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Selected AbstractsValidity of a Discharge Diagnosis of Heart Failure: Implications of MisdiagnosingCONGESTIVE HEART FAILURE, Issue 4 2008Cândida Fonseca MD Heart failure (HF) costs are largely due to hospitalization. The validity of a death/discharge diagnosis of HF (DDHF) is largely unknown. The authors assessed the validity of DDHF and the impact of misdiagnosing. The case notes of patients consecutively admitted to a medical department between January and June 2001 were reviewed. Cases with DDHF or cardiovascular diseases, potential precursors of HF (PPHF), were included. The diagnosis of HF (European Society of Cardiology guidelines) was classified as definite, possible, or miscoded. Of the 1038 patients admitted, 234 were enrolled: 157 with DDHF and 77 with PPHF. One hundred eighty patients had a definite diagnosis of HF. Of the 157 diagnoses coded as definite HF, 130 were correct, 21 had possible HF, and 6 were miscoded. Of the 77 patients classified as having PPHF, 38 had definite HF. The accuracy of the DDHF diagnosis was 72.2%: 21.1% were underdiagnosed and 8.3% overdiagnosed. DDHF failed to capture many HF admissions and therefore alone underestimates the prevalence, burden, and costs of the syndrome. [source] 8th Congress of the European Society of Contact DermatitisCONTACT DERMATITIS, Issue 5 200516 September 200, Berlin, Germany No abstract is available for this article. [source] International survey on esophageal cancer: part II staging and neoadjuvant therapyDISEASES OF THE ESOPHAGUS, Issue 3 2009J. Boone SUMMARY The outcome of esophagectomy could be improved by optimal diagnostic strategies leading to adequate preoperative patient selection. Neoadjuvant therapy could improve outcome by increasing the number of radical resections and by controlling metastatic disease. The purposes of this study were to gain insight into the current worldwide practice of staging modalities and neoadjuvant therapy in esophageal cancer, and to detect intercontinental differences. Surgeons with particular interest in esophageal surgery, including members of the International Society for Diseases of the Esophagus, the European Society of Esophagology , Group d'Etude Européen des Maladies de l'Oesophage, and the OESO, were invited to participate in an online questionnaire. Questions were asked regarding staging modalities, neoadjuvant therapy, and response evaluation applied in esophageal cancer patients. Of 567 invited surgeons, 269 participated resulting in a response rate of 47%. The responders currently performing esophagectomies (n= 250; 44%) represented 41 countries across the six continents. Esophagogastroscopy with biopsy and computed tomography (CT) scanning were routinely performed by 98% of responders for diagnosing and staging esophageal cancer, while endoscopic ultrasound (EUS) and barium esophagography were routinely applied by 58% and 51%, respectively. Neoadjuvant therapy is routinely administered by 33% and occasionally by 63% of responders. Of the responders that administer identical neoadjuvant regimens to esophageal adenocarcinoma (AC) and squamous cell carcinoma, 54% favor chemoradiotherapy. For AC, chemotherapy is preferred by 31% of the responders that administer neoadjuvant therapy, whereas for squamous cell carcinoma, the majority of responders (38%) prefer chemoradiotherapy. Response to neoadjuvant therapy is predominantly assessed by CT scanning of the chest and abdomen (86%). Barium esophagography, EUS, and combined CT/PET scan are requested for response monitoring in equal frequency (25%). Substantial differences in applied staging modalities and neoadjuvant regimens were detected between surgeons from different continents. In conclusion, currently the most commonly applied diagnostic modalities for staging and restaging esophageal cancer are CT scanning of the chest and abdomen, gastroscopy, barium esophagography and EUS. Neoadjuvant therapy is routinely applied by one third of the responders. Intercontinental differences have been detected in the diagnostic modalities applied in esophageal cancer staging and in the administration of neoadjuvant therapy. The results of this survey provide baseline data for future research and for the development of international guidelines. [source] A proposal to redefine familial combined hyperlipidaemia , Third workshop on FCHL held in Barcelona from 3 to 5 May 2001, during the Scientific Sessions of the European Society for Clinical InvestigationEUROPEAN JOURNAL OF CLINICAL INVESTIGATION, Issue 2 2002A. D. Sniderman No abstract is