Home About us Contact
|
Home About us Contact | ||
|
|
||
Long History (long + history)
Selected AbstractsReflections on Lack of a Patent System throughout China's Long HistoryTHE JOURNAL OF WORLD INTELLECTUAL PROPERTY, Issue 2 2009Deming Liu The accepted wisdom is that the patent system originated in Europe and that China did not have such an indigenous system throughout its history. The reasons for the lack of such a system are not often explored among legal scholars although, for decades, historians have debated on a related matter of why the Industrial Revolution did not start in China after its centuries' lead in science and technology. It appears that legal scholars generally accept that Confucian philosophy precluded an intellectual property system in China including a patent system. The article aims to dispute this belief by showing that socioeconomic and geographical factors underscored the main reasons for the lack of a patent system in ancient China. [source] Reconstructing ripeness II: Models and methods for fostering constructive stakeholder engagement across protracted dividesCONFLICT RESOLUTION QUARTERLY, Issue 1 2008Peter T. Coleman A priority objective for diplomats, mediators, negotiators, and other individuals working to rectify seemingly intractable conflicts is to help foster stakeholder "ripeness," or a willingness and commitment to engage constructively in the conflict. This is often extremely difficult to achieve due to long histories between the parties of animosity, suspicion, hostility, and fear. Ripeness theory has been a useful starting point for understanding such motives, but has limited explanatory power under conditions of intractable conflict. The second in a two-part series, this article outlines the implications for practice resulting from an analysis of interviews with expert scholar-practitioners working in the field with intractable conflicts. [source] Antisense applications for biological controlJOURNAL OF CELLULAR BIOCHEMISTRY, Issue 1 2006Wei-Hua Pan Abstract Although Nature's antisense approaches are clearly impressive, this Perspectives article focuses on the experimental uses of antisense reagents (ASRs) for control of biological processes. ASRs comprise antisense oligonucleotides (ASOs), and their catalytically active counterparts ribozymes and DNAzymes, as well as small interfering RNAs (siRNAs). ASOs and ribozymes/DNAzymes target RNA molecules on the basis of Watson-Crick base pairing in sequence-specific manner. ASOs generally result in destruction of the target RNA by RNase-H mediated mechanisms, although they may also sterically block translation, also resulting in loss of protein production. Ribozymes and DNAzymes cleave target RNAs after base pairing via their antisense flanking arms. siRNAs, which contain both sense and antisense regions from a target RNA, can mediate target RNA destruction via RNAi and the RISC, although they can also function at the transcriptional level. A considerable number of ASRs (mostly ASOs) have progressed into clinical trials, although most have relatively long histories in Phase I/II settings. Clinical trial results are surprisingly difficult to find, although few ASRs appear to have yet established efficacy in Phase III levels. Evolution of ASRs has included: (a) Modifications to ASOs to render them nuclease resistant, with analogous modifications to siRNAs being developed; and (b) Development of strategies to select optimal sites for targeting. Perhaps the biggest barrier to effective therapies with ASRs is the "Delivery Problem." Various liposomal vehicles have been used for systemic delivery with some success, and recent modifications appear to enhance systemic delivery, at least to liver. Various nanoparticle formulations are now being developed which may also enhance delivery. Going forward, topical applications of ASRs would seem to have the best chances for success. In summary, modifications to ASRs to enhance stability, improve targeting, and incremental improvements in delivery vehicles continue to make ASRs attractive as molecular therapeutics, but their advance toward the bedside has been agonizingly slow. J. Cell. Biochem. 98: 14,35, 2006. © 2006 Wiley-Liss, Inc. [source] Front and Back Covers, Volume 21, Number 5.ANTHROPOLOGY TODAY, Issue 5 2005October 200 Front and back cover caption, volume 21 issue 5 Front cover Children in the favela (squatter community) of 'Caxambu', in the northern zone of Rio de Janeiro, Brazil. Although favelas are often depicted as dangerous and as the housing option of last resort, they are also characterized by dense and multi-stranded social ties between residents, long histories of occupation and settlement, and multi-generational families. Caxambu (a pseudonym) was originally settled at the beginning of the 20th century, and residents often describe the neighbourhood as a 'big family'. As the photo makes clear, the alleys, street corners and other public spaces in the favela often serve as giant playgrounds for local children. Back cover THE HUMAN BODY The photo on the back cover shows one of the exhibits from Gunther von Hagens' anatomical exhibition Body Worlds, discussed by Uli Linke in this issue. The exhibits in this show are fashioned from human corpses. The male figure shown here, the body of a man holding and gazing at his own skin, attempts to convey something about the human skin. The anatomical museum markets corpses, artfully transformed to appeal to the viewer. Body Worlds has toured internationally, and attracted millions of visitors. Dead bodies are transformed into sensually appealing 'works of art', playing to fantasies of the alluring body common to the dream worlds promoted by multinational media and entertainment industries. In the exhibition anatomy and pedagogy, economy and medical science, pathology and human rights are closely intertwined. But where do the bodies come from? The corpses, contrary to the exhibitor's claims, are not supplied by German donors - they are procured from Eastern Europe, Russia, Kyrgyzstan and China, from places where human rights and bioethical standards are not enforced. Von Hagens insists that bodies displayed are from donors, and his exhibition website (www.bodyworlds.com) welcomes donations to its body donation programme. In his body factory in Dalian, China, thousands of corpses, including the remains of executed prisoners, are flayed and prepared for later use. This trade in bodies, a multi-million-dollar enterprise, is highly problematic. For the trumpeted 'art of