Latent Tuberculosis Infection (latent + tuberculosis_infection)

Distribution by Scientific Domains


Selected Abstracts


Latent Tuberculosis Infection in Travelers: Is There a Role for Screening Using Interferon-Gamma Release Assays?

JOURNAL OF TRAVEL MEDICINE, Issue 5 2009
DTM&H, Paul R. Ingram MBBS
First page of article [source]


Saying "no" to professional recommendations: Client values, beliefs, and evidence-based practice

JOURNAL OF THE AMERICAN ACADEMY OF NURSE PRACTITIONERS, Issue 12 2008
Cathy Michaels PhD, FAAN (Clinical Associate Professor)
Abstract Purpose: The purpose of this article is to explore the phenomenon of saying "no" to secondary prevention recommended by healthcare providers. Data sources: Extracted findings from two qualitative studies in which participants have said "no" to provider recommendations for secondary prevention, specifically screening mammograms or treatment for latent tuberculosis infection, are discussed. Conclusions: Although these two studies focus on different aspects of secondary prevention, both studies emphasize how client values and beliefs impact health decisions. In evidence-based practice (EBP), both scientific evidence and client values and beliefs must be considered. Nurse practitioners (NPs) have the skill set and are in a position to assist clients to mediate between their values and beliefs and current scientific evidence. Implications for practice: Several findings from the two qualitative studies are relevant for practice: qualitative studies provide information about values and beliefs for EBP, and findings from these particular qualitative studies demonstrated that women were protective about their health even though their values and beliefs did not align with current scientific evidence. Through client narratives, NPs can facilitate clients aligning personal values and beliefs with current scientific evidence in relationship to caring for self. [source]


Job-related risk of latent tuberculosis infection in a homogeneous population of hospital workers in a low incidence area,

AMERICAN JOURNAL OF INDUSTRIAL MEDICINE, Issue 4 2009
Alberto Franchi MD
Abstract Background Few comprehensive tuberculin surveys were carried out in a homogeneous population of health care workers (HCWs) in a low incidence area to assess the risk of tuberculosis (TB) infection by different occupational groups and units. Methods Community and occupational factors and tuberculin skin test (TST) reactivity were determined in 1,755 HCWs. Results The overall prevalence of tuberculin reactivity was 6%. Predicting factors for TST reactivity were age >47 years (OR,=,2.88), history of household TB contact (OR,=,2.41), years of work as HCW (OR,=,2.57), physician (OR,=,1.88), and working in microbiology (OR,=,4.94), dialysis/nephrology (OR,=,2.00), gynecology/obstetrics (OR,=,2.01). In a multiple regression model working in microbiology [OR,=,4.16 (1.27,13.6)], dialysis/nephrology [OR,=,2.52 (1.36,4.65)], gynecology/obstetrics [OR,=,2.46 (1.24,4.86)] and age >47 years [OR,=,1.98 (1.14,3.46)] were significant predictors for infection. Conclusions A higher risk of latent infection can be demonstrated in well-defined groups of HCWs. Am. J. Ind. Med. 52:297,303, 2009. © 2009 Wiley-Liss, Inc. [source]


Feasibility of commercial interferon-,-based methods for the diagnosis of latent Mycobacterium tuberculosis infection in Finland, a country of low incidence and high bacille Calmette,Guérin vaccination coverage

CLINICAL MICROBIOLOGY AND INFECTION, Issue 8 2007
T. Tuuminen
Abstract The performances of the QuantiFERON-TB Gold in Tubes (QFGT), T SPOT-TB (ELISPOT) and the Mantoux test were compared for the diagnosis of latent tuberculosis infection in Finland, a country of low tuberculosis incidence. In Cohort A (16 students), freshly isolated peripheral blood mononuclear cells (PBMCs), and in Cohort B (21 school children), cryopreserved PBMCs, were used for the ELISPOT assay. Cryopreservation of cells in fetal calf serum, but not in serum-free medium, produced false-positive results. Discrepancies between the results of the assays were observed. It was concluded that the accuracy of these ex-vivo methods needs additional evaluation. [source]