available for this article. [source] Quantitative Chemical Mapping of Relevant Trace Elements at Biomaterials/Biological Media Interfaces by Ion Beam MethodsADVANCED ENGINEERING MATERIALS, Issue 7 2010Edouard Jallot The definition of biomaterial as proposed by the European Society for Biomaterials in 1986 puts forward the overall importance of the notion of contact between the biomaterial and biological medium (cell, tissue, fluid,,). The underlying concept of biocompatibility makes the interface between biomaterial and biological medium a privileged zone of interest. In this paper, we would like to give an exhaustive view of how ion beams techniques can contribute to a better understanding of such interface taking several examples dealing with bone tissue substitution. After a short presentation of ion beams techniques the paper will focus on PIXE/RBS spectroscopies and will give the basics of these coupled technique. Three examples will then be presented to illustrate the interest of these techniques to study biomaterials/biological interactions. The first example deals with metallic alloys based joint prostheses. The ionic release from the prosthesis and the wear behavior of total knee prostheses will be presented. In the last two examples, bioactive materials will be studied. The common characteristic of bioactive ceramics is the kinetic modification of their surface upon interaction which is ideally monitored by PIXE chemical mapping. The second example will review the benefit of using PIXE/RBS technique to study the effect of doping of bioactive glasses on the very first steps involved in the bioactivity mechanisms like dissolution, ionic release, and biomineralization onto the surface of the glasses. Finally, protein delivery systems based upon mesoporous hydroxyapatites will be studied. Chemical mapping allowing the quantitative determination of protein distribution inside the HAp grains will be presented for the first time. [source] 40 abstracts relating to the Meeting of European Society of Cardiology Working Group on Cardiovascular Pharmacology and Drug Therapy & 3rd World Conference of International Academy of Cardiovascular Sciences June 18,19, 2009,Copenhagen, DenmarkFUNDAMENTAL & CLINICAL PHARMACOLOGY, Issue 1 2010Article first published online: 4 JAN 2010 First page of article [source] Periapical status and quality of endodontic treatment in an adult Irish populationINTERNATIONAL ENDODONTIC JOURNAL, Issue 2 2005J. J. Loftus Abstract Aim, To determine the prevalence of apical periodontitis and the quality of root fillings in an adult Irish population using a retrospective analysis of orthopantomograms (OPGs). Methodology, A systematic sample of clinical records and OPGs of 302 adult patients attending the Dublin Dental Hospital, Ireland, were screened by two examiners to determine the quality of root canal treatment and the prevalence of apical periodontitis. The operators who carried out the treatment were unknown. Two examiners inspected OPGs after inter-examiner correlation. European Society of Endodontology (ESE) guidelines were used to determine adequacy of root treatment. Results, Of the 7427 teeth examined 2% had root fillings. Apical periodontitis was evident in 1.6% of all nonroot filled teeth whilst 33.1% of the subjects had at least one tooth with apical periodontitis. Of the root filled teeth, 25% had apical periodontitis and 52.6% were considered technically inadequate by ESE guidelines. There was a statistically significant (P < 0.05) negative correlation between the quality of the root fillings and the prevalence of apical periodontitis. Posterior root filled teeth (premolars and molars) had a greater prevalence of apical periodontitis than anterior root filled teeth. Conclusions, The technical quality of root fillings in an adult Irish population was poor and was consistent with a high prevalence of apical periodontitis. [source] 10th Biennial Congress of the European Society of Endodontology, Munich, Germany 4th,6th October 2001INTERNATIONAL ENDODONTIC JOURNAL, Issue 3 2002John Whitworth First page of article [source] Wladimir Adlivankine European Society of Endodontology Research PrizeINTERNATIONAL ENDODONTIC JOURNAL, Issue 1 2002Article first published online: 25 JAN 200 First page of article [source] Maximising antihypertensive effects of angiotensin II receptor blockers with thiazide diuretic combination therapy: focus on irbesartan/hydrochlorothiazideINTERNATIONAL JOURNAL OF CLINICAL PRACTICE, Issue 12 2007J. M. Flack Summary Background:, Evidence-based guidelines for the management of hypertension are now well