anatomy', with its beautified corpses and eroticized installations, also has a violent dimension, with human victims whose bodies are bought and sold for profit. In November 2002, Gunther von Hagens risked prosecution by holding the first public dissection of a (donated) body in the UK since the 1830s, in London's Atlantis Gallery. The issues surrounding procurement, preparation, dissection and display of human remains are central to anthropology, and in this article Uli Linke discusses in particular the various ways in which this exhbition was interpreted in Germany. [source] An independent person in action under the Children Act 1989 complaints procedureCHILDREN & SOCIETY, Issue 4 2001Gillian Bridge Under Section 26 (4) of the Children Act 1989, local authorities are obliged to appoint independent people to participate in investigations at stage two of the complaints procedure. The nature of their role and tasks were ill defined by the Department of Health Guidance (1991), and hitherto there has been little research in this area. Using the author's experiences, this discussion paper examines some of the dilemmas of undertaking this role, and raises questions about how independent people are meeting legal requirements. From the material discussed here, it appears that the system of including independent people in complaints' investigations is not meeting the intended objectives of ensuring that complaints by young people themselves benefit from impartial scrutiny. Instead, independent people are mainly engaged with investigating officers in unravelling complex situations, many with long histories of serious breakdowns in communication between parents, carers and local authority children's services. In the light of these findings, the Department of Health's recent consultation paper, Listening to People is welcome, although rather disappointing in restricting its attention largely to procedural issues. In this paper the author promotes greater attention to the growing expertise of independent people currently investigating complaints. Additionally it is recommended that a more accessible means for young people to complain should be devised. Copyright © 2001 John Wiley & Sons, Ltd. [source] GETTING BY THE OCCUPATION: How Violence Became Normal during the Second Palestinian IntifadaCULTURAL ANTHROPOLOGY, Issue 3 2008LORI ALLEN ABSTRACT The second Palestinian intifada against Israeli occupation, which began in September 2000, saw Palestinian areas repeatedly invaded and shelled by Israeli forces. A long history of war and targeted cities is told along the thoroughfares of Palestinian towns; memories of past battles and defeats inscribed in street signs recall massacres in places like Tel Al-Za'atar and Deir Yasin. But recent events were more important than any official marker and formed the most relevant base by which Palestinians organized their lives. Commemorative cultural production and basic acts of physically getting around that became central to the spatial and social practices by which reorientation and adaptation to violence occurred in the occupied Palestinian territories. This article analyzes the spaciotemporal, embodied, and symbolic aspects of the experience of violence, and the political significance of cultural practices whereby violence is routinized. Such an approach provides a lens onto the power of violence in Israel's colonial project in the occupied territories that neither necessitates an assumption that violence is all determining of Palestinian experience, nor a championing of every act of Palestinian survival as heroic resistance. Memorialization that occurs in storytelling, in visual culture, in the naming of places and moving through spaces is one way in which this happens. The concept of "getting by" captures the many spatial and commemorative forms by which Palestinians manage everyday survival. The kind of agency that is entailed in practices whereby people manage, get by, adapt, and the social significance of getting used to it may be somewhat nebulous and unobtrusive as it develops in the shadow of spectacular battles and bloodshed. I demonstrate that this routinization of violence in and of itself, the fact of getting by, just existing in an everyday way, is socially and politically significant in Palestine. [source] Instrument to assess depersonalization-derealization in panic disorderDEPRESSION AND ANXIETY, Issue 4 2002Brian J. Cox Ph.D. Abstract There is a long history of scholarly interest on depersonalization-derealization (DD) and its role in clinical anxiety, but there is a paucity of appropriate assessment instruments available. Our objective was to develop and evaluate a self-report measure of DD for use with clinically anxious patients. Panic disorder patients (n=169) were surveyed about DD experiences and provided data on a new item pool for psychometric development. DD episodes were common and a 28-item Depersonalization-Derealization Inventory was found to possess good reliability and validity. DD appears to be prevalent and clinically relevant in panic disorder. Continued study of DD is warranted and may be facilitated by the availability of a suitable instrument with promising psychometric properties. A 12-item version of the instrument may be appropriate as a brief screen. © 2002 Wiley-Liss, Inc. [source] Toward a neuro-developmental account of the development of declarative memoryDEVELOPMENTAL PSYCHOBIOLOGY, Issue 1 2008Patricia J. Bauer Abstract The study of the biological bases of memory has a long history. Based on research with patients with specific lesions and disease, animal models, and neuroimaging studies, the neural substrate that supports declarative memory in adults has been relatively well articulated. By contrast, studies of the neural bases of memory in development is in its infancy. Yet joint consideration of the processes involved in building a memory trace, and of the time course of development of the neural structures involved, has contributed to the generation of specific predictions regarding the sources of age-related change. Specifically, there are suggestions that in infancy and very early childhood, encoding and consolidation processes account for substantial age-related variance in long-term declarative memory. With development, the locus of age-related variability in the vulnerability of memory traces shifts to the later-stage processes of memory storage and retrieval. These insights are afforded by consideration of multiple levels of analysis, from the biological to the behavioral. © 