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Last Third (last + third)
Selected AbstractsMechanisms of intercellular hypertonicity and isotonic fluid absorption in proximal tubules of mammalian kidneysACTA PHYSIOLOGICA, Issue 1 2002F. KIILArticle first published online: 30 APR 200 ABSTRACT The main purpose of this theoretical analysis (second of two articles) is to examine whether transjunctional diffusion of NaCl causes intercellular hypertonicity, which permits transcellular water transport across solute-impermeable lateral cell membranes until osmotic equilibration. In the S2 segment with tubular NaCl concentration 140 mM, the calculated apical intercellular NaCl concentration is c0 , 132 mM, which exceeds peritubular NaCl concentration by 12 mM or 22 mOsm kg,1. Variations in volume flow, junctional reflection coefficient (,NaCl=0.25,0.50), gap distance (g=6,8 Å), junctional depth (d=18,100 Å), intercellular diffusion coefficient (DLIS=500,1500 ,m2 s,1) and hypothetical active NaCl transport alter c0 only by a fraction of 1 mM. However, dilution and back-leakage of NaHCO3 lower apical intercellular hyperosmolality to ,18 mOsm kg,1. Water transport through solute-impermeable lateral cell membranes continues until intercellular and cellular osmolalities are equal. Transcellular and transjunctional volume flow are of similar magnitude (2 nL min,1 mm,1 tubule length) in the S2 segment. Thus, diffusion ensures isotonic absorption of NaCl. Two-thirds of NaHCO3 and other actively transported sodium salts are extruded into the last third of the exponentially widening intercellular space where the exposure time is only 0.9 s. Osmotic equilibration is dependent on aquaporins in the cell membranes. If permeability to water is low, transcellular water transport stops; tubular fluid becomes hypotonic; NaCl diffusion diminishes, but transjunctional water transport remains unaltered as long as transcellular transport of NaHCO3 and other solutes provides the osmotic force. [source] Fetal cyclic motor activity in diabetic pregnancies: Sensitivity to maternal blood glucoseDEVELOPMENTAL PSYCHOBIOLOGY, Issue 1 2003Steven S. Robertson Abstract Spontaneous fetal movement in the last third of human gestation is dominated by irregular oscillations on a scale of minutes (cyclic motility, CM). The core properties of these oscillations are stable during the third trimester of gestation in normal fetuses, but disrupted by poorly controlled maternal diabetes. Here we investigated whether fetal CM is linked to short-term instabilities in maternal glucose metabolism. The fetuses of 40 mothers with type I (n,=,28) or gestational (n,=,12) diabetes were studied one to six times between 27 and 40 postmenstrual weeks of gestation. Fetal movement and maternal blood glucose concentration were measured during two separate periods of fetal activity in each session. Fetal CM was quantified with spectral analysis. Early in the third trimester, changes in the rate of oscillation in fetal CM between the two periods of activity were inversely related to changes in maternal blood glucose levels. Fetal CM was unrelated to concurrent maternal blood glucose levels at any point in the third trimester. The pattern of results suggests that disruption of the temporal organization of spontaneous fetal motor activity in pregnancies complicated by maternal diabetes represents an acute response to fluctuations in the metabolic environment rather than an alteration of CM development. © 2003 Wiley Periodicals, Inc. Dev Psychobiol 42: 9,16, 2003. [source] Teaching & Learning Guide for: The Origins of the Civil WarHISTORY COMPASS (ELECTRONIC), Issue 4 2007Nicole Etcheson Author's Introduction The author argues that slavery is the root cause of the Civil War even though historians have often posited other explanations. Some other interpretations have been ideological (i.e., about the morality of slavery), others have been economic, political, or cultural. Focus Questions 1If you were to make an argument for the causes of the Civil War, what evidence or types of evidence would you want to examine? 2In what ways can the different types of arguments (ideological, economic, political, and cultural), be combined to explain the causes of the Civil War? Do such arguments exclude or reinforce each other? In what ways? Author Recommends * E. L. Ayres, In the Presence of Mine Enemies: War in the Heart of America, 1859,1863 (New York, NY: Norton, 2003). A study of two counties, one north and one south, during the end of the sectional crisis and the early Civil War. While Potter, Walther, and Wilentz offer sweeping, often political, histories, Ayres offers a microhistory approach to the sectional conflict. Although Ayres writes within the tradition of seeing cultural differences between North and South, he concludes that slavery was the issue that drove the two sections