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Inner Workings (inner + working)
Selected AbstractsTowards second-generation proteome analysis of murine enamel-forming cellsEUROPEAN JOURNAL OF ORAL SCIENCES, Issue 2006Jonathan E. Mangum Proteome analysis of rat enamel-forming cells, initiated over a decade ago, has provided valuable insights to enamel biology. In preparation for a more comprehensive, second-generation proteomic exploration, we evaluated an updated microsample-profiling strategy that comprises sequential extraction of enamel epithelium, parallel one- and two-dimensional gel electrophoresis, and mass spectrometric sequence analysis. The results indicated that several hundred proteins, representing various cellular compartments (including membranes), are amenable to identification with a starting tissue volume of <,10 µl. With its increased proteomic depth and breadth, this straightforward approach constitutes a major advance from the first-generation work (10-fold increased proteome coverage), although care was needed to ensure a comparably high stringency of protein identification. Expression proteomics has an exciting potential to elucidate the inner workings of murine enamel epithelial cells, leading to an improved understanding of enamel in health and disease. [source] Sliding mesh algorithm for CFD analysis of helicopter rotor,fuselage aerodynamicsINTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN FLUIDS, Issue 5 2008R. Steijl Abstract The study of rotor,fuselage interactional aerodynamics is central to the design and performance analysis of helicopters. However, regardless of its significance, rotor,fuselage aerodynamics has so far been addressed by very few authors. This is mainly due to the difficulties associated with both experimental and computational techniques when such complex configurations, rich in flow physics, are considered. In view of the above, the objective of this study is to develop computational tools suitable for rotor,fuselage engineering analysis based on computational fluid dynamics (CFD). To account for the relative motion between the fuselage and the rotor blades, the concept of sliding meshes is introduced. A sliding surface forms a boundary between a CFD mesh around the fuselage and a rotor-fixed CFD mesh which rotates to account for the movement of the rotor. The sliding surface allows communication between meshes. Meshes adjacent to the sliding surface do not necessarily have matching nodes or even the same number of cell faces. This poses a problem of interpolation, which should not introduce numerical artefacts in the solution and should have minimal effects on the overall solution quality. As an additional objective, the employed sliding mesh algorithms should have small CPU overhead. The sliding mesh methods developed for this work are demonstrated for both simple and complex cases with emphasis placed on the presentation of the inner workings of the developed algorithms. Copyright © 2008 John Wiley & Sons, Ltd. [source] Task-Based Assessment Centers: Empirical support for a systems modelINTERNATIONAL JOURNAL OF SELECTION AND ASSESSMENT, Issue 2 2010Duncan J. R. Jackson Task-based assessment centers (TBACs) have been suggested to hold promise for practitioners and users of real-world ACs. However, a theoretical understanding of this approach is lacking in the literature, which leads to misunderstandings. The present study tested aspects of a systems model empirically, to help elucidate TBACs and explore their inner workings. When applied to data from an AC completed by 214 managers, canonical correlation analysis revealed that extraversion, abstract reasoning, and verbal reasoning, conceptualized as inputs into a system, explained around 21% of variance in manifest assessment center behavior. Behavior, in this regard, was found to consist of both general and situationally specific elements. Results are discussed in terms of their support for a systems model and as they pertain to the literature on TBACs. [source] SPIDER: A decade of measuring ultrashort pulsesLASER PHYSICS LETTERS, Issue 4 2008M.E. Anderson Abstract It was ten years ago in Rochester, New York that the first SPIDER was built. This simple acronym belies the subtleties of its inner workings; Spectral Phase Interferometry for Direct Electric-field Reconstruction (the "f" in field conveniently missed the cut) is a device that measures ultrashort pulses, utilizing spectral shearing interferometry and directly recovering the spectral phase. The very first SPIDER apparatus occupied nearly half an optical table, used a scanning monochromator, and had no computerized inversion routine. In the intervening decade, SPIDER has grown up. It has found a strong foothold in ultrafast laboratories throughout the world. Multiple groups have found useful new applications with this vital measurement tool, while others have contributed to the improvement of SPIDER itself, reaching to ever shorter pulses, new wavelength regimes, and making devices more sensitive, robust, smaller and faster. It also adapts to a field of research that changes rapidly. It was first designed to track and quantify the remaining