Alkyl Halides (alkyl + halide)

Distribution by Scientific Domains
Distribution within Chemistry


Selected Abstracts


Reduction of Alkyl Halides by Triethylsilane Based on a Cationic Iridium Bis(phosphinite) Pincer Catalyst: Scope, Selectivity and Mechanism

ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 1-2 2009
Jian Yang
Abstract A highly efficient procedure for the reduction of a broad range of alkyl halides by triethylsilane based on a cationic iridium bis(phosphinite) pincer catalyst has been discovered and developed. This reduction chemistry is chemoselective and has unique selectivities compared with conventional radical-based processes and the aluminum trichloride/triethylsilane (AlCl3/Et3SiH) and triphenylmethyl tetrakis[pentafluorophenyl]borate/triethylsilane {[Ph3C] [B(C6F5)4]/Et3SiH} systems. Reductions use three equivalents of triethylsilane relative to the halide and can be carried out with very low catalyst loadings and in a solvent-free manner, which may provide an environmentally attractive and safe alternative to many currently practiced methods for reduction of alkyl halides. Mechanistic studies reveal a unique catalytic cycle. The cationic iridium hydride 2,6-bis[di-(tert -butyl)phosphinyloxy)phenyl(hydrido)iridium, (POCOP)IrH+ {POCOP= 2,6-[OP(t- Bu)2]2C6H3} binds and activates the silane. This complex serves as a potent silylating reagent to generate silyl halonium ions, Et3SiXR+, which are reduced by the neutral iridium dihydride to yield alkane product and regenerate the cationic (POCOP)IrH+, thus closing the catalytic cycle. All key intermediates have been identified by in situ NMR monitoring and kinetic studies have been completed. An application of this reduction system to the catalytic hydrodehalogenation of a metal chloride complex is also described. [source]


Copper Nanoparticles on Charcoal for Multicomponent Catalytic Synthesis of 1,2,3-Triazole Derivatives from Benzyl Halides or Alkyl Halides, Terminal Alkynes and Sodium Azide in Water as a "Green" Solvent

ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 1-2 2009
Hashem Sharghi
Abstract A one-pot procedure for synthesis of 1,2,3-triazole derivatives via the three-component coupling (TCC) reaction between terminal alkynes, benzyl or alkyl halides, and sodium azide in the presences of 1,mol% nanoparticles copper/carbon (Cu/C) catalyst has been developed. The catalyst showed high catalytic activity and 1,4-regioselectivity for the [3+2],Huisgen cycloaddition in water as a "green" solvent and good to excellent yields were obtained in all cases. This procedure eliminates the need to handle organic azides, and they are generated in situ. The reaction has a broad scope and is especially practical for the synthesis of new azacrown ether and anthraquinone derivatives of triazole. The heterogeneous catalysts were fully characterized by scanning electron microscopy (SEM), atomic forced microscopy (AFM), X-ray diffraction (XRD), inductively coupled plasma (ICP) analysis and FT-IR experimental techniques. The catalyst was recycled ten times without significant loss of activity. [source]


Topological Electronegativity Index and Its Application , I. Ionization Potentials of Alkyl Groups and Alkyl Halides

MOLECULAR INFORMATICS, Issue 9 2007
Chenzhong Cao
Abstract A Topological Electronegativity Index (TEI) for alkyl group was developed, based on the bond adjacency matrix of the radical atom. Taking the radical atom and the adjacency atoms (or groups) as the vertices of molecular graph of the alkyl group, the bond adjacency matrix was constructed, in which the diagonal elements were assigned the Pauling electronegativity of the atom (or group), and the off-diagonal elements were assigned values 1 or 0. The off-diagonal elements represent the bond connections: that is when the two atoms (or groups) connect with each other, it is 1; otherwise is 0. From the matrix, the eigenvalues were obtained and its geometric mean value was considered as the TEI of an alkyl. The calculated TEI has good correlation with its experimental ionization potential. Further, the TEI was applied to correlate with the ionization potentials of alkyl halides and substituted ethenes, and to correlate with the Bond Dissociation Energies (BDEs) of the CiH bonds in alkanes. [source]