established. Studies have shown that more than 60% of patients with hypertension will require two or more drugs to achieve current treatment targets. Discussion:, Combination therapy is recommended as first-line treatment by the JNC-7 guidelines for patients with a blood pressure > 20 mmHg above the systolic goal or 10 mmHg above the diastolic goal, while the International Society of Hypertension in Blacks recommends combination therapy when BP exceeds targets by > 15/10 mmHg. Current European Society of Hypertension-European Society of Cardiology guidelines also recommend the use of low-dose combination therapy in the first-line setting. Furthermore, JNC-7 recommends that a thiazide-type diuretic should be part of initial first-line combination therapy. Thiazide/diuretic combinations are available for a variety of classes of antihypertensive, including ACE inhibitors, angiotensin receptor blockers (ARBs), beta blockers and centrally acting agents. This article focuses on clinical data investigating the combination of an ARB, irbesartan, with the diuretic, hydrochlorothiazide. Conclusions:, These data indicate that the ARB/HCTZ combination has greater potency and a similar side effect profile to ARB monotherapy and represents a highly effective approach for attaining goal BP levels using a therapeutic strategy that very effectively lowers BP, is well tolerated and minimises diuretic-induced metabolic effects. [source] International Consensus on Nomenclature and Classification of Atrial Fibrillation: A Collaborative Project of the Working Group on Arrhythmias and the Working Group of Cardiac Pacing of the European Society of Cardiology and the North American Society of Pacing and ElectrophysiologyJOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, Issue 4 2003SAMUEL LÉVY M.D. No abstract is available for this article. [source] Consensus Statement from the Cardiac Nomenclature Study Group of Arrhythmias of the European Society of Cardiology, and the Task Force on Cardiac Nomenclature from the North American Society of Pacing and Electrophysiology on Living Anatomy of the Atrioventricular JunctionsJOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, Issue 11 2000DARLENE K. RACKER PH.D. [source] Consensus Statement from the Cardiac Nomenclature Study Group of Arrhythmias of the European Society of Cardiology, and the Task Force on Cardiac Nomenclature from the North American Society of Pacing and Electrophysiology on Living Anatomy of the Atrioventricular JunctionsJOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, Issue 11 2000Reply to the Editor [source] Arrhythmogenic Right Ventricular Dyspiasia/Cardiomyopathy:JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, Issue 7 2000Need for an International Registry. Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy. Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is a heart muscle disease characterized by peculiar right ventricular involvement and electrical instability that precipitates ventricular arrhythmias and sudden death. The purpose of the present consensus report of the Study Group of the European Society of Cardiology and the Scientific Council on Cardiomyopathies of the World Heart Federation is to review the considerable progress in our understanding of the etiopathogenesis, morbid anatomy, and clinical presentation of ARVD/C since its first description in 1977. This article will focus on the important hut still unanswered issues, mostly regarding risk stratification, clinical outcome, and management of affected patients. Because ARVD/C is relatively uncommon and any one center may have experience with only a few patients, an international registry is being established to accumulate information and enhance the numbers of patients that can be analyzed to answer the pending questions. The registry also will facilitate pathologic, molecular, and genetics research on the etiology and pathogenesis of the disease. Furthermore, availability of an international database will enhance awareness of this largely unrecognized condition among the medical community. Physicians are encouraged to enroll patients in the International Registry of ARVD/C. [source] How the European Society for Evolutionary Biology and the Journal of Evolutionary Biology were foundedJOURNAL OF EVOLUTIONARY BIOLOGY, Issue 6 2008STEPHEN C. STEARNS [source] Call for Symposia for the 9th Congress of the European Society for Evolutionary Biology, Leeds, UK, 2003JOURNAL OF EVOLUTIONARY BIOLOGY, Issue 2 2002Article first published online: 25 MAR 200 No abstract is available for this article. [source] Prevalence of