Alkaloids

Distribution by Scientific Domains
Distribution within Chemistry

Kinds of Alkaloids

  • aconitum alkaloid
  • aporphine alkaloid
  • benzophenanthridine alkaloid
  • carboline alkaloid
  • cinchona alkaloid
  • daphniphyllum alkaloid
  • diterpenoid alkaloid
  • ergot alkaloid
  • hepatotoxic pyrrolizidine alkaloid
  • indole alkaloid
  • isomeric tropane alkaloid
  • isoquinoline alkaloid
  • major alkaloid
  • marine alkaloid
  • natural alkaloid
  • natural cinchona alkaloid
  • nectar alkaloid
  • new alkaloid
  • new diterpenoid alkaloid
  • protoberberine alkaloid
  • pyrrolizidine alkaloid
  • quinolizidine alkaloid
  • stemona alkaloid
  • steroidal alkaloid
  • total alkaloid
  • tropane alkaloid

  • Terms modified by Alkaloids

  • alkaloid biosynthesis
  • alkaloid concentration
  • alkaloid content
  • alkaloid derivative
  • alkaloid extract
  • alkaloid fraction
  • alkaloid isolated
  • alkaloid production
  • alkaloid profile

  • Selected Abstracts


    Trichocarpinine, a Novel Hetidine,Hetisine Type Bisditerpenoid Alkaloid from Aconitum tanguticum var. trichocarpum

    HELVETICA CHIMICA ACTA, Issue 1 2010
    Ling Lin
    Abstract Trichocarpinine (1), the first hetidine,hetisine type bisditerpenoid alkaloid, was isolated from the whole herbs of Aconitum tanguticum var. trichocarpum. Its structure was determined by a combination of spectroscopic techniques, including HR-ESI-MS and 1D- and 2D-NMR experiments. Its plausible biogenetic pathway was proposed as well (Scheme). [source]


    Cinchona Alkaloid,Metal Complexes: Noncovalent Porous Materials with Unique Gas Separation Properties,

    ANGEWANDTE CHEMIE, Issue 39 2010
    Prof.
    Smarte Poren: Zweikernige Aluminium-Cinchonin-Komplexe dienen als Bausteine zur Selbstorganisation chiraler Architekturen mit nichtkovalenten Wechselwirkungen (siehe Bild). Das flexible desolvatisierte Material mit Ultramikroporen ist ein selektives Adsorptionsmittel mit einzigartigen Eigenschaften, z.,B. hohen Affinitäten für H2, CO2 und CH4 und einer temperaturgeregelten Adsorption von N2. [source]


    Titelbild: Total Synthesis of Palau'amine (Angew. Chem.

    ANGEWANDTE CHEMIE, Issue 6 2010
    6/2010)
    Die pazifischen Palau-Inseln bieten eine außergewöhnliche Artenvielfalt, und von ebensolcher Exotik ist auch die Struktur des Naturstoffs Palau'amin, das zum meistgejagten Alkaloid in der Synthesechemie des 21. Jahrhunderts wurde. Die erste Totalsynthese von Palau'amin wird nun von P.,S. Baran und Mitarbeitern in der Zuschrift auf S.,1113,ff. beschrieben. Die erfolgreiche Syntheseroute umfasst Transformationen ungeschützter Zwischenstufen, Kaskadenreaktionen und einen bemerkenswerten Abschluss mit einer transannularen Cyclisierung zum Aufbau der entscheidenden Bindung. Bildentwurf Paul Krawczuk; Copyright iStockphoto.com/clumpner. [source]


    Cortistatin,A is a High-Affinity Ligand of Protein Kinases ROCK, CDK8, and CDK11,

    ANGEWANDTE CHEMIE, Issue 47 2009
    Victor
    Antiproliferatives Alkaloid: Cortistatin,A ist ein hochaffiner Ligand für einen kleinen Satz von Proteinkinasen, einschließlich der Rho-assoziierten Proteinkinase (ROCK), der Cyclin-abhängigen Kinase,8 (CDK8) und der Cyclin-abhängigen Kinase,11 (CDK11). Modelle von Cortistatin,A im Komplex mit einer kristallographischen Struktur von ROCK (siehe Bild) und ein Homologiemodell von CDK8 werden präsentiert. [source]


    ChemInform Abstract: Modified Cinchona Alkaloid,Zinc Complex Catalysts: Enantioselective Monoacetylation of Glycerol Derivatives with Acetic Anhydride.

    CHEMINFORM, Issue 21 2010
    Shigeki Sano
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]


    ChemInform Abstract: Chiral Amide from (1S,2R)-(+)-Norephedrine Alkaloid in the Enantioselective Addition of Diethylzinc to Aryl and Heteroaryl Aldehydes.

    CHEMINFORM, Issue 4 2010
    Nallamuthu Ananthi
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]


    A Short, Efficient, and Stereoselective Total Synthesis of a Pyrrolidine Alkaloid: (-)-Codonopsinine.