2007 Wiley Periodicals, Inc. Dev Psychobiol 50: 19,31, 2008. [source] The potential of cinnamon to reduce blood glucose levels in patients with type 2 diabetes and insulin resistanceDIABETES OBESITY & METABOLISM, Issue 12 2009S. Kirkham Aim: Cinnamon has a long history as an antidiabetic spice, but trials involving cinnamon supplementation have produced contrasting results. The aim of this review was to examine the results of randomized controlled clinical trials of cinnamon and evaluate the therapeutic potential amongst patients with diabetes and insulin-resistant patients, particularly the ability to reduce blood glucose levels and inhibit protein glycation. Methods: A systematic electronic literature search using the medical subject headings ,cinnamon' and ,blood glucose' was carried out to include randomized, placebo-controlled in vivo clinical trials using Cinnamomum verum or Cinnamomum cassia conducted between January 2003 and July 2008. Results: Five type 2 diabetic and three non-diabetic studies (total N = 311) were eligible. Two of the diabetic studies illustrated significant fasting blood glucose (FBG) reductions of 18,29% and 10.3% (p < 0.05), supported by one non-diabetic trial reporting an 8.4% FBG reduction (p < 0.01) vs. placebo, and another illustrating significant reductions in glucose response using oral glucose tolerance tests (p < 0.05). Three diabetic studies reported no significant results. Conclusions: Whilst definitive conclusions cannot be drawn regarding the use of cinnamon as an antidiabetic therapy, it does possess antihyperglycaemic properties and potential to reduce postprandial blood glucose levels. Further research is required to confirm a possible correlation between baseline FBG and blood glucose reduction and to assess the potential to reduce pathogenic diabetic complications with cinnamon supplementation. [source] The Livelihoods Gap: Responding to the Economic Dynamics of Vulnerability in SomaliaDISASTERS, Issue 1 2002Andre Le Sage A ,livelihoods gap' has become evident in international aid delivery to Somalia. Existing aid interventions do not address the economic dynamics of vulnerability resulting from Somalia's long history of predatory development and asset stripping. To prevent poor households' regular return to sub-subsistence income levels after a brief period of plenty, this paper argues that aid agencies should reorient and expand existing interventions to assist poor households to capitalise on temporary improvements in environmental and security conditions. As a corollary to emergency relief and efforts to construct state institutions, it is necessary to devise country-wide interventions that will rebuild household asset bases by protecting savings during times of stress and ensuring that markets benefit poor producers. [source] Recurrence of intramucosal esophageal adenocarcinoma arising in a former esophagostomy site: a unique case reportDISEASES OF THE ESOPHAGUS, Issue 6 2009J. M. Leers SUMMARY., A 75-year-old male with a long history of gastroesophageal reflux symptoms developed adenocarcinoma proximally within a long segment of Barrett's esophagus. He was taken for esophagectomy and gastric pull-up, but intraoperatively, he was found to have a marginal blood supply in the gastric tube. A temporary left-sided esophagostomy was created with the gastric tube sutured to the left sternocleidomastoid muscle in the neck. Pathology showed an intramucosal adenocarcinoma, limited to the muscularis mucosa with surrounding high-grade dysplasia and intestinal metaplasia. The proximal esophageal margin showed no tumor cells, but there was low-grade dysplasia within Barrett's esophagus. He was reconstructed after several months, and 2 years after reconstruction, the patient noticed a nodule at the former esophagostomy site. Biopsy revealed an implant metastasis of esophageal adenocarcinoma. Here, we review the literature and discuss the possible etiology. [source] Conifers as invasive aliens: a global survey and predictive frameworkDIVERSITY AND DISTRIBUTIONS, Issue 5-6 2004David M. Richardson ABSTRACT We summarize information on naturalized and invasive conifers (class Pinopsida) worldwide (data from 40 countries, some with remote states/territories), and contrast these findings with patterns for other gymnosperms (classes Cycadopsida, Gnetopsida and Ginkgoopsida) and for woody angiosperms. Eighty conifer taxa (79 species and one hybrid; 13% of species) are known to be naturalized, and 36 species (6%) are ,invasive'. This categorization is based on objective and conservative criteria relating to consistency of reproduction, distance of spread from founders, and degree of reliance on propagules from the founder population for persistence in areas well outside the natural range of species. Twenty-eight of the known invasive conifers belong to one family (Pinaceae) and 21 of these are in one genus (Pinus). The Cupressaceae (including Taxodiaceae) has six known invasive species (4%) in four genera, but the other four conifer families have none. There are also no known invasive species in classes Cycadopsida, Gnetopsida or Ginkgoopsida. No angiosperm family comprising predominantly trees and shrubs has proportionally as many invasive species as the Pinaceae. Besides the marked taxonomic bias in favour of Pinaceae, and Pinus in particular, invasiveness in conifers is associated with a syndrome of life-history traits: small seed mass (< 50 mg), short juvenile period (< 10 year), and short intervals between large seed crops. Cryptomeria japonica, Larix decidua, Picea sitchensis, Pinus contorta, Pinus strobus, and Pseudotsuga menziesii exemplify this syndrome. Many rare and endangered conifer species exhibit opposite characters. These results are consistent with earlier predictions made using a discriminant function derived from attributes of invasive and noninvasive Pinus species. Informative exceptions are species with small seeds (< 4 mg, e.g. Chamaecyparis spp., Pinus banksiana, Tsuga spp. , mostly limited to wet/mineral substrates) or otherwise ,non-invasive' characters (e.g. large seeds, fleshy fruits, e.g. Araucaria araucana, Pinus pinea, Taxus baccata that are dependent on vertebrates for seed dispersal). Most conifers do not require coevolved mutualists for pollination and seed dispersal. Also, many species can persist in small populations but have the genetic and reproductive capacity to colonize and increase population size rapidly. The underlying mechanisms mediating conifer invasions are thus easier to discern