Longer Timescales (longer + timescale)

Distribution by Scientific Domains


Selected Abstracts


Biophysical studies of the development of amyloid fibrils from a peptide fragment of cold shock protein B

FEBS JOURNAL, Issue 9 2000
Deborah K. Wilkins
The peptide CspB-1, which represents residues 1,22 of the cold shock protein CspB from Bacillus subtilis, has been shown to form amyloid fibrils when solutions containing this peptide in aqueous (50%) acetonitrile are diluted in water [M. Großet al. (1999) Protein Science8, 1350,1357] We established conditions in which reproducible kinetic steps associated with the formation of these fibrils can be observed. Studies combining these conditions with a range of biophysical methods reveal that a variety of distinct events occurs during the process that results in amyloid fibrils. A CD spectrum indicative of ,,structure is observed within 1 min of the solvent shift, and its intensity increases on a longer timescale in at least two kinetic phases. The characteristic wavelength shift of the amyloid-binding dye Congo Red is established within 30 min of the initiation of the aggregation process and corresponds to one of the phases observed by CD and to changes in the Fourier transform-infrared spectrum indicative of ,,structure. Short fibrillar structures begin to be visible under the electron microscope after these events, and longer, well-defined amyloid fibrils are established on a timescale of hours. NMR spectroscopy shows that there are no significant changes in the concentration of monomeric species in solution during the events leading to fibril formation, but that soluble aggregates too large to be visible in NMR spectra are present throughout the process. A model for amyloid formation by this peptide is presented which is consistent with these kinetic data and with published work on a variety of disease-related systems. These findings support the concept that the ability to form amyloid fibrils is a generic property of polypeptide chains, and that the mechanism of their formation is similar for different peptides and proteins. [source]


Assembly, tuning, and transfer of action systems in infants and robots

INFANT AND CHILD DEVELOPMENT, Issue 1 2008
Luc Berthouze
Abstract This paper seeks to foster a discussion on whether experiments with robots can inform theory in infant motor development and specifically (1) how the interactions among the parts of a system, including the nervous and musculoskeletal systems and the forces acting on the body, induce organizational changes in the whole, and (2) how exploratory behaviour and selective informational signals at the timescale of skill learning may allow behaviour to become stabilized at the longer timescale of development. The paper describes how three generative principles, inspired from developmental biology and shown to underlie the dynamics of infants learning to bounce in a Jolly Jumper, were broken into a set of mechanisms suitable for controlling a robotic system and resulted in a similar developmental profile. A comparison of infant and robot data leads to a set of criteria for improving the usefulness of robotic studies. Copyright © 2008 John Wiley & Sons, Ltd. [source]


The apparent temperature response of leaf respiration depends on the timescale of measurements: a study of two cold climate species

PLANT BIOLOGY, Issue 2 2008
D. Bruhn
Abstract Productivity and climate models often use a constant Q10 for plant respiration, assuming tight control of respiration by temperature. We studied the temperature response of leaf respiration of two cold climate species (the Australian tree Eucalyptus pauciflora and the subantarctic megaherb Pringlea antiscorbutica, both measured in a field setting) on a short timescale (minutes) during different times within a diel course, and on a longer timescale, using diel variations in ambient temperature. There were great variations in Q10 depending on measuring day, measuring time and measuring method. When Q10 was calculated from short-term (15 min) manipulations of leaf temperature, the resulting values were usually markedly smaller than when Q10 was calculated from measurements at ambient leaf temperatures spread over a day. While for E. pauciflora, Q10 estimates decreased with rising temperature (corroborating the concept of a temperature-dependent Q10), the opposite was the case for P. antiscorbutica. Clearly, factors other than temperature co-regulate both leaf respiration rates and temperature sensitivity and contribute to diel and seasonal variation of respiration. [source]


Aeolian fetch distance and secondary airflow effects: the influence of micro-scale variables on meso-scale foredune development

EARTH SURFACE PROCESSES AND LANDFORMS, Issue 7 2008
Kevin Lynch
Abstract Unsuccessful attempts to use process-scale models to predict long-term aeolian sediment transport patterns have long been a feature of aeolian research. It has been proposed that one approach to overcome these problems is to identify micro-scale variables that are important at longer timescales. This paper assesses the contribution of two system variables (secondary airflow patterns and fetch distance) to medium-term (months to years) dune development. The micro-scale importance of these variables had been established during previous work at the site (Magilligan Strand, Northern Ireland). Three methods were employed. First, sand drift potentials were calculated using 2 years of regional wind data and a sediment transport model. Second, wind data and large trench traps (2 m length × 1 m width × 1·5 m depth) were used to assess the actual sediment transport patterns over a 2-month period. Third, a remote-sensing technique for the identification of fetch distance, a saltation impact sensor (Safire) and wind data were utilized to gauge, qualitatively, sediment transport patterns over a 1-month period. Secondary airflow effects were found to play a major role in the sediment flux patterns at these timescales, with measured and predicted rates matching closely during the trench trap study. The results suggest that fetch distance is an unimportant variable at this site. Copyright © 2007 John Wiley & Sons, Ltd. [source]


