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Kinds of It Terms modified by It Selected AbstractsDeterminants of information systems outsourcing in hotels from the resource-based view: an empirical studyINTERNATIONAL JOURNAL OF TOURISM RESEARCH, Issue 1 2005Tomás F. Espino-Rodríguez Abstract The objective of this study is to determine the factors affecting outsourcing of information system/information technology (IS/IT) activities in hotels from the resource-based view of the firm. The factors considered are the conditions that the systems area resources must meet for that area to have a competitive value. The reasons, which are both strategic and tactical, are discussed. The former are mainly related to quality, improvement of service and concentration on core activities, whereas the latter are tactical or cost-related reasons justifying the selection of the outsourcing strategy for this activity. The results indicate the factors determining IS/IT activity outsourcing are related to the creation of valuable resources and to market transaction costs, and the IS/IT area performance does not influence the decision to outsource. It is also shown that the reasons justifying outsourcing are strategic; related to the core competencies and quality of service and not to cost reduction. Copyright © 2005 John Wiley & Sons, Ltd. [source] Medical informatics: Market for IS/ITPROCEEDINGS OF THE AMERICAN SOCIETY FOR INFORMATION SCIENCE & TECHNOLOGY (ELECTRONIC), Issue 1 2002Theodore Allan Morris Following on the lead from earlier pilot studies, the present work uses co-occurrence analysis of INSPEC classification codes and thesaurus terms assigned to Medical Informatics journal articles and proceedings papers to reveal a more complete perspective of how information science and information technology authors view Medical Informatics. An important underlying dimension to this perspective portrays a continuum of interest from biophysics through biomechanics to biomedicine to (presumably) biology (which is noticeable in its absence). Medical Informatics may be described as the application of information science and information technology to the theoretical and practical problems of biomedical research, clinical practice, and medical education. However, study results suggest IS/IT considers its relationship to Medicine within Medical Informatics as that of supplier vs. market. [source] Irritant threshold and histological response of epidermis to irritant applicationCONTACT DERMATITIS, Issue 5-6 2004H. R. Smith Individuals vary in their ability to react to irritants, which can be demonstrated for sodium lauryl sulfate (SLS) using the irritant threshold (IT) test. We aimed to study whether the histological and immunohistochemical features of the skin following SLS exposure varied with subject's IT. 8 subjects were recruited. Their IT was measured. Biopsies were taken after 2 hr and 4 hr of occlusion with 20% SLS and control. The specimens were stained with haematoxylin and eosin and for Langerhans cells. At 4-hr, low-threshold subjects developed changes to a greater extent than high-threshold subjects. The relationship of histological reaction to IT could be related to a differential pro-inflammatory cytokine response in subjects. Low IT has been previously associated with a tumour necrosis factor alpha promoter region polymorphism. [source] Information Processing and Firm-Internal Environment Contingencies: Performance Impact on Global New Product DevelopmentCREATIVITY AND INNOVATION MANAGEMENT, Issue 3 2010Elko Kleinschmidt Innovation in its essence is an information processing activity. Thus, a major factor impacting the success of new product development (NPD) programs, especially those responding to global markets, is the firm's ability to access, share and apply NPD information, which is often widely dispersed, functionally, geographically and culturally. To this end, an IT-communication strength is essential, one that is nested in an internal organizational environment that ensures its effective functioning. Using organizational information processing (OIP) theory as a framework, superior global NPD program performance is shown to result from an effective IT/Communication strength and the commitment components of the firm's internal environment, which are hypothesized to moderate this relationship. IT/Communication strength is identified in this study in terms of two components including the IT/Comm Infrastructure and IT/Comm Capability of the firm, whereas the moderating internal environment of the firm incorporates Resource Commitment and Senior Management Involvement. Data from a major empirical study of international NPD programs (382 SBUs) are used to develop and test this model. Based on a hierarchical regression analysis, the results are substantially supportive, with some unexpected findings. These shed light on the complex relationships of the firm's internal environment, OIP competency, and global NPD program performance. [source] Impact of assertive community treatment and client