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Gland Mass (gland + mass)

Distribution by Scientific Domains

Medical Sciences	60%

Selected Abstracts

Value of Fine-Needle Aspiration Cytology of Parotid Gland Masses

THE LARYNGOSCOPE, Issue 11 2001
Peter Zbären MD
Abstract Objective To evaluate the usefulness and accuracy of fine-needle aspiration cytology (FNAC) in the diagnosis of parotid gland masses. Study Design Retrospective chart review of patients undergoing FNAC. Methods Between January 1990 and December 1998, 410 parotid glands were resected at the Department of Otorhinolaryngology,Head and Neck Surgery at the University of Berne, Inselpital (Berne, Switzerland). Included in the study were 228 cases with preoperative FNAC. In a retrospective study the results of FNAC were analyzed and compared with the corresponding histopathological diagnosis. Results Histological evaluation revealed 65 malignant tumors and 163 benign lesions (150 neoplasms and 13 nonneoplastic lesions). The cytological findings were nondiagnostic in 13 (5.7%), true-negative in 146 (64%), true-positive in 39 (17%), false-negative in 22 (9.8%) and false-positive in 8 (4.5%) cases in detecting malignant tumors. Nineteen of 39 (49%) malignant tumors (true-positive) and 123 of 146 (84%) benign lesions (true-negative) were classified accurately. The accuracy, sensitivity, and specificity were 86%, 64%, and 95% respectively. Conclusions Fine-needle aspiration cytology is a valuable adjunct to preoperative assessment of parotid masses. Preoperative recognition of malignant tumors may help prepare both the surgeon and patient for an appropriate surgical procedure. [source]

Metastatic hepatocellular carcinoma to the mandible masquerading as a parotid gland mass: A potential pitfall in the diagnosis by fine needle aspiration biopsy

DIAGNOSTIC CYTOPATHOLOGY, Issue 10 2007
Liying Han M.D., Ph.D.
No abstract is available for this article. [source]

Unsuspected systemic amyloidosis diagnosed by fine-needle aspiration of the salivary gland: Case report

DIAGNOSTIC CYTOPATHOLOGY, Issue 1 2004
Ph.D., Tamar Giorgadze M.D.
Abstract Amyloidosis of the head and neck region may represent a local amyloidoma or a manifestation of systemic disease. Involvement of major salivary glands by either primary or secondary forms of amyloidosis is very rare. We describe a case of systemic amyloidosis that initially presented as submandibular gland mass and was diagnosed by fine-needle aspiration (FNA). A 69-year-old male presented with submandibular mass. His past medical history was significant for left forearm melanoma that was excised 6 years ago and tricuspid valve endocarditis after valvular replacement 3 months prior to FNA of the submandibular gland. The patient had no symptoms or clinical and laboratory data suggestive of amyloidosis. FNA specimen showed salivary gland tissue and abundant amorphous material, which stained positive for amyloid with Congo red stain and showed typical birefringence when examined by polarized microscopy. Further workup of the patient revealed generalized amyloidosis with multiorgan involvement by the disease. This case demonstrates that FNA can be a useful technique in the diagnosis of unsuspected amyloidosis. Diagn. Cytopathol. 2004;31:57,59. © 2004 Wiley-Liss, Inc. [source]

Using the composite variables of reproductive morphology, histology and steroid hormones to determine age and size at sexual maturity for the thorny skate Amblyraja radiata in the western Gulf of Maine

JOURNAL OF FISH BIOLOGY, Issue 5 2006
J. A. Sulikowski
Age at size was linked to sexual maturity in 77 male and 93 female thorny skates Amblyraja radiata from the western Gulf of Maine using three criteria: 1) gross reproductive morphology, 2) histology and 3) steroid hormone concentrations. Age-bias plots and the coefficient of variation from vertebral band counts suggested that the ageing method represented a non-biased and precise approach to the age assessment of A. radiata. Maturity ogives for males, based on data gathered for clasper length, circulating testosterone concentrations and proportion of mature spermatocysts within the testes, predicted that 50% maturity occurred at a total length (LT) of 865 mm and c. 10·90 years of age. For females, maturity ogives, based on data gathered for ovary mass, shell gland mass, follicle size and circulating oestradiol concentrations, predicted that 50% maturity occurred at 875 mm LT and c. 11·00 years of age. Collectively, the results suggest that analysis of several contemporaneous reproductive variables offers an accurate determination of sexual maturity in the thorny skate. [source]

