Laboratory Facility (laboratory + facility)

Distribution by Scientific Domains


Selected Abstracts


Sea louse control in Scotland, past and present,

PEST MANAGEMENT SCIENCE (FORMERLY: PESTICIDE SCIENCE), Issue 6 2002
Gordon H Rae
Abstract Methods for farming the Atlantic salmon (Salmo salar L) in Scotland were developed at the Unilever Research Laboratory facility at Lochailort on the west coast of Scotland in the late 1960s. By the spring of 1972 a fledgling commercial company had been set up and Marine Harvest, as it was known, received its first year class of smolts at Lochailort. Sea lice (Lepeophtheirus salmonis Krøyer) from passing wild fish infected the smolts but did not cause any significant damage until the summer of 1976 when intervention was required. The Scottish industry has since grown to become a vital source of employment for fragile rural economies and produced about 130,000 tonnes of salmon in 2000. This paper gives an overview of how fish welfare has been maintained by the development of treatments and management strategies aimed at minimising the impact of sea lice. © 2002 Society of Chemical Industry [source]


`Segmented' crystals solved using synchrotron radiation: (2S,3R,4S,5R)-4-(10,10-dimethyl-3,3-dioxo-3,6 -thia-4-azatricyclo[5.2.1.01,5]decan-4-ylcarbonyl)-2,6-diphenylperhydropyrrolo[3,4- c]pyrrole-1,3-dione

ACTA CRYSTALLOGRAPHICA SECTION C, Issue 7 2009
Graeme J. Gainsford
The title compound, C29H31N3O5S, forms needle-shaped `segmented' crystals, thereby inhibiting successful single-crystal data collection using conventional laboratory facilities. One crystallite of dimensions 0.15 × 0.03 × 0.01,mm yielded sufficent single-crystal diffraction data on the Australian Synchrotron PX1 beamline. The two independent molecules in the asymmetric unit are nearly superimposable and show only minor conformational deviations from closely related compounds. The molecules pack using one N,H...O hydrogen bond and several phenyl C,H...O(=S), phenyl C,H...O(=C) and methylene C,H...O(=C) hydrogen bonds and weak C,H..., interactions. [source]


Performance of the Panleucogating protocol for CD4+ T cell enumeration in an HIV dedicated laboratory facility in Barbados,,

CYTOMETRY, Issue S1 2008
Namrata Sippy-Chatrani
Abstract Objective: To compare the Panleucogating (PLG) protocol with the routinely used four-color protocol for CD4+ T cell count enumeration. Design and Methods: One hundred fifty-three blood samples were randomly selected from samples received at the National HIV Laboratory for routine immunological monitoring. Samples were prepared using Coulter CYTO-STAT® tetraCHROME monoclonal antibodies and FlowCAREÔ PLG CD4 reagent for four-color and PLG, respectively, and analyzed on the Beckman Coulter EPICS XL flow cytometer. The PLG protocol used a sequential gating strategy where CD4+ T cells were identified using side scatter properties of cells and CD45 staining. The four-color protocol used CD45 and CD3 to identify CD4+ T cells. Results: Absolute CD4+ T cell counts and percentages ranged from 4 to 1,285 cells/,L and 0.9 to 46.7%, respectively. Linear regression analyses revealed good correlation of PLG with the four-color protocol (absolute counts, R2 = 0.95; percentages, R2 = 0.98) over the entire range including the clinically relevant range. Bland Altman statistics revealed no bias for CD4 counts <500 cells/,L and a slight underestimation by PLG for counts >500 cells/,L (Bias = ,32.7 cells/,L; 95% agreement limits = ,151.3, +86.0). CD4+ T cell percentages were the similar over the entire range (Bias = 0.6%; 95% agreement limits = ,1.97 ± 3.18). Conclusions: PLG is an accurate method for enumerating CD4+ T cells and has resulted in major cost savings to the Government of Barbados. This has implications for the sustainability of the National HIV containment program in Barbados and the other resource limited Caribbean countries. The PLG technique is now being routinely used in Barbados. © 2008 Clinical Cytometry Society [source]


Physical properties of meteorites,Applications in space missions to asteroids

METEORITICS & PLANETARY SCIENCE, Issue 6 2008
T. KOHOUT
However, more detailed observations indicate that differences exist in composition between asteroids and meteorites resulting in difficulties when searching for meteorite-asteroid match. We show that among other physical parameters the magnetic susceptibility of an asteroid can be determined remotely from the magnetic induction by solar wind using an orbiting spacecraft or directly using the AC coil on the lander, or it can be measured in samples returned to the laboratory. The shape corrected value of the true magnetic susceptibility of an asteroid can be compared to those of meteorites in the existing database, allowing closer match between asteroids and meteorites. The database of physical properties contains over 700 samples and was recently enlarged with measurements of meteorites in European museums using mobile laboratory facility. [source]