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logMAR Visual Acuity (logmar + visual_acuity)
Selected Abstracts4125: Phenotypic variability in association with mutation in RDS/peripherinACTA OPHTHALMOLOGICA, Issue 2010GE HOLDER Purpose To report the clinical and electrophysiological findings associated with autosomal dominant maculopathy caused by mutations in Rds/peripherin. Methods Fifty three individuals with autosomal dominant macular dystrophy and a confirmed molecular diagnosis of Rds/peripherin mutation were ascertained between January 2002 and December 2008. International-standard pattern and full-field electroretinograms (PERG; ERG) were performed in 38 cases. Electro-oculograms (EOG) were performed in 25 cases. Results Fourteen different mutations were identified in the Rds/peripherin gene; 4 of which were novel. Twenty four (45%) patients had the common p.Arg172 Trp allele. The mean age at the time of first symptoms and at diagnosis was 35.0+/- 2.4 and 47.1 +/- 1.5 years old [SEM] respectively. Mean LogMAR visual acuity at presentation was 0.5+/- 0.08 [SEM]. Fundus phenotypes included central atrophy (19 cases), pattern dystrophy (10 cases), maculopathy with flecks (5 cases), and adult vitellifom dystrophy (4 cases). Pattern ERG P50 reduction was seen in 75 of 76 eyes; the majority having undetectable or residual responses, including some cases with preserved visual acuity. ERG ranged from normal to severe reduction in both cone and rod driven responses and were not predictable either from the fundus appearance or from the specific mutation in Rds/peripherin; on addition, marked intra-familial variation could be noted. Conclusion Mutations in the Rds/peripherin gene result in a wide variety of fundus and functional phenotypes. The same mutation can result in profoundly different phenotypes, even within family members. [source] Poor recognition of the UK minimum driving vision standard by motorists attending optometric practiceOPHTHALMIC AND PHYSIOLOGICAL OPTICS, Issue 3 2007Jonathan S. Pointer Abstract Purpose:, To evaluate the current level of recollection of the vehicle number plate viewing distance in a group of motorists. Knowledge of this distance is required to self-check compliance with the UK legal minimum driving vision standard. Methods:, A cohort of 480 motorists aged ,17 years attending optometric practice for a routine sight test agreed to participate in a short verbal survey. They were asked whether they could state the current UK statutory vehicle number plate viewing distance as specified in the Highway Code. Also recorded were each motorist's high contrast logMAR visual acuity, whether or not an optical prescription was habitually worn when driving, and brief demographic details (age, gender). Results:, No statistically significant gender-based difference was present in age distribution, mean logMAR binocular acuity, or age and number (proportion) of motorists who habitually wore a refractive correction when driving. The level of mean binocular acuity was uniformly good (<0.0 logMAR, or better than 6/6 Snellen). However, the recollection by respondents of the statutory viewing distance was poor: only 5% were able to state correctly the current distance (20 m), and 22% recalled the previous (20.5 m/67 ft) or the original (22.9 m/75 ft) statutory distance. Of the remainder, 28% underestimated and 45% overestimated the distance. A statistically significant gender-based difference (p = 0.01) between the recollections of non-prescription wearers became marked (p = 0.001) for habitual wearers, in which latter case the median value and range of estimates by female motorists was greater than their male counterparts. Conclusions:, The level of recognition by these motorists of the viewing distance necessary to satisfy the legal minimum vision standard required for driving on UK roads was low and comparable to the levels recorded in two similar surveys undertaken by other authors 10 and 20 years ago. An inexpensive and easily implemented publicity innovation is suggested which could help improve driver appreciation of the statutory distance and promote compliance with the legal vision standard. [source] Objective predictors of subjective visual function for different age-related cataract morphologiesOPHTHALMIC AND PHYSIOLOGICAL OPTICS, Issue 6 2002N. Hakim-Banan Purpose:, To find objective chart tests that give a measure of visual function in the different age-related cataract morphological groups and can be applied in a clinical setting. Methods:, Subjects with age-related cataract (N = 33) were recruited to the study from both private optometric practice and a hospital eye department. All subjects underwent LOCS III grading of their cataract and had their functional vision assessed using the VF-14 questionnaire. High (96%) and low (16%) contrast logMAR visual acuity were measured together with Pelli,Robson contrast sensitivity. A stepwise linear regression was then performed on the data to find significant predictors for VF-14 in the three age-related cataract morphological groups as well as in a mixed group. Results:, Low contrast logMAR visual acuity was a