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Limb Infusion (limb + infusion)

Distribution by Scientific Domains
Medical Sciences100%

Kinds of Limb Infusion

  • isolated limb infusion
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    Selected Abstracts

    Isolated limb infusion with cytotoxic agent for treatment of localized refractory cutaneous T-cell lymphoma

    INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, Issue 4 2006
    E. ELHASSADI
    Summary We described a 57-yr-old male diagnosed with cutaneous T-cell lymphoma that had failed multiple treatment options, as his disease was mainly confined to one limb. We attempted a novel approach in this condition using a technique of intra-arterial limb infusion with cytotoxic agent Melphalan (ILI) which has been proven beneficial in management of localised malignant melanoma. This treatment approach was well tolerated with mild myelosuppression and moderate limb toxicity. However, a significant improvement has been noted in the affected limb. This case demonstrated the successful use of isolated limb infusion with Melphalan in the management of localised cutaneous T-cell lymphoma. However, this result needs to be confirmed and further study is recommended. We are unaware there have been similar cases reported in the literature. [source]

    Isolated limb infusion: A review

    JOURNAL OF SURGICAL ONCOLOGY, Issue 2 2009
    Hidde M. Kroon MD
    Abstract Isolated limb perfusion is the preferred treatment option for locally advanced melanoma and sarcoma confined to a limb. This treatment results in high response rates with a satisfying duration of response in both tumours. A drawback of isolated limb perfusion, however, is the invasive and complex character of the procedure. Isolated limb infusion has been designed as a minimally invasive alternative to isolated limb perfusion. Treatment results of this simple technique, reported by various centres worldwide, show comparable response rates for melanoma and sarcoma. Therefore isolated limb infusion may replace isolated limb perfusion in the future as the preferred treatment option for these locally advanced limb tumours. J. Surg. Oncol. 2009;100:169,177. © 2009 Wiley-Liss, Inc. [source]