    CHEMINFORM, Issue 31 2007
    Jangari Santhosh Reddy
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]


    Total Synthesis of the Marine Alkaloid (.+-.)-Lepadiformine via a Radical Carboazidation.

    CHEMINFORM, Issue 36 2006
    Pascal Schaer
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]


    Asymmetric Aza-Mannich Reactions of Sulfinimines: Scope and Application to the Total Synthesis of a Bromopyrrole Alkaloid.

    CHEMINFORM, Issue 21 2006
    James C. Lanter
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]


    Enantioselective Total Synthesis of (2R,3R,6R)-N-Methyl-6- (deca-1,,3,,5,-trienyl)-3-methoxy-2-methylpiperidine, an Insecticidal Alkaloid.

    CHEMINFORM, Issue 21 2006
    Yusuke Nakatani
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]


    Synthesis of the Tetrahydroisoquinoline Alkaloid (.+-.)-Renieramycin G and a (.+-.)-Lemonomycinone Analogue from a Common Intermediate.

    CHEMINFORM, Issue 4 2006
    Philip Magnus
    No abstract is available for this article. [source]


    Senepodine F, a New C22N2 Alkaloid from Lycopodium chinense.

    CHEMINFORM, Issue 26 2005
    Yusuke Hirasawa
    No abstract is available for this article. [source]


    Enantioselective Syntheses of Two Diastereomers of 223V, an Alkaloid from the Poison Frog Dendrobates pumilio.

    CHEMINFORM, Issue 24 2005
    Naoki Toyooka
    Abstract For Abstract see ChemInform Abstract in Full Text. [source]


    Structure Elucidation and Synthesis of Lycoposerramine-B, a Novel Oxime-Containing Lycopodium Alkaloid from Lycopodium serratum Thunb.

    CHEMINFORM, Issue 24 2005
    Kazuaki Katakawa
    Abstract For Abstract see ChemInform Abstract in Full Text. [source]


    (-)-Amarbellisine, a Lycorine-Type Alkaloid from Amaryllis belladonna L. Growing in Egypt.

    CHEMINFORM, Issue 52 2004
    Antonio Evidente
    No abstract is available for this article. [source]


    A New Pyranoacridone Alkaloid from the Bark of Medicosma subsessilis (Rutaceae).

    CHEMINFORM, Issue 21 2004
    Nguyen Tuan Minh
    Abstract For Abstract see ChemInform Abstract in Full Text. [source]


    Cynthichlorine: A Bioactive Alkaloid from the Tunicate Cynthia savignyi.

    CHEMINFORM, Issue 15 2004
    A. Abourriche
    Abstract For Abstract see ChemInform Abstract in Full Text. [source]


    Chinchona Alkaloid Derived Ligands in Catalytic Asymmetric Transfer Hydrogenation.

    CHEMINFORM, Issue 46 2003
    Antti Hartikka
    No abstract is available for this article. [source]


    Total Synthesis of the Spermidine Alkaloid 13-Hydroxyisocyclocelabenzine

    CHEMINFORM, Issue 29 2003
    Yi Li
    Abstract For Abstract see ChemInform Abstract in Full Text. [source]


    New Diterpenoid Alkaloid from Spiraea formosana.

    CHEMINFORM, Issue 50 2002
    Tian-Shung Wu
    No abstract is available for this article. [source]


    ChemInform Abstract: Indolopyridoquinazoline Alkaloid from Leptothyrsa sprucei.

    CHEMINFORM, Issue 21 2002
    Xing-Cong Li
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]


    ChemInform Abstract: An Immunosuppressive Tryptophan-Derived Alkaloid from Lepidagathis cristata

    CHEMINFORM, Issue 21 2002
    V. Ravikanth
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]


    A New Indole Alkaloid and Anti-Inflammatory Constituents from Strychnos cathayensis

    CHEMISTRY & BIODIVERSITY, Issue 7 2008
    Jih-Jung Chen
    Abstract A new indole alkaloid, 11,12-dimethoxyhenningsamine (1), was isolated from the roots of Strychnos cathayensis, together with 19 known compounds. The structure of this new compound was determined through spectroscopic and mass-spectrometric analyses. Among the isolated compounds, 11-methoxyhenningsamine (3) and aesculetin dimethyl ether (4) exhibited potent inhibition (IC50<5.5,,g/ml) on superoxide-anion generation and elastase release by human neutrophils in response to fMet-Leu-Phe/cytochalasin B. [source]