characteristics on criminal justice outcomes in dual disorder homeless individualsCRIMINAL BEHAVIOUR AND MENTAL HEALTH, Issue 4 2005Dr Robert J. Calsyn PhD Background People with severe mental illness and substance use disorders (dual disorder) often have considerable contact with the criminal justice system. Aims To test the effects of client characteristics on six criminal justice outcomes among homeless (at intake) people with mental illness and substance misuse disorders. Methods The sample was of participants in a randomized controlled trial comparing standard treatment, assertive community treatment (ACT) and integrated treatment (IT). Data were analysed using hierarchical logistic regression. Results Half the sample was arrested and a quarter incarcerated during the two-year follow-up period. The regression models explained between 22% and 35% of the variance of the following criminal justice measures: (1) major offences, (2) minor offences, (3) substance-use-related offences, (4) incarcerations, (5) arrests, and (6) summons. Prior criminal behaviour was the strongest predictor of all of the dependent variables; in general, demographic and diagnostic variables were not. Similarly, neither the type nor the amount of mental health treatment received predicted subsequent criminal behaviour. Conclusion Elsewhere the authors have shown that ACT and IT had advantages for health and stability of accommodation but these analyses suggest that more specialized interventions are needed to reduce criminal behaviour in dual disorder individuals. Copyright © 2005 John Wiley & Sons, Ltd. [source] Management Speak in ITCRITICAL QUARTERLY, Issue 4 2002James Woudhuysen First page of article [source] Paper Versus Electronic Medical Records: The Effects of Access on Physicians' Decisions to Use Complex Information Technologies,DECISION SCIENCES, Issue 2 2009Virginia Ilie ABSTRACT This study examines physicians' responses to complex information technologies (IT) in the health care supply chain. We extend individual-level IT adoption models by incorporating a new construct: system accessibility. The main premise of the study is, when faced with a decision between alternate IT systems, individual users tend to select and make use of the technology or system that is most readily accessible. We discuss both physical and logical dimensions of accessibility as they relate to adoption of electronic medical records (EMR). Physical accessibility refers to the availability of computers that can be used to access EMR, while logical accessibility refers to the ease or difficulty of logging into the system. Using data from a survey of 199 physicians practicing in a large U.S. hospital, we show that, when deciding between the paper chart and EMR, accessibility is an important consideration in a physician's decision to use the system. Both dimensions of accessibility act as barriers to EMR use intentions through their indirect effect on physicians' perceptions of EMR usefulness and ease of use. Logical access also has a direct effect on EMR use intentions. We conclude that accessibility is an important factor that limits acceptance of complex IT such as EMR. [source] Examining the Antecedents and Consequences of CIO Strategic Decision-Making Authority: An Empirical Study,DECISION SCIENCES, Issue 4 2008David S. Preston ABSTRACT Despite the strategic importance of information technology (IT) to contemporary firms, chief information officers (CIO) often still have varying degrees of strategic decision-making authority. In this study, we apply the theory of managerial discretion to define CIO strategic decision-making authority and argue that the CIO's level of strategic decision-making authority directly influences IT's contribution to organization performance. We also draw on the power and politics perspective in the strategic decision-making literature to identify the direct antecedents to the CIO's strategic decision-making authority. A theoretical model is presented and empirically tested using survey data collected from a cross-industry sample of 174 matched pairs of CIOs and top business executives through structural equation modeling. The results suggest that organizational climate, organizational support for IT, the CIO's structural power, the CIO's level of strategic effectiveness, and a strong partnership between the CIO and top management team directly influence the CIO's level of strategic decision-making authority within the organization. The results also suggest that the CIO's strategic decision-making authority in the organization directly influences the contribution of IT to firm performance and that effective CIOs have a greater influence on IT's contribution when provided with strategic decision-making authority. [source] Endogenous Adaptation: The Effects of Technology Position and Planning Mode on IT-Enabled Change,DECISION SCIENCES, Issue 3 2006Victoria L. Mitchell ABSTRACT The redesign of information technology (IT)-enabled work processes often necessitates fundamental design changes to the intended work