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Herpes Simplex Infection (herpes + simplex_infection)

Distribution by Scientific Domains
Medical Sciences100%

Selected Abstracts

ERRATUM: Female Genital Tract Secretions Inhibit Herpes Simplex Infection: Correlation with Soluble Mucosal Immune Mediators and Impact of Hormonal Contraception

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, Issue 5 2010
Gail F. Shust
No abstract is available for this article. [source]

,Specific' cutaneous infiltrate of B-cell chronic lymphocytic leukemia at the site of a florid herpes simplex infection

JOURNAL OF CUTANEOUS PATHOLOGY, Issue 8 2005
Mirjana Ziemer
Background:, Specific cutaneous infiltrates in patients with leukemia generally carry a grim prognosis. However, non-neoplastic skin diseases may be associated with recruitment of normal and neoplastic leukocytes circulating in the peripheral blood. In those instances, neoplastic cells may be detected in skin lesions without an adverse effect on prognosis. Methods:, In a patient with B-cell chronic lymphocytic leukemia, a specific infiltrate developed at the site of a florid herpes simplex infection. Clinically, the lesion presented itself as an ulcerated tumor. Results:, Histopathologically, the lesion was characterized by a dense, diffuse infiltrate of small hyperchromatic lymphocytes throughout the entire dermis. Lymphocytes showed an aberrant CD20+/CD43+/CD5+ phenotype of neoplastic B cells, and monoclonal rearrangement of immunoglobulin gamma genes could be demonstrated by polymerase chain reaction. Although criteria for leukemia cutis were fulfilled, the patient did well. Conclusions:, The cutaneous infiltrate of neoplastic cells seemed to be part of a physiologic response to the antigenic stimulus, rather than indicating an exacerbation of leukemia. [source]

Disseminated granuloma annulare following erythema multiforme minor

AUSTRALASIAN JOURNAL OF DERMATOLOGY, Issue 4 2000
Zeev Abraham
SUMMARY A 44-year-old woman presented with erythema multiforme minor followed by disseminated granuloma annulare 4 weeks later. The patient was not taking any medication and had no history of herpes simplex infection. Involvement of a delayed-type hypersensitivity reaction in the pathogenesis of these two well known disorders, as suggested by immunological investigations, may explain their concurrence in our patient. The substitution of the erythema multiforme minor lesions by an eruption of disseminated granuloma annulare at the same sites suggests the possibility of a Koebner phenomenon or an isotopic response. [source]