    Chenoalbicin, a Novel Cinnamic Acid Amide Alkaloid from Chenopodium album

    CHEMISTRY & BIODIVERSITY, Issue 10 2004
    Francesca Cutillo
    The roots of Chenopodium album were infused in MeOH, and the extract was partitioned between AcOEt and H2O. AcOEt-Soluble material was subjected to different silica-gel column chromatographies and then purified by reverse-phase HPLC to afford a new cinnamic acid amide alkaloid as a racemic mixture. The new compound, named chenoalbicin (1), was characterized by extensive spectroscopic investigation, especially 1D and 2D NMR spectroscopy. Its effects on the germination and growth of Lactuca sativa L. has been studied. The results are reported as percentage differences of germination, root elongation, and shoot elongation from the control at concentrations ranging from 10,4 to 10,7,M. [source]


    Efficient and Chirally Specific Synthesis of Phenanthro-Indolizidine Alkaloids by Parham-Type Cycloacylation

    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 2 2010
    Ziwen Wang
    Abstract A concise, efficient and modular route involving Parham-type cycloacylation as the key step has been used to synthesize six enantiopure phenanthro-indolizidine alkaloids 1a,c. The preparation of enantiomerically pure tylophora alkaloids and their seco analogues on a large-scale is now feasible. The alcohol intermediates 8a,c, which are difficult to prepare by other synthetic methodologies, have been synthesized by a metallation,cyclization,reduction sequence in excellent yields. [source]


    Strategies for the Synthesis of Stemona Alkaloids,

    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 15 2009
    Ramon Alibés
    Abstract The extracts of several plants of the Stemonaceae family have long been used in Asian countries against differentdiseases and for their antiparasitic properties. Significant constituents of these extracts are a series of structurally related secondary metabolites named Stemona alkaloids. All the Stemona alkaloids are polycyclic and contain multiple stereocenters. Most of them present a central pyrrolo[1,2- a]azepine system and the majority also incorporate at least one ,-methyl-,-butyrolactone substructure. Their challenging molecular architectures have motivated the development of new strategies for the construction of their skeletons, but only a small number of total syntheses have been published and they are still limited to quite a small number of targets. This microreview briefly examines most of the synthetic approaches to these alkaloids, according to the strategies devised to assemble their intricate structures, stressing the main similarities and differences encountered in the work developed by different laboratories, as well as the variations introduced along the synthetic route when pursuing different alkaloids through a common strategy. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009) [source]


    Cascade Annulation Reactions To Access the Structural Cores of Stereochemically Unusual Strychnos Alkaloids

    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 10 2009
    Ricardo Delgado
    Abstract A new cascade annulation reaction has been developed to access the core structures of a novel family of strychnos alkaloids with a unique stereochemical arrangement. The new annulation cascade is facilitated by the development of a robust reaction sequence to access extremely sensitive N -acyliminium ions. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009) [source]


    Novel Alkaloids from Myrioneuron nutans

    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 9 2009
    Van Cuong Pham
    Abstract Two new alkaloids, dehydronitraramine (1) and N -formylmyrionine (2) were isolated from the leaves of Myrioneuron nutans, and their structures were determined from spectroscopic analysis, including mass spectrometry and 2D-NMR spectroscopy. The absolute configuration 8S, 9R, 10S of N -formylmyrionine (2) was established by N -formylation of the known (8S,9R,10S)-myrionine and then comparison of the optical rotation of the natural N -formylmyrionine (2) with that of the semi-synthetic (8S,9R,10S)- N -formylmyrionine. Dehydronitraramine (1) displayed a moderate antiplasmodial activity against Plasmodiumfalciparum with an IC50 value of 16 ,M, whereas both 1 and 2 showed a weak cytotoxicity against KB cells.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009) [source]


    Red Pyrroloquinoline Alkaloids from the Mushroom Mycena haematopus

    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 2 2008
    Silke Peters
    Abstract Four so far unknown red alkaloid pigments, haematopodin B (1) and the mycenarubins D (3), E (5) and F (6), were isolated from fruiting bodies of Mycena haematopus. The structures of these pyrroloquinoline alkaloids were established by 2D NMR spectroscopic and MS (ESI) methods. Their absolute configurations were determined by comparison of their CD spectra with that of haematopodin (2) or mycenarubin A (4). Metabolic profiling of the red pigments of intact and injured fruiting bodies revealed that the known degradation product haematopodin (2) originates from haematopodin B (1), which is the native main pigment of M. haematopus.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008) [source]


    Stereodivergent Diversity Oriented Synthesis of Piperidine Alkaloids,,

    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 22 2006
    Louis V. Adriaenssens
    Abstract Alkylidenetitanium reagents enable the reagent-controlled high throughput asymmetric synthesis of 2-substituted piperidines and rapid access to multiple cyclic imines using solid phase synthesis (SPS). The Schrock carbenes, generated by reduction of thioacetals, convert resin-bound esters into enol ethers. Treatment with acid releases amino ketones that are cyclized with TMSCl to give iminium salts. Reduction introduces a chiral centre at C-2, whose absolute stereochemistry is determined by a phenethylamine (PEA) chiral auxiliary. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006) [source]