Morphological Features of the Stomach of Malayan Pangolin, Manis javanica

ANATOMIA, HISTOLOGIA, EMBRYOLOGIA, Issue 5 2010
C. Nisa'
With 6 figures Summary The morphology of the stomach of Malayan pangolin, Manis javanica was studied at macroscopic, light microscopic, and scanning electron microscopic levels. The stomach of M. javanica was C-shaped with short lesser curvature. At the oesophageal junction, the inner smooth muscle was thickened in the greater curvature side. The entire stomach was lined by a thick cornified stratified squamous epithelium, except at the duct orifices of glands and in the pyloric gland region. The wall of the fundus was thin and devoid of glands. The gastric glands consisted of mucous, oxyntic, and pyloric glands. The mucous glands were observed in the lesser curvature (Mg-L), in the greater curvature (Mg-G), and in the pyloric canal (Mg-C) respectively. The oxyntic glands were organized into gland mass, making an oval mound elevated to the gastric lumen, in the middle of the greater curvature. The oxyntic gland mass has a single common duct with opening directed to the pyloric side. This duct was surrounded by mucus gland (Mg-G). The pyloric glands were located caudal to the pylorus. There was no sphincter at the pyloric-duodenal junction. Large mucosal protuberance, the torus pyloricus was observed in the side of the lesser curvature of the pyloric canal. In the lumen of pyloric canal region, numerous spines and small pebbles were observed. The muscle layers in the wall of this region were considerably thickened. The present results on the stomach of M. javanica are thought to be closely related to the toothless and eating habits of this animal species. [source]

Morphology and Histology of the Atlantic Bottlenose Dolphin (Tursiops truncatus) Adrenal Gland with Emphasis on the Medulla

ANATOMIA, HISTOLOGIA, EMBRYOLOGIA, Issue 2 2005
L. S. Clark
Summary This study provides the first detailed description of the Atlantic bottlenose dolphin (Tursiops truncatus) adrenal gland with emphasis on the medulla. Thirty-one dolphins of varying age and sex were used in this study. No statistical differences were found between the right and left gland mass, however, the left was typically greater. Mean mass for the right and left adrenal glands were 4.99 ± 0.513 and 5.36 ± 0.558 g, respectively. No statistical differences were found between average gland mass and sexual maturity or sex. The average cortex/medulla ratio was 1.22 ± 0.060 meaning approximately 48% is cortex, 41% is medulla, and 11% was categorized as other (i.e. blood vessels, connective tissue, etc.). The cortex contained pseudolobules and the typical zonation. A medullary band, consisting of highly basophilic staining cells was found at the periphery of the medulla. Projections of the medulla to the gland capsule were noted. Immunolabelling with polyclonal antibodies against the enzymes dopamine , hydroxylase and phenylethanolamine N-methyl transferase indicated that noradrenaline producing cells are found throughout the medulla including the medullary band while adrenaline producing cells are only found within the medullary band. Transmission electron microscopy confirmed the presence of two distinct cell populations within the medullary band and a single cell population throughout the medulla. [source]

3445: Evaluation, diagnosis and grading of severity of MGD

ACTA OPHTHALMOLOGICA, Issue 2010
AJ BRON
Purpose To evaluate current diagnostic tests and make future recommendations. Methods An evidence-based review of procedures. Results MGD is a common symptomatic disorder leading to associated ocular surface disease including evaporative dry eye. A two stage diagnostic approach is recommended including an assessment of meibomian function based on lid morphology, gland mass, expressibility, lipid layer appearance and tear evaporation. A diagnosis of dry eye is based on measures of tear production and clearance, tear osmolarity, tear film stability and the presence of ocular surface changes revealed by tissue staining and inflammatory biomarkers. Quantification of MGD depends on grading meibum quality and expressibility. Newer, quantitative methods will make grading more accurate in the future and include quantitative meibomian expression, non-invasive meibography, confocal microscopy, video-interferometry and the use of inflammatory biomarkers. Meibomian gland dropout can be to monitor and stratify MGD in clinical trials. Conclusion A provisional severity rating of MGD and MGD-related disease has been proposed as a guide to the selection of treatment and the monitoring of disease progression. [source]

3464: Surgical treatment of lacrimal gland tumours

ACTA OPHTHALMOLOGICA, Issue 2010
D BRISCOE
Purpose The surgical treatment of Lacrimal gland tumors is often controversial and not so clear cut. Imaging and a full systemic evaluation lead to the decision as to which surgical approach best serves our purposes. The surgical management of Lacrimal gland tumors is discussed and the results of 31 cases in my experience are presented. Methods The surgical approach used is carefully chosen according to the type of disease presentation. All 31 patients in this series had neuroimaging and full work up and 30 underwent incision or excision biopsy. Selected cases are discussed. Results : Surgical Approaches chosen for the Lacrimal gland in this case series included Trans-Septal Orbitotomy, and Lateral Orbitotomy. Disease spectrum included Idiopathic orbital inflammatory disease (8), Orbital Sarcoid (7), Lymphoma (3), Sjrogens disease (3), Benign Mixed Tumour (2), Infectious mononucleosis (2) Angiolymphoid Hyperplasia (2), Sebaceous Cell Carcinoma (1), Churge Strause syndrome (1), Dermoid Cyst (1), Epithelial Inclusion Cyst(1). Conclusion Biopsy of a Lacrimal gland mass is relatively simple and is recommended. The approach should be considered carefully and an excision biopsy should be performed where possible. Surgical management and surprising pathology results can have significant implications for the patient. [source]