significant predictor of VF-14 in the cortical (p = 0.014) and nuclear (p = 0.024) subgroups. For the mixed morphological group both high and low contrast visual acuity were significant predictors (p < 0.03). There were only three subjects with pure posterior subcapsular cataract and so no meaningful analysis could be performed. Conclusions:, Low contrast logMAR visual acuity may be a better predictor of visual function in cortical and nuclear cataract compared with high contrast logMAR visual acuity or Pelli,Robson contrast sensitivity. [source] Macular function after intravitreal triamcinolone acetonide injection for diabetic macular oedemaACTA OPHTHALMOLOGICA, Issue 5 2010Murat Karacorlu Abstract. Purpose:, We aimed to evaluate the effect of intravitreal triamcinolone acetonide (IVTA) on macular function in patients with diabetic macular oedema (DMO). Methods:, Eleven eyes in 11 patients with DMO were enrolled. In each eye, at baseline and at 30 days after IVTA injection, logMAR visual acuity (VA), macular sensitivity, fixation stability and fixation location by MP-1 microperimetry and optical coherence tomography (OCT) foveal thickness were assessed. Results:, Thirty days after IVTA injection, eyes with DMO showed a significant (p < 0.001) reduction in foveal thickness and significant (p < 0.01) increases in logMAR VA and MP-1 retinal sensitivity (p < 0.001). There was also significant (p = 0.046) improvement in fixation location and some improvement in fixation stability, although the latter was not significant (p = 0.08). Conclusions:, In eyes with DMO, short-term improvement in retinal sensitivity and fixation properties can be achieved by IVTA injection. [source] Quantitative assessment of retinal thickness in diabetic patients with and without clinically significant macular edema using optical coherence tomographyACTA OPHTHALMOLOGICA, Issue 3 2001Chang-Sue Yang ABSTRACT. Purpose: To assess patients with diabetic macular edema quantitatively using optical coherence tomography (OCT). Methods: OCT was performed in 14 eyes with diabetic retinopathy and ophthalmoscopic evidence of clinically significant macular edema (CSME) and in 19 diabetic eyes without CSME. Retinal thickness was computed from the tomograms at fovea and other 36 locations throughout the macula. Results: The mean±standard deviation foveal thickness was 255.6±138.9 ,m in eyes with CSME, and 174.6±38.2 ,m in eyes without CSME (p=0.051). Within 2000 ,m of the center of the macula, eyes with CSME had significantly thicker retina in the inferior quadrant than those without CSME (p<0.01). The foveal thickness was correlated with logMAR visual acuity (,=0.68, p<0.01). OCT identified sponge-like retinal swelling and/or cystoid macular edema in 11 (58%) eyes without CSME, and in 12 (86%) eyes with CSME. Conclusions: Criteria of CSME seem to be insufficient in really identifying macular edema. OCT may be more sensitive than a clinical examination in assessing diabetic macular edema and is a quantitative tool for documenting changes in macular thickening. [source] Visual outcomes following vitrectomy and peeling of epiretinal membraneCLINICAL & EXPERIMENTAL OPHTHALMOLOGY, Issue 4 2005James G Wong MMed Abstract Background:, Visual outcomes of patients following vitrectomy and peeling of visually significant epiretinal membranes were assessed to determine the influence of specific perioperative factors and surgical complications on final visual acuity and functional vision. Methods:, In an unmatched, consecutive surgical series, vitrectomy and membrane peeling were performed on 125 eyes of 123 patients with visually significant macular epiretinal membranes. Patients were followed for 6,36 months. Visual outcome measures included postoperative logMAR visual acuity, change in visual acuity and functional vision tasks evaluated by questionnaire. Perioperative factors including duration of symptoms, preoperative visual acuity, aetiology, membrane type and leakage on fundal fluorescein angiogram were correlated with final visual outcomes. Results:, Visual acuity improved by a mean of 0.31 ± 0.21 units (three lines of vision). In 104 cases (83%), visual acuity improved in patients by two lines or more, with 20 cases (16%) having unchanged acuity and one case (1%) having worse acuity. Ninety-three per cent of interviewed cases reported improvement in functional vision, especially reduction of distortion. Cataract was observed in 52 cases (52% of phakic eyes) postoperatively compared with 19 cases (19%) preoperatively. Postoperative visual acuity correlated with preoperative visual acuity. Patients with worse preoperative vision recorded greater visual improvement following surgery. No other perioperative factors were found to have a prognostic value in this study. Conclusion:, Epiretinal membrane peeling improves vision in the majority of patients with significant symptoms, even if preoperative visual acuity is not substantially reduced. Surgery improves functional vision including metamorphopsia not measurable by visual acuity, and thus assessment of functional vision should be included in surgical case planning. [source] | ||||||||||