process, the IT platform hosting the work process, or both. Research suggests that such design changes often can be traced to earlier decisions involving endogenous adaptation or internal organizational change. Two such decisions are a firm's technology position and planning mode. This study examines the relationship between technology position and planning mode in predicting the magnitude of design change in process redesign projects. The conceptual frame applied in examining these relationships involves a synthesis of Miles and Snow's adaptive cycle with elements central to concurrent engineering. Our results indicate that the magnitude of design change is related to differences in technology position and planning mode. To effectively implement organizational change, firms must leverage their IT platform by carefully timing IT investments in accordance with their adopted technology position. Directing the trajectory of a firm's IT platform and deploying it so as to complement the firm's technology position reduces design uncertainty, promoting reengineering success. [source] Technology-Based New Product Development Partnerships,DECISION SCIENCES, Issue 2 2006John E. Ettlie ABSTRACT Hypotheses were developed to capture the dynamic capabilities that result from interfirm partnerships during the joint new product development (NPD) process,the ability to build, integrate, and reconfigure existing resources to adapt to rapidly changing environments. These capabilities, in turn, were proposed to have a positive impact on NPD performance outcomes: (a) proportion of new product success and (b) superior new product commercialization. In contexts where the locus of innovation is rapidly changing, the impact of interfirm NPD dynamic capabilities was hypothesized to be diminished in high-technology contexts, especially for buyers (original equipment manufacturers) and to a lesser extent for suppliers. Still, technology-based interfirm NPD partnerships were predicted to ultimately outperform low-technology ones in both NPD performance outcomes. Finally, information technology (IT) support for NPD was hypothesized to influence the interfirm NPD partnership's dynamic capabilities. Using survey data from 72 auto company managers and their suppliers, the proposed model in which IT support for NPD influences the success of interfirm NPD partnerships through the mediating role of interfirm NPD partnership dynamic capabilities in high- and low-technology contexts was generally supported. The results shed light on the nature of technology-based interfirm NPD partnerships and have implications for their success. Theoretical and managerial implications are discussed. [source] Multiple Conceptualizations of Small Business Web Use and Benefit*DECISION SCIENCES, Issue 3 2003Kurt A. Pflughoeft ABSTRACT Small businesses play an important role in the U.S. economy and there is anecdotal evidence that use of the Web is beneficial to such businesses. There is, however, little systematic analysis of the conditions that lead to successful use of and thereby benefits from the Web for small businesses. Based on the innovation adoption, organizations, and information systems (IS) implementation literature, we identify a set of variables that are related to adoption, use, and benefits of information technology (IT), with particular emphasis on small businesses. These variables are reflective of an organization's contextual characteristics, its IT infrastructure, Web use, and Web benefits. Since the extant research does not suggest a single theoretical model for Web use and benefits in the context of small businesses, we adopt a modeling approach and explore the relationships between "context-IT-use-benefit" (CIUB) through three models,partial-mediator, reduced partial-mediator, and mediator. These models posit that the extent of Web use by small businesses and the associated benefits are driven by organizations' contextual characteristics and their IT infrastructure. They differ in the endogeneity/exogeneity of the extent of IT sophistication, and in the direct/mediated effects of organizational context. We examine whether the relationships between variables identified in the literature hold within the context of these models using two samples of small businesses with national coverage, including various sizes, and representing several industry sectors. The results show that the evidence for patterns of relationships is similar across the two independent samples for two of these models. We highlight the relationships within the reduced partial-mediator and mediator models for which conclusive evidence are given by both samples. Implications for small business managers and providers of Web-based technologies are discussed. [source] An Exploratory Analysis of the Value of the Skills of IT Personnel: Their Relationship to IS Infrastructure and Competitive AdvantageDECISION SCIENCES, Issue 1 2001Terry Anthony Byrd Abstract Determining and assessing the requisite skills of information technology (IT) personnel have become critical as the