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Aggressive Surgical Intervention (aggressive + surgical_intervention)

Distribution by Scientific Domains

Medical Sciences	100%

Selected Abstracts

Aggressive Squamous Cell Carcinoma Originating as a Marjolin's Ulcer

DERMATOLOGIC SURGERY, Issue 2 2004
Shawn R. Sabin MD
Background. Marjolin's ulcer is an epidermoid carcinoma arising in a scar or chronic wound and can have an aggressive course. Objective. To present a case of squamous cell carcinoma arising in a burn scar with resulting metastases and to discuss Marjolin's ulcer. Results. The patient continued to have further metastatic disease despite aggressive surgical treatment. Conclusion. In following patients with chronic ulcers and wounds, it is important to evaluate any changes immediately with biopsies and further imaging studies if indicated in order to treat effectively. Even aggressive surgical intervention will sometimes be inadequate in treating these tumors. [source]

Necrotizing fasciitis in adolescents with poorly controlled type 1 diabetes mellitus: report of two cases

PEDIATRIC DIABETES, Issue 6 2007
Louise S Conwell
Abstract:, Necrotizing fasciitis (NF) is a potentially fatal bacterial infection of the subcutaneous soft tissues. Two cases of polymicrobial NF in adolescents with type 1 diabetes mellitus and poor glycemic control are reported. The perineal region was involved in both cases. One case was precipitated by apparently minimal trauma, the other by high-impact trauma. Diabetes mellitus has been identified as a common comorbidity and predictor of increased mortality in adult patients with NF. The associations between diabetes and the incidence or outcome of NF in children and adolescents are not known. In all cases, early identification and aggressive surgical intervention are important for limiting morbidity and mortality. [source]

Targeted Tailored Management of the Breast Cancer Patient at Risk for Harboring a Germline Mutation,Current Trends Affecting the Selection of Patients Considering Surgical Prophylaxis for Breast Cancer

THE BREAST JOURNAL, Issue 2009
Edibaldo Silva MD
Abstract:, Recent reports have documented the increasing use of mastectomy in women with breast cancer otherwise amenable to breast conservation. Similarly, other reports document an increase in the number of women undergoing contra-lateral prophylactic mastectomy for a single unilateral breast cancer. These trends are abetted by increasing use of MRI, inadequate risk counseling, and patient fear. Adequate and reliable risk assessment and genetic counseling are indispensable for the appropriate and personalized treatment of these individuals. In all of these instances, such counseling should be instituted well before the patients are submitted to any surgical intervention. An algorithm is presented which permits the orderly selection of patients who may benefit from such aggressive surgical intervention. [source]

A fatal case of cutaneous zygomycosis in a patient with severe metabolic acidosis

MYCOSES, Issue 4 2009
C. Kosmidis
Summary We present a case of cutaneous zygomycosis in a patient with an ureteroileostomy and severe metabolic acidosis, but without diabetes. The patient died despite multiple aggressive surgical interventions and antifungal therapy with liposomal amphotericin B. Ureteroileostomy-related acidosis can be a predisposing factor for zygomycosis. Metabolic acidosis can have a role in the severity of cutaneous disease. [source]