spectral phase in a pulse to perfect its compression. In ten years, with the advent of pulse shapers, the real benefits of field diagnostics are becoming apparent. We have shifted away from the race towards the shortest IR pulse to a wide use of complex shaped pulses in almost every spectral range from far IR to XUV. But the quest of the shortest pulse is not over and new compression techniques utilize really broad spectra that are highly structured. All these applications provide new challenges for characterization techniques. (© 2008 by Astro Ltd., Published exclusively by WILEY-VCH Verlag GmbH & Co. KGaA) [source] The State of Biological Anthropology in 2008: Is Our Discipline Strong and Our Cause Just?AMERICAN ANTHROPOLOGIST, Issue 2 2009Nicholas Malone ABSTRACT Biological anthropologists inform a largely professional discourse on the evolutionary history of our species. In addition, aspects of our biology, the ways in which we vary, and certain patterns of behavior are the subjects of a more public and popular conversation. The social contexts in which we work not only define our times but also produce the anthropologists that in turn construct an emergent understanding of our species' (and our societies') inner workings. In this review of scholarly production, I focus on developments within a selection of "sub-subdisciplines" that were particularly influential in bending the arc of biological anthropology in 2008, namely: evolutionary medical anthropology, anthropological neuroscience, forensic anthropology, primatology, and paleoanthropology. Ultimately, this review demonstrates, yet again, anthropology's great contribution: the ability to incorporate new technologies and research methodologies into a synthetic and integrative interdisciplinary approach toward the elucidation of human behavior, evolution, and biocultural engagements with the environment. [Keywords: biological anthropology, year in review, 2008, science and society] [source] Knowing What Really HappenedPRESIDENTIAL STUDIES QUARTERLY, Issue 4 2002Michael Beschloss Historians of the past have depended upon the creation and later the release of private diaries, letters, memos, and other records that shed light on the inner workings of a president's mind and his behind-the-scenes actions. Due to a number of forces, such records are increasingly less likely to be created or released, preventing scholars from having the kind of understanding of the hidden core of a presidency that they once were able to command. [source] The Poet and the Warrior: The Symbolist Context of Myth in Stefan George's Early VerseTHE GERMAN QUARTERLY, Issue 2 2009Natasha Grigorian The article is the first study of its kind to analyze the mythical strata in the early verse of Stefan George (1868,1933) in the context of French and international Symbolism. Parallels are drawn primarily with the work of Moréas and Heredia, whose inspiration was vital for George in his pioneering adaptation of the French Symbolist credo to German poetry. A close comparison of George's verse with that of the two French poets is further illuminated by references to the painting of Moreau and Böcklin. The article innovatively employs such conceptual tools as syncretism and mytheme to shed light on the inner workings of George's poetic procedure, uncovering a dialectical struggle between chaos and harmony that underlies his verse and shapes his Symbolist method. In a broader context, the article helps to understand the ways in which George's work re-defined German poetry at the dawn of the twentieth century. [source] Analytic impasse and the third: Clinical implications of intersubjectivity theoryTHE INTERNATIONAL JOURNAL OF PSYCHOANALYSIS, Issue 2 2006LEWIS ARON The author examines the notion of the third within contemporary intersubjectivity theory. He utilizes a variety of metaphors (the triangle, the seesaw, strange attractors, and the compass) in an effort to explain this often misunderstood concept in a clear and readily usable manner. An argument is made to the effect that intersubjectivity theory has direct implications for clinical practice, and that the notion of the third is particularly useful in understanding what happens in and in resolving clinical impasses and stalemates. Specifi cally, the author suggests that certain forms of self-disclosure are best understood as attempts to create a third point of reference, thus opening up psychic space for self-refl ection and mentalization. He provides a clinical case as well as a number of briefer vignettes to illustrate the theoretical concepts and to suggest specifi c modifi cations of the psychoanalyst's stance that give the patient greater access to the inner workings of the analyst's mind. This introduces a third that facilitates the gradual transformation from relations of complementarity to relations of mutuality. [source] Ancient planets and cosmic vagabondsASTRONOMY & GEOPHYSICS, Issue 5 2003Peter Bond Strange goings-on in space are revealed by powerful instruments in concert, observing the same phenomena at the same time and in consequence, revealing the inner workings of the stars. Peter Bond reports. [source] | |||||||||||||