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Ligand Types (ligand + type)

Distribution by Scientific Domains

Chemistry	66%

Selected Abstracts

Trace metal distribution in soluble organic matter from municipal solid waste compost determined by size-exclusion chromatography

ENVIRONMENTAL TOXICOLOGY & CHEMISTRY, Issue 9 2002
Arno Kaschl
Abstract Municipal solid waste (MSW) composts carry high amounts of trace metals and organic complexing agents that may influence metal bioavailability and mobility after application to soils. In order to assess the degree of organic complexation of trace metals in the solution phase of MSW compost and the relevance of organic ligand type, size exclusion chromatography (SEC) was applied to compost-extracted organic ligands. Adjustment of the elution conditions minimized the interaction with the gel matrix for compost humic substances and dissolved organic matter (DOM) fractions. The SEC was then used to separate the aqueous compost extract into samples with distinct differences in chemical constituents. The highest quantities of Cu, Zn, Ni, Mn, and Cd were found to coelute with the main peak of the SEC elution curve, which, as observed by Fourier-transformed infrared (FTIR) spectroscopy, also had the highest density of carboxyl groups. The ratio of aromatic to aliphatic structures was higher for eluates with low retention times, and cations such as Al, Cr, and Fe were preferably associated with these larger organic molecules. All trace metals in the compost solution phase were bound mostly to DOM rather than forming inorganic complexes. [source]

Symmetric Versus Unsymmetric Platinum(II) Bis(aryleneethynylene)s with Distinct Electronic Structures for Optical Power Limiting/Optical Transparency Trade-off Optimization

ADVANCED FUNCTIONAL MATERIALS, Issue 4 2009
Guijiang Zhou
Abstract A new series of symmetric and unsymmetric Pt(II) bis(acetylide) complexes of the type DC,CPt(PBu3)2C,CD (DPtD), AC,CPt(PBu3)2C,CA (APtA) and DC,CPt(PBu3)2C,CA (DPtA) (D, donor groups; A, acceptor groups) are synthesized, and show superior optical power limiting (OPL)/optical transparency trade-offs. By tailoring the electronic properties of the aryleneethynylene group, distinct electronic structures for these metalated complexes can be obtained, which significantly affect their photophysical behavior and OPL properties for a nanosecond laser pulse at 532,nm. Electronic influence of the ligand type and the molecular symmetry of metal group on the optical transparency/nonlinearity optimization is thoroughly elucidated. Generally, aryleneethynylene ligands with , electron-accepting nature will effectively enhance the harvesting efficiency of the triplet excited states. The ligand variation to the OPL strength of these Pt(II) compounds follows the order: DPtD,>,DPtA,>,APtA. These results could be attributed to the distinctive excited state character induced by their different electronic structures, on the basis of the data from both photophysical studies and theoretical calculations. All of the complexes show very good optical transparencies in the visible-light region and exhibit excellent OPL responses with very impressive figure of merit ,ex/,o values (up to 17), which remarkably outweigh those of state-of-the-art reverse saturable absorption dyes such as C60 and metallophthalocyanines with very poor transparencies. Their lower optical-limiting thresholds (0.05,J,cm,2 at 92% linear transmittance) compared with that of the best materials (ca. 0.07,J,cm,2 for InPc and PbPc dyes) currently in use will render these highly transparent materials promising candidates for practical OPL devices for the protection of human eyes and other delicate electro-optic sensors. [source]

A Study of Heavy Metal Complexation in Grape Juice

ELECTROANALYSIS, Issue 5-6 2005
Íñigo Salinas
Abstract Differential pulse anodic stripping voltammetry, DPASV, has been used to monitor the initial stages of grape juice fermentation, focusing on Zn interactions with natural occurring ligands. Langmuir and Scatchard linearization methods have been employed. A 1,:,1 ratio has been found by either method; from Langmuir data analysis only one ligand population was found, while Scatchard approach gave rise to the detection of two ligand types. Both data analysis procedures led to the same total ligand concentration. When catechin was used as model ligand, a 1,:,1 ratio was found for Zn and also for Cu. [source]

Platinum-based anticancer agents: Innovative design strategies and biological perspectives

MEDICINAL RESEARCH REVIEWS, Issue 5 2003
Yee-Ping Ho
Abstract The impact of cisplatin on cancer chemotherapy cannot be denied. Over the past 20 years, much effort has been dedicated to discover new platinum-based anticancer agents that are superior to cisplatin or its analogue, carboplatin. Most structural modifications are based on changing one or both of the ligand types coordinated to platinum. Altering the leaving group can influence tissue and intracellular distribution of the drug, whereas the carrier ligand usually determines the structure of adducts formed with DNA. DNA,Pt adducts produced by cisplatin and many of its classical analogues are almost identical, and would explain their similar patterns of tumor sensitivity and susceptibility to resistance. Recently some highly innovative design strategies have emerged, aimed at overcoming platinum resistance and/or to introduce novel mechanisms of antitumor action. Platinum compounds bearing the 1,2-diaminocyclohexane carrier ligand; and those of multinuclear Pt complexes giving rise to radically different DNA,Pt adducts, have resulted in novel anticancer agents capable of circumventing cisplatin resistance. Other strategies have focused on integrating biologically active ligands with platinum moieties intended to selectively localizing the anticancer properties. With the rapid advance in molecular biology, combined with innovation, it is possible new Pt-based anticancer agents will materialize in the near future. © 2003 Wiley Periodicals, Inc. Med Res Rev, 23, No. 5, 633,655, 2003 [source]

New insights into intracellular lipid binding proteins: The role of buried water

PROTEIN SCIENCE, Issue 10 2002
Christian Lücke
Abstract The crystal structures of most intracellular lipid binding proteins (LBPs) show between 5 and 20 internally bound water molecules, depending on the presence or the absence of ligand inside the protein cavity. The structural and functional significance of these waters has been discussed for several LBPs based on studies that used various biophysical techniques. The present work focuses on two very different LBPs, heart-type fatty acid binding protein (H-FABP) and ileal lipid binding protein (ILBP). Using high-resolution nuclear magnetic resonance spectroscopy, certain resonances belonging to side-chain protons that are located inside the water-filled lipid binding cavity were observed. In the case of H-FABP, the pH- and temperature-dependent behavior of selected side-chain resonances (Ser82 OgH and the imidazole ring protons of His93) indicated an unusually slow exchange with the solvent, implying that the intricate hydrogen-bonding network of amino-acid side-chains and water molecules in the protein interior is very rigid. In addition, holo H-FABP appeared to display a reversible self-aggregation at physiological pH. For ILBP, on the other hand, a more solvent-accessible protein cavity was deduced based on the pH titration behavior of its histidine residues. Comparison with data from other LBPs implies that the evolutionary specialization of LBPs for certain ligand types was not only because of mutations of residues directly involved in ligand binding but also to a refinement of the internal water scaffold. [source]

,-Glycine- O:O,-di-,-oxo-bis[(glycinato- N,O)oxomolybdenum(V)]

ACTA CRYSTALLOGRAPHICA SECTION C, Issue 7 2000
Guang Liu
In the title compound, [Mo2O4(C2H4NO2)2(C2H5NO2)], two Mo atoms sit in the same distorted pentagonal bipyramid coordination environment. There are four ligand types: oxo-O, ,2 -O, ,2 -glycine and chelate glycine. There is an Mo,Mo bond between the two Mo atoms [2.552,(1),Å]. All amino groups participate in hydrogen bonding with O atoms of other molecules, thus connecting the molecules into a three-dimensional structure. [source]