than is the case for most angiosperms. Further information is needed to determine the extent to which propagule pressure (widespread dissemination, abundant plantings, long history of cultivation) can compensate for low ,inherent invasiveness'. [source] Testing abundance-range size relationships in European carabid beetles (Coleoptera, Carabidae)ECOGRAPHY, Issue 5 2003D. Johan Kotze Four of the eight hypotheses proposed in the literature for explaining the relationship between abundance and range size (the sampling artifact, phylogenetic non-independence, range position and resource breadth hypotheses) were tested by using atlas data for carabid beetles (Coleoptera, Carabidae) from Belgium, Denmark and the Netherlands. A positive relationship between abundance and partial range size was found in all three countries, and the variation in abundance was lower for widespread species. Analysis of the data did not support three of the proposed hypotheses, but did support the resource breadth hypothesis (species having broader environmental tolerances and being able to use a wider range or resources will have higher local densities and be more widely distributed than more specialised species). Examination of species' characteristics revealed that widespread species are generally large bodied, generalists (species with wide niche breadths occurring in a variety of habitat types) and are little influenced by human-altered landscapes, while species with restricted distributions are smaller bodied, specialists (species with small niche breadths occurring in only one or two habitat types), and favour natural habitat. Landscape alteration may be an important factor influencing carabid abundance and range size in these three countries with a long history of human-induced environmental changes. [source] The age-21 minimum legal drinking age: a case study linking past and current debatesADDICTION, Issue 12 2009Traci L. Toomey ABSTRACT Background The minimum legal drinking age (MLDA) in the United States (U.S.) has raised debate over the past several decades. During the 1970s many states lowered their MLDAs from age 21 to 18, 19, or 20. However, as a result of studies showing that these lower MLDAs were associated with increases in traffic crashes, state-level movements began in the later1970s to return MLDAs to age 21. A new movement has arisen to again lower the MLDA in the U.S. Aim The aim is to discuss this current MLDA debate within the context of the long history of the U.S. MLDA. Methods A search of research articles, websites, and newspaper articles was conducted to identify key messages and influences related to the MLDA movements. Results The complexity of state movements to change their MLDAs is illustrated by the Michigan experience, where strong political forces on both sides of the issue were involved, resulting in the MLDA returning to 21. Because the 21st Constitutional amendment prevents the federal government from mandating a MLDA for all states, a federal policy was proposed to provide incentives for all states to implement age-21 MLDAs. Due largely to strong research evidence, the National Minimum Legal Drinking Age Act was enacted in 1984, stipulating that states set their MLDA to 21 or face loss of federal highway funds. By 1988, all states had an age-21 MLDA. Conclusion Any current debate about the MLDA should be informed by the historical context of this policy and the available research. [source] Diagnostic Implications of Uric Acid in Electroanalytical MeasurementsELECTROANALYSIS, Issue 14 2005Abstract Urate has a long history in clinical analysis and has served as an important diagnostic in a number of contexts. The increasing interest in metabolic syndrome has led to urate being used in combination with a number of other biomarkers in the assessment of cardiovascular risk. The traditional view of urate as principally an interferent in electrochemical measurement is now gradually being replaced with the realization that its measurement could serve as an invaluable secondary (if not primary) marker when monitoring conditions such as diabetes and heart disease. Rather than attempting to wholly exclude urate electrochemistry, many strategies are being developed that can integrate the urate signal within the device architecture such that a range of biomarkers can be sequentially assessed. The present review has sought to rationalize the clinical importance that urate measurements could hold in future diagnostic applications , particularly within near patient testing contexts. The technologies harnessed for its detection and also those previously employed for its removal are reviewed with the aim of highlighting how the seemingly contrasting approaches are evolving to aid the development of new sensing devices for clinical analysis. [source] Residential Segregation Influences on the Likelihood of Ethnic Self-EmploymentENTREPRENEURSHIP THEORY AND PRACTICE, Issue 2 2009Gregory B. Fairchild Geographic and environmental influences on economic action have a long history in managerial research. This paper develops and estimates a model of the potential of a broad set of U.S. racial minority groups to enter self-employment based on individual-level, household-level, and metropolitan area-level factors. The model allows for an analysis of two distinct residential segregation processes on self-employment likelihood. Results indicate that clustering by race has group-specific influences, increasing the likelihood of self-employment for some groups and diminishing for others. Higher levels of racial exposure raise the likelihood of entrepreneurial careers for all groups, but especially for Blacks. [source] Alcohol genetics: will the promise be fulfilled?ADDICTION BIOLOGY, Issue 4 2000Chris Cook Genetic research into alcohol-related problems has a long history, but only with the recent advent of molecular biological techniques does it seem poised to fulfill its promise. While such research might be thought to reinforce views of the inevitability and immutability of drinking problems, there have been bold promises of important developments in our understanding of the aetiology of alcohol misuse, as well as promises of innovations in prevention and treatment. A brief consideration of recent research, and of the possibilities that are now before us, reveals that the promise of increased understanding of the aetiology of alcohol misuse is already being fulfilled. Promises of new preventive and therapeutic interventions, if they also are to be fulfilled, require that