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Excellent Platform (excellent + platform)

Distribution by Scientific Domains

Polymers and Materials Science	50%

Selected Abstracts

Ultrathin Te Nanowires: An Excellent Platform for Controlled Synthesis of Ultrathin Platinum and Palladium Nanowires/Nanotubes with Very High Aspect Ratio

ADVANCED MATERIALS, Issue 18 2009
Hai-Wei Liang
Uniform ultrathin Pt nanotubes, Pt and Pd nanowires with diameters of only several nanometers and a very-high aspect ratio of ,10,000 can be fabricated using ultrathin Te nanowires as both reducing agent and sacrificial template in ethylene glycol. The valences of metal precursors have a crucial effect on the morphology of the nanostructures. [source]

Proton Transport from Dendritic Helical-Pore-Incorporated Polymersomes

ADVANCED FUNCTIONAL MATERIALS, Issue 18 2009
Anthony J. Kim
Abstract The ability to add synthetic channels to polymersome (polymer vesicle) membranes could lead to novel membrane composites with unique selectivity and permeability. Proton transport through two different synthetic pores, self-assembled from either a dendritic dipeptide, (6Nf-3,4-3,5)12G2-CH2 -Boc-L-Tyr-L-Ala-OMe, or a dendritic ester, (R)-4Bp-3,4-dm8G1-COOMe, incorporated into polymersome membranes are studied. Polymersomes provide an excellent platform for studying such transport processes due to their robustness and mechanical and chemical stability compared to liposomes. It is found that the incorporated dendritic dipeptide and dendritic ester assemble into stable helical pores in the poly(ethylene oxide)-polybutadiene (PEO-PBD) polymersomes but not in the poly(2-methyloxazoline)-poly(dimethylsiloxane)-poly(2-methyl oxazoline) (PMOX-PDMS-PMOX) polymersomes. The incorporation is confirmed by circular dichroism (CD), changes in purely synthetic mechanical strength (e.g., areal expansion modulus) as assessed by micropipette aspiration, and cryo-TEM. In addition to the structural analyses, a transport measurement shows the incorporated dendritic helical pores allow facile transport of protons across the polymersome membranes after up to one month of storage. This integration of synthetic porous channels with polymersome substrates could provide a valuable tool for studying active transport processes in a composite membrane. These composites will ultimately expand the family of biologically inspired porous-membrane mimics. [source]

Advanced Light Microscopy and Portuguese Folklore

IMAGING & MICROSCOPY (ELECTRONIC), Issue 3 2006
ELMI Meeting 2006 at Ofir, Portugal
Those who may have asked themselves 6 years ago, when the European Light Microscopy Initiative (ELMI, http://cci.sahlgrenska.gu.se/elmi/) meeting took place for the first time, if this really is what the European community of microscopists was waiting for, have a clear answer by now: Yes!, the ELMI conference has developed into an excellent platform for communication between scientists, specialists and manufacturers. [source]

Applications of Nanoparticles in Biology,

ADVANCED MATERIALS, Issue 22 2008
Mrinmoy De
Abstract The wide variety of core materials available, coupled with tunable surface properties, make nanoparticles an excellent platform for a broad range of biological and biomedical applications. This Review provides an introduction to nanoparticle,biomolecular interactions as well as recent applications of nanoparticles in biological sensing, delivery, and imaging of live cells and tissues. [source]

Electrocatalysis and determination of uracil on polythionine/multiwall carbon nanotubes modified electrode

JOURNAL OF APPLIED POLYMER SCIENCE, Issue 5 2008
Hongying Liu
Abstract A new type of poly (thionine)/multiwall carbon nanotube/glassy carbon (PTH/MWNTs/GC) electrode was fabricated by electropolymerization thionine onto the surface of MWNTs modified GC electrode. The properties and behaviors of the modified electrode were characterized by scanning electron microscopy (SEM) and cyclic voltammetry (CV). The results show that the high sensitivity and selectivity are mainly caused by the unique carbon surface of the carbon nanotubes and the catalytic activity of thionine. The modified electrode exhibited excellent electrocatalytic behavior to the oxidation of uracil, and was firstly applied to determinate the concentration of uracil for the differential pulse voltammograms. Under the optimum conditions, linear calibration equation was obtained over the uracil concentration range from 1.0 × 10,5 to 5.5 × 10,2M with a correlation coefficient of 0.9978 and a detection limit 2.0 × 10,7M (based on S/N = 3) was also gained. The good electrocatalytic response of uracil at PTH/MWNTs/GC electrode suggests that the PTH/MWNTs are an excellent platform for electrochemical biosensing. The modified electrode displays excellent repeatability, stability, and high sensitivity. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci, 2008 [source]

The organizational knowledge iceberg: An empirical investigation

KNOWLEDGE AND PROCESS MANAGEMENT: THE JOURNAL OF CORPORATE TRANSFORMATION, Issue 2 2009
Sajjad HaiderArticle first published online: 11 APR 200
This study explores the critical success factors of implementing and running a knowledge management program. In doing so, the paper proposes and tests a conceptual model of "knowledge iceberg" inside the organization using a case study methodology. In total 89 in-depth semi-structured interviews were conducted over a period of 1 year in the SoftNetCo company to study success factors in the implementation of knowledge initiatives. During the research period 11 knowledge management initiatives were launched in the company which provided an excellent platform to conduct this research. The findings of the study suggest the existence of a knowledge iceberg inside organizations. It is reported that six activities can cause the knowledge iceberg to rise which is critical for the success of knowledge management initiatives. It is further argued that a holistic approach is required to manage knowledge, people, and culture and that managers have to concentrate more on managing people than the knowledge itself. Copyright © 2009 John Wiley & Sons, Ltd. [source]

The shaft torque change in a laboratory scraped surface heat exchanger used for making ice slurries

ASIA-PACIFIC JOURNAL OF CHEMICAL ENGINEERING, Issue 6 2007
Frank G. F. Qin
Abstract In this paper, extensive laboratory test results of a scraped surface heat exchanger for making ice slurries are reported. The data have been analysed and interpreted. Some sensible conclusions have been obtained that should provide an excellent platform for developing further fundamental understanding of the phenomena and establishing a practical guide for design. Copyright © 2007 Curtin University of Technology and John Wiley & Sons, Ltd. [source]

scFv-based fluorogen activating proteins and variable domain inhibitors as fluorescent biosensor platforms

BIOTECHNOLOGY JOURNAL, Issue 9 2009
Crystal N. Falco
Abstract Single chain antibodies (scFvs) are engineered proteins composed of IgG variable heavy (VH) and variable light (VL) domains tethered together by a flexible peptide linker. We have characterized the individual VH or VL domain activities of several scFvs isolated from a yeast surface-display library for their ability to bind environmentally sensitive fluorogenic dyes causing them to fluoresce. For many of the scFvs, both VH and VL domains are required for dye binding and fluorescence. The analysis of other scFvs, however, revealed that either the VH or the VL domain alone is sufficient to cause the fluorogenic dye activation. Furthermore, the inactive complementary domains in the original scFvs either contribute nothing to, or actually inhibit the activity of these active single domains. We have explored the interactions between active variable domains and inactive complementary domains by extensive variable domain swapping through in vitro gene manipulations to create hybrid scFvs. In this study, we demonstrate that significant alteration of the fluorogenic dye activation by the active VH or VL domains can occur by partnering with different VH or VL complementary domains in the scFv format. Hybrid scFvs can be generated that have fluorogen-activating domains that are completely inhibited by interactions with other domains. Such hybrid scFvs are excellent platforms for the development of several types of genetically encoded, fluorescence-generating biosensors. [source]