celiac disease among school children in Punjab, North IndiaJOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, Issue 10 2006Ajit Sood Abstract Background:, Celiac disease, as of today, is said to exist in almost all parts of the world, although it is rare among people of purely African,Caribbean, Japanese and Chinese background. The disease has also been considered uncommon in India until recently. Hospital records have revealed an increasing trend of the disease in predominantly wheat-eating areas of North India. The aim of the present study was to determine the prevalence of celiac disease among school children in Punjab, North India. Methods:, The study was carried out in the Ludhiana district of Punjab, Northern India. A total of 4347 children aged 3,17 years attending different schools were enrolled. A structured questionnaire was used to collect sociodemographic data and symptoms and signs related to celiac disease and various sociodemographic factors. The screening for celiac disease for the suspected celiacs was done by testing for antitissue transglutaminase (anti-tTG) by indirect solid-phase immunometric assay (ELISA). All children with high anti-tTG whose parents consented underwent upper gastrointestinal endoscopy for small bowel biopsy from the second part of the duodenum. Histopathology was expressed according to the Marsh classification of 1992. Follow up was carried out among children who were put on a gluten-restricted diet, at monthly intervals for 3 months and every 3 months thereafter. The diagnosis of celiac disease was established on the basis of the revised European Society of Paediatric Gastroenterologists and Nutritionists (ESPGAN) criteria (confirmed cases). Results:, A total of 4347 school children (1967 girls, 2380 boys, age range 3,17 years) were screened for celiac disease. Out of these, 198 suspected children were identified for further evaluation. Twenty-one children tested positive for anti-tTG assay (10.6%, 95% confidence interval: 16.91,34.79). Seventeen of these 21 children agreed to undergo biopsy; of these, 14 had histological changes consistent with celiac disease and all these 14 children had clinical response to gluten restriction. Three children with high anti-tTG had normal mucosa on duodenal biopsy and were not labelled as being in the celiac disease group. In the final analysis the disease prevalence was one in 310 children. Conclusions:, This is the first study on celiac disease prevalence among school children from India. Although this disease frequency of one in 310 is thought to be an under-assessment, it clearly shows that celiac disease is not rare in wheat-eating areas of North India. [source] Hospitalized patients with acute decompensated heart failure: Recognition, risk stratification, and treatment reviewJOURNAL OF HOSPITAL MEDICINE, Issue S6 2008Alpesh Amin MD Abstract Acute decompensated heart failure (ADHF) has emerged as a major healthcare problem. It causes approximately 3% of all hospitalizations in the United States, with the direct medical cost of these hospitalizations estimated at $18.8 billion per year. Early recognition, risk stratification, and evidence-based treatment are crucial in reducing the morbidity, mortality, and costs associated with this disorder. Classic signs and symptoms of ADHF, such as rales, dyspnea, and peripheral edema, may be absent at hospital presentation and, even when present, are not specific to this disorder. As a result, serum B,type natriuretic peptide level is now used to rapidly and accurately detect ADHF. Multivariate analyses have identified renal dysfunction, hypotension, advanced age, hyponatremia, and comorbidities as significant and independent mortality risk factors. Based on these factors, mortality risk can be stratified from very low to very high using published algorithms that have been validated in independent populations. Evidence-based guidelines for the treatment of ADHF are available from both the European Society of Cardiology and the Heart Failure Society of America. In general, an intravenous loop diuretic, either alone or in combination with a vasodilator, is recommended as initial therapy in patients with volume overload, depending on the patient's clinical status. Use of inotropic agents should be limited to the small subset of patients with low-output syndrome and significant hypotension. In any event, frequent monitoring of clinical response is essential, with subsequent therapy determined by this response. Finally, focused patient education during hospitalization may help reduce readmissions for ADHF. Journal of Hospital