Another Cause (another + cause)

Distribution by Scientific Domains

Selected Abstracts

Another cause of bloody diarrhoea in infancy: Cytomegalovirus colitis in an immunocompetent child

R Hinds
Abstract: Although a ubiquitous pathogen, cytomegalovirus (CMV) is very rarely thought to be the cause of significant gastrointestinal infection in the immunocompetent child. We report the case of a 2-month-old infant who presented with bloody diarrhoea and severe dehydration, which was subsequently diagnosed as CMV enterocolitis and resolved spontaneously without antiviral treatment. [source]

Expansion of Elaeagnus umbellata on a gravel bar in the Naka River, Shikoku, Japan

Mari Kohri
Abstract The present study seeks to identify the expansion process of the shrub Elaeagnus umbellata Thunb. (Elaeagnaceae) on a gravel bar in the Naka River, Shikoku, Japan, in relation to the hydrogeomorphologic regime of the habitat. The establishment pattern was determined by a series of aerial photographs, and the establishment years were confirmed by examining tree rings taken from five different areas within the population. The topographic change of the river cross-section was analyzed and it was found that the establishment occurred exactly when and where the riverbed began to stabilize. The three cohorts of 15-, 10- and 4-year-olds were recognized, the younger individuals being downstream. The episodic age pattern was significantly synchronized with large floods occurring during the autumn fruit-ripening season. These spatial and temporal occurrence patterns indicated the probability of hydrochory, which ultimately enhanced the dissemination of endozoochorous E. umbellata seeds into the newly created habitat on the downstream part of the gravel bar. Another cause of quick dominance was its vigorous sprouting ability, which enabled the established E. umbellata to withstand damage and sediment burial by strong floods. The erosion of the deepest part of the riverbed increased the relative elevation of the vegetated stand, which ultimately decreased the frequency and magnitude of disturbance during flood inundation after the 1980s. Consequently the hydrogeomorphic regime of the floods played an important role in habitat creation, seed dispersal, and in the survival of the established individuals, and it determined the population formation and expansion of E. umbellata on the riparian gravel bar. [source]

Orthostatic Headaches in the Syndrome of the Trephined: Resolution Following Cranioplasty

HEADACHE, Issue 7 2010
Bahram Mokri MD
Objective., To draw attention to the syndrome of the trephined as a potential cause for orthostatic headaches without cerebrospinal fluid (CSF) leak. Background., Orthostatic headaches typically result from CSF leaks but sometimes may occur in conditions without any evidence of CSF leakage. Methods., A 37-year-old right-handed woman became comatose after a motor vehicle accident with cerebral contusions and massive left cerebral edema. A large frontoparietal craniectomy was carried out. In 5 months, she made good neurologic recovery. Freeze-preserved bone flap was placed back. In several weeks she was functionally near normal. Two years later, she began to complain of orthostatic headache and gradually additional manifestations appeared including progressive gait unsteadiness, imprecise speech, cognitive difficulties, and an increasing left hemiparesis along with progressive sinking of the skull defect and shift of the midline and ventricular distortion. She underwent removal of resorptive sinking bone flap and construction of an acrylic cranioplasty. Results., At 6-month follow-up, there was complete resolution of the orthostatic headaches, remarkable neurologic improvement along with resolution of midline shift and ventricular distortion. Conclusion., The syndrome of the trephined is yet another cause of orthostatic headaches without CSF leak. [source]

The c.43_44insCTG variation in PCSK9 is associated with low plasma LDL-cholesterol in a Caucasian population,,

HUMAN MUTATION, Issue 5 2006
Pin Yue
Abstract The genetic etiology of familial hypobetalipoproteinemia (FHBL) is unclear in the majority of cases. Mutations in apolipoprotein B (APOB) are the only confirmed causes of FHBL. Recently, loss-of-function mutations of PCSK9 gene have been shown to be associated with the hypocholesterolemia phenotype. Our primary goal was to confirm that mutations in PCSK9 could be another cause of FHBL. Using the sequencing approach, we found that the c.43_44insCTG variation in PCSK9, a common in-frame insertion in both African American and Caucasian populations, is associated with the hypocholesterolemia phenotype in three FHBL families. Then we tested whether this variation could be associated with lower cholesterol levels in the general population. A total of 403 subjects from a Caucasian population, in which hypobetalipoprotein (HBL) and normal groups were classified using standard criteria, were sequenced for this variation. The allele frequency of this variation in the HBL group was 0.186, but was only 0.128 in the normal lipid group. The mean plasma low-density lipoprotein (LDL)-cholesterol level in subjects heterozygous for this variant is significantly lower than that in the normal group (p<0.01). Heterozygous subjects also had higher high-density lipoprotein (HDL)-cholesterol levels (p<0.01). In general, LDL-cholesterol concentration in individuals with PCSK9 c.43_44insCTG variation was ,10,15 mg/dL lower than that in normal individuals. We conclude that the c.43_44insCTG variant plays a role in lowering cholesterol in the general population. Hum Mutat 27(5), 460,466, 2006. Published 2006 Wiley-Liss, Inc. [source]

Onycotrychia?: subungual hair follicle as another cause of longitudinal melanonychia or pigmentation,,,Hair follicle as cause of melanonychia

O Ferreira
No abstract is available for this article. [source]

Resolution of orofacial granulomatosis with amalgam removal

E Guttman-Yassky
ABSTRACT A 61-year-old woman presented with a 2-year history of an abnormal erythematous swelling on the upper lip and cheek. Upon examination there were no other physical findings. Histological examination found discreet sarcoidal granulomas in the lower dermis. Routine laboratory studies, chest radiographs and pulmonary functions were all normal. Clinical presentation and histological findings were, therefore, compatible with the diagnosis of orofacial granulomatosis (OFG). The patient was patch tested with an extended standard series that included metal,salt, dental prosthesis, bakery and corticosteroids series. The patch test was positive (score ++) after 48 and 72 h for mercury in the metal,salt and dental prosthesis series. During the past decade the patient had received amalgam fillings of several dental cavities, including one adjacent to the swollen cheek. The unilateral localization of the soft tissue swelling adjacent to the amalgam tooth fillings, along with the positive patch test for mercury, raised the possibility that the OFG was part of a delayed hypersensitive reaction to the fillings. The patient therefore underwent a total amalgam replacement procedure; complete disappearance of the swelling overlying the right cheek was observed within 7 weeks and the swelling of the upper lip subsided completely within 6 months. We propose that mercury in amalgam tooth fillings is another cause of OFG and suggest appropriate patch testing in patients who do not have an apparent cause of OFG. [source]

Familial Hypocalciuric Hypercalcemia in the Donor and Recipient of a Living Related Donor Kidney Transplant

J. E. Novak
Familial hypocalciuric hypercalcemia (FHH) is caused by heterozygous inactivation of the calcium-sensing receptor, which is notably expressed in parathyroid and kidney. FHH is characterized by asymptomatic hypercalcemia and hypophosphatemia and confers minimal, if any, morbidity. Renal transplantation in patients with FHH has not been described previously. This report describes a patient with FHH who developed end-stage renal disease from another cause and subsequently received a living related donor kidney transplant from her FHH-affected daughter. The excellent posttransplant clinical course of both recipient and donor is emphasized. [source]