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Load Used (load + used)
Selected AbstractsResistance and Agility Training Reduce Fall Risk in Women Aged 75 to 85 with Low Bone Mass: A 6-Month Randomized, Controlled Trial,JOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 5 2004Teresa Liu-Ambrose PhD Objectives: To compare the effectiveness of group resistance and agility-training programs in reducing fall risk in community-dwelling older women with low bone mass. Design: A randomized, controlled, single-blind 25-week prospective study with assessments at baseline, midpoint, and trial completion. Setting: Community center. Participants: Community-dwelling women aged 75 to 85 with low bone mass. Intervention: Participants were randomly assigned to one of three groups: resistance training (n=32), agility training (n=34), and stretching (sham) exercises (n=32). The exercise classes for each study arm were held twice weekly. Measurements: The primary outcome measure was fall risk (derived from weighted scores from tests of postural sway, reaction time, strength, proprioception, and vision), as measured using a Physiological Profile Assessment (PPA). Secondary outcome measures were ankle dorsiflexion strength, foot reaction time, and Community Balance and Mobility Scale score. Results: Attendance at the exercise sessions for all three groups was excellent: resistance training (85.4%), agility training (87.3%), and stretching program (78.8%). At the end of the trial, PPA fall-risk scores were reduced by 57.3% and 47.5% in the resistance and agility-training groups, respectively, but by only 20.2% in the stretching group. In the resistance and agility groups, the reduction in fall risk was mediated primarily by improved postural stability, where sway was reduced by 30.6% and 29.2%, respectively. There were no significant differences between the groups for the secondary outcomes measures. Within the resistance-training group, reductions in sway were significantly associated with improved strength, as assessed using increased squat load used in the exercise sessions. Conclusion: These findings support the implementation of community-based resistance and agility-training programs to reduce fall risk in older women with low bone mass. Such programs may have particular public health benefits because it has been shown that this group is at increased risk of falling and sustaining fall-related fractures. [source] Virus load dynamics of individual CMV-genotypes in lung transplant recipients with mixed-genotype infectionsJOURNAL OF MEDICAL VIROLOGY, Issue 8 2008Irene Görzer Abstract Human cytomegalovirus (CMV) is a major cause of disease and transplant dysfunction in lung transplant recipients. Simultaneous emergence of more than one CMV-genotype can occur, and appears to be disadvantageous for the patient. In this study, the dynamics of individual CMV-genotypes in blood and lung was assessed within mixed CMV-genotype populations emerging after lung transplantation. In 69 plasma and 76 bronchoalveolar lavage samples of 16 lung transplant recipients with mixed CMV-genotype infections within the first year posttransplantation each of the major glycoprotein B (gB) and glycoprotein H (gH) genotypes was selectively quantified by genotype-specific quantitative TaqMan assays. The data obtained revealed that individually different genotype dynamics occurred for the individual patients and that the relative levels of the genotypes to each other may change over time. The quantitative development was independent of the specific gB,gH-genotype. In 10 of the 16 lung recipients the patient's individual genotype composition was the same in blood and lung. Genotype development during the follow-up was influenced by antiviral treatment. These data show for the first time that the CMV load used as diagnostic tool after transplantation is not always a constant entity but reflects the sum of the individual CMV-genotype dynamics developing over time. J. Med. Virol. 80:1405,1414, 2008. © 2008 Wiley-Liss, Inc. [source] Electrical Characteristics of an Electronic Control Device Under a Physiologic Load: A Brief ReportPACING AND CLINICAL ELECTROPHYSIOLOGY, Issue 3 2010DONALD M. DAWES M.D. Background:,Law enforcement officers use electronic control devices (ECDs), such as the TASER X26 (TASER International, Inc., Scottsdale, AZ, USA), to control resisting subjects. Some of the debate on the safety of the devices has centered on the electrical characteristics of the devices. The electrical characteristics published by TASER International have historically based on discharges into a 400 , resistor. There are no studies that the authors are aware of that report the electrical characteristics under a physiologic load. In this study, we make an initial attempt to determine the electrical characteristics of the TASER X26 during a 5-second exposure in human volunteers. Methods:,Subjects received an exposure to the dry, bare chest (top probe), and abdomen (bottom probe) with a standard TASER X26 in the probe deployment mode for 5 seconds. There were 10,11 pulse captures during the 5 seconds. Resistance was calculated using the sum of the absolute values of the instantaneous voltage measurements divided by the sum of the absolute values of the instantaneous current measurements (Ohm's Law). Results:,For the eight subjects, the mean spread between top and bottom probes was 12.1 inches (30.7 cm). The mean resistance was 602.3 ,, with a range of 470.5,691.4 ,. The resistance decreased slightly over the 5-second discharge with a mean decrease of 8.0%. The mean rectified charge per pulse was 123.0 ,C. The mean main phase charge per pulse was 110.5 ,C. The mean pulse width was 126.9 ,s. The mean voltage per pulse was 580.1 V. The mean current per pulse was 0.97 A. The average peak main phase voltage was 1899.2 V and the average peak main phase current was 3.10 A. Conclusions:,The mean tissue resistance was 602.3 , in this study. There was a decrease in resistance of 8% over the 5-second exposure. This physiologic load is different than the 400 , laboratory load used historically by the manufacturer. We recommend future characterization of these devices use a physiologic load for reporting electrical characteristics. We also recommend that all the electrical characteristics be reported. (PACE 2010; 33:330,336) [source] An experimental approach to executive fingerprinting in young childrenINFANT AND CHILD DEVELOPMENT, Issue 2 2002Michael Beveridge Abstract This paper presents a methodology designed to investigate the potential independence of memory and inhibition as component processes of executive function (EF) in young school age children. Two groups of 30 6- and 8-year-olds were tested on three EF tasks; a continuous performance test, a Stroop-like task, and a start/stop task. Each task had four conditions, which systematically combined two levels of memory load and two levels of inhibitory demand. This design enabled us to examine whether, within the range of memory and inhibitory loads used, the effects of memory and inhibitory demands on these tasks were additive and independent, or instead interacted with one another. Analyses of both errors and response times across the three tasks provided no positive evidence for the view that memory and inhibition are inter-dependent processes. The tasks proved sensitive to age, with the 8-year-olds generally outperforming the 6-year-olds. In addition, effects of the memory and inhibition manipulations were observed. However, there was little evidence that memory load and inhibitory demand interacted in the way that would be expected if these factors draw on a shared pool of common executive resources. Copyright © 2002 John Wiley & Sons, Ltd. [source] | ||||||||||