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Implant Stability (implant + stability)
Kinds of Implant Stability Terms modified by Implant Stability Selected AbstractsImplant Stability during Initiation and Resolution of Experimental Periimplantitis: An Experimental Study in the DogCLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Issue 3 2005Lars Sennerby DDS ABSTRACT Background: Histologic studies have demonstrated the possibility to reestablish direct bone-implant contacts after ligature-induced periimplantitis. The influence of the reosseointegration on the stability of implants is not known. Purpose: The aim of the present investigation was to study bone tissue and associated implant stability alterations that occurred during induction and resolution of periimplantitis using resonance frequency analysis (RFA), radiography, and histology. Materials and Methods: Three implants with smooth (turned) or roughened (SLA®) surfaces were placed in each side of the edentulous mandible of four dogs. Experimental periimplantitis was induced for 3 months. Five weeks later, the animals were treated with antibiotics and surgical therapy and were followed for another 6 months. Periapical radiographs and RFA were used to evaluate marginal bone levels and implant stability throughout the study period. After termination, the tissue-implant interface was evaluated by light microscopy in ground sections. Results: There was a linear relationship between radiographic and RFA findings because continuous loss of marginal bone and a decrease in implant stability were observed for both implant surfaces during the periimplantitis period. Antibiotic treatment and surgical therapy resulted in some reosseointegration, which was more marked for the SLA surface. The resonance frequency values corresponded well to the histometric measurements because reosseointegration resulted in an increase in implant stability. Conclusions: The findings from the present study indicate a linear relationship between marginal bone level and resonance frequency value. It is suggested that the RFA technique is sensitive and may be used to detect even a minor change in the level of bone-implant contact. [source] Effects of Implant Design and Surface on Bone Regeneration and Implant Stability: An Experimental Study in the Dog MandibleCLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Issue 1 2001Lars Rasmusson DMD ABSTRACT Background: Previous experimental studies have shown a higher degree of bone-implant contact for surface-enlarged implants compared with machined implants. Yet, there is insufficient evidence that such implants show higher stability and an increased survival rate. Purpose: The purpose of this investigation was to study the integration and stability of grit-blasted implants with retention elements on the implant neck, with and without marginal bone defects, compared with machined implants without retention elements. Materials and Methods: After tooth extraction of the mandibular premolars in six dogs, two grit-blasted, partly microthreaded Astra Tech implants and one standard Branemark implant were bilaterally placed in each dog. On one side, 3 ± 3 mm large buccal defects were created, to expose three to four implant threads. The contralateral side served as control, and no defects were made. The animals were sacrificed after 4 months of healing. Implant stability was measured using resonance frequency analysis at implant installation and after 4 months of healing. Histologic and histomorpho-metric evaluation was made after 4 months of healing. Results: Resonance frequency analysis indicated that all implants in the test and control groups were osseointegrated after 4 months, with a tendency toward higher implant stability for the Astra Tech implants. There was a statistically significant higher increase in resonance frequency for the Astra test implants compared with their corresponding controls. Histology and histomorphometry showed well-integrated implants with varying degrees of bone repair at the defect sites. The greater bone-implant contact for the Astra implants was statistically significant. No significant difference between the implants in amount of bone filling the threads was recorded. Conclusions: The Astra Tech implants tested showed a higher degree of bone,implant contact and higher level of bone regenerated at defect sites compared with the Brånemark implants. Resonance frequency analysis demonstrated a significantly higher increase in the Astra test implants compared with their control groups than did the Brånemark test implants versus their controls. [source] Increased bone formation around coated implantsJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 8 2009Bernd Stadlinger Abstract Aim: We hypothesized that coating threaded, sandblasted acid-etched titanium implants with collagen and chondroitin sulphate (CS) increases bone formation and implant stability, compared with uncoated controls. Materials and Methods: Three different implant surface conditions were applied: (1) sandblasted acid-etched (control), (2) collagen/chondroitin sulphate (low-dose , CS1), (3) collagen/chondroitin sulphate (high-dose , CS2). Sixty 9.5 mm experimental implants were placed in the mandible of 20 minipigs. Bone,implant contact (BIC) and relative peri-implant bone-volume density (rBVD , relation to bone-volume density of the host bone) were assessed after 1 and 2 months of submerged healing. Implant stability was measured by resonance frequency analysis (RFA). Results: After 1 month, coated implants had significantly more BIC compared with controls (CS1: 68%, p<0.0001, CS2: 63%, p=0.009, control: 52%). The rBVD was lower for all surface conditions, compared with the hostbone. After 2 months, BIC increased for all surfaces. No significant differences were measured (CS1: 71%, p=0.016, CS2: 68%, p=0.67, control: 63%). The rBVD was increased for coated implants. RFA values were 71,77 at implantation, 67,73 after 1 month and 74,75 after 2 months. Differences in rBVD and RFA were not statistically significant. Conclusions: Data analysis suggests that collagen/CS has a positive influence on bone formation after 1 month of endosseous healing. [source] Bone Reformation and Implant Integration following Maxillary Sinus Membrane Elevation: An Experimental Study in PrimatesCLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Issue 1 2006Vinicius C Palma DDS ABSTRACT Background:, Recent clinical studies have described maxillary sinus floor augmentation by simply elevating the maxillary sinus membrane without the use of adjunctive grafting materials. Purpose:, This experimental study aimed at comparing the histologic outcomes of sinus membrane elevation and simultaneous placement of implants with and without adjunctive autogenous bone grafts. The purpose was also to investigate the role played by the implant surface in osseointegration under such circumstances. Materials and Methods:, Four tufted capuchin primates had all upper premolars and the first molar extracted bilaterally. Four months later, the animals underwent maxillary sinus membrane elevation surgery using a replaceable bone window technique. The schneiderian membrane was kept elevated by insertion of two implants (turned and oxidized, Brånemark System®, Nobel Biocare AB, Göteborg, Sweden) in both sinuses. The right sinus was left with no additional treatment, whereas the left sinus was filled with autogenous bone graft. Implant stability was assessed through resonance frequency analysis (OsstellTM, Integration Diagnostics AB, Göteborg, Sweden) at installation and at sacrifice. The pattern of bone formation in the experimental sites and related to the different implant surfaces was investigated using fluorochromes. The animals were sacrificed 6 months after the maxillary sinus floor augmentation procedure for histology and histomorphometry (bone-implant contact, bone area in threads, and bone area in rectangle). Results:, The results showed no differences between membrane-elevated and grafted sites regarding implant stability, bone-implant contacts, and bone area within and outside implant threads. The oxidized implants exhibited improved integration compared with turned ones as higher values of bone-implant contact and bone area within threads were observed. Conclusions:, The amount of augmented bone tissue in the maxillary sinus after sinus membrane elevation with or without