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Ethanol Molecules (ethanol + molecule)
Selected AbstractsSynthesis and Characterisation of Coordination Polymers of CuII and ZnII with 1,3-Bis(1,2,3,4-tetrazol-2-yl)propane , Rotational Freedom of the Donor Group Favours Structural DiversificationEUROPEAN JOURNAL OF INORGANIC CHEMISTRY, Issue 18 2004Robert Bronisz Abstract The novel bidentate ligand 1,3-bis(1,2,3,4-tetrazol-2-yl)propane (pbtz), which possesses a flexible spacer, was synthesised in order to investigate the influence of the flexibility of ligand molecules on the architecture of coordination polymers. For that purpose the reactions between pbtz and M(ClO4)2·6H2O salts (M = CuII and ZnII) were performed. The complexes [{Cu(pbtz)3}(ClO4)2], and [{Zn(pbtz)3}(ClO4)2·2EtOH], were characterised by IR and UV/Vis spectroscopy and their crystal structures were determined by single-crystal X-ray diffraction measurements. In both compounds the pbtz ligand molecules act as N4,N4, connectors bridging the central atoms, and the 2-substituted tetrazole rings coordinate in a monodentate fashion to the central atoms forming M(tetrazole)6 cores. [{Cu(pbtz)3}(ClO4)2], was isolated as a 1D coordination polymer. The copper(II) ions are triply bridged by ligand molecules, leading to the formation of infinite 1D chains. A highly unusual manner of bridging, with the tethering of two neighbouring central atoms by the same kind of ligand molecules, although possessing different conformations, is observed. In [{Zn(pbtz)3}(ClO4)2·2EtOH], the six-coordinate zinc(II) ions, which are bridged by single ligand molecules, serve as topological nodes, leading to the formation of a 3D ,-polonium-type network. The crystal structure of the ZnII complex contains only one such net solvated by ethanol molecules. A conformational analysis of the ligand molecules in both compounds demonstrates that the flexibility of the pbtz and the ability of the tetrazole rings in particular to adopt various, relative orientations is responsible for the diversity of the architectures of the obtained complexes. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004) [source] Clindamycin hydrochloride monohydrate and its ethanol solvateACTA CRYSTALLOGRAPHICA SECTION C, Issue 2 2010Krishnan Ravikumar Clindamycin hydrochloride, an antibiotic of the lincomycin family, was crystallized as the monohydrate, namely (2S,4R)-2-(N -{(1S,2S)-2-chloro-1-[(3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)perhydropyran-2-yl]propyl}aminocarbonyl)-4-propylpyrrolidinium chloride monohydrate, C18H34ClN2O5S+·Cl,·H2O, (I), and as the monohydrate ethanol solvate, C18H34ClN2O5S+·Cl,·H2O·C2H6O, (II). The conformation of the clindamycin molecule in both crystal structures is the same and is found to be similar to that in enzyme-bound clindamycin. The simultaneous presence of free chloride ions and water molecules in (I) and of additional ethanol molecules in (II) provides an interesting network of hydrogen bonds. The significance of this study lies in the interactions in these structures and the aggregations occurring via hydrogen bonds in the hydrated and solvated crystalline forms of the title compound. [source] Manganese(II) and cobalt(II) complexes of 1,4-bis(diphenylphosphinoyl)butaneACTA CRYSTALLOGRAPHICA SECTION C, Issue 1 2009Anthony M. J. Lees The title complexes, catena -poly[[[diaquadiethanolmanganese(II)]-,-1,4-bis(diphenylphosphinoyl)butane-,2O:O,] dinitrate 1,4-bis(diphenylphosphinoyl)butane solvate], {[Mn(C2H6O)2(C28H28O2P2)(H2O)2](NO3)2·C28H28O2P2}n, (I), and catena -poly[[[diaquadiethanolcobalt(II)]-,-1,4-bis(diphenylphosphinoyl)butane-,2O:O,] dinitrate 1,4-bis(diphenylphosphinoyl)butane solvate], {[Co(C2H6O)2(C28H28O2P2)(H2O)2](NO3)2·C28H28O2P2}n, (II), are isostructural and centrosymmetric, with the MII ions at centres of inversion. The coordination geometry is octahedral, with each metal ion coordinated by two trans ethanol molecules, two trans water molecules and two bridging 1,4-bis(diphenylphosphinoyl)butane ligands which link the coordination centres to form one-dimensional polymeric chains. Parallel chains are linked by hydrogen bonds to uncoordinated 1,4-bis(diphenylphosphinoyl)butane molecules, which are bisected by a centre of inversion. Further hydrogen bonds, weak C,H...O interactions to nitrate anions, and weak C,H..., interactions serve to stabilize the structure. This study reports a development of the coordination chemistry of bis(diphenylphosphinoyl)alkanes, with the first reported structures of complexes of the first-row transition metals with 1,4-bis(diphenylphosphinoyl)butane. [source] Synthesis and X-ray study of the 6-(N -pyrrolyl)purine and thymine derivatives of 1-aminocyclopropane-1-carboxylic acidCHEMICAL BIOLOGY & DRUG DESIGN, Issue 5 2004M. Cetina Abstract:, The novel purine and pyrimidine derivatives of 1-aminocyclopropane-1-carboxylic acid 1 and 2 were obtained by alkylation of 6-(N -pyrrolyl)purine and thymine with methyl 1-benzamido-2-chloromethylcyclopropanecarboxylate. X-ray crystal structure analysis shows that the cyclopropane rings in 1 and 2 posses Z -configuration. The cyclopropane ring atoms and attached atoms of the benzamido and methoxycarbonyl moiety of both molecules are disposed perpendicularly to each other. The carbonyl oxygen of the methoxycarbonyl moiety adopts in both compounds a synperiplanar conformation with respect to the midpoint of the distal bond of the cyclopropane ring. The torsion angles , and , for the 1-aminocyclopropane-1-carboxylic acid residue in 1 and 2 correspond to a folded conformation, while the torsion angles , define antiperiplanar conformation. Intermolecular hydrogen bonds connect the molecules of 1 into dimers. Each dimer is hydrogen-bonded with four ethanol molecules, thus forming discrete unit. On the contrary, intermolecular hydrogen bonds link the molecules of 2 generating three-dimensional network. [source] | ||||||||||