Ideal Solution (ideal + solution)

Distribution by Scientific Domains

Selected Abstracts

Systematic optimization for the evaluation of the microinjection molding parameters of light guide plate with TOPSIS-based Taguchi method

Te-Li Su
Abstract A back light module is a key product for providing sufficient light source for a liquid crystal display (LCD). The light guide plate (LGP), used to increase the light usage rate, is a key component in the back light module. This study researches the microinjection molding process parameters and the quality performance of the LGP. Its purpose was to develop a combining Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) with the Taguchi method. This is to optimize the multiquality performance of the LGP for the injection molding manufacturing process, in which both the LCD and the LGP spontaneously produce the best quality performance for V-cut depth and angle. First, an L18 orthogonal array was planned for the manufacturing parameters that affect the microinjection molding process. These included cooling time, mold temperature, melt temperature, injection speed, injection pressure, packing pressure, packing switching, and packing time. The TOPSIS was used to deal with the single-quality optimization disadvantage of the Taguchi method. Then, the TOPSIS response table was used to obtain the optimized manufacturing parameters combination for a multiresponse process optimization. From the analysis of variance, the significant factors for the quality performance of the LGP could be obtained. In other words, by controlling these factors, it was possible to efficiently control the quality performance of the LGP. Finally, with the five verified experiments, the optimized processing parameters came within a 95% confidence interval. 2010 Wiley Periodicals, Inc. Adv Polym Techn 29:54,63, 2010; Published online in Wiley InterScience ( DOI 10.1002/adv.20181 [source]

Technical decomposition approach of critical to quality characteristics for Product Design for Six Sigma

Yihai He
Abstract Product Design for Six Sigma (DFSS) approach is a structural and disciplined methodology driven by critical to quality characteristics (CTQs). How to identify and decompose the CTQs is the kernel part in the DFSS process. Traditional method only depends on the quality function deployment (QFD) matrix to flow down CTQs roughly. The paper puts forward a novel technical approach for CTQs decomposition from customer requirements into critical technical parameters based on the relational tree. Specifically, this approach emphasizes the systematic process and quantitative computation on quality relation weight. In order to specify the object of product DFSS, the connotation and evolution model of CTQs are created first. Then along the product development process, a decomposition measure for relational tree of CTQs is studied based on the functional and physical trees in Axiomatic Design (AD). And the quality relation weight computation of its nodes by means of Rough Set and fuzzy Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) is explored. Finally, an application on a car body noise vibration harshness (NVH) improvement, as an example, is given, and the decomposition process of NVH related with the functional and physical trees as well as its node weights computation algorithm are expounded in detail. Copyright 2009 John Wiley & Sons, Ltd. [source]

Unfair Priority for HCC: A Problem Whose Ideal Solution Remains Unsolved

M. L. Volk
The ideal solution to priority for HCC will require better tools to predict survival benefit from liver transplantation. See article by Washburn et al on page 1652. [source]

The ecological challenge of immunocontraception: editor's introduction

N.D. Barlow
Summary 1. ,The problems of vertebrate pests are greater now than ever before, with vertebrate control constrained by problems of humaneness, scale and environmental impact. However, immunocontraception involves a conceptually ideal solution. Although not intrinsically novel, its delivery in baits or by a self-spreading vector and its effectiveness in pest control, are now the focus of growing international interest. 2. ,Major ecological questions correspond to the two forms of delivery: baits and vectors. First, given an effective immunocontraceptive, inserted into a bait and eaten by a pest, would the resulting level of sterilization in the population effectively suppress densities? Secondly, given that the immunocontraceptive agent can be inserted into a microparasitic or macroparasitic infective vector, would the modified vector persist at sufficient prevalence in the host population, and hence suppress densities to the required extent? 3. ,The papers published in this Special Profile focus on behaviour following sterilization or they model the likely impact of viral-vectored immunocontraception. They highlight advantages and disadvantages of immunocontraception and some general, novel and specific issues. These include the possibility of behaviourally mediated population responses to fertility control; the possible advantages of a mixed baiting and vector strategy; the competitiveness of a modified vector; the appropriateness of immunocontraception for controlling invasive vertebrates on islands; and the need for a ,pay-off' methodology for assessing genetic modifications against alternatives. 4. ,The findings offer significant benefits for management and policy: they will inform decisions on whether to pursue immunocontraception as a control option, and they provide evidence about efficacy and risk in applications to release genetically modified vectors. 5. ,Although many of the problems in developing immunocontraception technology are biotechnological, questions about the effectiveness of immunocontraceptive pest control are ultimately in the domain of ecologists. [source]