a number of practical and ethical issues be addressed. Clinicians, researchers and others in the addictions field need to begin to address the ethical issues that are raised. [source] Differences in personality characteristics between body-modified and non-modified individuals: associations with individual personality traits and their possible evolutionary implicationsEUROPEAN JOURNAL OF PERSONALITY, Issue 7 2007Silke Wohlrab Abstract After a long history of negative stigmatisation, the practices of tattooing and body piercing have become fashionable in the last decade. Today, 10% of the population in modern western societies have some form of body modification. The aim of this study was to quantify the demographic and personality traits of tattooed and pierced individuals and to compare them with a control group of individuals without body modifications. These comparisons are based on questionnaires completed by 359 individuals that investigate the details of body modification, and which incorporate five personality scales. We describe several sex differences in ornament style and location. We found no relevant differences between modified and non-modified individuals in relation to demographic variables. This indicates that some of the traditional attitudes towards tattoos and piercings appear to be outdated. However, we found striking differences in personality traits which suggest that body-modified individuals are greater sensation seekers and follow a more unrestricted mating strategy than their non-modified contemporaries. We discuss these differences in light of a potential signalling function of tattoos and piercings in the mating context. Copyright © 2007 John Wiley & Sons, Ltd. [source] Beneficial lactobacilli in food and feed: long-term use, biodiversity and proposals for specific and realistic safety assessmentsFEMS MICROBIOLOGY REVIEWS, Issue 4 2006Marion Bernardeau Abstract Lactobacilli have played a crucial role in the production of fermented products for millennia. Their probiotic effects have recently been studied and used in new products. Isolated cases of lactobacillemia have been reported in at-risk populations, but lactobacilli present an essentially negligible biological risk. We analyzed the current European guidelines for safety assessment in food/feed and conclude that they are not relevant for the Lactobacillus genus. We propose new specific guidelines, beginning by granting a ,long-standing presumption of safety' status to Lactobacillus genus based on its long history of safe use. Then, based on the available body of knowledge and intended use, only such tests as are useful will be necessary before attributing ,qualified presumption of safety' status. [source] Genetic improvement of processes yielding microbial productsFEMS MICROBIOLOGY REVIEWS, Issue 2 2006Jose L. Adrio Abstract Although microorganisms are extremely good in presenting us with an amazing array of valuable products, they usually produce them only in amounts that they need for their own benefit; thus, they tend not to overproduce their metabolites. In strain improvement programs, a strain producing a high titer is usually the desired goal. Genetics has had a long history of contributing to the production of microbial products. The tremendous increases in fermentation productivity and the resulting decreases in costs have come about mainly by mutagenesis and screening/selection for higher producing microbial strains and the application of recombinant DNA technology. [source] The ecology and agronomy of Miscanthus sinensis, a species important to bioenergy crop development, in its native range in Japan: a reviewGCB BIOENERGY, Issue 2 2009J. RYAN STEWART Abstract Among several candidate perennial taxa, Miscanthus×giganteus has been evaluated and promoted as a promising bioenergy crop. Owing to several limitations, however, of the sterile hybrid, both at the taxon and agronomic production levels, other options need to be explored to not only improve M. ×giganteus, which was originally collected in Japan, but to also consider the development of other members of its genus, including Miscanthus sinensis, as bioenergy crops. Indeed, there is likely much to be learned and applied to Miscanthus as a bioenergy crop from the long history of intensive interaction between humans and M. sinensis in Japan, which in some regions of the country spans several thousand years. Combined with its high amount of genetic variation, stress tolerance, biotic interactions with fauna, and function as a keystone species in diverse grasslands and other ecosystems within its native range, the unique and extensive management of M. sinensis in Japan as a forage grass and building material provides agronomists, agroecologists, and plant breeders with the capability of better understanding this species in terms of potential contribution to bioenergy crop development. Moreover, the studies described in this review may serve as a platform for future research of Miscanthus as a bioenergy crop in other parts of the world. [source] USER INNOVATION AND CREATIVE CONSUMPTION IN JAPANESE CULTURE INDUSTRIES: THE CASE OF AKIHABARA, TOKYOGEOGRAFISKA ANNALER SERIES B: HUMAN GEOGRAPHY, Issue 3 2010Jakob Nobuoka ABSTRACT. The consumption and export of material and immaterial commodities based upon Japanese popular culture is rapidly growing and continually finds new fans all around the world. In this article, it is suggested that some of the competitiveness of these unique cultural phenomena can be traced to the very dense and vivid area of Akihabara in Tokyo. Its long history as an electronic retail district and a more recent influx of firms and shops focused on popular culture has created a strong place brand that continues to mark Akihabara as the capital of Japanese cultural industries. It is a space where different consumers, specialist subcultures and firms and their products can interact. The area functions as a hub were ideas and values are exchanged, tested and promoted. The article argues that research on innovation milieus must take account of the role of users and their relation to place. [source] Regional Devolution and Regional Economic Success: Myths and Illusions about PowerGEOGRAFISKA ANNALER SERIES B: HUMAN GEOGRAPHY, Issue 2 2006Ray Hudson Abstract The proposition that regional devolution in and of itself will lead to economic success has become deeply embedded in beliefs and policy discourses about the determinants of regional prosperity, and in turn has led to political demands for such