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European Laboratories (european + laboratory)

Distribution by Scientific Domains
Life Sciences40%
Engineering40%

Selected Abstracts

Base isolation for retrofitting historic buildings: Evaluation of seismic performance through experimental investigation

EARTHQUAKE ENGINEERING AND STRUCTURAL DYNAMICS, Issue 8 2001
Antonello De Luca
Abstract An experimental test program on a full-scale model representing a sub-assemblage of the cloister facade of the Sao Vicente de Fora monastery, retrofitted through base isolation, has been recently carried out at the European Laboratory for Structural Assessment of the Joint Research Centre of the European Commission. In this paper an overview of the laboratory model and the experimental results is provided. In particular, firstly the test model is described, including the geometry and mechanical properties of the masonry specimen and the design of the isolation devices; then the testing method and the sub-structuring of the isolation system are described and the seismic inputs adopted for the pseudo-dynamic tests are defined. Finally, the experimental results are discussed and compared to the analogous results obtained on the ,as is', fixed-base sub-assemblage model. The implications of the test outcomes are emphasized and developments of this research line are presented. Copyright © 2001 John Wiley & Sons, Ltd. [source]

Organizational emergence in networked collaboration

INTERNATIONAL JOURNAL OF COMMUNICATION SYSTEMS, Issue 7 2002
Ari-Pekka Hameri
Abstract Research on complex adaptive systems has generated several conceptual parables to explain systems with emergent behaviour. One prominent use for terms such as self-organization, evolutionary trajectories, co-evolution and punctuated equilibrium has been in understanding human organizations. In such systems, emergent behaviour is demonstrated in novel structures, processes and spin-offs that cannot be explained just by studying single components of the organization and the intelligence embedded in them. Instead of solely exploiting the qualitative explanatory power of the evolutionary concepts, this paper focuses also on quantitative methods to track emergent behaviour in a globally distributed, constantly fluctuating and highly networked project organization. The underlying case is that of CERN (CERN, the European Laboratory for Particle Physics, has its headquarters in Geneva. At present, its Member States are Austria, Belgium, the Czech Republic, Denmark, Finland, France, Germany, Greece, Hungary, Italy, Netherlands, Norway, Poland, Portugal, the Slovak Republic, Spain, Sweden, Switzerland and the United Kingdom. Israel, the Russian Federation, Turkey, Yugoslavia (status suspended after the UN embargo, June 1992), the European Commission and UNESCO have observer status.) and its decade long accelerator project, which strongly relies on electronic communication and networking to achieve its major objectives due to be accomplished by the year 2006. By using time series and self-organizing maps to analyse the global interaction among project groups and individuals the paper provides new insight to the understanding of emergent behaviour in human organizations. The key result of the study concerns the rigid deep structure of each case organization that seems to remain intact for the duration of the whole project. Copyright © 2002 John Wiley & Sons, Ltd. [source]

A method for the determination of polyunsaturated fatty acid methyl esters in biodiesel: Results of an interlaboratory study

EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, Issue 8 2009
Sigurd Schober
Abstract A gas chromatographic method for the determination of fatty acid methyl esters with four or more double bonds in biodiesel was developed and tested. The method is based on gas chromatographic separation on a wax capillary column using methyl tricosanoate as internal standard. The performance of the method was proved with the participation of 11,European laboratories by a Round Robin test on six different biodiesel samples containing different amounts of polyunsaturated fatty acid methyl esters. The results showed that the precision is sufficient around the EN,14214 limit of 1,% (m/m). At lower concentrations the variation is too high. The scope of the application can be given between as 0.6 and 1.5%. [source]

External quality assessment of rapid prenatal detection of numerical chromosomal aberrations using molecular genetic techniques: 3 years experience

PRENATAL DIAGNOSIS, Issue 5 2007
S. C. Ramsden
Abstract Objectives Prenatal diagnosis using rapid molecular genetic techniques is now a widely used method for detecting the most prevalent chromosomal aneuploidies. The object of this work was to develop a methodology for delivering external quality assessment (EQA) appropriate to the needs of routine diagnostic testing laboratories. Methods We have provided three rounds of EQA using 15 different samples over 3 years. The scheme has developed to assess both the genotyping accuracy of the results and the appropriateness of the clinical reports issued to the referring clinician. Results Participation in the EQA scheme has increased from 9 to 27 laboratories from across Europe over the three sample distributions. All laboratories have used quantitative fluorescence-PCR (QF-PCR) to analyse these samples except for a sole participant in 2006 who used multiplex ligation-dependent probe amplification (MLPA). In total 265 samples have been distributed, of which four (1.5%) were not reported due to technical failures and one (0.4%) was reported incorrectly and must be regarded as a genotyping error. Conclusions We have demonstrated a significant and increasing demand for EQA in the rapid detection of aneuploidies in UK and other European laboratories. Using the methodologies described, we have had a very low rate of technical failures and demonstrated a high level of genotyping accuracy. However, the quality of the clinical reports was variable and suggestions are made for improvement. Copyright © 2007 John Wiley & Sons, Ltd. [source]

Inter-laboratory comparison of elemental analysis and gas chromatography/combustion/isotope ratio mass spectrometry.

RAPID COMMUNICATIONS IN MASS SPECTROMETRY, Issue 7 2009
15N measurements of selected compounds for the development of an isotopic Grob test
An inter-laboratory exercise was carried out by a consortium of five European laboratories to establish a set of compounds, suitable for calibrating gas chromatography/combustion/isotope ratio mass spectrometry (GC-C-IRMS) devices, to be used as isotopic reference materials for hydrogen, carbon, nitrogen and oxygen stable isotope measurements. The set of compounds was chosen with the aim of developing a mixture of reference materials to be used in analytical protocols to check for food and beverage authentication. The exercise was organized in several steps to achieve the certification level: the first step consisted of the a priori selection of chemical compounds on the basis of the scientific literature and successive GC tests to set the analytical conditions for each single compound and the mixture. After elimination of the compounds that turned out to be unsuitable in a multi-compound mixture, some additional oxygen- and nitrogen-containing substances were added to complete the range of calibration isotopes. The results of ,13C determinations for the entire set of reference compounds have previously been published, while the ,D and ,18O determinations were unsuccessful and after statistical analysis of the data the results did not reach the level required for certification. In the present paper we present the results of an inter-laboratory exercise to identify and test the set of nitrogen-containing compounds present in the mixture developed for use as reference materials for the validation of GC-C-IRMS analyses in individual laboratories. Copyright © 2009 John Wiley & Sons, Ltd. [source]