Highly Enantioselective Michael Addition (highly + enantioselective_michael_addition)

Distribution by Scientific Domains


Selected Abstracts


Back to Natural Cinchona Alkaloids: Highly Enantioselective Michael Addition of Malononitrile to Enones

ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 18 2009
Alessio Russo
Abstract An efficient and convenient highly enantioselective Michael addition of malononitrile to enones has been developed by using quinine as the organocatalyst. The adducts were isolated in excellent yield and high asymmetric induction (up to 95% ee). An easy route to difficultly accessible ester derivatives has been also disclosed. [source]


ChemInform Abstract: Noyori,s Ts-DPEN Ligand: Simple Yet Effective Catalyst for the Highly Enantioselective Michael Addition of Acetone to Nitroalkenes.

CHEMINFORM, Issue 35 2010
Lin Peng
No abstract is available for this article. [source]


ChemInform Abstract: Ionic Liquid Supported (ILS) (S)-Pyrrolidine Sulfonamide, a Recyclable Organocatalyst for the Highly Enantioselective Michael Addition to Nitroolefins.

CHEMINFORM, Issue 27 2009
Bukuo Ni
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]


ChemInform Abstract: Organocatalytic Highly Enantioselective Michael Addition of 2-Hydroxy-1,4-naphthoquinones to Nitroalkenes.

CHEMINFORM, Issue 44 2008
Wen-Ming Zhou
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]


ChemInform Abstract: Highly Enantioselective Michael Addition of Malononitrile to ,,,-Unsaturated Ketones.

CHEMINFORM, Issue 21 2008
Xuefeng Li
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]


ChemInform Abstract: Pyrrolidine,Pyridinium Based Organocatalysts for Highly Enantioselective Michael Addition of Cyclohexanone to Nitroalkenes.

CHEMINFORM, Issue 3 2008
Dan-Qian Xu
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]


Highly Enantioselective Michael Addition of Malononitrile to Vinylogous Imine Intermediates Generated in situ from Arylsulfonyl Indoles

CHEMISTRY - A EUROPEAN JOURNAL, Issue 36 2010
Linhai Jing
Malononitrile on rare form: Highly enantioselective Michael addition of malononitrile to vinylogous imine intermediates 2, generated in situ from arylsulfonyl indoles 1, is described (see scheme). This protocol provides easy and convenient access to valuable 3-indolyl derivatives 3 in high yields and enantioselectivities. A possible catalytic mechanism is proposed. [source]


Highly Enantioselective Michael Addition of Cyclic 1,3-Dicarbonyl Compounds to ,,,-Unsaturated ,-Keto Esters

ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 10 2010
Xing-Kuan Chen
Abstract A highly enantioselective Michael addition of cyclic 1,3-dicarbonyl compounds to ,,,-unsaturated ,-keto esters catalyzed by amino acid-derived thiourea-tertiary-amine catalysts is presented. Using 5,mol% of a novel tyrosine-derived thiourea catalyst, a series of chiral coumarin derivatives were obtained in excellent yields (up to 99%) and with up to 96% ee under very mild conditions within a short reaction time. [source]


Highly Enantioselective Michael Addition Reactions of 3-Substituted Benzofuran-2(3H)-ones to Chalcones Catalyzed by a Chiral Alkyl-Substituted Thiourea

ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 7 2010
Xin Li
Abstract A highly enantioselective Michael addition of 3-substituted benzofuran-2(3H)-ones to chalcones catalyzed by a chiral bifunctional thiourea was developed. Several chiral 3,3,-substituted benzofuran-2(3H)-ones derivatives, bearing adjacent quaternary-tertiary stereocenters, were efficiently synthesized with excellent enantioselectivities. [source]


Back to Natural Cinchona Alkaloids: Highly Enantioselective Michael Addition of Malononitrile to Enones

ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 18 2009
Alessio Russo
Abstract An efficient and convenient highly enantioselective Michael addition of malononitrile to enones has been developed by using quinine as the organocatalyst. The adducts were isolated in excellent yield and high asymmetric induction (up to 95% ee). An easy route to difficultly accessible ester derivatives has been also disclosed. [source]