devolution. In this paper I seek critically to examine such claims, using the case of the north-east of England as the setting for this examination. The paper begins with some introductory comments on concepts of power, regions, the reorganization of the state and of multi-level governance, and governmentality, which help in understanding the issues surrounding regional devolution. I then examine the ways in which north-east England was politically and socially constructed as a particular type of region, with specific problems, in the 1930s , a move that has had lasting significance up until the present day. Moving on some six decades, I then examine contemporary claims about the relationship between regional devolution and regional economic success, which find fertile ground in the north-east precisely due to its long history of representation as a region with a unified regional interest. I then reflect on the processes of regional planning, regional strategies and regional devolution, and their relationship to regional economic regeneration. A brief conclusion follows, emphasizing that questions remain about the efficacy of the new governmentality and about who would be its main beneficiaries in the region. The extent to which devolution would actually involve transferring power to the region and the capacity of networked forms of power within the region to counter the structural power of capital and shape central state policies remains unclear. [source] Teaching and Learning Guide for: Memoryscape: How Audio Walks Can Deepen Our Sense of Place by Integrating Art, Oral History and Cultural GeographyGEOGRAPHY COMPASS (ELECTRONIC), Issue 5 2008Toby Butler Author's Introduction This article is concerned with the history and practice of creating sound walks or ,memoryscapes': outdoor trails that use recorded sound and spoken memory played on a personal stereo or mobile media to experience places in new ways. It is now possible to cheaply and easily create this and other kinds of located media experience. The development of multi-sensory-located media (,locedia') presents some exciting opportunities for those concerned with place, local history, cultural geography and oral history. This article uses work from several different disciplines (music, sound art, oral history and cultural geography) as a starting point to exploring some early and recent examples of locedia practice. It also suggests how it might give us a more sophisticated, real, embodied and nuanced experience of places that the written word just can not deliver. Yet, there are considerable challenges in producing and experiencing such work. Academics used to writing must learn to work in sound and view or image; they must navigate difficult issues of privacy, consider the power relations of the outsider's ,gaze' and make decisions about the representation of places in work that local people may try and have strong feelings about. Creating such work is an active, multi-sensory and profoundly challenging experience that can offer students the chance to master multi-media skills as well as apply theoretical understandings of the histories and geographies of place. Author Recommends 1.,Perks, R., and Thomson, A. (2006). The oral history reader, 2nd ed. London: Routledge. This is a wonderful collection of significant writing concerned with oral history. Part IV, Making Histories features much of interest, including a thought-provoking paper on the challenges of authoring in sound rather than print by Charles Hardy III, and a moving interview with Graeme Miller, the artist who created the Linked walk mentioned in the memoryscape article. These only feature in the second edition. 2.,Cresswell, T. (2004). Place: a short introduction. Oxford, UK: Blackwell. A refreshingly clear and well-written guide to the different theoretical takes on what makes places , a good starting point for further reading. 3.,Carlyle, A. (ed.). (2008). Autumn leaves: sound and the environment in artistic practice. Paris, France: Double Entendre. This is a collection of short essays and examples of located sonic media art; it includes interviews with practitioners and includes Hildegard Westekamp's Soundwalking, a practical guide to leading students on a mute walk. Lots of thought provoking, applied reading material for students here. 4.,Blunt, A., et al. (eds) (2003). Cultural geography in practice. London: Arnold. A great book for undergraduate and postgraduate students , concepts explained and lots of examples of actually doing cultural geography. The chapter on mapping worlds by David Pinder is particularly useful in this context. 5.,Pinder, D. (2001). Ghostly footsteps: voices, memories and walks in the city. Ecumene 8 (1), pp. 1,19. This article is a thoughtful analysis of a Janet Cardiff sound walk in Whitechapel, East London. Online Materials http://www.memoryscape.org.uk This is my project website, which features two online trails, Dockers which explores Greenwich and the memories of the London Docks that are archived in the Museum of London, and Drifting which is a rather strange experiment-combining physical geography and oral history along the Thames at Hampton Court, but still makes for an interesting trail. Audio, maps and trails can be downloaded for free, so students with phones or iPods can try the trails if you are within reach of Surrey or London. The site features an online version, with sound-accompanying photographs of the location. http://www.portsofcall.org.uk This website has three more trails here, this time of the communities surrounding the Royal Docks in East London. The scenery here is very dramatic and anyone interested in the regeneration of East London and its impact on local communities will find these trails interesting. Like Dockers, the walks feature a lot of rare archive interviews. This project involved a great deal of community interaction and participation as I experimented with trying to get people involved with the trail-making process. The site uses Google maps for online delivery. http://www.soundwalk.com This New York-based firm creates exceptionally high-quality soundwalks, and they are well worth the money. They started by producing trails for different districts of New York (I recommend the Bronx Graffiti trail) and have recently made trails for other cities, like Paris and Varanassi in India. http://www.mscapers.com This website is run by Hewlett Packard, which has a long history of research and development in located media applications. They currently give free licence to use