adjunctive autogenous bone grafts does not differ after 6 months of healing. New bone is frequently deposited in contact with the schneiderian membrane in coagulum-alone sites, indicating the osteoinductive potential of the membrane. Oxidized implants show a stronger bone tissue response than turned implants in sinus floor augmentation procedures. [source] Report of a Case Receiving Full-Arch Rehabilitation in Both Jaws Using Immediate Implant Loading Protocols: A 1-Year Resonance Frequency Analysis Follow-UpCLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Issue 1 2006Michael Portmann DDS ABSTRACT Background:, Immediate occlusal implant loading has been documented as a viable treatment option for various indications. However, documentations related to full-arch rehabilitation are usually limited to treatment of one jaw at a time, thereby leaving the opposing dentition unchanged. Furthermore, clinical documentation using traditional, well-accepted measuring techniques may not be adequate when it comes to short-term evaluation of the success or failure of implants subjected to immediate occlusal loading. Purpose:, The purpose of this case report is to (1) present an implant stability follow-up of a patient receiving an immediate, implant-supported full-arch rehabilitation in both jaws and (2) evaluate the patient's acceptance of this rehabilitation. Materials and Methods:, A 68-year-old patient scheduled for implant treatment was selected for an immediate implant loading protocol in both jaws. During two surgical events 3 weeks apart, eight maxillary and four mandibular Brånemark System® Mk IV TiUniteTM fixtures (Nobel Biocare AB, Göteborg, Sweden) were inserted and subsequently used to immediately support a cross-arch fixed prosthesis in the maxilla and a bar-retained overdenture in the mandible. Implant stability was recorded from the day of surgery periodically during a 1-year follow-up using resonance frequency analysis (RFA). Results:, At the 1-year follow-up, based on clinical, RFA, and radiographic evaluations, all implants and the reconstructions were classified as successful. All maxillary implants showed a decrease in the implant stability quotient (ISQ) value from the measurement at the time of surgery to the first follow-up, whereas two of four mandibular implants revealed an initial drop in stability. Irrespective of a specific ISQ level measured at implant surgery (ISQ range 53,74) and despite an initial decrease in stability, measurements recorded at the 12-month follow-up indicated similar stability levels for all maxillary implants (ISQ range 64,68) or the group of mandibular implants (ISQ range 72,75) but with a higher ISQ level for mandibular implants. Furthermore, the patient's acceptance of the immediate full-arch rehabilitation in both jaws was high. Conclusions:, The present case report demonstrates that a slightly staged approach for full-arch rehabilitation in both jaws using immediate implant loading protocols is a realistic treatment option. Furthermore, RFA follow-up indicates that immediately occlusally loaded implants placed in reduced bone quality and quantity are more prone to loose stability in the early healing period compared with implants placed in dense bone quality. [source] Fixed Mandibular Restorations on Three Early-Loaded Regular Platform Brånemark ImplantsCLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Issue 4 2001Hugo De Bruyn DDS ABSTRACT Background: Originally, the Brånemark System was used as a two-stage surgical procedure. Comparable clinical results have made one-stage and early-loading concepts possible alternatives in the edentulous mandible. From the patient's point of view, the financial aspect of implant treatment is important. In an attempt to decrease financial burden, the reduction of surgical interventions and reduction of the number of implants could be considered. Purpose: This prospective multicenter study evaluated (1) the 1-and 3-year success rates of implants loaded within 1 month after one-stage surgery with a fixed 10- to 12-unit bridge on three regular platform Brånemark System implants in the mandible, (2) the outcome of the prosthetic treatment, and (3) the opinion of patients regarding the treatment procedure. Materials and Methods: Of 20 patients, 19 received five implants in the mandible, of which three were functionally loaded with the one-stage technique (group 1). The loaded implants were inserted in a tripodal position, one implant in the symphysis and two located anterior of the mental foramen in the bicuspid area. Two additional implants were inserted for safety reasons but were not intended to be included in the restoration. These two additional implants served as either an unloaded one-stage control implant (group 2) or an unloaded control implant installed with the submerged technique (group 3). Immediately after surgery, the implants were loaded with a relined denture. The patients received a 10- to 12-unit prosthetic reconstruction an average 31 days (range, 4-53 d) after surgery. Implant stability was clinically checked at 3, 12, and 36 months. Radiographs were taken at corresponding follow-up visits to calculate bone-to-implant level and marginal bone resorption. Results: Six of 60 functionally loaded implants (10%) and 3 of 20 prostheses (15%) failed within the first year. The cumulative implant failure rate in group 1, both after 1 and after 3 years, was 9.5%. No implant failure occurred in the control groups 2 and 3. The average marginal bone level measured at 1 and 3 years was 1.6 mm (SD = 0.8 mm) and 2.1 mm (SD = 0.2 mm), respectively, for group 1; 1.5 mm (SD = 1.3 mm) and 2.4 mm (SD = 0.6 mm), respectively, for group 2; 0.8 mm (SD = 1.4 mm) and 0.7 mm (SD = 0.9 mm), respectively, for group 3. Conclusions: The results of treatment using three regular platform Brånemark System implants supporting a fixed mandibular arch reconstruction were less favorable than the outcome that can be expected with a standard four- to six-implant with one-stage surgery. [source] Effects of Implant Design and Surface on Bone Regeneration and Implant Stability: An Experimental Study in the Dog MandibleCLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Issue 1 2001Lars Rasmusson DMD ABSTRACT Background: Previous experimental studies have shown a higher degree of bone-implant contact for surface-enlarged implants compared with machined implants. Yet, there is insufficient evidence that such implants show higher stability and an increased survival rate. Purpose: The purpose of this investigation was to study the integration and stability of grit-blasted implants with retention elements on the implant neck, with and without marginal bone defects, compared with machined implants without retention elements. Materials and Methods: After tooth extraction of the mandibular premolars in six dogs, two grit-blasted, partly microthreaded Astra Tech implants and one standard Branemark implant were bilaterally placed in each dog. On one side, 3 ± 3 mm large buccal defects were created, to expose three to four implant threads. The contralateral side served as control, and no defects were made. The animals were sacrificed after 4 months of healing. Implant stability was measured using resonance frequency analysis at implant installation and after 4 months of healing. Histologic and histomorpho-metric evaluation was made after 4 months of healing. Results: Resonance frequency analysis indicated that all implants in the test and control groups were osseointegrated after 4 months, with a tendency toward higher implant stability for the Astra Tech implants. There was a statistically significant higher increase in resonance frequency for the Astra test implants compared with their corresponding controls. Histology and histomorphometry showed well-integrated implants with varying degrees of bone repair at the defect sites. The greater bone-implant contact for the Astra implants was statistically significant. No significant difference between the implants in amount of bone filling the threads was recorded. Conclusions: The Astra Tech implants tested showed a higher degree of bone,implant contact and higher level of bone regenerated at defect sites compared with the Brånemark implants. Resonance frequency analysis demonstrated a significantly higher increase in the Astra test implants compared with their control groups than did the Brånemark test implants versus their