Medicine 2008;3(Suppl 6):S16,S24. © 2008 Society of Hospital Medicine. [source] Low plasma adiponectin is associated with coronary artery disease but not with hypertension in high-risk nondiabetic patientsJOURNAL OF INTERNAL MEDICINE, Issue 5 2006M. CESARI Abstract. Objective., To investigate the association of plasma adiponectin levels with coronary artery disease (CAD), arterial hypertension (HT), and insulin resistance (IR) in nondiabetic Caucasian patients. Design., We measured plasma adiponectin levels, IR (HOMA index), and the CAD atherosclerotic burden (angiography-based modified Duke Index score) in 400 nondiabetic patients undergoing coronary angiography. HT was diagnosed by the European Society of Hypertension/European Society of Cardiology (ESH/ESC) guidelines or if patients were on antihypertensive treatment. Results., Coronary artery disease was found in 62% of the patients and ruled out in the rest (non-CAD group). Plasma adiponectin levels were inversely related to the CAD score (, = ,0.12, P = 0.029) and predicted the coronary atherosclerotic burden independent of other cardiovascular risk factors. However, they were similar in NT and HT and showed no correlation with blood pressure values. In non-CAD, but not in CAD patients, they were lower in patients with than without IR (8.3 ± 1.2 vs. 11.3 ± 1.3, respectively; P = 0.007). Conclusions., In nondiabetic high-risk Caucasian patients plasma adiponectin levels are inversely related to CAD severity and IR; however, they are not strongly related to blood pressure values. [source] ORIGINAL ARTICLE: Use of 3D imaging and awareness of GEC-ESTRO recommendations for cervix cancer brachytherapy throughout Australia and New ZealandJOURNAL OF MEDICAL IMAGING AND RADIATION ONCOLOGY, Issue 4 2010S Van Dyk Abstract Introduction:, A 2005 survey of practices indicated limited use of three-dimensional (3D) imaging modalities and planning methods in cervix cancer brachytherapy in Australia and New Zealand. However, advancing technologies and published recommendations are influencing change. This survey aims to identify both changes in practice and awareness and uptake of Groupe European de Curietherapie of the European Society for Therapeutic Radiology and Oncology (GEC-ESTRO) recommendations. Methods:, A survey was emailed to all radiotherapy departments with brachytherapy facilities. Twenty departments practise brachytherapy for cancer of the cervix. The survey consisted of five questions enquiring about use and type of 3D imaging; rate of reimaging and replanning; and contouring, prescribing and reporting practices. Results:, A 100% response rate was obtained. Sixty-five per cent of departments use 3D CT imaging to plan brachytherapy insertions. Thirty per cent of departments use two-dimensional (2D) x-rays. Four departments (20%) use a combination of imaging modalities including CT, ultrasound and MRI. Sixty-five per cent of departments reimage and replan for each insertion. Four departments (20%) contour, prescribe dose and report treatment according to GEC-ESTRO recommendations. Conclusions:, There has been a marked increase in the use of 3D imaging and awareness of GEC-ESTRO recommendations. Implementation and reporting of image-based gynaecological brachytherapy is strongly dependent on local resources and infrastructure. [source] 17th European Society for Neurochemistry Meeting 3rd Conference on Advances in Molecular Mechanisms of Neurological Disorders, Salamanca, Spain, 19,22 May, 2007JOURNAL OF NEUROCHEMISTRY, Issue 2007Article first published online: 25 APR 200 No abstract is available for this article. [source] 7th Congress of the European Society of GynecologyJOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH (ELECTRONIC), Issue 3 2007Article first published online: 15 JUN 200 [source] Diagnosis and treatment of atrial fibrillation in the acute care settingJOURNAL OF THE AMERICAN ACADEMY OF NURSE PRACTITIONERS, Issue 6 2010ACNP-BC, Fatima Nottingham MS Abstract Purpose: To discuss the causes of atrial fibrillation (AF), risk factors, and pathophysiology, and review current treatment guidelines for AF in the inpatient setting. Data sources: Peer-reviewed medical and nursing journals, American College of Cardiology (ACC), American Heart Association (AHA), and European Society of Cardiology (ESC) practice guidelines. Conclusions: There are many predisposing factors to AF and a variety of treatment modalities. Nurse practitioners (NPs) should acquaint themselves with the pathophysiology and evidence-based treatments in order to provide individually based care to patients. Implications