their mscape software which is a relatively easy to learn way of creating global positioning system-triggered content. The big problem is that you have to have a pricey phone or personal digital assistant to run the software, which makes group work prohibitively expensive. But equipment prices are coming down and with the new generations of mobile phones developers believe that the time when the player technology is ubiquitous might be near. And if you ask nicely HP will lend out sets of equipment for teaching or events , fantastic if you are working within reach of Bristol. See also http://www.createascape.org.uk/ which has advice and examples of how mscape software has been used for teaching children. Sample Syllabus public geography: making memoryscapes This course unit could be adapted to different disciplines, or offered as a multidisciplinary unit to students from different disciplines. It gives students a grounding in several multi-media techniques and may require support/tuition from technical staff. 1.,Introduction What is a located mediascape, now and in the future? Use examples from resources above. 2.,Cultural geographies of site-specific art and sound Theories of place; experiments in mapping and site-specific performance. 3.,Walk activity: Westergard Hildekamp , sound walk, or one of the trails mentioned above The best way , and perhaps the only way , to really appreciate located media is to try one in the location they have been designed to be experienced. I would strongly advise any teaching in this field to include outdoor, on-site experiences. Even if you are out of reach of a mediascape experience, taking students on a sound walk can happen anywhere. See Autumn Leaves reference above. 4.,Researching local history An introduction to discovering historical information about places could be held at a local archive and a talk given by the archivist. 5.,Creating located multimedia using Google maps/Google earth A practical exercise-based session going through the basics of navigating Google maps, creating points and routes, and how to link pictures and sound files. 6.,Recording sound and oral history interviews A practical introduction to the techniques of qualitative interviewing and sound recording. There are lots of useful online guides to oral history recording, for example, an online oral history primer http://www.nebraskahistory.org/lib-arch/research/audiovis/oral_history/index.htm; a more in depth guide to various aspects of oral history http://www.baylor.edu/oral%5fhistory/index.php?id=23566 or this simple oral history toolkit, with useful links to project in the North of England http://www.oralhistorynortheast.info/toolkit/chapter1.htm 7.,Sound editing skills Practical editing techniques including working with clips, editing sound and creating multi-track recordings. The freeware software Audacity is simple to use and there are a lot of online tutorials that cover the basics, for example, http://www.wikieducator.org/user:brentsimpson/collections/audacity_workshop 8.,Web page design and Google maps How to create a basic web page (placing pictures, text, hyperlinks, buttons) using design software (e.g. Dreamweaver). How to embed a Google map and add information points and routes. There is a great deal of online tutorials for web design, specific to the software you wish to use and Google maps can be used and embedded on websites free for non-profit use. http://maps.google.com/ 9,and 10. Individual or group project work (staff available for technical support) 11.,Presentations/reflection on practice Focus Questions 1What can sound tell us about the geographies of places? 2When you walk through a landscape, what traces of the past can be sensed? Now think about which elements of the past have been obliterated? Whose past has been silenced? Why? How could it be put back? 3Think of a personal or family story that is significant to you. In your imagination, locate the memory at a specific place. Tell a fellow student that story, and describe that place. Does it matter where it happened? How has thinking about that place made you feel? 4What happens when you present a memory of the past or a located vision of the future in a present landscape? How is this different to, say, writing about it in a book? 5Consider the area of this campus, or the streets immediately surrounding this building. Imagine this place in one of the following periods (each group picks one): ,,10,000 years ago ,,500 years ago ,,100 years ago ,,40 years ago ,,last Thursday ,,50 years time What sounds, voices, stories or images could help convey your interpretation of this place at that time? What would the visitor hear or see today at different points on a trail? Sketch out an outline map of a located media trail, and annotate with what you hear/see/sense at different places. Project Idea small group project: creating a located mediascape Each small group must create a located media experience, reflecting an aspect of the history/geography/culture of an area of their choosing, using the knowledge that they have acquired over the course of the semester. The experience may be as creative and imaginative as you wish, and may explore the past, present or future , or elements of each. Each group must: ,,identify an area of interest ,,research an aspect of the area of the groups choosing; this may involve visiting local archives, libraries, discussing the idea with local people, physically exploring the area ,,take photographs, video or decide on imagery (if necessary) ,,record sound, conduct interviews or script and record narration ,,design a route or matrix of media points The final project must be presented on a website, may embed Google maps, and a presentation created to allow the class to experience the mediascape (either in the classroom or on location, if convenient). The website should include a brief theoretical and methodological explanation of the basis of their interpretation. If the group cannot be supported with tuition and support in basic website design or using Google mapping with sound and imagery, a paper map with locations and a CD containing sound files/images might be submitted instead. For examples of web projects created by masters degree students of cultural geography at Royal Holloway (not all sound based) see http://www.gg.rhul.ac.uk/MA/web-projects.html [source] Haemate® P von Willebrand factor/factor VIII concentrate: 25 years of clinical experienceHAEMOPHILIA, Issue 2008W. SCHRAMM Summary., Although von Willebrand disease (VWD) has a very long