controls. [source] Resonance frequency measurements in vivo and related surface properties of magnesium-incorporated, micropatterned and magnesium-incorporated TiUnite®, Osseotite®, SLA® and TiOblast® implantsCLINICAL ORAL IMPLANTS RESEARCH, Issue 10 2009Young-Taeg Sul Abstract Objective: To investigate implant stability using resonance frequency measurements of topographically changed and/or surface chemistry-modified implants in rabbit bone. Material and methods: Six groups of microstructured, screw-shaped titanium implants: two oxidized, cation-incorporated experimental implants [Mg implants and MgMp implants with micropatterned thread flanges (80,150 ,m wide and 60,70 ,m deep)] and four commercially available clinical implants (TiUnite®, Osseotite®, SLA®, and TiOblast®) were installed in 10 rabbit tibia for 6 weeks. The surface properties of the implants were characterized in detail using several analytical techniques. Implant stability was measured using a resonance frequency analyzer (OsstellÔ). Results: Surface characterization of the implants revealed microstructured, moderately rough implant surfaces varying 0.7,1.4 ,m in Sa (mean height deviation), but with clear differences in surface chemistry. After 6 weeks, all implants showed statistically significantly higher increases in implant stability. When compared with one another, MgMp implants showed the most significant mean implant stability quotient (ISQ) value relative to the others (P,0.016). In terms of increment (,ISQ) in implant stability, MgMp implants showed a significantly greater value as compared with Osseotite® (P,0.005), TiOblast® (P,0.005), TiUnite® (P,0.005), SLA® (P,0.007), and Mg implants (P,0.012). In addition, transducer direction dependence of resonance frequency analysis (RFA) measurements was observed such that the differences in the mean ISQ values between longitudinal and perpendicular measurements were significant at implant placement (P,0.004) and after 6 weeks (P,0). Conclusion: The present study found that implant surface properties influence RFA measurements of implant stability. Surface chemistry-modified titanium implants showed higher mean ISQ values than did topographically changed implants. In particular, cation (magnesium)-incorporated micropatterns in MgMp implants may play a primary role in ,ISQ. [source] Implant stability during osseointegration in irradiated and non-irradiated minipig alveolar bone: an experimental studyCLINICAL ORAL IMPLANTS RESEARCH, Issue 2 2008Henk W. D. Verdonck Abstract: Objectives: Primary implant stability is related to local bone density. After insertion of an implant, implant stability is subject to changes due to bone remodeling. In patients who have undergone radiotherapy in the head and neck region, implant stability is impaired because irradiation reduces bone vitality. The current study was designed to monitor and test implant stability immediately after implant placement and during osseointegration in irradiated and non-irradiated minipig alveolar bone. Materials and methods: All maxillary and mandibular premolars and molars of six adult Göttingen minipigs were extracted. The maxilla and mandible of three minipigs received three irradiation exposures at a total dose of 24 Gy. After irradiation, five initial implant holes were drilled in the residual alveolar ridge of each edentulous site. In order to assess bone vascularity, laser Doppler flowmetry recordings were carried out in the initial holes. A total of 120 implants were placed in the six minipigs. Subsequently, and at 8, 16, and 24 weeks after implant placement, implant stability was recorded by resonance frequency analysis (RFA). RFA values were expressed as an implant stability quotient (ISQ). Results: ISQ values recorded immediately after implant placement showed no differences between irradiated and non-irradiated minipigs. Repeated measurements at the four recording moments showed a decrease of ISQ values in all minipigs, being more pronounced in irradiated bone, when compared with non-irradiated bone. The results at the third and fourth recording moments showed a stabilization or even a slight increase of ISQ values. Conclusions: The results document the negative effect of irradiation on bone vascularity and hence on implant stability. [source] The characterization and optimization of injectable silicone resin particles in conjunction with dermal fibroblasts and growth factors: An in vitro studyJOURNAL OF BIOMEDICAL MATERIALS RESEARCH, Issue 1 2010Robert M. Crews Abstract Minimally invasive subdermal injection of liquid silicone has been used clinically to augment the soft tissue of the foot to mitigate high pressures that cause diabetic foot ulcers. However, implant migration has been a clinical issue. The objective of this study was to assess the effects of three specific concentrations of silicone resin particles (12 ,m average diameter) in conjunction with either platelet-derived growth factor (PDGF-BB) or basic fibroblast growth factor (bFGF) on fibroblast cell proliferation, collagen synthesis, cell morphology, and migration through in vitro assays and a monolayer scratch wound model. PDGF and bFGF enhanced the proliferation of fibroblasts 5.7-fold and fivefold, respectively, while the addition of silicone particles had no significant effect on proliferation. Collagen production was increased approximately twofold with the addition of bFGF and the medium concentration of particles over bFGF without particles and the PDGF groups. The addition of silicone particles had no significant effect on collagen production compared with control groups without particles. Fibroblast migration was enhanced by the addition of both PDGF and bFGF compared to controls, although slower scratch wound closure rates were observed in the presence of particles compared to controls without particles. Cell morphology suggested that particles induced cellular aggregation encircling silicone particles postwounding as well as migration into the wound area. These results suggest that silicone particles in combination with a growth factor might enhance fibroblast aggregation and implant stability, and could promote connective tissue ingrowth and implant encapsulation in the soft tissue of the diabetic foot. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2010 [source] Increased bone formation around coated implantsJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 8 2009Bernd Stadlinger Abstract Aim: We hypothesized that coating threaded, sandblasted acid-etched titanium implants with collagen and chondroitin sulphate (CS) increases bone formation and implant stability, compared with uncoated controls. Materials and Methods: Three different implant surface conditions were applied: (1) sandblasted acid-etched (control), (2) collagen/chondroitin sulphate (low-dose , CS1), (3) collagen/chondroitin sulphate (high-dose , CS2). Sixty 9.5 mm experimental implants were placed in the mandible of 20 minipigs. Bone,implant contact (BIC) and relative peri-implant bone-volume density (rBVD , relation to bone-volume density of the host bone) were assessed after 1 and 2 months of submerged healing. Implant stability was measured by resonance frequency analysis (RFA). Results: After 1 month, coated implants had significantly more BIC compared with controls (CS1: 68%, p<0.0001, CS2: 63%, p=0.009, control: 52%). The rBVD was lower for all surface conditions, compared with the hostbone. After 2 months, BIC increased for all surfaces. No significant differences were measured (CS1: 71%, p=0.016, CS2: 68%, p=0.67, control: 63%). The rBVD was increased for coated implants. RFA values were 71,77 at implantation, 67,73 after 1 month and 74,75 after 2 months. Differences in rBVD and RFA were not statistically significant. Conclusions: Data analysis suggests that collagen/CS has a positive influence on bone formation after 1 month of endosseous healing. [source] A biomechanical assessment of the relation between the oral implant stability at insertion and subjective bone quality assessmentJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 4 2007Ghada Alsaadi Abstract Aim: The study was set to evaluate the validity of subjective jaw bone quality assessment. Materials and Methods: A total of 298 patients (198 females, mean age 56.4) were treated with oral implants at the Periodontology Department at the University Hospital of KUL. A total of 761 TiUniteÔ implants have been