value of IT has risen in modern organizations. In addition to technical skills traditionally expected of IT personnel, softer skills like managerial, business, and interpersonal skills have been increasingly cited in previous studies as mandatory for these employees. This paper uses a typology of IT personnel skills,technology management skills, business functional skills, interpersonal skills, and technical skills,and investigates their relationships to two information systems (IS) success variables, IS infrastructure flexibility and the competitive advantage provided by IS. The study investigates these relationships using the perceptions of chief information officers (CIOs) from mostly Fortune 2000 companies. The contributions of this study are: IT personnel skills do affect IS success, technical skills are viewed as the most important skill set in affecting IS infrastructure flexibility and competitive advantage, and modularity is viewed as more valuable to competitive advantage than integration. Several explanations are offered for the lack of positive relationships between the softer IT personnel skills and the dimensions of IS success used in this study. [source] IRSS Psychology Theory: Telling Experiences Among Underrepresented IS DoctoratesDECISION SCIENCES JOURNAL OF INNOVATIVE EDUCATION, Issue 2 2006Fay Cobb Payton ABSTRACT With the changing demographics of the American workforce, the National Science Foundation, along with the U.S. Department of Commerce, has highlighted the shortage of minorities in information technology (IT) careers (http://www.ta.doc.gov/Reports/itsw/itsw.pdf). Using data from a 6-year period and the psychology Involvement-Regimen-Self Management-Social (IRSS) network theory as defined by Boice (1992), we discuss lessons learned from mentoring a group of Information Systems doctoral students who are members of a pipeline that can potentially increase the number of underrepresented faculty in business schools and who made conscious decisions to renounce the IT corporate domain. While our lessons speak to the need for more diversity awareness, we conclude that effective mentoring for underrepresented groups can and should include faculty of color (though limited in numbers) as well as majority faculty who are receptive to the needs and cultural differences of these student groups. Lastly, we draw on the work of Ethnic America to provide additional insight into our findings that are not offered by IRSS network theory. [source] A national survey of the current state of screening services for diabetic retinopathy: ABCD,Diabetes UK survey of specialist diabetes services 2006DIABETIC MEDICINE, Issue 12 2009D. K. Nagi Abstract The main aims were to ascertain the progress made in the implementation of retinal screening services and to explore any barriers or difficulties faced by the programmes. The survey focused on all the essential elements for retinal screening, including assessment and treatment of screen-positive cases. Eighty-five per cent of screening programmes have a coordinated screening service and 73% of these felt that they have made significant progress. Eighty-five per cent of screening units use ,call and recall' for appointments and 73.5% of programmes follow the National Screening Committee (NSC) guidance. Although many units worked closely with ophthalmology, further assessment and management of screen-positive patients was a cause for concern. The fast-track referral system, to ensure timely and appropriate care, has been difficult to engineer by several programmes. This is demonstrated by 48% of programmes having waiting lists for patients identified as needing further assessment and treatment for retinopathy. Ophthalmology service for people with diabetic retinopathy was provided by a dedicated ophthalmologist in 89.4% of the programmes. Sixty-six per cent of the programmes reported inadequate resources to sustain a high-quality service, while 26% highlighted the lack of infrastructure and 49% lacked information technology (IT) support. In conclusion, progress has been made towards establishing a national screening programme for diabetic retinopathy by individual screening units, with a number of programmes providing a structured retinal screening service. However, programmes face difficulties with resource allocation and compliance with Quality Assurance (QA) standards, especially those which apply to ophthalmology and IT support. Screening programmes need to be resourced adequately to ensure comprehensive coverage and compliance with QA. [source] ENDOSCOPIC MUCOSAL RESECTION AND SUBMUCOSAL DISSECTION METHOD FOR LARGE COLORECTAL TUMORSDIGESTIVE ENDOSCOPY, Issue 2004Yasushi Sano ABSTRACT The goal of endoscopic mucosal resection (EMR) is to allow the endoscopist to obtain tissue or resect lesions not previously amenable to standard biopsy or excisional techniques and to remove malignant lesions without open surgery. In this article, we describe the results of conventional EMR and EMR using an insulation-tipped (IT) electrosurgical knife (submucosal