apart. * M. A. Morrison, Slavery and the American West: The Eclipse of Manifest Destiny and the Coming of the Civil War (Chapel Hill, NC: University of North Carolina Press, 1997). Views the development of the sectional crisis through the lens of Manifest Destiny. Territorial expansion drove hostility between the sections. Morrison concentrates on the political developments of the period connected to the acquisition and organization of the territories to show how the issue of slavery in the territories polarized the sections. * D. M. Potter, The Impending Crisis, 1848,1861 (New York, NY: Harper & Row, 1976). The most comprehensive survey of the decade before the war. Potter traces the development of slavery as a political issue that North and South could not resolve. While it is a masterly and nuanced treatment of the political history, it does not incorporate social history and is more detailed than is useful for most undergraduates. E. H. Walther, The Shattering of the Union: America in the 1850s (Wilmington, Scholarly Resources, 2004) has recently supplanted Potter as a survey of the decade. It is an easier read for undergraduates and incorporates the new literature than has emerged since Potter wrote. * S. Wilentz, The Rise of American Democracy: Jefferson to Lincoln (New York, NY: Norton, 2005). A sweeping history of the United States from the constitutional era to the outbreak of the Civil War. Wilentz attempts to update Arthur M. Schlesinger Jr.'s synthesis The Age of Jackson by returning to a focus on the evolution of democracy while at the same time incorporating the social history that emerged after Schlesinger wrote. Only the last third of this very long book covers the 1850s, but Wilentz argues that democracy had taken differing sectional forms by that period: a free-labor version in the North and a plantation version in the South. Online Materials 1. The Valley of the Shadow: Two Communities in the American Civil War (http://valley.vcdh.virginia.edu/) A prize-winning website that profiles Augusta County, Virginia and Franklin County, Pennsylvania. Material from this website formed the basis of Ayres, In the Presence of Mine Enemies. Although the website primarily concentrates on the Civil War itself, it provides access to newspapers and letters and diaries from the 1850s that show the development of, and reaction to, the sectional crisis in those counties. It also shows students the types of materials (census, tax, and church records as well as newspapers and letters and diaries) with which historians work to build an argument. 2. American Memory from the Library of Congress (http://memory.loc.gov/ammem/index.html) Although not specifically devoted to the origins of the Civil War, the American Memory site provides access to the collections of the Library of Congress which contain massive amounts of primary materials for students and scholars. From the website, one can gain access to congressional documents, periodicals from the 1850s, nineteenth-century books, music, legal documents, memoirs by white and black southerners as well as slave narratives. Sample Syllabus Nicole Etcheson's ,Origins of the Civil War,' History Compass, 3/1 (2005), doi:10.1111/j.1478-0542.2005.00166.x can be used as a reading in any Civil War course. [source] The influence of climatic change and human activity on erosion processes in sub-arid watersheds in southern East SiberiaHYDROLOGICAL PROCESSES, Issue 16 2003Leonid M. Korytny Abstract A LUCIFS model variant is presented that represents the influence of climate and land use change on fluvial systems. The study considers trends of climatic characteristics (air temperature, annual precipitation totals, rainfall erosion index, aridity and continentality coefficients) for the steppe and partially wooded steppe watersheds of the south of East Siberia (the Yenisey River macro-watershed). It also describes the influence of these characteristics on erosion processes, one indicator of which is the suspended sediment yield. Changes in the river network structure (the order of rivers, lengths, etc.) as a result of agricultural activity during the 20th century are investigated by means of analysis of maps of different dates for one of the watersheds, that of the Selenga River, the biggest tributary of Lake Baikal. The study reveals an increase of erosion process intensity in the first two-thirds of the century in the Selenga River watershed and a reduction of this intensity in the last third of the century, both in the Selenga River watershed and in most of the other watersheds of the study area. Copyright © 2003 John Wiley & Sons, Ltd. [source] The world's first secular autonomous nursing school against the power of the churchesNURSING INQUIRY, Issue 2 2010Michel Nadot NADOT M. Nursing Inquiry 2010; 17: 118,127 The world's first secular autonomous nursing school against the power of