installed. Subjective bone quality assessment was performed on radiographs and by the surgeon's tactile sensation and was compared with torque measurements. In a subset of patients, implant stability was also assessed by implant stability quotient and/or periotest values. Results: Subjective assessment of bone quality was related to the PTV, ISQ and placement torque [in the crestal, the second and the apical third (N cm)], respectively; in grade 1: ,5.3, 73.3 (4.2, 9.6, 15.2), and grade 3 or 4: ,1.6, 55 (3.3, 5.5, 8.4). For the surgeon's tactile sensation, a good correlation was noted for the presence of a thick cortex: ,4.6, 70.3 (4.2, 9.7, 15.1), or a thin one: ,0.3, 65.9 (3.6, 6.9, 10.1). For dense trabecular bone, the values were ,2.8, 69.4 (4.4, 9.7,14.8), while for poor trabecular bone, the values were,1.7, 66.4 (3.6, 6.4, 9.8). Conclusions: Subjective assessment of bone quality is related to PTV, ISQ and placement torque measurements at implant insertion. [source] Analysis of the possibility of the relationship between various implant-related measures: an 18-month follow-up studyJOURNAL OF ORAL REHABILITATION, Issue 2 2008T. F. TÖZÜM Summary, Better clarification of the long-term relationship among the various implant-related measures could improve the evaluation process for dental implants. Thus, the aim of the present study was to determine the potential correlations among the volumetric features and nitric oxide content of peri-implant sulcus fluid (PISF) and measures of implant stability, and the marginal bone loss. Completely edentulous patients (n = 15) treated with dental implants and ball attachment mandibular over dentures were included. Resonance frequency analysis (RFA), marginal bone level measurements, PISF volume and spectrophotometrically determined nitrite levels were recorded for all dental implant sites. Measures for early (n = 16) and delayed (n = 14) loaded dental implants were comparatively analysed for a period of 18 months. Some random correlations between PISF volume and marginal bone level, PISF nitrite level and marginal bone level and PISF volume and PISF nitrite content, and RFA and PISF volume were observed. However, the only constant correlation was noticed between implant stability (RFA scores) and marginal bone level. This correlation was negative and significant for all dental implants and for delayed loaded implants (P < 0·05). The pattern of loading seemed to affect the extent, but not the pattern of this relationship. While some of the implant-related measures may be strongly associated (e.g. dental implant stability and marginal bone level), not all measures from a single implant site are likely to be related. Such associations may be under the influence of a variety of factors including the loading protocol of dental implants. [source] Assessment of correlation between computerized tomography values of the bone, and maximum torque and resonance frequency values at dental implant placementJOURNAL OF ORAL REHABILITATION, Issue 12 2006I. TURKYILMAZ summary, The aim of this study was to determine the bone density in the designated implant sites using computerized tomography (CT), the fastening torque values of dental implants, and the implant stability values using resonance frequency analysis. Further aim was to evaluate a possible correlation between bone density, fastening torque and implant stability. Eighty-five patients were treated with 158 Brånemark System implants. CT machine was used for preoperative evaluation of the jawbone for each patient, and bone densities were recorded in Hounsfield units (HU). The fastening torque values of all implants were recorded with the OsseoCare equipment. Implant stability measurements were performed with the Osstell machine. The average bone density and fastening torque values were 751·4 ± 256 HU and 39·7 ± 7 Ncm for 158 implants. The average primary implant stability was 73·2 ± 6 ISQ for seventy implants. Strong correlations were observed between the bone density, fastening torque and implant stability values of Brånemark System TiUnite MKIII implants at implant placement (P < 0·001). These results strengthen the hypothesis that it may be possible to predict and quantify initial implant stability and bone quality from pre-surgical CT diagnosis. [source] Safety of, and biological and functional response to, a novel metallic implant for the management of focal full-thickness cartilage defects: Preliminary assessment in an animal model out to 1 yearJOURNAL OF ORTHOPAEDIC RESEARCH, Issue 5 2006Carl A. Kirker-Head Abstract Focal full-thickness cartilage lesions of the human medial femoral condyle (MFC) can cause pain and functional impairment. Affected middle-aged patients respond unpredictably to existing treatments and knee arthroplasty may be required, prompting risk of revision. This study assesses the safety of, and biological and functional response to, a metallic resurfacing implant which may delay or obviate the need for traditional arthroplasty. The anatomic contour of the surgically exposed MFC of six adult goats was digitally mapped and an 11 mm diameter full-thickness osteochondral defect was created. An anchor-based Co,Cr resurfacing implant, matching the mapped articular contour, was implanted. Each goat's contralateral unoperated femorotibial joint was used as a control. Postoperative outcome was assessed by lameness examination, radiography, arthroscopy, synoviocentesis, necropsy, and histology up to 26 (n,=,3) or 52 (n,=,3) weeks. By postoperative week (POW) 4, goats demonstrated normal range of motion, no joint effusion, and only mild lameness in the operated limb. By POW 26 the animals were sound with only occasional very mild lameness. Arthroscopy at POW 14 revealed moderate synovial inflammation and a chondral membrane extending centrally across the implant surface. Radiographs at POWs 14 to 52 implied implant stability in the operated joints, as well as subchondral bone remodeling and mild exostosis formation in the operated and contralateral unoperated joints of some goats. By POW 26, histology revealed new trabecular bone abutting the implant. At POWs 26 and 52 MFC cartilage was metachromatic and intact in the operated and unoperated femorotibial joints. Proximal tibiae of some operated and unoperated limbs demonstrated limited subchondral bone remodeling and foci of articular cartilage fibrillation and thinning. The chondral membrane crossing the prosthesis possessed a metachromatic matrix containing singular and clustered chondrocytes. Our data imply the safety, biocompatibility, and functionality of the implant. Focal articular damage was documented in the operated joints at POWs 26 and 52, but lesions were much reduced over those previously reported in untreated defects. Expanded animal or preclinical human studies are justified. © 2006 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res [source] Early Complete Failures of Fixed Implant-Supported Prostheses in the Edentulous Maxilla: A 3-Year Analysis of 17 Consecutive Cluster Failure PatientsCLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Issue 2 2006Odont Dr/PhD, Torsten Jemt DDS ABSTRACT Background, Clusters of implant failures in the edentulous maxilla seem to occur in some patients. To create groups for analysis with higher numbers of these patients implies large original groups for inclusion. Purpose, The aim of this study was to retrospectively describe and compare a group of "cluster failure patients" with randomly selected patients treated in the edentulous maxilla. Materials and Methods, From a group of 1,267 consecutively treated patients in one clinic, all patients presenting failing fixed implant-supported prostheses within the first 3 years of follow-up were included. All patients were treated with turned titanium implants using two-stage surgery. A control group of equal number of patients were created for comparison. Data on patients were retrospectively retrieved from their records, and compared. Results, Seventeen patients (1.3%) met the inclusion criteria in the entire group. The bone resorption index revealed less bone quantity in the study group (p < .05) during implant placement, but there was no difference regarding primary implant stability at first-stage surgery. The distribution of short and long implants showed relatively higher number of short implants in the study group (p < .05), and more patients had a presurgical discussion