dissection method) for large colorectal mucosal neoplasms and discuss the problems and future prospects of these procedures. At present, conventional EMR is much more feasible than EMR using IT-knife from the perspectives of time, money, complication, and organ preservation. However, larger lesions tend to be resected in a piecemeal fashion; and it is difficult to confirm whether EMR has been complete. For accurate histopathological assessment of the resected specimen en bloc EMR is desirable although further experience is needed to establish its safety and efficacy. Further improvements of in EMR with special knife techniques are required to simply and safely remove large colorectal neoplasms. [source] Trust, Transactions, and Information Technologies in the U.S. Logistics IndustryECONOMIC GEOGRAPHY, Issue 2 2007Yuko Aoyama Abstract: How does information technology (IT) alter the organizational dynamics in an industry? In this article, we examine changes in competition and interfirm relations in the U.S. logistics industry, particularly whether "trust-based" interfirm relationships are being substituted by "competition-based" relationships and the rationale for outsourcing. We also examine how new IT tools and outsourcing interact and how logistics contracts, the size of firms, and knowledge lead to integration or disintegration within the industry. The results of our research demonstrate that while the use of IT tools is widespread, traditional trust-based relationships exhibit a considerable resilience in the logistics industry. The industry is also undergoing a complex process of restructuring in response to technological change, on the one hand, and the persistence of geographic and functional specialization, on the other hand. The industry's focus on the delivery of high-quality services, coupled with excess capacity in the industry in the past few years, has contributed to these contradictory trends. As a result, elimination of the middleman has not been as widely observed as expected. [source] Estimating the Fractional Order of Integration of Yields in the Brazilian Fixed Income MarketECONOMIC NOTES, Issue 3 2007Benjamin M. Tabak This paper presents evidence that yields on the Brazilian fixed income market are fractionally integrated, and compares the period before and after the implementation of the Inflation Targeting (IT) regime. The paper employs the commonly used GPH estimator and recently developed wavelets-based estimator of long memory. Empirical results suggest that interest rates are fractionally integrated and that interest rate spreads are fractionally integrated, with a higher order of integration in the period after the implementation of the IT regime. These results have important implications for the development of macroeconomic models for the Brazilian economy and for long-term forecasting. Furthermore, they imply that shocks to interest rates are long-lived. [source] Information Technology and Productivity Changes in the Banking IndustryECONOMIC NOTES, Issue 1 2007Luca Casolaro This paper analyses the effects of investment in information technologies (IT) in the financial sector using micro-data from a panel of 600 Italian banks over the period 1989,2000. Stochastic cost and profit functions are estimated allowing for individual banks' displacements from the best practice frontier and for non-neutral technological change. The results show that both cost and profit frontier shifts are strongly correlated with IT capital accumulation. Banks adopting IT capital-intensive techniques are also more efficient. On the whole, over the past decade IT capital-deepening contribution to total factor productivity growth of the Italian banking industry can be estimated in a range between 1.3 and 1.8 per cent per year. [source] Lactose intolerance: analysis of underlying factorsEUROPEAN JOURNAL OF CLINICAL INVESTIGATION, Issue 1 2003R. J. Vonk Abstract Background We studied the degree of lactose digestion and orocecal transit time (OCTT) as possible causes for the variability of symptoms of lactose intolerance (LI) in a sample of a population with genetically determined low lactase activity. Methods Lactose digestion index (LDI) was measured by the recently developed 13C-lactose/2H-glucose test. The OCTT was determined using the breath hydrogen test. Based on a 6-h symptom score (SSC) after a challenge dose of 25 g of lactose the subjects were divided into a tolerant group (T: n= 15; SSC = 0) and an intolerant group (IT: n= 28; SSC 1,40). The intolerant group was subdivided according to the severity of symptoms: group ITa (n = 17; mild symptoms without diarrhoea) and group ITb (n = 11; with diarrhoea). Results The LDI was lower in the intolerant group (0·34 ± 0·14) (mean ± SD) than in the tolerant group (0·47 ± 0·14) (P = 0·008). The OCTT of group IT (60, 30,90 min) (median, quartiles) was significantly shorter than that of group T (105, 60,120 min) (P = 0·003) and was positively correlated with the LDI (P = 0·050). In groups ITa and ITb the OCTT (60, 30,90 min; 60, 26,83 min) and