Palladium(II)-Catalyzed ortho Alkylation of Benzoic Acids with Alkyl Halides,

ANGEWANDTE CHEMIE, Issue 33 2009
Yang-Hui Zhang Dr.
Wettbewerbsvorteil: Bei der PdII -katalysierten Reaktion von Benzoaten mit Alkylhalogeniden wird eine Aryl-C-H-Bindung aktiviert, bevor die konkurrierende Alkylierung des Carboxylations stattfinden kann. Auf die Alkylierung folgte eine intramolekulare Lactonisierung, die weit anwendbare ,- und ,-Benzolactone ergab (siehe Schema). [source]


ChemInform Abstract: Organozinc Generation via the Titanium-Catalyzed Activation of Alkyl Halides.

CHEMINFORM, Issue 20 2010
Lauren M. Fleury
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]


ChemInform Abstract: Nickel Complexes of a Pincer Amidobis(amine) Ligand: Synthesis, Structure, and Activity in Stoichiometric and Catalytic C,C Bond-Forming Reactions of Alkyl Halides.

CHEMINFORM, Issue 32 2009
Oleg Vechorkin
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]


ChemInform Abstract: Reduction of Alkyl Halides by Triethylsilane Based on a Cationic Iridium Bis(phosphinite) Pincer Catalyst: Scope, Selectivity and Mechanism.

CHEMINFORM, Issue 23 2009
Jian Yang
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]


ChemInform Abstract: Improved Chemoselective, eco-Friendly Conditions for the Conversion of Primary Alkyl Halides into Nitroalkanes under PEG400.

CHEMINFORM, Issue 1 2009
Roberto Ballini
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]


ChemInform Abstract: Indium,Copper and Indium,Silver Mediated Barbier,Grignard-Type Alkylation Reaction of Aldehydes Using Unactivated Alkyl Halides in Water

CHEMINFORM, Issue 38 2008
Zhi-Liang Shen
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]


ChemInform Abstract: Indium,Silver- and Zinc,Silver-Mediated Barbier,Grignard-Type Alkylation Reactions of Imines by Using Unactivated Alkyl Halides in Aqueous Media.

CHEMINFORM, Issue 26 2008
Zhi-Liang Shen
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]


ChemInform Abstract: A Facile KF/Al2O3 -Mediated, One-Pot Synthesis of Symmetrical Trithiocarbonates from Alkyl Halides and Carbon Disulfide.

CHEMINFORM, Issue 22 2008
Barahman Movassagh
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]


One-Pot Synthesis of 1,2,3-Triazoles from Benzyl and Alkyl Halides, Sodium Azide and Alkynes and Water under Transition-Metal-Catalyst Free Reaction Conditions.

CHEMINFORM, Issue 31 2007
Pinhua Li
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]


Experimental and Theoretical Studies on Formal ,-Bond Metathesis of Silyl Tellurides with Alkyl Halides.

CHEMINFORM, Issue 20 2007
Shigeru Yamago
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]


4-Aminophenyldiphenylphosphinite (APDPP), a New Heterogeneous and Acid Scavenger Phosphinite , Conversion of Alcohols, Trimethylsilyl, and Tetrahydropyranyl Ethers to Alkyl Halides with Halogens or N-Halosuccinimides.

CHEMINFORM, Issue 9 2007
Nasser Iranpoor
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]


Cobalt-Catalyzed Trimethylsilylmethylmagnesium-Promoted Radical Alkenylation of Alkyl Halides: A Complement to the Heck Reaction.

CHEMINFORM, Issue 43 2006
Walter Affo
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]


Cobalt-Catalyzed Trimethylsilylmethylmagnesium-Promoted Radical Alkenylation of Alkyl Halides: A Complement to the Heck Reaction.