on the risk of implant failure prior to treatment in this group (p < .05). Only 5 out of 102 implants (4.9%) were lost before prosthesis placement as compared to 38 and 25 lost implants during the following two years in the study group. Smoking habits and signs of bone loss related to periodontitis in the lower dentition were more frequent in the study group, but did not reach a significant level (p > .05). Conclusion, The results indicate that bone quantity, reflected in fixture length, has a significant impact on increased implant failure risk. Other factors of interest as predictors for implant failures could be smoking habits and also possibly signs of periodontitis in the opposing dentition. [source] Bone Reformation and Implant Integration following Maxillary Sinus Membrane Elevation: An Experimental Study in PrimatesCLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Issue 1 2006Vinicius C Palma DDS ABSTRACT Background:, Recent clinical studies have described maxillary sinus floor augmentation by simply elevating the maxillary sinus membrane without the use of adjunctive grafting materials. Purpose:, This experimental study aimed at comparing the histologic outcomes of sinus membrane elevation and simultaneous placement of implants with and without adjunctive autogenous bone grafts. The purpose was also to investigate the role played by the implant surface in osseointegration under such circumstances. Materials and Methods:, Four tufted capuchin primates had all upper premolars and the first molar extracted bilaterally. Four months later, the animals underwent maxillary sinus membrane elevation surgery using a replaceable bone window technique. The schneiderian membrane was kept elevated by insertion of two implants (turned and oxidized, Brånemark System®, Nobel Biocare AB, Göteborg, Sweden) in both sinuses. The right sinus was left with no additional treatment, whereas the left sinus was filled with autogenous bone graft. Implant stability was assessed through resonance frequency analysis (OsstellTM, Integration Diagnostics AB, Göteborg, Sweden) at installation and at sacrifice. The pattern of bone formation in the experimental sites and related to the different implant surfaces was investigated using fluorochromes. The animals were sacrificed 6 months after the maxillary sinus floor augmentation procedure for histology and histomorphometry (bone-implant contact, bone area in threads, and bone area in rectangle). Results:, The results showed no differences between membrane-elevated and grafted sites regarding implant stability, bone-implant contacts, and bone area within and outside implant threads. The oxidized implants exhibited improved integration compared with turned ones as higher values of bone-implant contact and bone area within threads were observed. Conclusions:, The amount of augmented bone tissue in the maxillary sinus after sinus membrane elevation with or without adjunctive autogenous bone grafts does not differ after 6 months of healing. New bone is frequently deposited in contact with the schneiderian membrane in coagulum-alone sites, indicating the osteoinductive potential of the membrane. Oxidized implants show a stronger bone tissue response than turned implants in sinus floor augmentation procedures. [source] Implant Stability during Initiation and Resolution of Experimental Periimplantitis: An Experimental Study in the DogCLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Issue 3 2005Lars Sennerby DDS ABSTRACT Background: Histologic studies have demonstrated the possibility to reestablish direct bone-implant contacts after ligature-induced periimplantitis. The influence of the reosseointegration on the stability of implants is not known. Purpose: The aim of the present investigation was to study bone tissue and associated implant stability alterations that occurred during induction and resolution of periimplantitis using resonance frequency analysis (RFA), radiography, and histology. Materials and Methods: Three implants with smooth (turned) or roughened (SLA®) surfaces were placed in each side of the edentulous mandible of four dogs. Experimental periimplantitis was induced for 3 months. Five weeks later, the animals were treated with antibiotics and surgical therapy and were followed for another 6 months. Periapical radiographs and RFA were used to evaluate marginal bone levels and implant stability throughout the study period. After termination, the tissue-implant interface was evaluated by light microscopy in ground sections. Results: There was a linear relationship between radiographic and RFA findings because continuous loss of marginal bone and a decrease in implant stability were observed for both implant surfaces during the periimplantitis period. Antibiotic treatment and surgical therapy resulted in some reosseointegration, which was more marked for the SLA surface. The resonance frequency values corresponded well to the histometric measurements because reosseointegration resulted in an increase in implant stability. Conclusions: The findings from the present study indicate a linear relationship between marginal bone level and resonance frequency value. It is suggested that the RFA technique is sensitive and may be used to detect even a minor change in the level of bone-implant contact. [source] Short Implants in the Severely Resorbed Maxilla: A 2-Year Retrospective Clinical StudyCLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Issue 2005Franck Renouard DDS ABSTRACT Background: Although the predictability of endosseous dental implants is well documented, the restoration of the posterior region of the maxilla remains a challenge. The placement of short implants is one therapeutic option that reduces the need for augmentation therapy. Purpose: The purpose of this retrospective study was to assess the survival rates of 6 to 8.5 mm-long implants in the severely resorbed maxilla following a surgical protocol for optimized initial implant stability. Materials and Methods: The study included 85 patients with 96 short (6,8.5 mm) implants (Brånemark System®, Nobel Biocare AB, Göteborg, Sweden) supporting single-tooth and partial reconstructions. The implants had a machined (54) or an oxidized (TiUniteÔ, Nobel Biocare AB) (42) surface. A one-stage surgical protocol with delayed loading was used. The patients were followed for at least 2 years after loading (average follow-up period 37.6 months). The marginal bone resorption was assessed by radiographic readings. Results: Five implants were lost during the first 9 months, and four implants were lost to follow-up. The cumulative survival rate was 94.6%. Four of the failed implants had a machined surface, and one had an oxidized surface. The mean marginal bone resorption after 2 years in function was 0.44 ± 0.52 mm. Conclusion: This study demonstrates that the use of short implants maybe considered for prosthetic rehabilitation of the severely resorbed maxilla as an alternative to more complicated surgical techniques. [source] Bone Formation at Titanium Implants Prepared with Iso- and Anisotropic Surfaces of Similar Roughness: An in Vivo StudyCLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Issue 1 2005Anna Göransson DDS ABSTRACT Background: Implant surface topography influences the bone response after implantation. However, the importance of surface orientation is not known. Purpose: The aim of this study was to investigate the bone tissue response and the stability of titanium implants prepared with isotropic and anisotropic surfaces of similar roughness. Materials and Methods: A total of 18 implants were divided into two groups and were inserted into the femurs of nine rabbits for 12 weeks. Confocal laser scanning microscopy was used for the topographic description to verify that the two different surfaces were modified as intended. The stability of the implants was recorded by resonance frequency (RF) measurements at insertion and at time of removal, after which the implants were evaluated histomorphometrically. Results: RF measurements showed that implant stability increased with time. However, there was no significant difference between the two different surface modifications at insertion and after 12 weeks. The histomorphometric comparison revealed no statistically significant differences in regard to either bone-to-metal contact or bone area inside the threads. Conclusion: Titanium implants prepared with isotropic