LDI (0·30 ± 0·14; 0·39 ± 0·14) were similar. Conclusions Lactose digestion capacity, which is determined by small intestinal lactase activity as well as by OCTT, affects the occurrence of lactose intolerance. However, the major difference in intolerance symptoms is caused by differences in the colonic processing of maldigested lactose. [source] Results of the PETHEMA ALL-96 trial in elderly patients with Philadelphia chromosome-negative acute lymphoblastic leukemiaEUROPEAN JOURNAL OF HAEMATOLOGY, Issue 2 2007Juan-Manuel Sancho Abstract Background and aim:,Only 20,30% of elderly patients with acute lymphoblastic leukemia (ALL) are enrolled in clinical trials because of co-morbid disorders or poor performance status. We present the results of treatment of Philadelphia chromosome-negative (Ph,) ALL patients over 55 yr treated in the PETHEMA ALL-96 trial. Patients and methods:,From 1996 to 2006, 33 patients 55 yr with Ph, ALL were included. Induction therapy was vincristine, daunorubicin, prednisone, asparaginase, and cyclophosphamide over 5 weeks. Central nervous system (CNS) prophylaxis involved triple intrathecal (IT) therapy, 14 doses over the first year. Consolidation-1 included mercaptopurine, methotrexate, teniposide and cytarabine, followed by one consolidation-2 cycle similar to the induction cycle. Maintenance consisted of mercaptopurine and methotrexate up to 2 yr in complete remission (CR) with monthly reinduction cycles (vincristine, prednisone and asparaginase) during the first year. Results:,Median (range) age was 65 yr (56,77). Phenotype (30 patients): early-pre-B 7, common/pre-B 18, T 5. Cytogenetics (28 patients): normal 12, complex 10, t(4;11) 2 and other 4. CR was achieved in 19/33 (57.6%) patients, early death occurred in 12 (36.4%) and 2 (6%) were resistant. Overall survival and disease-free survival probabilities (2 yr, 95% CI) were 39% (21%,57%) and 46% (22%,70%), respectively (median follow up of 24 months). Removal of asparaginase and cyclophosphamide from the induction decreased induction death (OR 0.119, CI 95% 0.022,0.637, P = 0.013) and increased survival (20% vs. 52%, P = 0.05). Conclusions:,The prognosis of elderly Ph, ALL patients is poor. In this study, less intensive induction decreased toxic death, allowing delivery of planned consolidation therapy and increased survival probability. [source] Intrathecal donor lymphocyte infusion for the treatment of suspected refractory lymphomatous meningitis: a case reportEUROPEAN JOURNAL OF HAEMATOLOGY, Issue 6 2006N. Meuleman Abstract:, A 43-year-old female with large T-cell non-Hodgkin's lymphoma and central nervous system (CNS) involvement underwent HLA-identical-sibling peripheral blood stem cell transplantation (SCT) during her third complete remission. She presented a possible refractory CNS relapse 5 months after the transplant. She was then treated with intrathecal (IT) donor lymphocyte infusions (DLI). No side effects were observed after three DLI injections. The patient died 13 months later from infectious complications with no evidence of progressive disease. To our knowledge, this is the first case report of IT DLI for possible refractory lymphomatous meningitis. [source] Comparison of near-infrared emission spectroscopy and the Rancimat method for the determination of oxidative stabilityEUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, Issue 1 2007Fabiano B. Gonzaga Abstract This work presents a comparison between a new method for the determination of the oxidative stability of edible oils at frying temperatures, based on near-infrared emission spectroscopy (NIRES), and the Rancimat method at 110,,°C. In the NIRES-based method, the induction time (IT) is determined by means of the variation of the emission band at 2900,nm during heating at 160,,°C. The comparison between the IT values obtained with the two methods for 12,samples of edible oils shows some correlation for samples of the same type once there is an agreement on the sequence of highest to lowest IT values between the methods, but a poor correlation considering all samples (correlation coefficient of 0.78). This lack of correlation demonstrates that the results obtained with the Rancimat method cannot be used as an indication of the oxidative stability, or the resistance to degradation, of edible oils at frying temperatures. The difference in the heating temperatures used in the two methods leads to 20,36,times higher IT values for the Rancimat method in relation to the NIRES-based method, but with similar repeatabilities (2.0 and 2.8%, respectively). [source] A pilot study on systemic thrombolysis followed by low molecular weight heparin in ischemic strokeEUROPEAN JOURNAL OF NEUROLOGY, Issue 10 2006R. Mikulík Low molecular weight heparin (LMWH) administered immediately after intravenous thrombolysis (IT) may reduce the risk of arterial re-occlusion. Its benefit, however, may not outweigh the risk of intracranial hemorrhage (ICH). We sought preliminary data regarding safety of this combined therapy in an open-label, non-randomized study. The