CHEMINFORM, Issue 43 2006
Walter Affo
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]


Cobalt(diamine)-Catalyzed Cross-Coupling Reaction of Alkyl Halides with Arylmagnesium Reagents: Stereoselective Constructions of Arylated Asymmetric Carbons and Application to Total Synthesis of AH13205.

CHEMINFORM, Issue 24 2006
Hirohisa Ohmiya
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]


Cobalt(diamine)-Catalyzed Cross-Coupling Reaction of Alkyl Halides with Arylmagnesium Reagents: Stereoselective Constructions of Arylated Asymmetric Carbons and Application to Total Synthesis of AH13205.

CHEMINFORM, Issue 24 2006
Hirohisa Ohmiya
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]


Cobalt-Catalyzed Reductive Coupling of Saturated Alkyl Halides with Activated Alkenes.

CHEMINFORM, Issue 23 2006
Paritosh Shukla
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]


Conversion of Alkyl Halides into Alcohols via Formyloxylation Reaction with DMF Catalyzed by Silver Salts.

CHEMINFORM, Issue 16 2006
Antonio Abad
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]


From Ketones, Aldehydes or Alkyl Halides to Terminal 1,1-Difluoroolefins Using BrF3.

CHEMINFORM, Issue 50 2005
Aviv Hagooly
Abstract For Abstract see ChemInform Abstract in Full Text. [source]


The Chemistry of Alkylstrontium Halide Analogues: Barbier-Type Alkylation of Imines with Alkyl Halides.

CHEMINFORM, Issue 45 2005
Norikazu Miyoshi
Abstract For Abstract see ChemInform Abstract in Full Text. [source]


A Task-Specific Ionic Liquid [bmim]SCN for the Conversion of Alkyl Halides to Alkyl Thiocyanates at Room Temperature.

CHEMINFORM, Issue 25 2005
Ahmed Kamal
Abstract For Abstract see ChemInform Abstract in Full Text. [source]


Organic Reactions in Water: An Efficient Zinc-Mediated Stereoselective Synthesis of (E)- and (Z)-Trisubstituted Alkenes Using Unactivated Alkyl Halides.

CHEMINFORM, Issue 52 2004
Biswanath Das
Abstract For Abstract see ChemInform Abstract in Full Text. [source]


SN2 Type Hydrolysis of Secondary Alkyl Halides and Sulfonates in Hydrothermal Water.

CHEMINFORM, Issue 46 2004
Yuki Yamasaki
Abstract For Abstract see ChemInform Abstract in Full Text. [source]


Organic Reactions in Ionic Liquids: N-Alkylation of Cyclic Imides with Alkyl Halides Promoted by Potassium Fluoride.

CHEMINFORM, Issue 42 2004
Yi Hu
Abstract For Abstract see ChemInform Abstract in Full Text. [source]


Phosphonium Chloride Catalyzed Dehydrochlorinative Coupling Reactions of Alkyl Halides with Hydridochlorosilanes.

CHEMINFORM, Issue 21 2003
Seung-Hyun Kang
Abstract For Abstract see ChemInform Abstract in Full Text. [source]


ChemInform Abstract: Cocatalysis by Tetravalent Tin Compounds in Phase -Transfer Catalyzed Fluorination of Alkyl Halides and Sulfonates.

CHEMINFORM, Issue 29 2002
Mieczyslaw Makosza
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]


ChemInform Abstract: Nickel-Catalyzed Cross-Coupling Between Functionalized Primary or Secondary Alkylzinc Halides and Primary Alkyl Halides.

CHEMINFORM, Issue 27 2002
Anne Eeg Jensen
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]


ChemInform Abstract: Effect of Fluorine Substituents on Catalytic Functionalizations of Alkyl Halides with Organostannanes.

CHEMINFORM, Issue 52 2001
Rie Shimizu
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]