Large Thrombus (large + thrombus)

Distribution by Scientific Domains


Selected Abstracts


Possible Paradoxical Embolism as a Rare Cause for an Acute Myocardial Infarction

ECHOCARDIOGRAPHY, Issue 5 2006
Aleksandr Rovner M.D.
Paradoxical embolus is a rare entity and it has been incriminated as a cause of both cryptogenic strokes and myocardial infarctions (MI). Herein, we present a case of a patient diagnosed with a pulmonary embolism 1 week prior who now presented with an acute MI. Subsequent evaluation revealed a patent foramen ovale and a large thrombus in the right pulmonary artery. It was presumed that the etiology of her infarct was due to paradoxical embolus. The management of the patient is discussed and the literature is reviewed. [source]


Congenital Aneurysm of Left Atrial Appendage: A Case Report

JOURNAL OF CARDIAC SURGERY, Issue 1 2010
Sanjeev Gupta M.S.
We report a case of a two-year-old child with congenital aneurysm of the LAA with a large thrombus in it. He presented with an episode of seizures with left-sided hemiparesis. Diagnosis was based on transthoracic echocardiography and magnetic resonance imaging. The patient was successfully treated by surgical resection of the aneurysm and removal of the thrombus.(J Card Surg 2010;25:37-40) [source]


Angiographic Quantification of Thrombus in ST-Elevation Acute Myocardial Infarction Presenting with an Occluded Infarct-Related Artery and Its Relationship with Results of Percutaneous Intervention

JOURNAL OF INTERVENTIONAL CARDIOLOGY, Issue 3 2009
FAUSTINO MIRANDA-GUARDIOLA M.D.
Introduction: Routine thrombectomy has been advocated for ST-segment-elevation myocardial infarction (STEMI), but it is unknown how many patients present with a large thrombus. We aimed to quantify the intracoronary thrombus in STEMI and to correlate it with procedure results. Methods: In 98 patients with STEMI and TIMI flow grades 0,2 in the infarct-related artery, thrombus was qualified as small (ST) when its maximal dimension was <2 vessel diameters and large (LT) when ,2. Main outcome measures were TIMI flow, myocardial blush grade (MBG), corrected TIMI frame count (cTFC), and ST-segment elevation resolution (STSER). Results: Only a third of the patients presented with an LT. Thrombus grade was independent of the initial vessel patency. Diabetes (OR 3.1, 95% CI 1.20,8.02, P = 0.027) and pretreatment with clopidogrel (OR 0.27, 95% CI 0.08,0.86, P = 0.034) were independent predictors of LT. LT was an independent predictor of unfavorable results: <3 TIMI flow (OR 2.87, 95% CI 1.04,8.00, P = 0.043), MBG 0,1 (OR 3.36, 95% CI 1.10,10.26, P = 0.033), cTFC > 21 (OR 2.86, 95% CI 1.09,7.49, P = 0.033) and <50% STSER (OR 3.19, 95% CI 1.06,9.63, P = 0.039). Conclusion: Only a third of STEMI patients present with an LT, being diabetes and lack of clopidogrel pretreatment independent predictors. An LT is strongly associated with worse PCI results. [source]


rFV11a and paediatric open-heart surgery: thrombosis in the cardiopulmonary bypass circuit in spite of adequate markers of anticoagulation

ANAESTHESIA, Issue 6 2009
N. A. Chambers
Summary Recombinant activated factor V11 (rFV11a) is a relatively new procoagulant agent and its place in surgical practice continues to be investigated. We report the use of rFV11a to help manage bleeding in the operating theatre in a neonate, following weaning from cardiopulmonary bypass for arterial switch procedure, when bleeding continued in spite of maximal medical therapy and apparent exclusion of a surgical cause of bleeding. In this patient administration of rFV11a failed to facilitate haemostasis and cardiopulmonary bypass was re-instituted allowing location and repair of a small awkward surgical source. Separation from this additional 20 min of bypass was successful but a large thrombus was noted in the membrane oxygenator of the extracorporeal circuit in spite of the presence of adequate ,laboratory' markers of anticoagulation in the pump blood. No adverse sequelae to the patient occurred. [source]