patients received either a standard anticoagulation (AC) starting 24 h after IT (the standard AC group) or AC with 2850 IU of nadroparin, given every 12 h immediately after IT (the early AC group). Sixty patients received IT treatment: 25 in the standard AC group [mean age 66, median National Institutes of Health Stroke Scale (NIHSS) 13, 64% men] and 35 in the early AC group (mean age 68, median NIHSS 13, 69% men). Symptomatic ICH occurred in one patient (4%) in the standard AC group and three patients (8.6%) in the early AC group [odds ratio (OR) 1.8; 95%CI 0.2,12.8]. At 3 months, nine patients in the standard AC group (36%) and 16 patients in the early AC group (45.7%) achieved a modified Rankin scale 0 or 1 (OR 1.2; 95%CI 0.5,3.2). Our study suggests that treatment with LMWH could be associated with higher odds of ICH, although it may not necessarily lead to a worse outcome. This justifies larger clinical trials. [source] Tuning for shape dimensions in macaque inferior temporal cortexEUROPEAN JOURNAL OF NEUROSCIENCE, Issue 1 2005Greet Kayaert Abstract It is widely assumed that distributed bell-shaped tuning (e.g. Radial Basis functions) characterizes the shape selectivity of macaque inferior temporal (IT) neurons, analogous to the orientation or spatial frequency tuning found in early visual cortex. Demonstrating such tuning properties requires testing the responses of neurons for different values along dimensions of shape. We recorded the responses of single macaque IT neurons to variations of a rectangle and a triangle along simple shape dimensions, such as taper and axis curvature. The neurons showed systematic response modulation along these dimensions, with the greatest response, on average, to the highest values on the dimensions, e.g. to the most curved shapes. Within the range of values tested, the response functions were monotonic rather than bell-shaped. Multi-dimensional scaling of the neural responses showed that these simple shape dimensions were coded orthogonally by IT neurons: the degree and direction of responses modulation (i.e. the increase or decrease of responses along a dimension) was independent for the different dimensions. Furthermore, for combinations of curvature-related and other simple shape dimensions, the joint tuning was separable, that is well predicted by the product of the tuning for each of the dimensions. The independence of dimensional tuning may provide the neural basis for the independence of psychophysical judgements of multidimensional stimuli. [source] Neural selectivity for hue and saturation of colour in the primary visual cortex of the monkeyEUROPEAN JOURNAL OF NEUROSCIENCE, Issue 5 2000Akitoshi Hanazawa Abstract In the inferior temporal (IT) cortex of monkeys, which has been shown to play a critical role in colour discrimination, there are neurons sensitive to a narrow range of hues and saturation. By contrast, neurons in the retina and the parvocellular layer of the lateral geniculate nucleus (pLGN) encode colours in a way that does not provide explicit representation of hue or saturation, and the process by which hue- and saturation-selectivity is elaborated remains unknown. We therefore tested the colour-selectivity of neurons in the primary visual cortex (V1) and compared it with those of pLGN and IT neurons. Quantitative analysis was performed using a standard set of colours, systematically distributed within the CIE (Commission Internationale de l'Eclairage)-xy chromaticity diagram. Selectivity for hue and saturation was characterized by analysing response contours reflecting the overall distribution of responses across the chromaticity diagram. We found that the response contours of almost all pLGN neurons were linear and broadly tuned for hue. Many V1 neurons behaved similarly; nonetheless, a considerable number of V1 neurons had clearly curved response contours and were selective for a narrow range of hues or saturation. The relative frequencies of neurons exhibiting various selectivities for hue and saturation were remarkably similar in the V1 and IT cortex, but were clearly different in the pLGN. Thus, V1 apparently plays a very important role in the conversion of colour signals necessary for generating the elaborate colour selectivity observed in the IT cortex. [source] Technology-Mediated Learning 10 Years Later: Emphasizing Pedagogical or Utilitarian Applications?FOREIGN LANGUAGE ANNALS, Issue 1 2007Article first published online: 31 DEC 200, Nike Arnold Abstract: In recent years, educational technology has come a long way. Technological advancements and significant investments in computer equipment and training have opened new opportunities for foreign language teachers. In addition, instructional technology (IT) is now an accepted component of teacher training and foreign language teaching. This study addresses the question how IT actually is being used for foreign language learning in higher education. It reports the findings of an online survey, which was completed by 173 college foreign language teachers. Results suggest