for practice: Pharmacological management is often warranted in patients with AF. NPs must be aware of updated clinical evidence in order to properly treat patients to provide symptomatic relief and improve quality of life. [source] Basic knowledge in psychodermatologyJOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY & VENEREOLOGY, Issue 2 2007F Poot Abstract Background, The authors try to define the framework of this approach, what should be acquired by "well-informed" dermatologists and what is required to be a pyschodermatologist. Objective, To better define the necessary knowledge to practice psychodermatology. Results, 1) The first level is dermatology psychology: there is a psychotherapeutical implicit effect of the dermatological consultation with a goal that is not psychological change. This effect can be improved by acquiring better communication skills and information. The second level needs a possibility to change the emotional individual process and the relational context in a continuum between counselling and psychotherapy. To practice this level a complete psychotherapeutic education with some specificity is needed. This can be reached by a dermatologist also being a psychotherapist or by a team consisting of both dermatologist-psychotherapist. 2) The psychodermatological patient is characterized by alexithymia. He/she needs to be understood through the body language he/she presents. This kind of patient is coming from families where the theme of loss seems to dominate the histories and be associated with deep emotional experiences of separation anxiety. These characteristics must be known together with the different psychodermatological disorders and the mind-body interaction to handle these patients. 3) Taking all of this complexity into account, the psychodermatologist or the psychodermatological team should be able to integrate the different points and adapt attitudes to the patient's difficulty during the whole therapeutic process. 4) The evaluation of the problem should be done using psychological tools here described. Conclusion, The European Academy of Dermatology and Venereology (EADV) together with the European Society for Dermatology and Psychiatry (ESDaP) are able to provide the specific education for dermatologist and psychotherapist. In the future, they could be responsible for the recognition of these special abilities and treatments on a governmental and European political level. [source] European Society for Veterinary Neurology: Research Abstracts of the 16th Annual Symposium September 26,27, 2003, Prague, Czech RepublicJOURNAL OF VETERINARY INTERNAL MEDICINE, Issue 2 2005Article first published online: 5 FEB 200 First page of article [source] The standardization of terminology of lower urinary tract function in children and adolescents: Report from the standardization committee of the International Children's Continence Society (ICCS),NEUROUROLOGY AND URODYNAMICS, Issue 1 2007Tryggve Nevéus Abstract Purpose We updated the terminology in the field of pediatric lower urinary tract function. Materials and Methods Discussions were held in the board of the International Children's Continence Society and an extensive reviewing process was done involving all members of the International Children's Continence Society, the urology section of the American Academy of Pediatrics, the European Society of Pediatric Urology, as well as other experts in the field. Results and Conclusions New definitions and a standardized terminology are provided, taking into account changes in the adult sphere and new research results. Neurourol. Urodynam. 26:90,102, 2007. © 2006 Wiley-Liss, Inc. [source] Annual Meeting of the European Society for Paediatric ResearchPEDIATRIC DIABETES, Issue 4 2006Article first published online: 11 AUG 200 No abstract is available for this article. [source] 16th Meeting of the European Society for Pigment Cell Research 4,7 September 2010 Wellcome Trust Genome Campus, Hinxton, Cambridge, UKPIGMENT CELL & MELANOMA RESEARCH, Issue 4 2010Article first published online: 16 JUL 2010 First page of article [source] European Society for Pigment Cell Research 14th Meeting , Bari, 14 , 17 October 2007 Sheraton Nicolaus , Bari ,,Pigment cells and their environment"PIGMENT CELL & MELANOMA RESEARCH, Issue 5 2007Article first published online: 10 SEP 200 First page of article [source] 13th meeting of the European Society for Pigment Cell Research (ESPCR-2006) 24,27 September 2006, Barcelona, SpainPIGMENT CELL & MELANOMA RESEARCH, Issue 5 2006Article first published online: 28 JUN 200 First page of article [source] |