and anisotropic surfaces of similar roughness integrate similarly to bone during the 3 months after implantation. [source] Stability Measurements of Osseointegrated Implants Using Osstell in Partially Edentulous Jaws after 1 Year of Loading: A Pilot StudyCLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Issue 3 2002Piero Balleri MD ABSTRACT Background: The introduction of resonance frequency analysis (RFA) as a commercially available technique has made it possible to measure implant stability in implant stability quotient (ISQ) units at any time during the course of implant treatment and loading. However, no information on normal ISQ levels can be found in the literature. Purpose: The aim of this pilot study was to measure the stability of clinically successful implants in partially edentulous patients after 1 year of loading and to study the influence of jaw, anterior/posterior position, implant length, and marginal bone level on implant stability. Materials and Methods: Fourteen partially edentulous patients previously treated with 45 implants were subjected to clinical and radiographie evaluations and RFA measurements using Osstell (Integration Diagnostics, Sävedalen, Sweden) after 1 year of loading. Results: All 45 implants were stable, and implant stability levels were in the range of 57 to 82 ISQ units with a mean of 69 ± 6.5 ISQ after 1 year of loading. Mandibular implants were more stable than were maxillary ones. There were no differences between anterior and posterior implants. No correlation could be found between implant length and stability. Only minor marginal bone resorption was observed. Conclusions: The results from this limited material showed that successfully integrated implants have ISQ levels from 57 to 82 ISQ with a mean of 69 ISQ after 1 year of loading. Mandibular implants are more stable than are maxillary ones. High implant stability can be achieved with short implants and placement in posterior regions. [source] Influence of surgical technique and surface roughness on the primary stability of an implant in artificial bone with different cortical thickness: a laboratory studyCLINICAL ORAL IMPLANTS RESEARCH, Issue 2 2010Afsheen Tabassum Abstract Objective: The aim of this biomechanical study was to assess the interrelated effect of both surface roughness and surgical technique on the primary stability of dental implants. Material and methods: For the experiment, 160 screw-designed implants (Biocomp®), with either a machined or an etched surface topography, were inserted into polyurethane foam blocks (Sawbones®). As an equivalent of trabecular bone, a density of 0.48 g/cm3 was chosen. To mimic the cortical layer, on top of these blocks short-fibre-filled epoxy sheets were attached with a thickness varying from 0 to 2.5 mm. The implant sites were prepared using either a press-fit or an undersized technique. To measure the primary stability of the implant, both the insertion and the removal torques were scored. Results: Independent of the surgical technique used, both implant types showed an increased insertion and removal torque values with increasing cortical thickness, although >2 mm cortical layer no further increase in insertion torque was observed. In the models with only trabecular bone (without cortical layer) and with a 1 mm cortical layer, both implant types showed a statistically higher insertion and removal torque values for undersized compared with the press-fit technique. In addition, etched implants showed a statistically higher insertion and removal torque mean values compared with machined implants. In the models with 2 and 2.5 mm cortical layers, with respect to the insertion torque values, no effect of either implantation technique or implant surface topography could be observed. Conclusion: The placement of etched implants in synthetic bone models using an undersized preparation technique resulted in enhanced primary implant stability. A correlation was found between the primary stability and the cortical thickness. However, at or above a cortical thickness of 2 mm, the effect of both an undersized surgical approach, as also the presence of a roughened (etched) implant surface, had no extra effect. Besides the mechanical aspects, the biological effect of undersized drilling, i.e. the bone response on the extra insertion torque forces should also be elucidated. Therefore, additional in vivo studies are needed. To cite this article: Tabassum A, Meijer GJ, Wolke JGC, Jansen JA. Influence of surgical technique and surface roughness on the primary stability of an implant in artificial bone with different cortical thickness: a laboratory study. Clin. Oral Impl. Res. 21, 2010; 213,220. doi: 10.1111/j.1600-0501.2009.01823.x [source] Resonance frequency measurements in vivo and related surface properties of magnesium-incorporated, micropatterned and magnesium-incorporated TiUnite®, Osseotite®, SLA® and TiOblast® implantsCLINICAL ORAL IMPLANTS RESEARCH, Issue 10 2009Young-Taeg Sul Abstract Objective: To investigate implant stability using resonance frequency measurements of topographically changed and/or surface chemistry-modified implants in rabbit bone. Material and methods: Six groups of microstructured, screw-shaped titanium implants: two oxidized, cation-incorporated experimental implants [Mg implants and MgMp implants with micropatterned thread flanges (80,150 ,m wide and 60,70 ,m deep)] and four commercially available clinical implants (TiUnite®, Osseotite®, SLA®, and TiOblast®) were installed in 10 rabbit tibia for 6 weeks. The surface properties of the implants were characterized in detail using several analytical techniques. Implant stability was measured using a resonance frequency analyzer (OsstellÔ). Results: Surface characterization of the implants revealed microstructured, moderately rough implant surfaces varying 0.7,1.4 ,m in Sa (mean height deviation), but with clear differences in surface chemistry. After 6 weeks, all implants showed statistically significantly higher increases in implant stability. When compared with one another, MgMp implants showed the most significant mean implant stability quotient (ISQ) value relative to the others (P,0.016). In terms of increment (,ISQ) in implant stability, MgMp implants showed a significantly greater value as compared with Osseotite® (P,0.005), TiOblast® (P,0.005), TiUnite® (P,0.005), SLA® (P,0.007), and Mg implants (P,0.012). In addition, transducer direction dependence of resonance frequency analysis (RFA) measurements was observed such that the differences in the mean ISQ values between longitudinal and perpendicular measurements were significant at implant placement (P,0.004) and after 6 weeks (P,0). Conclusion: The present study found that implant surface properties influence RFA measurements of implant stability. Surface chemistry-modified titanium implants showed higher mean ISQ values than did topographically changed implants. In particular, cation (magnesium)-incorporated micropatterns in MgMp implants may play a primary role in ,ISQ. [source] In-patient comparison of immediate and conventional loaded implants in mandibular molar sites within 12 monthsCLINICAL ORAL IMPLANTS RESEARCH, Issue 4 2008Güncü, M. Bar Abstract Objectives: The aim of this prospective clinical study was to evaluate the clinical outcomes of dental implants placed in the mandibular molar sites and immediately functionally restored compared with conventionally loaded controls in an in-patient study. Material and methods: Twenty-four dental implants were placed in 12 patients who had first molar loss bilaterally in the mandibular area. One site of the patient was determined as immediately loaded (IL) and the other side was conventionally loaded (CL). Resonance frequency analyses for implant stability measurements, radiographic examinations for marginal bone levels and peri-implant evaluations were performed during the clinical follow-up appointments within 12 months. Results: During the 12-month follow-up period, only one implant was lost in the IL group. The mean implant stability quotient values were 74.18±5.72 and 75.18±3.51 for Groups IL and CL at surgery, respectively, and the corresponding values were 75.36±5.88 and 75.64±4.84 at 1-year recall, respectively. The difference was not statistically significant between the two groups during the 12-month study period (P>0.05). When peri-implant parameters were evaluated, excellent peri-implant