that the vast majority of participants do use computer technology for their teaching, but at a very basic level. Teachers' IT use seems to be motivated largely by utilitarian reasons, followed by a variety of pedagogical benefits. [source] Defining Expertise in Software Development While Doing GenderGENDER, WORK & ORGANISATION, Issue 4 2007Esther Ruiz Ben The optimism regarding opportunities for women to enter the professionalization process in software development during the past years has not been fully realized and the gender gap in Germany's information technology (IT) sector still persists. Women are almost completely unrepresented in the technical fields of the German software industry, particularly in small enterprises. In this article, I firstly offer an overview of the German IT sector's development and current status. Secondly, I discuss the construction of expertise and gendered meanings in the practice of software development and related implications for the enrolment of women in this field. Gender stereotypical assumptions about expertise in the practice of software development and structural factors related to the lack of life,work balance programmes, as well as the lack of internal training in most IT companies, contribute to organizational segregation [source] Information Technology and the World Growth ResurgenceGERMAN ECONOMIC REVIEW, Issue 2 2007Dale W. Jorgenson Growth; investment; productivity; information technology Abstract. This paper analyzes the impact of investment in information technology (IT) on the recent resurgence of world economic growth. We describe the growth of the world economy, seven regions, and 14 major economies during the period 1989,2004. We allocate the growth of world output between input growth and productivity and find, surprisingly, that input growth greatly predominates! Moreover, differences in per capita output levels are explained by differences in per capita input, rather than variations in productivity. The contributions of IT investment have increased in all regions, but especially in industrialized economies and Developing Asia. [source] How a leading medical lab accrediting organization has achieved breakthrough improvement with transformational leadershipGLOBAL BUSINESS AND ORGANIZATIONAL EXCELLENCE, Issue 4 2010Tammy Roberts COLA, a leading clinical laboratory accreditation organization, faced a rapidly contracting market and worsening financial performance but was paralyzed by outmoded systems and a vision and mind-set hamstrung by attachments to past success. In an eight-year journey, leaders and staff learned to create transformative change in themselves and on key organizational fronts, subsequently generating breakthrough improvements in performance that have set COLA on a new path to success. The authors discuss the key cornerstones of transformational change; a model of transformational leadership; and the transformation cycle COLA used to integrate these with strategic/business planning, execution, and performance monitoring. They also describe COLA's key initiatives,including governance, leadership and culture, performance measurement, sales and marketing, research and development process, and IT,and present evidence of a robust business and organizational transformation at COLA. © 2010 Wiley Periodicals, Inc. [source] The uses and abuses of time: globalization and time arbitrage in India's outsourcing industriesGLOBAL NETWORKS, Issue 1 2009SHEHZAD NADEEM Abstract Globalization has undoubtedly altered our conceptions and experience of time. It has sped up the pace of life and some scholars even suggest that a new temporal order is supplanting ,natural' and pre-existing cycles and rhythms. Yet time is not dissolved in the global circuits of capital. Rather, globalization has brought about a complex mixture of temporal orientations; the workplaces of ,new economy', for example, are traversed by novel and retrograde modes of work pace, rhythm and time-discipline. In this article, I explore the temporal implications of the outsourcing of information technology-based service work to India. Drawing on fieldwork and interviews with workers, managers and executives in the Indian IT and Business Processing Outsourcing industries, I address the following questions: (1) How are corporations using time arbitrage to reap the full benefits of a globally dispersed labour pool? (2) What impacts are these temporal changes having on the health and social lives of Indian workers? For corporations, time arbitrage means increased efficiency and cost-savings. But for workers, it results in long hours, an intense work pace, and temporal displacement. Night-shift employees, such as call centre workers, are particularly vulnerable to such displacement, as manifested in health and safety problems and social alienation. Globalization therefore does not entail the loosening of temporal chains, but their reconfiguration: a combination both rigid and flexible that binds even as it liberates. [source] | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||