the churches Secular healthcare practices were standardized well before the churches' established their influence over the nursing profession. Indeed, such practices, resting on the tripartite axiom of domus, familia, hominem, were already established in hospitals during the middle ages. It was not until the last third of the eighteenth century that the Catholic Church imposed its culture on secular health institutions; the Protestant church followed suit in 1836. In reaction to the encroachment of religious orders on civil society and the amalgam of religious denominations favored, for example, by the devout Florence Nightingale (supported, in 1854, by Sir Sidney Herbert, the influential Puseyite), it is on 20 July 1859 that the great Swiss nineteenth century pedagogue and recipient of the Académie française Gold Medal, Valérie de Gasparin-Boissier (1813,94), proposed a model of secular healthcare training for nurses that would become a counter-model set in opposition to religious health institutions. Forerunner of later schools, the world's first secular autonomous Nursing School was founded in Lausanne, Switzerland. Its mission was to bring decisive changes to the statutes of nurses' training, which were then still based on six principles not far removed from those of religious communities at the time: commitment for life, the Rule of St Augustine, obedience, celibacy, the renouncement of salary, and the uniform. [source] Light and Scanning Electron Microscopic Study on the Blood Vascular System of the Donkey PlacentaANATOMIA, HISTOLOGIA, EMBRYOLOGIA, Issue 2 2008A. Saber Summary The donkey placenta is diffuse and epitheliochorial with numerous microplacentomes consisting of a fetal microcotyledonary and a maternal microcaruncular part. The microplacentomal vasculature during the last third of pregnancy has been investigated by light microscopy in comparison to scanning electron microscopy of the materno-fetal contact surface and corrosion casts of blood vessels after plastic instillation from either the microcotyledonary or the microcaruncular side, and, for the first time in a perissodactyle, from both sides. Morphological data were semiquantitatively evaluated. The supplying parts of both, the microcotyledonary and the microcaruncular vascular system are strictly proximo-distally oriented, thus reaching the capillary systems or working parts in the shortest way possible. The straight course of the vasculature, particularly on the fetal side, suggests the occurrence of venulo-arteriolar back diffusion. The fetal capillary system consists of convolutes confronting the maternal septal capillary complexes in a countercurrent way. This materno-fetal blood flow interrelationship is highly efficient in terms of placental exchange, which is further supported (1) by dilations and increasing coiling of the fetal venular capillary limbs in particular and (2) by a decrease in the interhaemal distance from 12.5 to 7.2 ,m between the two capillary systems. Besides the countercurrent blood flow interrelationship, some maternal branch arterioles reach the septal capillary system from the maternally oriented pole of the microplacentome or microcaruncle, respectively, resulting in the less efficient crosscurrent blood flow. Hence, in the donkey placenta fetal and maternal blood vessels meet in a mix of countercurrent and crosscurrent flow patterns. [source] From Dream story (Schnitzler) to Eyes wide shut (Kubrick) From identity through meaning formation to identity through excitation,THE INTERNATIONAL JOURNAL OF PSYCHOANALYSIS, Issue 3 2007Joachim F. Danckwardt Using different psychoanalytic points of view, in this comparative study of Traumnovelle by Schnitzler and Eyes wide shut by Kubrick the author analyses the cultural changes between the first and last thirds of the 20th century. This change consists in the way ,facts of life' are dealt with. It is a change from identity through insight and understanding to an identity through excited self-objectification. This change proceeds along the lines of ,I think therefore I am' to ,I feel therefore I am' arriving at ,I am excited, therefore I am noticed and thus I am'. In the description and illustration of 48 hours in the life of a married couple, this transformation from thinking to feeling and sensing is made tangible. After 9 years of being married, the couple faces the end of their passionate love. They struggle with the primordial anxiety in love life: the traumatic loss of faith in one's capacity to love. This transformation is accompanied by a change in media that symbolizes the couple's experience: from the language of dreaming, reading and listening in Schnitzler to the representation in audiovisual media, i.e. visual art, theatre, movies and public events in Kubrick. It marks a change in the representation of psychic life in space and time. [source] | |||||||||||||