health was demonstrated during the 1-year observation period and all implants showed less than 1 mm of marginal bone resorption during the first year. Conclusions: In the present study, immediate functionally loading did not negatively affect implant stability, marginal bone levels and peri-implant health when compared with conventional loading of single-tooth implants. [source] Implant stability during osseointegration in irradiated and non-irradiated minipig alveolar bone: an experimental studyCLINICAL ORAL IMPLANTS RESEARCH, Issue 2 2008Henk W. D. Verdonck Abstract: Objectives: Primary implant stability is related to local bone density. After insertion of an implant, implant stability is subject to changes due to bone remodeling. In patients who have undergone radiotherapy in the head and neck region, implant stability is impaired because irradiation reduces bone vitality. The current study was designed to monitor and test implant stability immediately after implant placement and during osseointegration in irradiated and non-irradiated minipig alveolar bone. Materials and methods: All maxillary and mandibular premolars and molars of six adult Göttingen minipigs were extracted. The maxilla and mandible of three minipigs received three irradiation exposures at a total dose of 24 Gy. After irradiation, five initial implant holes were drilled in the residual alveolar ridge of each edentulous site. In order to assess bone vascularity, laser Doppler flowmetry recordings were carried out in the initial holes. A total of 120 implants were placed in the six minipigs. Subsequently, and at 8, 16, and 24 weeks after implant placement, implant stability was recorded by resonance frequency analysis (RFA). RFA values were expressed as an implant stability quotient (ISQ). Results: ISQ values recorded immediately after implant placement showed no differences between irradiated and non-irradiated minipigs. Repeated measurements at the four recording moments showed a decrease of ISQ values in all minipigs, being more pronounced in irradiated bone, when compared with non-irradiated bone. The results at the third and fourth recording moments showed a stabilization or even a slight increase of ISQ values. Conclusions: The results document the negative effect of irradiation on bone vascularity and hence on implant stability. [source] Relevance of resonance frequency analysis to evaluate dental implant stability: simulation and histomorphometrical animal experimentsCLINICAL ORAL IMPLANTS RESEARCH, Issue 1 2008Yoshihiro Ito Abstract Background: Resonance frequency analysis (RFA) is applied to evaluate implant stability, and the clinical relevance of this application is accepted. However, a discrepancy between resonance frequency (RF) and other parameters of implant stability such as implant insertion torque and bone mineral density at the insertion site has been reported. In addition, the relation between RF and histological implant,bone contact has not been well documented. Purpose: To explain this discrepancy and to clarify the relation between RF and histological implant,bone contact, we conducted the present study. Materials and methods: A hydroxyapatite-coated implant, 4 mm diameter and 10 mm length, was used. We placed the implant in a small plastic box vertically and fixed the implant in the box with small screws at different height positions. An ,Osstell' transducer was mounted on the implant and RF was measured with or without loosening the screws. Twenty-four implants were placed in the tibiae of four mini-pigs. The animals were sacrificed 1, 2 and 4 weeks after the placement, and the RF of each implant was measured. Ground sections were prepared and implant,bone contact was histomophometrically measured. Results: Loosening the screw at the neck region of the implant remarkably decreased RF compared with the screws of the other regions. Correlation between RF and implant,bone contact, which was measured all around the implant, was not significant (r=0.221, P=0.299). However, the correlation coefficient increased to ,0.361' when implant,bone contact was measured at the neck of the implant (P=0.0835), although these two parameters were not statistically correlated. Conclusions: Although RF did not correlate with histological implant,bone contact, the present results demonstrated that a connection between the implant and bone at the neck region of the implant affects RF the most effectively, further suggesting the superiority of RFA in the process of implant treatment and the follow-up. The present results could explain the discrepancy between RFA and other parameters of implant stability. [source] Resonance frequency analysis in relation to jawbone characteristics and during early healing of implant installationCLINICAL ORAL IMPLANTS RESEARCH, Issue 3 2007M. A. Huwiler Objectives: To monitor resonance frequency analysis (RFA) in relation to the jawbone characteristics and during the early phases of healing and incorporation of Straumann® dental implants with an SLA surface. Material and methods: 17 Straumann 4.1 mm implants (10 mm) and 7 Straumann 4.8 mm implants (10 mm) were installed and ISQ determined at baseline and after 1, 2, 3, 4, 5, 6, 8 and 12 weeks. Central bone cores were analyzed from the 4.1 mm implants using micro CT for bone volume density (BVD) and bone trabecular connectivity (BTC). Results: Pocket probing depths ranged from 2,4 mm and bleeding on probing from 5,20%. At baseline, BVD varied between 24% and 65% and BTC between 4.9 and 25.4 for the 4.1 mm implants. Baseline ISQ varied between 55 and 74 with a mean of 61.4. No significant correlations were found between BVD or BTC and ISQ Values. For the 4.8 mm diameter implants baseline ISQ values ranged from 57,70 with a mean of 63.3. Over the healing period ISQ values increased at 1 week and decreased after 2,3 weeks. After 4 weeks ISQ values, again increased slightly, no significant differences were noted over time. One implant (4.1 mm) lost stability at 3 weeks. Its ISQ value had dropped from 68 to 45. However the latter value was determined after the clinical diagnosis of instability. Conclusion: ISQ values of 57,70 represented homeostasis and implant stability. However no predictive value for loosing implant stability can be attributed to RFA since the decrease occurred after the fact. [source] Validity and clinical significance of biomechanical testing of implant/bone interfaceCLINICAL ORAL IMPLANTS RESEARCH, Issue S2 2006Carlos Aparicio Abstract Purpose: The aim of this paper was to review the clinical literature on the Resonance frequency analysis (RFA) and Periotest techniques in order to assess the validity and prognostic value of each technique to detect implants at risk for failure. Material and methods: A search was made using the PubMed database to find clinical studies using the RFA and/or Periotest techniques. Results: A limited number of clinical reports were found. No randomized-controlled clinical trials or prospective cohort studies could be found for validity testing of the techniques. Consequently, only a narrative review was prepared to cover general aspects of the techniques, factors influencing measurements and the clinical relevance of the techniques. Conclusions: Factors such as bone density, upper or lower jaw, abutment length and supracrestal implant length seem to influence both RFA and Periotest measurements. Data suggest that high RFA and low Periotest values indicate successfully integrated implants and that low/decreasing RFA and high/increasing Periotest values may be signs of ongoing disintegration and/or marginal bone loss. However, single readings using any of the techniques are of limited clinical value. The prognostic value of the RFA and Periotest techniques in predicting loss of implant stability has yet to be established in prospective clinical studies. [source] Significance of primary stability for osseointegration of dental implantsCLINICAL ORAL IMPLANTS RESEARCH, Issue 3 2006Natalia Lioubavina-Hack Abstract Aim: To investigate the significance of the initial stability of dental implants for the establishment of osseointegration in an experimental capsule model for bone augmentation. Material and methods: Sixteen male rats were used in the study. In each rat, muscle-periosteal flaps were elevated on the lateral aspect of the mandibular ramus on both sides, resulting in exposure of the bone surface. Small perforations were then