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Laser Heating (laser + heating)
Selected AbstractsUltrasound guidance and monitoring of laser-based fat removalLASERS IN SURGERY AND MEDICINE, Issue 10 2008Jignesh Shah MS Abstract Background and Objectives We report on a study to investigate feasibility of utilizing ultrasound imaging to guide laser removal of subcutaneous fat. Ultrasound imaging can be used to identify the tissue composition and to monitor the temperature increase in response to laser irradiation. Study Design/Materials and Methods Laser heating was performed on ex vivo porcine subcutaneous fat through the overlying skin using a continuous wave laser operating at 1,210 nm optical wavelength. Ultrasound images were recorded using a 10 MHz linear array-based ultrasound imaging system. Results Ultrasound imaging was utilized to differentiate between water-based and lipid-based regions within the porcine tissue and to identify the dermis-fat junction. Temperature maps during the laser exposure in the skin and fatty tissue layers were computed. Conclusions Results of our study demonstrate the potential of using ultrasound imaging to guide laser fat removal. Lasers Surg. Med. 40:680,687, 2008. © 2008 Wiley-Liss, Inc. [source] The structure and mechanical properties of amorphous and nanocrystalline Fe,Si,B alloysJOURNAL OF MICROSCOPY, Issue 1 2006A. SYPIE Summary This article describes the results of investigations of the microstructure of failure surfaces and the mechanism of deformation of an amorphous Fe80Si11B9 alloy, nanocrystallized with the use of Nd:YAG pulsed laser heating. The research included ,in situ' tensile testing in a scanning electron microscope. Mechanical properties were also measured on an Instron-type machine for the amorphous and nanocrystalline alloys. The mechanical tensile tests performed on the amorphous and nanocrystalline samples showed a ductile fracture surface with very high fracture stress. Detailed observations of the flow deformation and fractures revealed the relationship between the quenched-in crystalline and mechanical behaviour. [source] Structural Changes in Silica Glass by Continuous-Wave Laser Backside IrradiationJOURNAL OF THE AMERICAN CERAMIC SOCIETY, Issue 6 2010Hirofumi Hidai We report on a permanent change in the physical properties inside silica glass by rapid heating and quenching using a continuous-wave laser beam. The absorption of the glass was enhanced by laser heating, and the heated spot moved as a result of thermal radiation and conduction. To trigger heating, an absorbent material was placed on the backside of a glass plate and irradiated through the glass. Laser illumination with a power of 11 W focused on the absorbent material induced a cylindrical modified zone along the laser beam with a length of up to 5.5 mm that was modified at a rate of ,130 mm/s. The characteristics of the modified silica glass were studied. The modified area consists of two layers, and the diameters of the inner and outer zones are ,40 and ,55 ,m, respectively. The inner zone was modified by laser heating. The fictive temperature is estimated to be ,1900 K. The etch rate and hardness of the modified glass increased owing to the increment of the fictive temperature. The outer zone was modified by tensile stress due to the densification of the inner zone. In the outer zone, the etch rate is increased and hardness is decreased. [source] Energetics of Defect Fluorite and Pyrochlore Phases in Lanthanum and Gadolinium HafnatesJOURNAL OF THE AMERICAN CERAMIC SOCIETY, Issue 4 2007Sergey V. Ushakov Aerodynamic levitation combined with laser heating was used to prepare melts in the HfO2,La2O3 (,Gd2O3) systems. All melts crystallized upon quenching in oxygen. Hf2La2O7 pyrochlore and Gd0.5Hf0.5O1.75 fluorite phases were identified. Gd0.5Hf0.5O1.75 fluorite was transformed into the pyrochlore structure by annealing at 1450°C. Pyrochlore that crystallized from HfO2 - La2O3 melts contained 31.6,34.2 mol% La2O3. The unit cell parameter increased linearly with La content from 10.736 to 10.789 Å. Drop solution calorimetric experiments were performed in 3Na2O·4MoO3 melt at 702°C. The enthalpies of formation from the oxides for pyrochlore phases are ,107.0±5.0 kJ/mol for Hf2La2O7 and ,48.8±4.7 kJ/mol for Hf2Gd2O7. The enthalpy of the pyrochlore,fluorite phase transition in Hf2Gd2O7 is 23.6±3.1 kJ/mol. [source] Quantitative assessment of chondrocyte viability after laser mediated reshaping: A novel application of flow cytometryLASERS IN SURGERY AND MEDICINE, Issue 1 2003Alexandre Rasouli BS Abstract Background and Objectives Lasers can be used to reshape cartilage by accelerating mechanical stress relaxation. In this study, fluorescent differential cell viability staining and flow cytometry were used to determine chondrocyte viability following laser heating. Study Design/Materials and Methods Porcine septal cartilages were irradiated with an Nd:YAG laser (,,= 1.32 ,m, 25 W/cm2) while surface temperature, stress relaxation, and diffuse reflectance were recorded. Each slab received one, two, or three laser exposures (respective exposure times of 6.7, 7.2, 10 seconds). Irradiated samples were then divided into two groups analyzed immediately and at 5 days following laser exposure. Chondrocytes were isolated following serial enzymatic digestion, and stained using SYTO®/DEAD RedÔ (Molecular Probes, Eugene, OR). A flow cytometer was then used to detect differential cell fluorescence; size; granularity; and the number of live cells, dead cells, and post-irradiation debris