Did the Indo-Asian summer monsoon decrease during the Holocene following insolation?,

JOURNAL OF QUATERNARY SCIENCE, Issue 7 2010
Manish Tiwari
Abstract A few studies from the western Arabian Sea indicate that the Indian summer (or southwest) monsoon (ISM), after attaining its maximum intensity at ca. 9,ka, declined during the Holocene, as did insolation. In contrast, earlier and later observations from both the eastern and the western Arabian Sea do not support this inference. Analysis of multiple proxies of productivity in a new sediment core from the western Arabian Sea fails to confirm the earlier, single-proxy (e.g. abundance of Globigerina bulloides) based, inference of the Holocene weakening of ISM, following insolation. The reason for the observed decreasing trend in foraminiferal abundance , the basis for the earlier inference , could be the favouring of silicate rather than carbonate productivity by the increased ISM wind strength. Although ISM exhibits several multi-millennial scale fluctuations, there is no evidence from several multi-proxy data to conclude that it declined during the Holocene; this is consistent with the phase lag analysis of longer time series of monsoon proxies. Thus, on sub-Milankovitch timescales, ISM did not follow insolation, highlighting the importance of internal feedbacks. A comparison with East Asian summer monsoon (EASM) records suggests that both ISM and EASM varied in unison, implying common forcing factors on such longer timescales. Copyright © 2010 John Wiley & Sons, Ltd. [source]


A multicentury perspective on the summer North Atlantic Oscillation (SNAO) and drought in the eastern Atlantic Region,

JOURNAL OF QUATERNARY SCIENCE, Issue 5 2009
Hans W. Linderholm
Abstract The summer North Atlantic Oscillation (SNAO) is strongly associated with July,August climate variability over Europe, especially in northern regions. This association includes drought, where a positive SNAO corresponds to dry conditions over much of northern Europe and wet conditions in southern Europe, but the SNAO/climate association is weaker and less homogeneous in the south. Here we use a dendroclimatological reconstruction of the SNAO for the last 550 a to investigate the SNAO/drought relationship in the past. An association between the SNAO and a regional summer drought index from Sweden suggests that the northern European drought relationship holds back to 1700. In the last 550 a, the relationship between SNAO and drought in the Mediterranean region as a whole is weak, but over the Eastern Mediterranean the relationship is clearer and statistically significant (P,<,0.05 level). The Mediterranean relationship is clearest at century scales. An association between the SNAO and Sahel rainfall can clearly be seen on interannual as well as longer timescales in the 20th century. Past droughts in the Sahel, as inferred from historical data, correspond quite well with positive phases of the SNAO on multidecadal timescales back to 1500, the phase expected from instrumental data. The physical reasons for the relationship between Sahel rainfall and the SNAO are, however, not yet understood. This research is a first step towards understanding how the atmospheric circulation over the North Atlantic region affects drought, necessary for forecast future droughts. Copyright © 2009 John Wiley & Sons, Ltd. and © Crown Copyright 2009. [source]


Extension of ideal free resource use to breeding populations and metapopulations

OIKOS, Issue 1 2000
C. Patrick Doncaster
The concept of an ideal and free use of limiting resources is commonly invoked in behavioural ecology as a null model for predicting the distribution of foraging consumers across heterogeneous habitat. In its original conception, however, its predictions were applied to the longer timescales of habitat selection by breeding birds. Here I present a general model of ideal free resource use, which encompasses classical deterministic models for the dynamics in continuous time of feeding aggregations, breeding populations and metapopulations. I illustrate its key predictions using the consumer functional response given by Holling's disc equation. The predictions are all consistent with classical population dynamics, but at least two of them are not usually recognised as pertaining across all scales. At the fine scale of feeding aggregations, the steady state of an equal intake for all ideal free consumers may be intrinsically unstable, if patches are efficiently exploited by individuals with a non-negligible handling time of resources. At coarser scales, classical models of population and metapopulation dynamics assume exploitation of a homogeneous environment, yet they can yield testable predictions for heterogeneous environments too under the assumption of ideal free resource use. [source]