produced in the ramus. A rigid, hemispherical Teflon® capsule with a diameter of 6 mm and a height of 4 mm and with a hole in its middle portion, prepared to fit the circumference of an ITI® HC titanium implant of 2.8 mm in diameter, was fixed to the ramus using 4 mini-screws. On one side of the jaw, the implant was placed through the hole in such a way that its apex did not make contact with the mandibular ramus (test). This placement of the implant did not ensure primary stability. On the other side of the jaw, a similar implant was placed through the hole of the capsule in such a way that contact was made between the implant and the surface of the ramus (control). This provided primary stability of the implant. After placement of the implants, the soft tissues were repositioned over the capsules and sutured. After 1, 3, 6 and 9 months, four animals were sacrificed and subjected to histometric analysis. Results: The mean height of direct bone-to-implant contact of implants with primary stability was 38.8%, 52.9%, 64.6% and 81.3% of the implant length at 1, 3, 6 and 9 months, respectively. Of the bone adjacent to the implant surface, 28.1%, 28.9%, 52.6% and 69.6%, respectively, consisted of mineralized bone. At the test implants, no bone-to-implant contact was observed at any observation time or in any of these non-stabilized specimens. Conclusion: The findings of the present study indicate that primary implant stability is a prerequisite for successful osseointegration, and that implant instability results in fibrous encapsulation, thus confirming previously made clinical observations. [source] Positive effect of early loading on implant stability in the bi-cortical guinea-pig modelCLINICAL ORAL IMPLANTS RESEARCH, Issue 4 2005Els De Smet Abstract: Loading, early after implant placement, has gained rapid interest in dentistry. Primary implant stability, as e.g. defined by resonance frequency instrumentation, has been isolated as a predicator when immediate and early implant loading is applied. The aim of this study was to investigate the effect of early (after 7 days) mechanical loading on the establishment of osseointegration by means of resonance frequency analysis (RFA). Percutaneous titanium implants were installed in both tibiae of 10 guinea-pigs. One week after implant installation, one implant (test) was loaded daily for 6 weeks, while the contra-lateral served as the unloaded one (control). A sinusoidally varying bending moment was applied at a frequency of 3 Hz and a force amplitude of 5 N, for 1800 cycli. Resonance frequency was measured at implant installation and from then on weekly using the RFA-device (Osstell®). Contrary to control implants, that showed a decrease in stability 1 week after installation, reaching a minimum at 3 weeks (,200 Hz), test implants showed a progressive increase in stability over time. After 6 weeks, the mean resonance frequency of test and control implants reached the same values. As confirmed by recent literature, early loading does not have to endanger the establishment of osseointegration of titanium implants. On the contrary, controlled loading is beneficial to maintain the implant stability during the early critical healing period as determined by RFA-measurements. Résumé La mise en charge précoce après l'insertion de l'implant acquière beaucoup d'intérêt en médecine dentaire. La stabilité primaire de l'implant, qui est par exemple définie par l'instrumentation de fréquence de résonnance RFA, a été isolée comme un annonciateur lorsque la mise en charge de l'implant était précoce ou immédiate. Le but de cette étude a été d'étudier l'effet d'une mise en charge précoce (sept jours) sur l'établissement de l'ostéïntégration à l'aide de RFA (Osstell®). Des implants titane percutanés ont été insérés dans les deux tibias de dix cobayes. Une semaine après le placement des implants, un implant test a été mis en charge tous les jours pendant six semaines tandis que le contralatéral servait de contrôle et n'était pas mis en charge. Un moment sinusoïdal a été appliquéà une fréquence de trois hertz et une amplitute d'une force de 5 N pour 1 800 cycles. La fréquence de résonnance a été mesurée lors de l'insertion de l'implant et ensuite hebdomadairement en utilisant le RFA. Contrairement aux implants contrôles, qui accusaient une diminution de la stabilité une semaine après leur insertion atteignant un minimum après trois semaines (,200 Hz), les implants tests ont montré une augmentation progressive de la stabilité avec le temps. Après six semaines, la fréquence de résonnance moyenne des implants tests et contrôles atteignaient les mêmes valeurs. Comme décrit dans la littérature récente, la mise en charge précoce ne met pas en danger l'établissement de l'ostéoïntégration des implants en titane. Au contraire, une mise en charge contrôlée est bénéfique au maintien de la stabilité implantaire durant la période de guérison critique précoce comme déterminée par les mesures RFA. Zusammenfassung Die Belastung kurz nach der Implantatplatzierung hat in der Zahnmedizin schnell an Interesse gewonnen. Die Primärstabilität der Implantate, bestimmt z.B. durch Messung der Resonanzfrequenz, hat sich als Voraussagewert herauskristallisiert, wenn eine Sofort-oder Frühbelastung der Implantate durchgeführt wird. Das Ziel dieser Studie war, den Einfluss der frühen (nach 7 Tagen) mechanischen Belastung auf die Ausbildung der Osseointegration mittels Resonanzfrequenzanalyse (RFA) zu untersuchen. In die beiden Tibias von 10 Meerschweinchen wurden perkutane Titanimplantate eingesetzt. Eine Woche nach der Implantation wurde ein Implantat (Test) während 6 Wochen täglich belastet, während das kontralaterale Implantat unbelastet blieb (Kontrolle). Es wurde ein Biegemoment mit sinusoidalen Schwankungen mit einer Frequenz von 3 Hz und einer Kraftamplitude von 5 N in 1800 Zyklen appliziert. Die Resonanzfrequenz wurde nach der Implantation und dann wöchentlich mit einem RFA-Gerät (Osstell®) gemessen. Im Gegensatz zu den Kontrollimplantaten, welche eine Woche nach dem Setzen eine Stabilitätsabnahme zeigten und das Minimum nach drei Wochen (,200 Hz) erreichten, konnte bei den Testimplantaten eine progressive Zunahme der Stabilität über die Zeit beobachtet werden. Nach sechs Wochen erreichten die mittleren Resonanzfrequenzen der Test-und Kontrollimplantate dieselben Werte. Die frühe Belastung gefährdet die Ausbildung einer Osseointegration bei Titanimplantaten nicht, was auch durch die neuere Literatur bestätig wird. Im Gegenteil, eine kontrollierte Belastung ist von Vorteil für den Erhalt der Implantatstabilität während der kritischen frühen Einheilphase. Dies konnte mittels RFA Messungen ermittelt werden. Resumen La carga temprana tras la colocación del implante ha ganado rápidamente interesen odontología. Se ha aislado como predictor, la estabilidad primaria del implante, definida por instrumentación de frecuencia de resonancia, cuando se aplica la carga temprana al implante. La intención del estudio fue investigar el efecto de carga mecánica temprana (tras 7 días) en el establecimiento de la osteointegración por medio del análisis de la frecuencia de resonancia (RFA). Se instalaron implantes de titanio percutaneos en ambas tibias de 10 conejos de indias. Una semana tras la instalación, un implante (prueba) se cargó diariamente durante 6 semanas, mientras que el contralateral sirvió como el implante sin carga (control). Se aplicó un momento de flexión variante sinusoidalmente a una frecuencia de 3 Hz y una amplitud de la fuerza de 5 N, durante 1899 ciclos. Se midió la frecuencia de resonancia al instalar el implante y a partir de ahí semanalmente usando el dispositivo RFA (Ostell®). Contrariamente a los implantes de control, que mostraron una disminución de la estabilidad una semana después de la instalación, alcanzando un mínimo a las tres semanas (,200 Hz), los implantes de prueba mostraron un incremento progresivo de la estabilidad a lo largo del tiempo. Tras seis semanas, la frecuencia de resonancia de los implantes de prueba y de control alcanzaron los mismos valores. Tal como se confirma por la literatura reciente, la carga temprana no debe hacer peligrar el establecimiento de la osteointegración de los implantes de titanio. Por lo contrario, la carga controlada es beneficiosa para mantener la estabilidad de los implantes durante el periodo crítico de la cicatrización determinado por las mediciones de RFA. [source] |