history, our understanding and treatment of the bleeding disorder has only evolved during the past 50 years or so. It was not until the 1920s that VWD was first recognized as a disease separate from that of classical haemophilia. It then took another 30 years before the first effective treatment was developed. Since then, the medical management of VWD has evolved considerably, but not without its ups and downs. One of the key milestones in the evolution of the treatment of VWD was the development of Haemate® P/Humate-P® (CSL Behring) , the first virus-inactivated factor VIII plasma product. For 25 years, this concentrate has demonstrated excellent clinical efficacy and safety for patients with VWD and for those with haemophilia. This article provides an historical overview of the early landmark efforts to ensure a safe plasma-derived replacement product and outlines the clinical evolution in the use of Haemate® P. [source] The successful use of maggots in necrotizing fasciitis of the neck: A case reportHEAD & NECK: JOURNAL FOR THE SCIENCES & SPECIALTIES OF THE HEAD AND NECK, Issue 8 2004Simon F. Preuss MD Abstract Background. The use of maggots to digest necrotic tissue as a form of wound debridement has a long history in medicine. Necrotizing fasciitis of the neck has a high mortality rate despite aggressive surgical and medical intervention. The use of maggots in this disease has been reported only once before. Methods. We report the case of a 73-year-old woman, who underwent neck dissection and had necrotizing fasciitis of the neck develop shortly after. After initial surgical wound debridement, we used maggots as a biosurgical method for further debridement. A net containing 100 maggots (Biobag; BioMonde, Germany) was used. Results. Daily wound dressing showed rapid improvement of the wound; 4 days after beginning treatment, the wound was free of necroses. Conclusion. In this case, we could avoid repeated surgical wound debridement with the use of sterile maggots. The frequently rapid progression of necrotizing fasciitis could be well controlled. © 2004 Wiley Periodicals, Inc. Head Neck26: 747,750, 2004 [source] Estimating the monetary value of health care: lessons from environmental economicsHEALTH ECONOMICS, Issue 1 2003Nick Hanley In the recent past, considerable effort in health economics has been made on applying stated preference methods such as contingent valuation and choice experiments. Despite this increased use, there is still considerable scepticism concerning the value of these approaches. The application of contingent valuation in environmental economics has a long history and has been widely accepted. Whilst choice experiments were introduced to the environmental and health economics literature at a similar time, the wider acceptance of monetary measures of benefit in environmental economics has meant that they have also been more widely applied. The purpose of this paper is to identify some of the key issues and debates that have taken place in the environmental economics literature, summarise the state of the art with respect to these issues, and consider how health economists have addressed these issues. Important areas for future research in health economics are identified. Copyright © 2002 John Wiley & Sons, Ltd. [source] The Advent of the Secret Ballot in Britain and France, 1789,1914: From Public Assembly to Private CompartmentHISTORY, Issue 308 2007MALCOLM CROOK These days the secret ballot is taken for granted and it is often seen as the natural complement of universal, democratic suffrage. Its emergence, however, was just as contested and varied as the franchise and raised similar issues concerning the nature and practice of citizenship. This article focuses on the emergence of the secret ballot in Britain and France, two countries with a long history of parliamentary and local elections. In Britain, the secret ballot was introduced in 1872, while in France, which introduced universal male suffrage in 1848, it was as late as 1913 before envelope and polling booth rendered the vote completely secure. This study documents the varied polling practices employed in both countries prior to the onset of the secret ballot. It also highlights the contentious nature of polling reform. For some, the secret ballot was regarded as a means of safeguarding electoral independence and eliminating corruption. Others, including radicals, argued quite the opposite: that secret voting was an affront to honourable, public-spirited citizenship. In the end, full secrecy was achieved as part of the broader process of domesticating and disciplining the exercise of a mass franchise. [source] Beyond the enterprise: trade union representation of freelances in the UKHUMAN RESOURCE MANAGEMENT JOURNAL, Issue 2 2004Edmund Heery Interest has grown in the methods that trade unions can use to organise and represent the substantial proportion of the workforce engaged in ,contingent work'. This article examines trade union representation of self-employed freelances in the UK. Empirical material is presented from case studies of the media and entertainment unions, with their long history of representing freelances, and more recently established unions representing freelance tour guides, interpreters and translators. The analysis indicates that there is a distinctive form of freelance unionism in the UK which is distinguished by its emphasis on organising and representing workers in the external labour market where they seek work and develop a mobile career. This orientation ,beyond the enterprise' distinguishes freelance unionism from the dominant form of unionism in Britain. [source] Union recognition in Britain's offshore oil and gas industry: implications of the Employment Relations Act 1999INDUSTRIAL RELATIONS JOURNAL, Issue 4 2004Charles Woolfson ABSTRACT The Employment Relations Act 1999 (ERA) has provided trade unions in the UK with new opportunities for achieving recognition. After a long history of anti-unionism in the offshore oil and gas industry, employers have voluntarily ceded recognition to Trades Union Congress (TUC)-affiliated trade unions. The legitimacy of this recognition process has been contested by the non-TUC Offshore Industry Liaison Committee (OILC), an offshore workers' union, seeking to act as a recognised bargaining agent. The ERA may be promoting ,business friendly' agreements at the expense of claims to recognition of other bargaining agents and of democratic employee choice. [source] | ||||||||||||||||||||||||||||||||||||||||||||||