnaire results suggested that such domains account for 29% and 9% respectively of all requests for help already presented by male patients at sexual medicine clinics. The Independent Consensus Development Panel issued a final consensus document; herewith, the statement defining male sexual distress: A non-transitory condition and/or feeling of inadequacy such as to impair "sexual health" (WHO working definition). Inadequacy can originate both from physiological modifications of male sexual functions, and from diseases, dysfunctions, dysfunctional symptoms and dysmorphisms, both of andrological and non-andrological origin, which do not relate to "erectile dysfunction" (NIH Consensus Development Panel definition), but that might also induce erectile dysfunction. Sexual Distress can lead to a request for help which needs to be acknowledged. Conclusion., The Italian Society of Andrology identified two new areas of requests for help concerning male sexual issues: sexual distress and unconventional requests for pro-erectile medications. These domains, which do not represent new diseases, nonetheless induce the sufferers to seek help and, accordingly, need to be acknowledged. Pescatori ES, Giammusso B, Piubello G, Gentile V, and Pirozzi Farina F. Journey into the realm of requests for help presented to sexual medicine specialists: Introducing male sexual distress. J Sex Med 2007;4:762,770. [source]

The Male Sexual Quotient: A Brief, Self-Administered Questionnaire to Assess Male Sexual Satisfaction

THE JOURNAL OF SEXUAL MEDICINE, Issue 2 2007
Carmita H.N. Abdo MD
ABSTRACT Introduction., Sexual satisfaction is an important aspect of overall life satisfaction. The Male Sexual Quotient (MSQ) was designed to provide a versatile, user-friendly instrument to measure various aspects of male sexual function and satisfaction. Aim., Assess responses to the MSQ in men with sexual dysfunction (SD). Methods., Items for inclusion in the MSQ were developed through interviewing 612 randomly recruited men in São Paulo, Brazil, about factors considered to influence sexual quality of life. Validation of the MSQ was conducted in two phases in men with and without SD. Main Outcome Measure., The correlation between patients' total MSQ score and scores on the Sexual Health Inventory for Men (SHIM). Results., The resulting MSQ questionnaire contains 10 items that address sexual function and satisfaction and is scored on a 100-point scale, with higher scores indicating greater sexual function and satisfaction with such function. Patients' scores on the MSQ were positively correlated with scores on the SHIM (r = 0.86; P < 0.0001). Scores on MSQ item 8, which assesses ejaculatory control, indicated that 46% of patients may have premature ejaculation (PE). The mean time for patients to complete the MSQ was 11 minutes. Conclusions., The MSQ is a brief, comprehensive, and easily self-administered tool designed to help men identify aspects of their sexual experience that could be improved through partner dialogue, physician consultation, and appropriate treatment. MSQ scores correlated well with SHIM scores, and scores were inversely related to the severity of erectile dysfunction or PE and other male SDs. These preliminary findings suggest that the MSQ possesses good convergent validity. Nearly half of men reported problems with ejaculatory control, indicating an association between PE and other SD. Further validation of the MSQ in a double-blind trial is needed. The MSQ may aid in decision making for the treatment of SD. Abdo CHN. The Male Sexual Quotient: A brief, self-administered questionnaire to assess male sexual satisfaction. J Sex Med 2007;4:382,389. [source]

Assessment of male sexual function by the Brief Sexual Function Inventory

BJU INTERNATIONAL, Issue 2 2006
ARNSTEIN MYKLETUN
OBJECTIVE To present normative data from Norway using the Brief Male Sexual Function Inventory (BSFI, the first patient self-administered questionnaire to assess male sexuality, and used in the USA) in men aged 20,79 years, examine the psychometric properties of the BSFI, explore the impact of sexual function and other variables on overall sexual satisfaction, and compare American and Norwegian normative data. SUBJECTS AND METHODS From public official address lists 3500 men aged 20,79 years were invited to take part in an anonymous questionnaire study, including the BSFI. Altogether 1185 (34%) responded, and the response rates varied with age. RESULTS There was increasingly reduced sexual function concerning drive, erection, ejaculation, and problem assessment with age, and most of the age-effect started at >50 years old. Overall sexual satisfaction followed the same trend, but with a weaker association with age. Analyses of factor structure and internal consistency of the BSFI supported a one-factor solution with good internal consistency. Drive, erection, ejaculation, and problem assessment explained 28% of the variance in overall sexual satisfaction. Being younger and having a sexual partner were also associated with high scores of overall sexual satisfaction. American and Norwegian normative data in the BSFI dimensions were markedly similar. CONCLUSION The BSFI is a short and discrete screening tool for sexual function, and for most clinical and research purposes we recommend using the BSFI as a one-dimensional scale. [source]

ORIGINAL RESEARCH,ERECTILE DYSFUNCTION: Journey into the Realm of Requests for Help Presented to Sexual Medicine Specialists: Introducing Male Sexual Distress