Using the polymer partitioning method to probe the thermodynamic activity of poorly water-soluble drugs solubilized in model lipid digestion products

Ben J. Boyd
Abstract The thermodynamic activity of solubilized drug is an important determinant of the extent of absorption of lipophilic drugs from the gastrointestinal tract. In this study, the polymer partitioning method was evaluated for its use in the determination of the thermodynamic activity of lipophilic drugs when solubilized in colloidal digestion products, using drug in dilute solution as a reference ideal solution. The lipophilic drugs griseofulvin, diazepam, and danazol partitioned into a polymeric receiver phase from non-micellar solution as a function of drug lipophilicity. The concentration of drug that partitioned into the polymer was linearly proportional to the concentration of free drug in solution, and this allowed the measured partition coefficient to be utilized as an indicator of the drug activity coefficient. The addition of a solubilizing species such as bile salt micelles caused a reduction in drug activity of a similar magnitude to that predicted from micelle equilibrium solubility data in the identical micellar solutions. The addition of micelle swelling lipids such as lecithin and fatty acids resulted in further reductions in activity coefficient. The ability to measure drug activity in model digestive systems has potential for application in the rational development of improved lipid-based formulations of poorly water-soluble drugs for oral administration. 2003 Wiley-Liss, Inc. and the American Pharmaceutical Association J Pharm Sci 92:1262,1271, 2003 [source]

Thermodynamic Assessment of the Gallium-Oxygen System

Matvei Zinkevich
The experimental information relevant to the Ga-O binary system has been critically assessed. A self-consistent set of Gibbs energy functions describing the phases in this system and a phase diagram are presented for the first time. The adjustable parameters of the models are obtained by a least-squares fit to the experimental data. The liquid phase is described by Hillert's partially ionic liquid model. The gallium oxides (,-, ,-, ,-, and ,-Ga2O3) are modeled as stoichiometric phases. The gas phase is treated as an ideal solution of the species Ga, Ga2, Ga2O, GaO, O, O2, and O3. The calculated phase diagram and thermodynamic properties agree very well with most of the experimental measurements. [source]

The need for patellar resurfacing in total knee arthroplasty: a literature review

John D. Swan
Abstract The controversy over whether or not to routinely resurface the patella during a total knee arthroplasty has persisted despite three decades of successful joint replacement procedures. Advocates for routine patellar resurfacing admit the occasional need for secondary patellar resurfacing and declare increased incidence of anterior knee pain in patients with non-resurfaced patellae as a cause for worry. Surgeons that leave the patella unresurfaced cite avoidance of complications that include patellar fracture, avascular necrosis, patellar tendon injury and instability. This review discusses the available literature on patellar resurfacing through an evidence-based analysis of randomized and pseudo-randomized controlled trials and published meta-analyses to date. The published literature seems to favour resurfacing the patellar routinely. Selective patellar resurfacing would be the ideal solution if sound pre-operative criteria could be established. So far, a method for accurately predicting which patients can avoid patellar resurfacing has not been found. Future research looking at patellar resurfacing should concentrate on developing criteria for selecting those patients that would benefit from patellar resurfacing and those that would do as well without resurfacing, and thus, limiting potential surgical complications. [source]