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Isoquinoline Derivatives (isoquinoline + derivative)

Distribution by Scientific Domains
Chemistry100%

Selected Abstracts

Asymmetric Synthesis of Isoquinoline Derivatives from Amino Acids

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 4 2005
Oxana Sieck
Abstract Reaction of isoquinolines 1 with N -arylsulfonylamino acid fluorides 2 provides a highly stereoselective access to new dihydroimidazo[2,1 -a]isoquinolin-3-ones 5 via intermediate N -acylisoquinolinium salts 3. Addition reactions to the en-amine double bond, such as hydrogenation or epoxidation with dimethyldioxirane, leads to tetrahydroimidazo[2,1 -a]isoquinoline-3-ones 6, 7 and oxiranes 8, respectively. Opening of the oxirane ring of the 8 with nucleophiles allows the synthesis of hydroxytetrahydroimidazo[2,1 -a]isoquinolin-3-ones 10 or 12 or of the polycyclic 1,4-dioxane 13 in high stereoselectivity. The regioselectivity of the oxiran ring opening depends on the kind of nucleophile and the conditions. Reaction of dihydroisoquinoline with O -TBDMS-mandelic acid chloride 15 leads to a tetrahydrooxazolo[2,3 -a]isoquinoline 17 with opposite facial selectivity as compared with dihydroimidazo[2,1 -a]isoquinolin-3-ones 5. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005) [source]

ChemInform Abstract: A Novel and Green Method for the Synthesis of Highly Substituted Isoquinoline Derivatives in Ionic Liquid.

CHEMINFORM, Issue 15 2010
Xiang-Shan Wang
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

ChemInform Abstract: Synthesis of Isoquinoline Derivatives via Ag-Catalyzed Cyclization of 2-Alkynyl Benzyl Azides.

CHEMINFORM, Issue 33 2009
Yan-Ning Niu
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

ChemInform Abstract: Orthogonal Synthesis of Isoindole and Isoquinoline Derivatives from Organic Azides.

CHEMINFORM, Issue 26 2009
Benjamin Wei-Qiang Hui
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

ChemInform Abstract: Synthesis of Isoquinoline Derivatives of Quinoxaline-2-one from Pyrrolo[2,1-a]isoquinoline-2,3-diones and o-Phenylenediamine.

CHEMINFORM, Issue 4 2009
O. V. Surikova
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

A Three-Component Approach to Isoquinoline Derivatives by Cycloaddition/Heck Reaction Sequence.

CHEMINFORM, Issue 39 2007
Masato Oikawa
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]

Cross-Metathesis Reaction of 1-Allylated ,-Carboline and Isoquinoline Derivatives.

CHEMINFORM, Issue 43 2005
Kazuhiro Nagata
Abstract For Abstract see ChemInform Abstract in Full Text. [source]

Synthetic Studies on Isoquinoline Derivatives with Multidrug Resistance (MDR) Modulating Activity.

CHEMINFORM, Issue 21 2004
Chen Ma
Abstract For Abstract see ChemInform Abstract in Full Text. [source]

ChemInform Abstract: Structure,Activity Relationships of New Inhibitors of Mammalian 2,3-Oxidosqualene Cyclase Designed from Isoquinoline Derivatives

CHEMINFORM, Issue 32 2002
Jean Binet
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

ChemInform Abstract: Synthesis of Pyridine and Isoquinoline Derivatives by the Palladium-Catalyzed Cyclization of Olefinic Ketone O-Pentafluorobenzoyloximes

CHEMINFORM, Issue 44 2001
Hironori Tsutsui
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

ChemInform Abstract: Formation of Isoquinoline Derivatives by the Irradiation of N-Acetyl-,-dehydrophenylalanine Ethyl Ester and Its Derivatives.

CHEMINFORM, Issue 6 2001
Hideki Hoshina
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

Synthesis of the Carbon Framework of the Stephaoxocanes Employing a Sequential RCM/Pomeranz,Fritsch Approach

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 31 2007
Andrea B. J. Bracca
Abstract The syntheses of two cyclodeca[ij]isoquinoline derivatives, which embody the carbon framework of stephaoxocanidine, excentricine and the recently isolated stephalonganines A, B and C, are reported. The target tricyclic compounds were prepared from isovanillin, employing a ring-closing metathesis approach towards the synthesis of a benzocyclodecane-type common intermediate; different modifications of thePomeranz,Fritsch protocol allowed the installation of the heterocyclic ring.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007) [source]

Intramolecular photoreactions of thiohomophthalimides with an alkenyl group in their N -Side chain.

JOURNAL OF HETEROCYCLIC CHEMISTRY, Issue 2 2005
Regioselective synthesis of heterocycle-fused isoquinoline derivatives through [2+2] photocycloaddition
Upon irradiation, thiohomophthalimides with an alkenyl group in their N -side chain or at the benzylic position give tricyclic isoquinoline derivatives through regioselective intramolecular [2+2] cycloaddition or Norrish type II reaction, respectively, in good yields. [source]

Electron ionization mass spectra of phosphorus-containing heterocycles.

RAPID COMMUNICATIONS IN MASS SPECTROMETRY, Issue 23 2006

The 1,3,4,2-oxadiazaphosphinane 2-oxides differ not only in the relative configuration of the P atom (R* or S*), but also in many other ways such as the ring size, ring fusion, P substitution and bridgehead N atom whose effects on their fragmentations have been studied. Some fragmentations resembled those of 3,1,2-oxazaphosphinane 2-oxides and 1,3,2-diazaphosphinane-2-oxides, but new routes were also found, initiated by ionization at the bridgehead N atom. The relative abundances of the molecular ions and some fragment ions allowed the differentiation of cis-trans epimers. Compounds with n,=,2 and R,,N(CH2CH2Cl)2, and linearly or angularly isoquinoline-fused isomers in most cases, gave more numerous ions with lower relative abundances than the other compounds in this series. Only the isoquinoline derivatives provided fragments resulting from ionization of the aromatic part of the molecule. Copyright © 2006 John Wiley & Sons, Ltd. [source]