in each treatment population. Results Nearly 60% of chondrocytes from reshaped cartilage samples isolated shortly after one irradiation, were viable while non-irradiated controls were 100% viable. Specimens irradiated two or three times demonstrated increasing amounts of cellular debris along with a reduction in chondrocyte viability: 31 and 16% after two and three exposures, respectively. In those samples maintained in culture medium and assayed 5 days after irradiation, viability was reduced by 28,88%, with the least amount of deterioration in untreated and singly irradiated samples. Conclusions Functional fluorescent dyes combined with flow cytometric analysis successfully determines the effect of laser irradiation on the viability of reshaped cartilage. Lasers Surg. Med. 32:3,9,2003. © 2003 Wiley-Liss, Inc. [source] Thermoelasticity with second sound,exponential stability in linear and non-linear 1-dMATHEMATICAL METHODS IN THE APPLIED SCIENCES, Issue 5 2002Reinhard Racke We consider linear and non-linear thermoelastic systems in one space dimension where thermal disturbances are modelled propagating as wave-like pulses travelling at finite speed. This removal of the physical paradox of infinite propagation speed in the classical theory of thermoelasticity within Fourier's law is achieved using Cattaneo's law for heat conduction. For different boundary conditions, in particular for those arising in pulsed laser heating of solids, the exponential stability of the now purely, but slightly damped, hyperbolic linear system is proved. A comparison with classical hyperbolic,parabolic thermoelasticity is given. For Dirichlet type boundary conditions,rigidly clamped, constant temperature,the global existence of small, smooth solutions and the exponential stability are proved for a non-linear system. Copyright © 2002 John Wiley & Sons, Ltd. [source] Micro-fabrication and monitoring of three-dimensional microstructures based on laser-induced thermoplastic formationMICROSCOPY RESEARCH AND TECHNIQUE, Issue 10 2009Leyan Wang Abstract This article reports a novel laser-induced micro-fabrication method and its monitoring system for three-dimensional (3D) microstructures. The mechanism of the method is that a small zone of thermoplastic material melted by laser heating grows in liquid surrounding environment, solidifying into a convex microstructure, such as micro-dot or micro-pillar. A laser diode (808 nm) with maximum power output of 130 mW is used as power source, and a kind of paraffin mixed with stearic acid and paint serves as the thermoplastic material for 3D microstructure formation experiments. A light microscope system consisting of a charge-coupled device (CCD) and a computer is utilized to realize real-time observation of the micro-fabricating process. The distribution of local temperature rise on material surface created by laser irradiation is simulated. The effects of liquid environment on microstructure formation have been theoretically analyzed and experimentally studied. Experiments are further carried out to investigate the relationship between laser spot and fabricated microstructures. The results indicate that the widths of micro-dots or micro-pillars are mostly determined by the size of focal spot, and their heights increase with the enlargement of laser power density. With this method, a micro-dot array of Chinese characters meaning "China" has been successfully fabricated through computer programming. This method has the advantages of implementing direct, mask-less, real-time and inexpensive 3D microstructure fabrication. Therefore, it would be widely applied in the fields of micro/nano-technology for practical fabrication of different kinds of 3D microstructures. Microsc. Res. Tech., 2009. © 2009 Wiley-Liss, Inc. [source] Determination of the Minimum Temperature Required for Selective Photothermal Destruction of Cancer Cells with the Use of Immunotargeted Gold NanoparticlesPHOTOCHEMISTRY & PHOTOBIOLOGY, Issue 2 2006Xiaohua Huang ABSTRACT Laser photothermal therapy of cancer with the use of gold nanoparticles immunotargeted to molecular markers on the cell surface has been shown to he an effective modality to selectively kill cancer cells at much lower laser powers than those needed for healthy cells. To elucidate the minimum light dosimetry required to induce cell death, photothermal destruction of two cancerous cell lines and a noncancerous cell line treated with antiepidermal growth factor receptor (anti-EGFR) antibody-conjugated gold nanoparticles is studied, and a numerical heat transport model is used to estimate the local temperature rise within the cells as a result of the laser heating of the gold nanoparticles. It is found that cell samples with higher nanoparticle loading require a lower incident laser power to achieve a certain temperature rise. Numerically estimated temperatures of 70,80°C achieved by heating the gold particles agree well with the measured threshold temperature for destruction of the cell lines by oven heating and those measured in an earlier nanoshell method. Specific binding of anti-EGFR antibody to cancerous cells overexpressing EGFR selectively increases the gold nanoparticle loading within cancerous cells, thus allowing the cancerous cells to be destroyed at lower laser power thresholds than needed for the noncancerous cells. in addition, photothermal therapy using gold nanoparticles requires lower laser power thresholds than therapies using conventional dyes due to the much higher absorption coefficient of the gold nanoparticles. [source] | ||||||||||