Home  About us  Contact
 

Levin Syndrome (levin + syndrome)

Distribution by Scientific Domains
Medical Sciences66%

Selected Abstracts

Detection of Jarcho,Levin syndrome at 12 weeks' gestation by nuchal translucency screening and three-dimensional ultrasound

PRENATAL DIAGNOSIS, Issue 5 2001
Andrew D. Hull
Abstract Jarcho,Levin syndrome (JLS) or spondylothoracic dysotosis causes early newborn death from respiratory insufficiency. Prenatal diagnosis is possible using fetal ultrasound, but requires a high level of suspicion and definitive diagnosis may be delayed well into the second trimester. We present a case in which a combination of three-dimensional ultrasound and measurement of nuchal translucency thickness allowed successful detection of recurrent JLS at 12 weeks' gestation. Copyright © 2001 John Wiley & Sons, Ltd. [source]

Persistent neuropsychological deficits in the Kleine,Levin syndrome

ACTA NEUROLOGICA SCANDINAVICA, Issue 4 2003
Leonardo F. Fontenelle
No abstract is available for this article. [source]

A case of Kleine,Levin syndrome examined with SPECT and neuropsychological testing

ACTA NEUROLOGICA SCANDINAVICA, Issue 4 2002
A.-M. Landtblom
A case of Kleine,Levin syndrome with typical periodic hypersomnia and bulemia was diagnosed. On examination with single photo emission tomography (SPECT) (CERETEC®) during a relapse period and 2 weeks later there was marked cortical hypoperfusion of the frontal and temporal lobes, especially on the left side as well as in the right parietal lobe. Neuropsychological testing performed 1 week after a relapse showed a reduction in encoding to memory function of verbal learning indicating neocortical damage of the left fronto-temporal region. A follow-up 2 months later after the patient had spontaneously recovered showed only a slight left fronto-temporal disturbance. CT and MRI of the brain were normal although the MRI showed a large and asymmetric mamillary body. Neuropsychological testing 6 years after recovery showed pronounced reduction in short-time verbal and visual memory. Seven years after recovery SPECT demonstrated a normalized frontal perfusion but still a slight hypoperfusion in the left temporal lobe. Our results correlate to autopsy findings in two cases described previously. [source]

Diagnostic pitfalls in children with sleep disorders: two cases with hypersomnia

ACTA PAEDIATRICA, Issue 12 2008
Kutluhan Yilmaz
Abstract Sleep disorders are common in children, yet several clinical pitfalls give rise to the unrecognition or improper management of those children. Here, we present diagnostic difficulties in two adolescents with narcolepsy and Kleine,Levin syndrome. The first patient was a 12-year-old girl who had been given Na-valproate for nearly a year because hypersomnia was initially perceived as unconsciousness periods of epileptic spells, and later attributed to the antiepileptic drug. The other patient was a 14-year-old boy who had been managed as a specific psychiatric disorder for several months despite the characteristic symptoms of Kleine,Levin syndrome (hypersomnia, hyperphagia, hypersexuality, behavioural and cognitive dysfunction). Both cases emphasize that sleep disorders could be manifested with various clinics and that there are several diagnostic challenges in children. Conclusion: Sleep medicine needs to be given larger role in both training curriculum and post-graduate education for paediatricians. [source]